1.Congenital insensitivity to pain with anhidrosis: a case report.
Joon Sung KIM ; Young Jong WOO ; Geun Mo KIM ; Chan Jong KIM ; Jae Sook MA ; Tai Ju HWANG ; Min Cheol LEE
Journal of Korean Medical Science 1999;14(4):460-464
Congenital insensitivity to pain with anhidrosis (CIPA) is a very rare genetic disorder of the peripheral nervous system characterized by recurrent episodes of unexplained fever, generalized anhidrosis, insensitivity to pain and temperature, and accompanied by self-mutilating behavior and mental retardation. We report on a 16 month-old boy with CIPA who exhibited these characteristic clinical features. A sural nerve biopsy revealed markedly reduced numbers of unmyelinated and small myelinated fibers, consistent with the characteristic features of CIPA.
Atrophy
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Case Report
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Fingers
;
Human
;
Hypohidrosis/pathology*
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Hypohidrosis/complications
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Infant
;
Korea
;
Male
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Mental Retardation/pathology
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Mental Retardation/complications
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Microscopy, Electron
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Nerve Fibers/ultrastructure
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Nerve Fibers/pathology
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Pain Insensitivity, Congenital/pathology*
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Pain Insensitivity, Congenital/complications
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Self Mutilation/pathology
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Self Mutilation/etiology
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Sural Nerve/pathology
;
Tongue
2.Self-inflicted Chronic Bacterial Keratoconjunctivitis Using Self Semen.
Youngsub EOM ; Young Ho KIM ; Seung Hyun KIM ; Hyo Myung KIM ; Jong Suk SONG
Korean Journal of Ophthalmology 2013;27(6):459-462
This case report describes a case of self-inflicted chronic bacterial keratoconjunctivitis involving the patient's own semen. A 20-year-old male soldier was referred to our clinic for the evaluation of refractory chronic bacterial conjunctivitis. Over the previous 4 months, he had been treated for copious mucous discharge, conjunctival injection, and superficial punctate keratitis in both eyes at an army hospital and a local eye clinic. Despite the use of topical and systemic antibiotics according to the results of conjunctival swab culture, there was no improvement. During the repeated smear and culture of conjunctival swabs, surprisingly, a few sperm were detected on Gram staining, revealing that the condition was self-inflicted bacterial keratoconjunctivitis involving the patient's own semen. Thus, in cases of chronic keratoconjunctivitis that do not respond to appropriate antibiotic treatment, self-inflicted disease or malingering should be considered.
Chronic Disease
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Conjunctiva/*injuries/microbiology/pathology
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Cornea/microbiology/*pathology
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Diagnosis, Differential
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Eye Infections, Bacterial/diagnosis/*etiology/microbiology
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Eye Injuries/*complications/diagnosis
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Humans
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Keratoconjunctivitis/diagnosis/*etiology/microbiology
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Male
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Self Mutilation/*complications/diagnosis
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*Semen
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Young Adult