No abstract available.
Radionuclide Imaging*

No abstract available.
Cardiomyopathy, Hypertrophic*

OBJECTIVE: To evaluate the degree of streptococcal colonization in Korean pregnant women. METHODS: The study comprised of 153 singleton pregnant women who visited Severance Hospital for delivery, and their neonates. Specimens for GBS culture were collected by a sterile cotton swab from lower vagina and cervix of pregnant women, and from ear canal and throat of neonates. They were first cultured for 48 hours in Todd-Hewitt broth and then subcultured onto Tryptose blood agar plates(Difco). Group B streptococci were confirmed by the presence of beta-hemolysis and a positive reaction with Phadebact group B Streptococci reagent(Karo Biodiagnostics AB, Huddinge, Sweden). RESULTS: The prevalence of positive cultures in pregnant women and neonates were 2.61%(4/153) and 0%(0/4), respectively. In the study population there was a case of suspicious group B streptococcual sepsis in an infant whose mother was colonized. CONCLUSIONS: In our study the GBS colonization rate in Korean pregnant women was significantly lower than that of other countries. The reason for this difference may be associated with a racial differences, or social factors such as socio-economic status or a life style.
Agar ; Cervix Uteri ; Colon ; Ear Canal ; Female ; Humans ; Infant ; Infant, Newborn ; Life Style ; Mothers ; Pharynx ; Pregnancy ; Pregnant Women* ; Prevalence ; Sepsis ; Streptococcal Infections* ; Vagina

No abstract available.
Epinephrine*

No abstract available.
Epinephrine*

The etiology of neural tube defects, a category encompassing spina bifida, anencephaly and encephalocele, remains highly controversial and unclear, However, there is overwhelming evidence supporting a multifactorial etiology for this group of defects. Recent studies have shown that folic acid supplements taken periconceptionally can reduce a woman's risk of having a child with a neural tube defect. Qenetic screening could identify women who will require folic acid supplements periconceptionally to reduce their risk of having a child with a neural tube defects. Recently, we encountered two cases of recurrent anencephaly that had occurted in a same pregnant woman in our hospital. We report these two cases with brief review of the literatures.
Anencephaly* ; Child ; Encephalocele ; Female ; Folic Acid ; Humans ; Mass Screening ; Neural Tube Defects ; Pregnant Women* ; Spinal Dysraphism

No abstract available.
Humans ; Infant, Newborn* ; Mass Screening*

PURPOSE: Williams syndrome(WS) is an autosomal dominant disorder resulting from a submicroscopic deletion of contiguous genes on the long arm of chromosome 7. We evaluated the physical, neurodevelopmental, and behavioral characteristics of children and adults with WS confirmed by fluorescence in situ hybridization. METHODS: The clinically suspicious twelve cases with cardiac anomaly were confirmed as WS with fluorescence in situ hybridization(FISH) using the bacterial artificial chromosome clone 244H3, which has the genomic DNA sequence of elastin, as a probe. The neonatal history, facial features, associated anomaly including heart disease, neurological and behavioral characteristics were reviewed. RESULTS: During the first year, infants with WS showed irritability(83%), vomiting, failure to thrive(58%), and feeding problems(50%). Inguinal and umbilical hernias were common(67%). The associated cardiac anomalies were supravalvular aortic stenosis(83%), most commonly and peripheral pulmonary stenosis(25%) and coarctatin of aorta(8%). The facial findings were periorbital swelling(100%), full and drooping cheek, thick lips, open wide mouth, full nasal tip(83%). Abnormal facial appearance became more striking during childhood and then more coarse by adolescence. Walking alone occurred at an average age of 24 months. Average I.Q. of about 62, with a range from 46 to 75(62+/-12) was recorded. The perceptual, especially visuospatial and motor funtions were more impaired than verbal performance. Distractibility, poor concentration and talk ativeness were very common. Aggressive behaviour was less common. CONCLUSION: We conclude that molecular genetic analysis of 22q11 should be considered in patients with 1) supravalvular aortic stenosis or peripheral pulmonry stenosis, and 2) facial dysmorpholgy and 3) mental retardation with a friendly, outgoing personality, and 4) miserable infantile life with feeding problems such as vomiting and colic.
Adolescent ; Adult ; Aortic Stenosis, Supravalvular ; Arm ; Base Sequence ; Cheek ; Child ; Chromosomes, Artificial, Bacterial ; Chromosomes, Human, Pair 7 ; Clone Cells ; Colic ; Constriction, Pathologic ; Elastin ; Fluorescence ; Heart Diseases ; Hernia, Umbilical ; Humans ; In Situ Hybridization ; Infant ; Intellectual Disability ; Lip ; Molecular Biology ; Mouth ; Strikes, Employee ; Vomiting ; Walking ; Williams Syndrome*

We report a patient with a left anterior cerebral artery (ACA) infarct showing representational neglect. Representational neglect is some form of neglect to areas of imagined space. We believe that the description of our case gives further information about neglect syndrome and the functional asymmetry of the cerebral hemispheres because these observations are rare.
Anterior Cerebral Artery* ; Cerebrum ; Humans ; Infarction, Anterior Cerebral Artery*

We retrospectively reviewed all cases of hydrocephalus shunted in the Soonchunhyang University Hospital within a 5-year period and encountered 12 cases of posttraumatic hydrocephalus. When admitted, seven patients had a Glasgow Coma Scale value of 8 or less and, of the five patients with a Glasgow Coma Scale value above 8, two had an intraventricular hemorrhage, two had a subarachnoid hemorrhage alone. The mean interval from injury to the shunt was 110 days(range from 4 to 311 days). The intracranial pressure was measured by lumbar puncture in eight patients. It was less then 200mmCSF in five patients and above 200mmCSF in three patients. After shunting, six patients(50%) improved markedly and four(33%) slightly. Overall outcome was good recovery in three, moderate disability in three, severe disability in three, vegetative state in two, and death in one patient. Several prognostic factors such as Glasgow Coma Scale value on admission, CT findings, intracranial pressure, interval from injury to the shunt, degree of cortical atrophy, and surgical method are not related to the result of the shunt(p>0.1 by Fisher's test). Since there are no accurate predictors for the result of shunt at present, one can not be sure that the patient with negative prognostic factors will not improve. Shunting rather than simple observation could be a suitable therapeutic trial especially for the bedridden patients.
Atrophy ; Glasgow Coma Scale ; Hemorrhage ; Humans ; Hydrocephalus* ; Intracranial Pressure ; Persistent Vegetative State ; Retrospective Studies ; Spinal Puncture ; Subarachnoid Hemorrhage