No abstract available.
Radionuclide Imaging*

No abstract available.
Cardiomyopathy, Hypertrophic*

No abstract available.
Epinephrine*

No abstract available.
Epinephrine*

OBJECTIVE: To evaluate the degree of streptococcal colonization in Korean pregnant women. METHODS: The study comprised of 153 singleton pregnant women who visited Severance Hospital for delivery, and their neonates. Specimens for GBS culture were collected by a sterile cotton swab from lower vagina and cervix of pregnant women, and from ear canal and throat of neonates. They were first cultured for 48 hours in Todd-Hewitt broth and then subcultured onto Tryptose blood agar plates(Difco). Group B streptococci were confirmed by the presence of beta-hemolysis and a positive reaction with Phadebact group B Streptococci reagent(Karo Biodiagnostics AB, Huddinge, Sweden). RESULTS: The prevalence of positive cultures in pregnant women and neonates were 2.61%(4/153) and 0%(0/4), respectively. In the study population there was a case of suspicious group B streptococcual sepsis in an infant whose mother was colonized. CONCLUSIONS: In our study the GBS colonization rate in Korean pregnant women was significantly lower than that of other countries. The reason for this difference may be associated with a racial differences, or social factors such as socio-economic status or a life style.
Agar ; Cervix Uteri ; Colon ; Ear Canal ; Female ; Humans ; Infant ; Infant, Newborn ; Life Style ; Mothers ; Pharynx ; Pregnancy ; Pregnant Women* ; Prevalence ; Sepsis ; Streptococcal Infections* ; Vagina

The etiology of neural tube defects, a category encompassing spina bifida, anencephaly and encephalocele, remains highly controversial and unclear, However, there is overwhelming evidence supporting a multifactorial etiology for this group of defects. Recent studies have shown that folic acid supplements taken periconceptionally can reduce a woman's risk of having a child with a neural tube defect. Qenetic screening could identify women who will require folic acid supplements periconceptionally to reduce their risk of having a child with a neural tube defects. Recently, we encountered two cases of recurrent anencephaly that had occurted in a same pregnant woman in our hospital. We report these two cases with brief review of the literatures.
Anencephaly* ; Child ; Encephalocele ; Female ; Folic Acid ; Humans ; Mass Screening ; Neural Tube Defects ; Pregnant Women* ; Spinal Dysraphism

PURPOSE: In newborns from mothers with Graves' disease, neonatal transient hyperthyroidism or hypothyroidism may develop early in life. We evaluated the incidence and prognosis of neonatal thyroid dysfunction in neonates born to mothers with hyperthyroidism during pregnancy. METHODS: We measured blood T4, T3, TSH levels and TSH-R-Ab titer in 48 hyperthyroid mothers and their babies between 1988 and 1994. RESULTS: The mean birth weight was 3.21+/-0.49kg and gestational age was 39+5 weeks and three neonates(6%) were small for gestational age and two(4%) were premature whose mother had hyperthyroidism during pregnancy. Eight of the neonates showed high levels of thyroid hormone and four showed low levels of thyroid hormone but none had symptom or sign. The neonatal thyroid function was not affected by maternal antithyroid medication and maternal TSH-R-Ab level. The positive rate of TSH-R-Ab was 44 percent in neonates. In the neonates with low T4 level, the mean TSH-R-Ab was 38.1+/-19.6%, which was higher than those in euthyroid(14.7+/-9.7%) or hyperthyroid(8.4+/-6.2%) neonates(p<0.05). The neonatal blood TSH-R-Ab levels was correlated with maternal TSH-R-Ab levels(r=0.50, p<0.05). Neonatal T4 didn't show any correlation with maternal TSH-R-Ab but showed negative correlation with neonatal TSH-R-Ab(r=-0.43, p<0.05). Neonates with high T4 showed normal thyroid function within 35 days(10-54days) in average. Neonates with low T4 showed normal thyroid function within 29 days(7-61days) in average. One of neonate with low T4 was given thyroid hormone for 1 month. No one with initial abnoraml thyroid function showed clinical problem through follow-up. CONCLUSIONS: It is likely that hyperthyroid mothers have more tendency of small babies for gestational age or premature babies. Neonates born to hyperthyroid mothers should be closely monitored because of possible abnormal thyroid function, as shown by this study. It is likely that TSH-R-Ab from hyperthyroid mother usually consists of blocking antibody, rather than stimulating antibody, which might cause hypothyroidism in the neonates.
Birth Weight ; Follow-Up Studies ; Gestational Age ; Graves Disease ; Humans ; Hyperthyroidism* ; Hypothyroidism ; Incidence ; Infant, Newborn* ; Mothers* ; Pregnancy ; Prognosis ; Thyroid Gland*

We report a patient with a left anterior cerebral artery (ACA) infarct showing representational neglect. Representational neglect is some form of neglect to areas of imagined space. We believe that the description of our case gives further information about neglect syndrome and the functional asymmetry of the cerebral hemispheres because these observations are rare.
Anterior Cerebral Artery* ; Cerebrum ; Humans ; Infarction, Anterior Cerebral Artery*

We retrospectively reviewed all cases of hydrocephalus shunted in the Soonchunhyang University Hospital within a 5-year period and encountered 12 cases of posttraumatic hydrocephalus. When admitted, seven patients had a Glasgow Coma Scale value of 8 or less and, of the five patients with a Glasgow Coma Scale value above 8, two had an intraventricular hemorrhage, two had a subarachnoid hemorrhage alone. The mean interval from injury to the shunt was 110 days(range from 4 to 311 days). The intracranial pressure was measured by lumbar puncture in eight patients. It was less then 200mmCSF in five patients and above 200mmCSF in three patients. After shunting, six patients(50%) improved markedly and four(33%) slightly. Overall outcome was good recovery in three, moderate disability in three, severe disability in three, vegetative state in two, and death in one patient. Several prognostic factors such as Glasgow Coma Scale value on admission, CT findings, intracranial pressure, interval from injury to the shunt, degree of cortical atrophy, and surgical method are not related to the result of the shunt(p>0.1 by Fisher's test). Since there are no accurate predictors for the result of shunt at present, one can not be sure that the patient with negative prognostic factors will not improve. Shunting rather than simple observation could be a suitable therapeutic trial especially for the bedridden patients.
Atrophy ; Glasgow Coma Scale ; Hemorrhage ; Humans ; Hydrocephalus* ; Intracranial Pressure ; Persistent Vegetative State ; Retrospective Studies ; Spinal Puncture ; Subarachnoid Hemorrhage

No abstract available.
Humans ; Infant, Newborn* ; Mass Screening*