1.A Case of Autoimmune Hemolytic Anemia Caused by Warm Antibody.
Sei Hee CHOI ; Mee Kyung NAMGOONG ; Baek Keun LIM
Journal of the Korean Pediatric Society 1986;29(8):86-89
No abstract available.
Anemia, Hemolytic, Autoimmune*
2.A Case of Acute Renal Failure Associated with Rhabdomyolysis in Carbon Monoxide Intoxication.
Kyung Hee PARK ; Sei Hee HWANG ; Hae Il CHEONG ; Yong CHOI ; Kwang Wook KO
Journal of the Korean Pediatric Society 1990;33(5):690-694
No abstract available.
Acute Kidney Injury*
;
Carbon Monoxide*
;
Carbon*
;
Rhabdomyolysis*
3.A Case of Preleukemia Presenting as Aplastic Anemia.
Dong Hee OH ; Sei Hee CHOI ; Baek Keun LIM ; Jong Soo KIM
Journal of the Korean Pediatric Society 1985;28(11):1141-1146
No abstract available.
Anemia, Aplastic*
;
Preleukemia*
4.Cord Plasma Alpha-Fetoprotein Values and Neonatal Jaundice.
Mee Kyung NAMGOONG ; Sei Hee CHOI ; Ae Sook KIM ; Baek Keun LIM ; Jong Soo KIM
Journal of the Korean Pediatric Society 1986;29(8):24-27
No abstract available.
alpha-Fetoproteins*
;
Infant, Newborn
;
Jaundice, Neonatal*
;
Plasma*
5.A study on the rapid development of ciprofloxacin resistane in methicillin-resistant staphylococcus aureus.
Chul Weon CHOI ; Hee Jin JUNG ; Heung Jung WOO ; Sei Yong KANG ; Woo Joo KIM ; Seung Chul PARK
Korean Journal of Medicine 1993;45(1):92-98
No abstract available.
Ciprofloxacin*
;
Methicillin Resistance*
;
Methicillin-Resistant Staphylococcus aureus*
6.Implementing and Evaluating a Nurse Led Hereditary Cancer Genetics Educational Program in a Korean Breast Cancer Surgery Clinic.
Kyung Sook CHOI ; Myung Hee JUN ; Sei Hyun AHN ; Gwen ANDERSON
Journal of Korean Academy of Adult Nursing 2008;20(6):815-828
PURPOSE: This study was to develop and evaluate the clinical utility of the breast and ovarian cancer genetic counselling program specific for 20 Korean women(KBOCGP). METHODS: The KBOCGP was developed using three types of approaches: an ethnography among Korean women who underwent BRCA1/2 test, designing and implementing one week clinical genetic educational course for clinical cancer nurses, educational observation visits to three American cancer genetic counselling programs. And then pre-experimental design was implicated to evaluate the change of the women's knowledge about the hereditary breast and ovarian cancer and the level of the satisfaction with genetic counselling. RESULTS: The mean score of the knowledge has significantly increased from 7.45 +/- 3.86 to 11.55 +/- 2.21(t = 5.63, p < .001). The level of the satisfaction with the counselling was very high (27.47 +/- 1.35). Because most of the subjects have young kids, they showed strong concerns about their kids' getting cancer. CONCLUSION: This new KBOCGP is the satisfactory program for the education and communication of the genetic information to the Korean women with HBOC. But it is needed more to strengthen the cultural sensitivity especially to Korean family relationships. Authors recommend that this program be provided by other nurses who are counselling women at high risk of breast cancer.
Anthropology, Cultural
;
Breast
;
Breast Neoplasms
;
Family Relations
;
Female
;
Genetic Counseling
;
Genetic Diseases, Inborn
;
Humans
;
Ovarian Neoplasms
;
Personal Satisfaction
7.Pinopode Development 2-days after Oocyte Retrieval in the Human IVF Patients.
Kyung Ah LEE ; Sei Yul HAN ; Dong Hee CHOI ; Woo Sik LEE ; Tae Ki YOON ; Kwang Yul CHA
Korean Journal of Fertility and Sterility 1998;25(1):51-58
INTRODUCTION There are three factors for successful implantation. These are embryo quality, uterine receptivity, and synchronization between embryonic and endometrial development. Despite remarkable progress in investigating embryos in human IVF, there has been slow progress in exploring the implantation process. It may be due to two reasons as follow. First, it is difficult to directly investigate the mechanism of implantation in the human, because of ethical considerations. Second, there is no sensitive and widely accepted marker for assessing endometrial development. Since the finding of a novel standard for dating endometrial biopsy by Noyes et. al.,. in 1950, there have been many attempts to identify suitable markers for uterine receptivity. Those include ultrasonographic changes (Ueno et.al., 1991; Grunfeld et al.,1991), three dimensional morphological changes of the endometrium such as pinopode formation (Market or alphaf., 1987; Mantel or alphaf., 1991; Nikas et al., 1995; Psychoyos & Nikas, 1994), integrin expression (Ilesanmi et al., 1993; Lessey et.al., 1992; Lessey, 1994), and measurement of endometrial proteins (Hell, 1986;Fay & Crudzinskas, 1991). Investigations in the rat (cartel et al., 1991)and human (cartel et al., 1987; Nikas et al., 1995; Psychoyos & Nikas, 1994) suggested the presence of pinopodes as a marker for the receptive phase.4 chronological barrier in uterine receptivity could be one of the major factors limiting IVF pregnancy rates. If we were able to manage the 'implantation window' we may be able to improve implantation and pregnancy rates in the human IVF program. In 1987, Martel et al., found early appearance of pinopodes in stimulated cycles for IVF compared to natural cycles in humans (Marcel et al., 1987). This effect was found in patients stimulated with clomephene citrate/hMG/hCG. The purpose of the present study was to evaluate the endometrial development in IVF patients stimulated with either by FSH/hMG/hCG or with GnRH agonist down regulation.
Animals
;
Biopsy
;
Down-Regulation
;
Embryonic Structures
;
Endometrium
;
Female
;
Gonadotropin-Releasing Hormone
;
Humans*
;
Oocyte Retrieval*
;
Oocytes*
;
Pregnancy Rate
;
Rats
8.Serum Insulin, Proinsulin and Proinsulin/Insulin Ratio in Type 2 Diabetic Patients: As an Index of beta-Cell Function or Insulin Resistance.
Nan Hee KIM ; Dong Lim KIM ; Kyung Mook CHOI ; Sei Hyun BAIK ; Dong Seop CHOI
The Korean Journal of Internal Medicine 2000;15(3):195-201
BACKGROUND: Although insulin resistance and decreased insulin secretion are characteristics of established type 2 DM, which of these metabolic abnormalities is the primary determinant of type 2 DM is controversial. It is also not well known how insulin resistance and beta cell dysfunction influence serum insulin, proinsulin, proinsulin/insulin ratio in type 2 DM. METHODS: We compared serum insulin, proinsulin and proinsulin/insulin ratio in type 2 diabetic patients and control subjects. We also investigated the relationship between serum insulin, proinsulin and proinsulin/insulin ratio and several biochemical markers which represent insulin resistance or beta cell function. RESULTS: Insulin, proinsulin and proinsulin/insulin ratio were significantly higher in type 2 DM than control(p < 0.001). In diabetic patients, total insulin level was correlated with urinary albumin excretion rates(r = 0.224, p = 0.025) and body mass index(r = 0.269, p = 0.014). Proinsulin level was correlated with fasting C-peptide(r = 0.43, p = 0.002), postprandial 2 hour blood glucose(r = 0.213, p = 0.05) and triglyceride(r = 0.28, p = 0.022). Proinsulin/insulin ratio was positively correlated with fasting C-peptide(r = 0.236, p = 0.031), fasting blood glucose (r = 0.264, p = 0.015), postprandial 2 hour blood glucose(r = 0.277, p = 0.001) and triglyceride(r = 0.428, p < 0.001). In control subjects, insulin level was correlated with triglyceride(r = 0.366, p = 0.002). Proinsulin/insulin ratio was correlated with age(r = 0.241, p = 0.044). CONCLUSION: The serum levels of insulin and proinsulin seem to be associated with several markers of insulin resistance. Whereas proinsulin/insulin ratio might represent beta cell function rather than insulin resistance. But more studies are needed to clarify the mechanisms of elevated proinsulin/insulin ratio in type 2 DM.
Aged
;
Diabetes Mellitus, Non-Insulin-Dependent/etiology
;
Diabetes Mellitus, Non-Insulin-Dependent/blood*
;
Female
;
Human
;
Insulin/blood*
;
Insulin Resistance*
;
Islets of Langerhans/physiopathology*
;
Male
;
Middle Age
;
Proinsulin/blood*
;
Sulfonylurea Compounds/pharmacology
9.A case of Small Cell Carcinoma of the Gallbladder.
Gwan Soo KWAK ; Hee Jin CHANG ; Seong Heum PARK ; Sei Hyuk PARK ; Kyong Woo CHOI
Korean Journal of Hepato-Biliary-Pancreatic Surgery 1999;3(2):181-186
Small cell carcinoma of the gallbladder is a rare neoplasm with a high malignant potential, representing about 4% of all carcinomas in this organ. It predominantly develops in older women with cholelithiasis and deaths usually occur within a few months after the diagnosis. We report a case with a small cell carcinoma of the gallbladder with literature review. A case of 74-year-old woman with fever and abdominal pain for days was temporarily diagnosed as empyema of the gallbladder and received emergency cholecystostomy. 15 days later, she underwent cholecystectomy. Pathological examination of the gallbladder revealed small cell carcinoma. Of the immunohistochemical stains for neuroendocrine and other tumor markers, this tumor was positive for cytokeratin, NSE, lysozyme, gastrin,p53 and p16 and negative for CEA, chromogranin, synaptophysin, somatostatin, serotonin and ACTH. The small cell was partially originated from the common premobial cell with bidirectional differentiation. She died of cancer cachexia 2 months after initial operation.
Abdominal Pain
;
Adrenocorticotropic Hormone
;
Aged
;
Cachexia
;
Carcinoma, Small Cell*
;
Cholecystectomy
;
Cholecystostomy
;
Cholelithiasis
;
Coloring Agents
;
Diagnosis
;
Emergencies
;
Empyema
;
Female
;
Fever
;
Gallbladder*
;
Humans
;
Keratins
;
Muramidase
;
Neuroendocrine Tumors
;
Serotonin
;
Somatostatin
;
Synaptophysin
;
Biomarkers, Tumor
10.A Case of Anomalous Termination of the Common Bile Duct and the Pancreatic Duct into the Duodenal Bulb, Associated with Common Bile Duct Stones.
Hee Bok CHAE ; Seon Mee PARK ; Sei Jin YOUN ; Yong Mo YANG ; Jae Woon CHOI
Korean Journal of Gastrointestinal Endoscopy 1999;19(6):1011-1015
Usually, the papilla of Vater is located in the midportion or the distal half of the descending duodenum. Isolated cases of common bile duct termination in other sites, including the fourth portion of the duodenum, the pyloric ring, the duodenal bulb and the stomach, have been reported. A case is here in reported involving abdominal pain in the right upper quadrant area, in which an ERCP demonstrated an anomalous termination of the common bile duct and pancreatic duct into the duodenal bulb separately. This anomaly was associated with a bile duct dilatation and single common bile duct (CBD) stone. Trial of CBD stone removal during an ERCP failed. The patient's condition improved after a cholecystectomy and choledochojejunostomy.
Abdominal Pain
;
Bile Ducts
;
Cholangiopancreatography, Endoscopic Retrograde
;
Cholecystectomy
;
Choledochostomy
;
Common Bile Duct*
;
Dilatation
;
Duodenum
;
Pancreatic Ducts*
;
Stomach