1.Diagnostic value of computed tomography in pancreatic cancer
Jin Woo KIM ; Young Seok KIM ; Chang Yul HAN ; Pil Mun YU ; Kwan Seh LEE
Journal of the Korean Radiological Society 1986;22(4):552-558
This retrospective study was performed to assess CT scan findings of pancratic cancer and its ability todetermine resectability. CT scans of 41 patients, who were diagnosed to have pancreatic cancer on histological orclinical base, were reviewed. Most common findings were; focal pancreatic enlargement, diffuse pancreaticenlargement, loss of distinct contour, peripancretic fat obliteration, bile duct or pancreatic duct dilatation,vascular invasion, lymph node involvement, direct invasion of adjacent organs and distant metastasis.Resectability was assessed according to generally accepted CT findings such as small pancreatic mass lesion havingnormal lobulated contour of pancreas, no evidence of vascular invasion, no evidence lymph node involvement andfree of distant metastasis. With the criteria, 5 cases among 41 cases deemed to be resectable. However onoperation all cases were found unresectable indicating prediction of tumor resectability is difficult even withhelp of CT. Nonetheless CT would be very helpful in management of patients having pancreatic cancer since CT wouldshorten the diagnostic procedures of pancreatic cancer.
Bile Ducts
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Humans
;
Lymph Nodes
;
Neoplasm Metastasis
;
Pancreas
;
Pancreatic Ducts
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Pancreatic Neoplasms
;
Retrospective Studies
;
Tomography, X-Ray Computed
2.Clinical Trials of Lactose Free Soyprotein Formula for Infantile Diarrhea.
Seh Young CHANG ; Hyeon Soo PARK ; Keun Soo LEE
Journal of the Korean Pediatric Society 1982;25(1):58-65
We studied 60 hospitalized sick infants with diarrhea to determine the efficacy of lactose free, soy-milk formula(Isomil) on the recovery of diarrhea. 60 sick infants were divided into two groups; Group 1 is consisted of 30 infants who were given Isomil, Group 2 is also consisted of 30 infants who were given 1/2 milk formula during the recovery stage, respectively. There was no difference between the two groups in admission weight, age, duration of diarrhea, number of stools per day, degree of dehydration and serum Na concentration. Initial management of the dirrhea was by means of intravenous fluid therapy and approprate period of fasting to allow intestinal rest. At 2nd day or 3rd day, the patient was given at random lactose free formula or 1/2 milk formula when we started to observe the frequency and consistency of stool. In Group 1, 23 successes and 7 failures. In Group 2, 13 successes and 17 failures. This represented a significant success rate in group I (p<0.025). The data suggest that during the recovery phase of gastroenteritis in young infants, a lactose free, soy-protein formula(Isomil) has definite adventages than 1/2 milk formula.
Dehydration
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Diarrhea
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Diarrhea, Infantile*
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Fasting
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Fluid Therapy
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Gastroenteritis
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Humans
;
Infant
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Lactose*
;
Milk
3.Clinical Study on Typhoid Fever in Children.
Seh Young CHANG ; Sang Yun LEE ; Woo Gill LEE ; Chong Moo PARK
Journal of the Korean Pediatric Society 1981;24(6):559-566
We studied clinically 109 caseu of typhoid fever in children, who were hospitalized in the Department of Pediatrics, Hanyang University Hospital for 5 years from January 1975 to December 1979. The results are as follows: 1) There were no specific differences have been noted in the annual incidence. 2) The highest incidence was noted in the summer season, which comprised of more than half of the total number of cases(52.3%) In whole of year, however, 11.9 percent noted in the winter Season. 3) The incidence of the disease was more in males are as compared to females, the respective percentage being 67 and 33. 4) The highest incidence was in the age group of 5~10 years, in percentage of 52.3. 5) The duration from onset to admission within 1 week were 55cases(50.5%), and from 1 week to 2 weeks were 33 cases(30.3%). The majority of cases admitted within 2 weeks. 6) The chief complaints on admission were fever(95%), abdominal pain(51%), anorexia (31%), nausea and vomiting(26%), and headache(25%). On physical examination, fever(95%), hepatomegaly(77%), injected throat(61%), bradycardia(27%), abdominal tenderness(18%), splenomegaly(21%) were noted. There was no rose spot. 7) The laboratory findings were as follow: Leukopenia was noted about Ilpercent, anemia was noted about 22 percent, however, no cases of Hgb level less than 8gm% was noted. In bacteriologic cultures, there were 35. 690 in blood culture and 6.6% in stool culture. There was no positive case in urine culture. In Widal test, there was 76.8% of positive result in 112 test cases. The percentage of positive cases were increased according to the duration of illness. 8) Complicated or associated diseases were 11% of total cases, in which majority were hepatitis and pneumonia. 9) In sensitivity test to antibiotics against organism isolated from blood culture, the most sensitive antibiotics was carbenicillin, followed by chloramphenicol, streptomycin, and ampicillin, Concerning annual variation of sensitivity to chloramphenicol and ampicillin, the sensitivity to chloramphenicol was no annual variation noted, but the sensitivity to ampicillin was decreased from the year of 1976.
Ampicillin
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Anemia
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Anorexia
;
Anti-Bacterial Agents
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Carbenicillin
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Child*
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Chloramphenicol
;
Female
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Hepatitis
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Humans
;
Incidence
;
Leukopenia
;
Male
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Nausea
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Pediatrics
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Physical Examination
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Pneumonia
;
Seasons
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Streptomycin
;
Typhoid Fever*
4.Factors Associated with Clinical Response to Low-Dose Dexamethasone Therapy for Bronchopulmonary Dysplasia in Very Low Birth Weight Infants
Jeongmin SHIN ; Seh Hyun KIM ; Young Hwa JUNG ; Chang Won CHOI ; Beyong Il KIM
Neonatal Medicine 2020;27(2):73-81
Purpose:
To identify factors associated with the clinical response to low-dose dexamethasone therapy (LDDT) in preterm infants for bronchopulmonary dysplasia (BPD).
Methods:
We used a retrospective medical record review to evaluate preterm infants who were born before 32 weeks of gestation or with a birth weight less than 1,500 g. All infants were admitted to the neonatal intensive care unit at a tertiary academic hospital between January 2010 and June 2019, and received LDDT for BPD. The preterm infants’ respiratory severity scores (RSS) were calculated from the first day of LDDT to the day of extubation, or the last day of LDDT. A good response was defined as a decreasing RSS with a slope greater than 0.181. A poor response was defined as a non-decreasing RSS, or a decreasing RSS with a slope less than 0.181 during LDDT. A total dose of 1.1 mg/kg was administered for 10 days for each single course of LDDT.
Results:
A total of 51 preterm infants were included in the final analysis. Thirty preterm infants (58.8 %) were in the good response group, and 21 preterm infants (41.2%) were in the poor response group. There were no significant differences in gestational age, birth weight, and sex between the good response group and poor response group. Preterm premature rupture of membrane and histologic chorioamnionitis were significantly associated with a poor response to LDDT. Higher RSS on the first day of the LDDT was associated with a good response to LDDT.
Conclusion
Antenatal infection and/or inflammation may be associated with an unfavorable response to postnatal LDDT for BPD. Preterm infants with more severe respiratory failure seem to benefit more from LDDT for BPD.
5.Preoperative Diagnosis of Strangulated Obturator Hernia Using CT.
Seh Jin CHANG ; Chul Hee LEE ; Seung Hye CHOI ; Ji Young YUN ; Chang Hyeok AHN ; Nam Il KIM ; Seong LEE ; Seung Jin YOO ; Keun Woo LIM
Journal of the Korean Surgical Society 2001;61(2):216-219
Obturator hernia is a rare pelvic hernia, occuring most frequently in elderly, debilitated women. Because of nonspecific symptoms, the diagnosis of obturator hernia is often delayed until laparotomy for bowel obstruction. This leads to high bowel resection and mortality rates, which represents a diagnostic and therapeutic challenge for surgeons today. We experienced an unusual case of right obturator hernia with strangulation in an 81-year-old female patient who presented with intermittent generalized, particularly right lower quadrant, abdominal pain and distension. The hernia was diagnosed by computed tomography (CT) scan and repaired using the lower midline transperitoneal approach. CT scan in the evaluation of patients with nonspecific intermittent gastrointestinal symptoms leads to a diagnosis of occult hernia. We report these findings with a brief review of the literature focusing on finding indicators leading to early diagnosis and treatment.
Abdominal Pain
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Aged
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Aged, 80 and over
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Diagnosis*
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Early Diagnosis
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Female
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Hernia
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Hernia, Obturator*
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Humans
;
Ileus
;
Laparotomy
;
Mortality
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Tomography, X-Ray Computed