No abstract available.

Authors observed one case of subcutaneous dermoid cyst which did not seem to have been described in the Korean literature. A 11 year old female patient complained of a asymptomatic mass near the left sternoclavicular joint in January 1978. The mass was discovered at the age of 5 when that was pea-sized and had been slowly growing. In January 1978, the mass was palpable as a peanut-sized subcutaneous solitary round mass, and overlying skin was freely movable and slightly elevated. There was no trauma history and family history was negative except her elder sister had a, axillary accessory breast. Histopathologic studies revealed a keratinizing stratified squamous epithelium lining the cystic wall, and sebaceous glands, hair follicle and eccrine glands in the surrounding tissues, and keratinous materials in the cyst. There was no evidence of malignancy. Diagnosis was confirmed by clinical features and histopathological findings, and surgical excision of tumor mass was performed.
Breast ; Child ; Dermoid Cyst* ; Diagnosis ; Eccrine Glands ; Epithelium ; Female ; Hair Follicle ; Humans ; Sebaceous Glands ; Siblings ; Skin ; Sternoclavicular Joint

Improvement of lichen planus was achieved by 11 weeks of daily oral treatment with griseofulvin. The patient was 59-year-old male, has had hypertension and diabetes mellitus for 9 months, and history of various drug intake to these diseses for 6 months. Four months before first visit, symptome of lichen planus had developed suddenly. Because of treatment failure of oral antihistamine and topical steroid for 6 weeks, we began to use griseofulvin. Praspective studies are needed to better assess the affectiveness of griseafulvin in the treatment of lichen planus.
Diabetes Mellitus ; Griseofulvin* ; Humans ; Hypertension ; Lichen Planus* ; Lichens* ; Male ; Middle Aged ; Treatment Failure

We present a case of familial benign chronic pemphigus in 50-year-old male patient who had had recurrent oozing, macerated and eroded skin lesions on the groin and scrotum for 20 years. At first, we diagnosed his case as scrotal eczema and/or intertrigo, but after repeated recurrance, it was confirmed as above disease by characteristic histopathologic findings.
Cytochrome P-450 CYP1A1 ; Eczema ; Groin ; Humans ; Intertrigo ; Male ; Middle Aged ; Pemphigus, Benign Familial* ; Scrotum ; Skin

We present a case of generalized syringoma in a 12-year-old healthy girl. The patient has numerous skin colored or yellowish papules on the face, neck, anterior chest, axillae and abdomen. She has a family history of eyelid syringoma occuring in her mother and maternal grandmother. Diagnosis was confirmed by characteristic histopathologic findings.
Abdomen ; Axilla ; Child ; Diagnosis ; Eyelids ; Female ; Humans ; Mothers ; Neck ; Skin ; Syringoma* ; Thorax

Dermatologist should be aware of the practical importance of proper selection of ski.n lesions for histologic examination, the correct methods for performing biopsy, and steps involved in tissue preparation. They should be acquainted with factors producing various artifacts and ways to prevent these changes. This study was undertaken to investigate the artifacts of 300 dermatopathologic tissue sections which prepared by 3 general hospitals in Seoul in 1983. The results were summarized as follows. [.The percentage of artifacts produced by selection of inapropriate lesion was 4. 0% artifacts during biopsy procedure was 18. 3% inadequate size and depth of specimen was 7. 3%, faulty embedding was 12. 0%, tissue tearing or loss was 49. 3% artifactal dermoepidermal separation was 3.0%, linear knife marking was 17.0% thick or thin section was 8. 3% tissue overlapping was 12. 0% uneven stiining or precipitation was 3. 7%, and foreign body contamination was 3, 7% The percentage of good specimen was 21, 7% diagnostic was 56. 3% not diagnostic but suggestive was 8.7% and reading impossible was 13. 3% 3. The major causes of reading impossible specimen which attributed to the procedures of dermatologist were 40.0% to the proccss of technician were 47.5% and to both were 12. 5%
Artifacts* ; Biopsy* ; Foreign Bodies ; Hospitals, General ; Seoul ; Skin*

Although we made a comparision of fingertip dermatoglyphic patterns between R7 patients with atopic dermatitis(Femals: 54, Male: 35) and 73 their families without atopic dermatitis, no significant results were obtained. So, we compared secondly our results of 2 groups with those of two thousand nonatopic, normal Koreans, as control. Results are as follows: ] In comparison with control, a significant increase in the ulnar loop pattern was detected in families(p<0, ()5), not atopic dermatitis. p. No significant differ ence between right hands and left hands in all three g f OUpS. In atopic dermatitis and control groups, 1 st and 4 th digits showed mostly whorl pattern, and 3 rd and 5 th digits had more ulnar loop pattern than others. Rut families had mostly ulnar loop pattern at all digits except 4 th digit, wl..orl pattern. 4. Each of atopic dermatitis, family and control group had 13, 79% (whor1: 8. 05% ulnar loop: 5 75%), 15. 49p; (whorl: 4. 23%, ulnar loop: 11. 27%), 15. 78%(whorl: 8, 52% ulnar loop: 7. 1 %, arch: 0. 05%), of same dermatoglyphic pattern on all ten digits. Especially, ulnar loop pattern in fanilies was detected significantly higher than other two groups(p<0. 05). Average incidences of bilateral symmetry of pattern type between right and left digits were 78.57%, 74. 67% and 78.74% respectively in atopic dermatitis, family and control group.
Dermatitis, Atopic* ; Dermatoglyphics* ; Hand ; Humans ; Incidence ; Male

Vitiligo is an acquired, disfiguring skin disease characterized by the loss of melanin, which results in depigmented areas of the skin. It affects at least 1% of the world's population. In countries where people are dark skinned, vitiligo is a major health problem. The pathogenesis of vitiligo has not been fully elucidated, but three possible origins, autoimmune, neurohumoral and self destruction of melanocyte, have been described. The clinical manifestations of vitiligo are well described in many reports. However in Korea, a few studies on the clinical features of vitiligo have been performed. Authors studied 217 Korean cases of vitiligo who had been visited at the Department of Dermatology, Kyung Hee University Hospital during the last 1 year (1978.4.1~1979.3.31). (countinued..)
Dermatology ; Korea ; Melanins ; Melanocytes ; Skin ; Skin Diseases ; Vitiligo*

We report one case of hair follicle nevus, benign highly differentiating appendageal skin tumor of hair follicle. It arises from pluripotential cells that have formed during life. This patient is a 40-year-old woman who had a localized brownish plaque on the leht cheek for three years. Histologic study revealed many small but mostly mature hair follicles consistent with hair follicle nevus.A Case of Cutaneous Periarteritis Nodosa
Adult ; Cheek ; Female ; Hair Follicle* ; Hair* ; Humans ; Nevus* ; Polyarteritis Nodosa ; Skin

A 25-year-old female was seen because of rnultiple, asymptornatic papular eruptions on the vulvar area since 1 year ago. She had been suffered from palmar hyperhidrosis for 3 years. A skin biopsy specimen from the vulval lesion revealed characteristic findings of syringoma.
Adult ; Biopsy ; Female ; Humans ; Hyperhidrosis ; Skin ; Syringoma*