No abstract available.
Humans* ; Sebum*

Omphalith generally consists of keratinous materials and sebum. It gradually forms a stone-like hard, dark brown to a black mass in elderly persons with deep umbilical depression and not clean umbilicus. A 75 years old male noticed a brownish black nodule on the umbilical depression 2 weeks ago. He did not try to remove it. This nodule gradually became to project from umbilical depression accompanied with intermittent pain. Removed specimen was brownish black stonelike on projecting polypoid lesion, but in umbilical depression, yellowish brown and not so hard. Histopathological examination showed a small quantity of melanin granules, but no nuclear components of cells.
Aged ; Depression ; Humans ; Male ; Melanins ; Sebum ; Umbilicus

BACKGROUND: An increasing number of methods have been developed to determine skin properties in an objective way. Variable atmospheric conditions or climatic changes influence the physiological reaction process occurring in skin. Clinical studies investigating skin conditions are often performed through different seasonal environments. Therefore, physiological stabilization course in a standard environment is necessary to exclude climatic influence before measuring skin physiological parameters. OBJECTIVE: The purpose of this study was to investigate stabilization course of several skin physiological parameters after exposure to summer and winter conditions. METHODS: Fifteen healthy volunteers (9 males, 6 females) with normal skin, of age 20 to 35 (mean 25.3) years were included in the study. After 30 minutes exposure to summer or winter climatic conditions, the volunteers stayed in the standard environment for 30 minutes. Skin surface temperature, skin color, transepidermal water loss (TEWL) and sebum were measured every 10 minutes in the standard room. RESULTS: Skin surface temperature stabilized after 20 minutes on forehead and 30 minutes on cheek irrespective of the season. Skin color (L*, a*, b*) stabilized after 20 minutes in standard environment irrespective of the season and location of measurement. TEWL stabilized after 10 minutes and sebum stabilized after 20 minutes in standard environment irrespective of the season and location of measurement. CONCLUSION: To obtain stabilized values of skin surface temperature, skin color, TEWL and sebum irrespective of season and measurement location, 30 minutes of stabilization course is needed.
Cheek ; Forehead ; Humans ; Male ; Seasons ; Sebum ; Skin ; Skin Temperature

BACKGROUND: Glycolic acid and Jessner's solution have been popular agents for superficial chemical peeling to treat facial acne. Increased sebum secretion is one of the major etiological factors of acne. There has been no report to compare effects on sebum secretion in patients with facial acne between glycolic acid peeling and Jessner's solution peeling. OBJECTIVE: We compared the effects on sebum secretion in patients with facial acne after glycolic acid peeling or Jessner's solution peeling. METHODS: Twenty patients with facial acne vulgaris were studied. Eight patients were treated with 30% glycolic acid peeling and twelve patients with Jessner's solution peeling. Before and 2 weeks after the treatment, the sebum levels of forehead, nose, center of chin and both cheeks were measured by using Sebumeter(R). RESULTS: The sebum levels were not significantly changed after 30% glycolic acid peeling. After Jessner's solution peeling, the total average, and average of T-zone of sebum levels, were reduced significantly (p<0.05). The high-sebum-level area was defined as the area where the sebum level before treatment was high. The average of sebum levels of the high-sebum-level area was reduced significantly (p<0.01). CONCLUSION: 30% glycolic acid peeling did not affect sebum secretion, but Jessner's solution peeling reduced sebum secretion in patients with facial acne significantly, especially on the areas where sebum secretion was high.
Acne Vulgaris* ; Cheek ; Chin ; Forehead ; Humans ; Nose ; Sebum*

BACKGROUND: In the last few decades, there has been a substantial increase in the population of aged people. Aging skin is a common concern for many people these days. OBJECTIVE: The purpose of this study was to evaluate the efficacy of cosmetics containing Ascidian tunic in reducing wrinkles. METHODS: Cream containing the Ascidian tunic was applied to right lateral epicanthal areas of 30 subjects for 8 weeks. As control group, a placebo which does not contain the Ascidian tunic was applied to the left lateral epicanthal areas of the subjects. Skin barrier function was evaluated and skin replicas were molded on both epicanthal areas every 4 weeks. The changes of the skin wrinkles were analyzed with skin visiometer. RESULTS: In comparison of the changes between groups treated with placebo and Ascidian tunic, there was statistically significant differences in hydration and sebum secretion. But there were no statistically significant differences in the result of R-value by visiometer. CONCLUSION: The treatment of Ascidian tunic extract seems to be partially effective in improving wrinkles, but further study is required.
Aged ; Aging ; Cosmetics ; Fungi ; Humans ; Sebum ; Skin ; Urochordata

BACKGROUND: Although sebum secretion is crucial for acne development, acne lesion distribution is not always similar to the topographic differences of sebum secretion. OBJECTIVE: To analyze whether sebum secretion affects acne development and distribution and to assess other factors possibly influencing the relationship between acne and sebum secretion. METHODS: This single-center retrospective study included 67 acne patients and 50 controls. Acne patients were divided into 3 groups based on acne lesion distribution: T-zone dominant, U-zone dominant, and mixed groups. The secreted sebum level in each zone of acne patients was compared with that of controls. We also conducted correlation analysis between secreted sebum level and acne number, depending on the facial zone. RESULTS: No significant difference was found between acne patients and controls regarding age and sex ratio. The U-zone dominant group showed increased sebum levels compared with controls in the U-zone and whole face, but a similar result was not obtained in the T-zone dominant group. Moreover, there was a significant correlation between the number of lesions and secreted sebum level in the U-zone, but not in the T-zone. Further, there was a more significant relation in the U-zone of male and young patients. CONCLUSION: We found that increased sebum secretion compared with the condition may affect acne development, especially in the U-zone. Sex and age may also influence the relationship between acne and increased sebum secretion. Acne lesion distribution may vary from patient to patient because sebum secretion affects acne differently depending on multiple factors.
Acne Vulgaris ; Humans ; Male ; Retrospective Studies ; Sebum ; Sex Ratio

Acne vulgaris is an inflammatory disease of hair follicle sebaceous gland units,with an incidence of up to 85% in adolescents.The pathogenesis is closely related to androgen,sebum secretion,lipophilic microbial infection,and immune-inflammatory reaction.This article reviews the signaling pathways related to acne from the aspects of inflammatory signaling pathways and sebum secretion pathways.
Acne Vulgaris ; Adolescent ; Humans ; Sebaceous Glands ; Sebum ; Signal Transduction

BACKGROUND: Enlarged skin pore is a type of serious cosmetic defect for many women. However, the mechanisms underlying the skin pores remain unclear. Currently, several treatment methods are in practice for enlarged skin pores and the most common among those are topical alpha-hydroxy acid, retinoid and chemical peel. OBJECTIVE: To evaluate the patients' knowledge, awareness and method of the treatment of the skin pores. METHODS: Analysis of the interview results and questionnaire responses from 256 individuals, who did not having any history of medical disease. RESULTS: The number of patients who think that they have enlarged skin pores was 225 (88%). The most common site was around the nose (48%). Enlarged skin pores are thought to be caused by several factors; seborrhea (38%), after removal of sebum (35%) and acne (30%), and common dissatisfactions with enlarged skin pores were visible blackheads and older looks. Patients receive skin care for enlarged skin pores via various remedies, but only 11% actually received dermatologic procedure. CONCLUSION: High proportion of the population has great concerns regarding their enlarged skin pores, but lack proper treatment. Enlarged skin pores lead to one's dissatisfaction, such as blackheads and older look. Thus, we should investigate the insight on skin pores and offer beneficial treatments for concerned patients.
Acne Vulgaris ; Cosmetics ; Dermatitis, Seborrheic ; Female ; Humans ; Nose ; Sebum ; Skin ; Skin Care ; Surveys and Questionnaires

The authors describe a case of large dermoid cyst of the scalp which removed surgically and cosmetically. Dermoid cyst is derived from epiblastic cells predestined to form skin which become detached from their neighbours and included in mesenchyme at about third to the fifth week of feral life, when the neural tube is closing. The contents of the cyst are thus mixtures of keratin, sebum, and hair, according to the proportionate development of these elements. It is usually a single tumor and may develop almost anywhere in the subcutaneous tissue, being of variable size.
Dermoid Cyst* ; Germ Layers ; Hair ; Mesoderm ; Neural Tube ; Scalp ; Sebum ; Skin ; Subcutaneous Tissue

BACKGROUND: Acne vulgaris is a common dermatologic disease that can largely affect psychosocial aspects of the patient. OBJECTIVE: This study was performed to survey the perception of acne vulgaris, including the cause of acne vulgaris, and patient attitude towards the disease, as well as preference for treatment methods in Busan. METHODS: A total of 170 patients with acne vulgaris, seeking treatment at 1st-, 2nd-, and 3rd-grade hospitals in Busan, were surveyed by questionnaire. Patient informed consent was obtained. RESULTS: With regards to the cause of acne, increased sebum secretion was the most selected answer, followed by stress and eating habits. Most of the patients believed that all of the acne treatment modalities were effective; however, negative recognition about the safety and durability of each treatment was also reported by a majority of the patients. Acne extraction and laser therapy were the most preferred treatment methods, and the most important reason to choose the treatment method was effectiveness. CONCLUSION: In this study, we could recognize a patients' overall perception about acne vulgaris. It is suggested that dermatologists should try not only to help patients gain a better understanding about acne but also to cope with their demands.
Acne Vulgaris* ; Busan ; Eating ; Humans ; Informed Consent ; Laser Therapy ; Sebum ; Surveys and Questionnaires