Background: This study compared and analyzed various concentrations of mesoporous bioactive glass (MBG) gel, commercialacidulated phosphate fluoride gel (APF-gel), and Tooth MousseTM (TM) to evaluate the enamel remineralization effect of early dental caries. Methods: The samples prepared using sound bovine teeth were subjected to MBG gel, APF-gel, and TM to measure changes insurface hardness (Vickers hardness number, VHN) and fluorescence loss values compared to those of sound teeth (ΔF).Repeated measures analysis of variance (ANOVA), Friedman’s ANOVA, Wilcoxon signed-rank test, one-way ANOVA, and Kruskal-Wallis test were used for statistical analysis. Results: The VHN was significantly increased after the two treatments compared to the initial VHN in all other groups, with theexception of the APF gel group (p＜0.05). Compared to the initial ΔF, the APF-gel group significantly decreased ΔF after two treatments, and the remaining groups exhibited significantly increased ΔF (p＜0.05). The MBG group exhibited significantly higher ΔF values than those of the APF gel and TM groups (p＜0.05). Conclusion The MBG group exerted a significantly higher remineralization effect than that of the APF gel group and exhibited asimilar or slightly higher remineralization effect compared to that of the TM group.

Background: This study compared and analyzed various concentrations of mesoporous bioactive glass (MBG) gel, commercialacidulated phosphate fluoride gel (APF-gel), and Tooth MousseTM (TM) to evaluate the enamel remineralization effect of early dental caries. Methods: The samples prepared using sound bovine teeth were subjected to MBG gel, APF-gel, and TM to measure changes insurface hardness (Vickers hardness number, VHN) and fluorescence loss values compared to those of sound teeth (ΔF).Repeated measures analysis of variance (ANOVA), Friedman’s ANOVA, Wilcoxon signed-rank test, one-way ANOVA, and Kruskal-Wallis test were used for statistical analysis. Results: The VHN was significantly increased after the two treatments compared to the initial VHN in all other groups, with theexception of the APF gel group (p＜0.05). Compared to the initial ΔF, the APF-gel group significantly decreased ΔF after two treatments, and the remaining groups exhibited significantly increased ΔF (p＜0.05). The MBG group exhibited significantly higher ΔF values than those of the APF gel and TM groups (p＜0.05). Conclusion The MBG group exerted a significantly higher remineralization effect than that of the APF gel group and exhibited asimilar or slightly higher remineralization effect compared to that of the TM group.

Background: This study compared and analyzed various concentrations of mesoporous bioactive glass (MBG) gel, commercialacidulated phosphate fluoride gel (APF-gel), and Tooth MousseTM (TM) to evaluate the enamel remineralization effect of early dental caries. Methods: The samples prepared using sound bovine teeth were subjected to MBG gel, APF-gel, and TM to measure changes insurface hardness (Vickers hardness number, VHN) and fluorescence loss values compared to those of sound teeth (ΔF).Repeated measures analysis of variance (ANOVA), Friedman’s ANOVA, Wilcoxon signed-rank test, one-way ANOVA, and Kruskal-Wallis test were used for statistical analysis. Results: The VHN was significantly increased after the two treatments compared to the initial VHN in all other groups, with theexception of the APF gel group (p＜0.05). Compared to the initial ΔF, the APF-gel group significantly decreased ΔF after two treatments, and the remaining groups exhibited significantly increased ΔF (p＜0.05). The MBG group exhibited significantly higher ΔF values than those of the APF gel and TM groups (p＜0.05). Conclusion The MBG group exerted a significantly higher remineralization effect than that of the APF gel group and exhibited asimilar or slightly higher remineralization effect compared to that of the TM group.

Recently with the development in computer technology and its communication system, many changes have come to the medical field. For example, Picture Archiving and Communication System(PACS) has been used in the medicine experimentally. But this system needs high cost and instrument, so this system is not used in personal generally. Our hospital established the medical forum for health and medical counseling in Computer communication network called HITEL. We analysed the questions about urologic problem especially from Sep, 1994 to Jan, 1997. Most of questions are related to external genitalia and sexually transmitted diseases and most of users were in their 2nd, 3rd and 4th decades and male-predominant. In conclusion, medical counseling using PC communication is an effective method especially in urologic field.
Computer Communication Networks ; Counseling* ; Genitalia ; Humans ; Microcomputers ; Sexually Transmitted Diseases

No abstract available.
Animals ; Epithelium* ; Gene Expression* ; Laser Capture Microdissection* ; Mice* ; Microarray Analysis* ; Phenobarbital*

Current therapeutic approaches for presbyphonia are generally categorized into non-invasive and surgical methods. Voice therapy is commonly chosen as initial treatment modality used to reduce maladaptive compensatory muscle behavior and to improve glottal closure. Nevertheless, in advanced cases of presbyphonia, glottal insufficiency may be aggravated, reducing the benefits of voice therapy. To manage the glottal insufficiency observed in such cases, surgical intervention is performed to medialize the vocal folds. Available surgical modalities include injection laryngoplasty and type I thyroplasty. Additionally, cutting-edge regenerative treatments, such as the injection of basic fibroblast growth factor, are under investigation internationally and show promising outcomes. This review aims to elucidate the current indications and relevance of surgical interventions for presbylarynx.

PURPOSE: Craniospinal neurenteric (NE) cysts are rare developmental non-neoplastic cysts of the central nervous system with diverse MR imaging findings. The purpose of this study was to evaluate various MR imaging findings of intracranial and intraspinal NE cysts. MATERIALS AND METHODS: We retrospectively reviewed the MR imaging findings of six NE cysts that were confirmed by pathology. We evaluated anatomic location, signal intensity, size and enhancement pattern of NE cysts. RESULTS: Two intracranial lesions were located extra-axially in the cerebellopontine angle and quadrigeminal cisterns. Three spinal lesions were intraduralextramedullary cysts, located ventral to the spinal cord, but one thoracic lesion was an intramedullary cyst. The signal intensity of the cysts was hyperintense on T1-weighted images as compared with the cerebrospinal fluid (CSF) for two intracranial lesions and one cervical lesion. In addition, all intracranial lesions showed diffusion restriction. For the remaining three spinal lesions, the signal intensity was nearly the same as the signal intensity of the CSF as seen on both T1- and T2-weighted images. On contrast-enhanced studies, two intracranial cysts showed a small nodular enhancement and one thoracic spinal lesion showed rim enhancement. CONCLUSION: NE cysts have various locations, signal intensities, and possible focal nodular or rim enhancement. Therefore, NE cysts can be included in the differential diagnosis of various craniospinal cystic or tumorous cystic lesions.
Central Nervous System ; Cerebellopontine Angle ; Diagnosis, Differential ; Diffusion ; Neural Tube Defects ; Retrospective Studies ; Spinal Cord

OBJECTIVE: This study is to report our experience of 40 cases of spinal schwannoma. METHODS: From 1995 to 2006, medical records were retrospectively reviewed in 40 cases of spinal schwannoma. RESULTS:We treated 40 spinal schwannomas in 38 (22 male and 16 female) patients. The mean age was 50.2. Four cases were sited in the cervical spine, 11 cases in the thoracic spine, and 25 cases in the lumbar spine. Two patients showed recurrences. Thirty-eight cases were intradural-extramedullary type and 2 cases were extradural. Two cases (5%) including 1 recurred case had no postoperative motor improvement. Ninety-five percents of patients improved on postoperative motor grade. CONCLUSION: Spinal schwannoma is mostly benign and extramedullary tumor. There were 2 recurred cases (5%) that had history of previous subtotal removal at first operation and had shown worse prognosis compared with the cases without recurrence. To reduce the recurrence of spinal schannoma, total excision of tumor mass should be done.
Humans ; Male ; Medical Records ; Neurilemmoma ; Prognosis ; Recurrence ; Retrospective Studies ; Spine

BACKGROUND/AIMS: Liver biopsy has been used to evaluate the degree of hepatic fibrosis in patients with chronic liver diseases. It is important to assess liver fibrosis when following the course of chronic liver diseases. Histopathological examination of percutaneous biopsy specimens is invasive and is also of questionable value because of the heterogenous distribution of pathological changes in the liver. Therefore, non-nvasive methods to determine the progress of liver fibrosis are needed. Serum hyaluronic acid and type IV collagen are known to be related to hepatic fibrosis. This study was performed to evaluate the clinical usefulness of serum hyaluronic acid and type IV collagen measurement as a differential point in patients with chronic liver diseases and early cirrhosis. METHODS: This study included 109 patients with chronic liver diseases caused by various etiologies. Liver biopsy and histopathological classification were done in all patients. Serum hyaluronic acid and type IV collagen were measured by one-tep sandwich binding protein assay and one-tep sandwich enzyme immunoassay. RESULTS: The concentrations of hyaluronic acid and type IV collagen in the early cirrhosis group (208.5+/-186.4 ng/mL, 242.1+/-162.8 ng/mL) were significantly higher (p<0.01) than those in the normal and fatty liver group (26.3+/-21.7 ng/mL, 79.2+/-28.8 ng/mL), mild chronic hepatitis group (22.8+/-15.4 ng/mL, 125.5+/-79.7 ng/mL), moderate to severe hepatitis group (66.3+/-60.5 ng/mL, 148.5+/-78.7 ng/mL). At the cutoff value of 100 ng/mL for hyaluronic acid and 200 ng/mL for type IV collagen, the sensitivities were 66.7% and 55.6%, and specifities were 82.9% and 89%, and diagnostic efficiencies were 78.9% and 80.7% respectively for discriminating patients with cirrhosis (4 points) from the mild to severe fibrosis (0~3 points). CONCLUSIONS: The serum levels of hyaluronic acid and type IV collagen may be sensitive markers of fibrotic process in chronic liver diseases and useful biochemical markers in differentiation of the patients with early cirrhosis from those with chronic liver diseases.
Biomarkers ; Biopsy ; Carrier Proteins ; Classification ; Collagen Type IV* ; Fatty Liver ; Fibrosis ; Hepatitis ; Hepatitis, Chronic* ; Humans ; Hyaluronic Acid* ; Immunoenzyme Techniques ; Liver Cirrhosis* ; Liver Diseases ; Liver*

A 28-year-old primigravida at 33 weeks gestation was referred to our hospital because of aggravation of seizures which occurred intermittently for the past 2 years. A brain magnetic resonance imaging scan taken at 33 weeks gestation showed a large brain tumor (7X5X4 cm) in the left high frontal lobe. She had a cesarean section under general anesthesia at 38 weeks and 1 day gestation. General anesthesia was induced with thiopental 250 mg, succinylcholine 75 mg and lidocaine 60 mg after a vecuronium 0.8 mg intravenous injection. The hyperventilation and mannitol used to reduce increased intracranial pressure (ICP) in this patient may be harmful and detrimental to the fetus before delivery. Achieving both ICP control and fetal well being at the same time during a cesarean section can be challenging to anesthesiologists. We report the anesthetic management of a cesarean section in a patient with a large brain tumor.
Adult ; Anesthesia, General* ; Brain Neoplasms* ; Brain* ; Cesarean Section* ; Female ; Fetus ; Frontal Lobe ; Humans ; Hyperventilation ; Injections, Intravenous ; Intracranial Pressure ; Lidocaine ; Magnetic Resonance Imaging ; Mannitol ; Pregnancy ; Seizures ; Succinylcholine ; Thiopental ; Vecuronium Bromide