No abstract available.
Nicotine*

The aim of this study was to examine the effect of phase I cardiac rehabilitation program (CRP) on physical capacity in patients with coronary artery bypass graft (CABG). Eighty seven patients who underwent CABG in our hospital were enrolled on the study. Among them, excluding 17 during the study, the results of 70 patients were included in the final data. Subjects were classified into two groups according to the participation in the phase I CRP; participation group (n=35) and non-participation group (n=35). The CR was executed for the participation group until patients' discharge. The variables including resting heart rate (RHR), oxygen saturation, walking distance in 6 minutes, and forced expiration amount were measured at initial phase, discharge and follow-up at 1 month after discharge. From the data, descriptive statistics (mean, standard deviation) were calculated, and differences in each variable before, during, after the treatment and between groups were tested using repeated measure analysis of variance using SPSS ver. 18.0 statistics program for Window. For the effects and results with a statistical significance, post-hoc test was made using t-test. There was statistically significant difference (p<0.05) in the RHR and the walking distance in 6 minutes. While there was no significant difference in the oxygen saturation and the maximum expiration amount. As conclusion, the Phase I CRP after CABG showed a effect on the significant improvement of physical capacity by decreasing the RHR and increasing the walking distance in 6 minutes, exerting a positive influence on the recovery after the CABG operation.
Coronary Artery Bypass ; Coronary Vessels ; Follow-Up Studies ; Heart ; Heart Rate ; Humans ; Oxygen ; Transplants ; Walking

In spite of many available antibiotics and chemotherapeutics, genitourinary tract infection still remains as troublesome subject for urologist. Since we always interested in the effects and side effects of the new antibacterial agent in urinary infection, we administered indanyl carbenicillin 3-4 gm for 2-20 days to 58 cases of various urinary infections, patients for the preparation of surgical and endoscopic operation and for the prevention of septicemia after endoscopy. The results were obtained as follower 1) Among 3 cases of gonorrheal urethritis, 2 cease were cured rapidly and one case was improved. 2) Among 34 cases of chronic non-gonorrheal urethritis, 19 cases were cured and 9 cases were improved. 3) Among 4 cases of chronic prostatitis, one case was improved. 4) Among 5 cases of pyelonephritis. 4 cases were cured and one case was improved. 5) Among 12 patients who underwent soundation, endoscopy and T.U.R., postoperative infections were not found in 11 cases. 6) In 10 out of 34 cases of chronic non-gonorrheal urethritis, daily doses of 4 gm of indanyl carbenicillin were given orally for 12 days, and observation was done on the changes of clinical symptoms, urinalysis, hematology, blood urea nitrogen and liver function test before, during and after treatment. Excellent results were obtained in all 10 cases with only slight side effects such as indigestion, gastric soreness, nausea and abdominal distension.
Anti-Bacterial Agents ; Blood Urea Nitrogen ; Carbenicillin* ; Dyspepsia ; Endoscopy ; Hematology ; Humans ; Liver Function Tests ; Nausea ; Prostatitis ; Pyelonephritis ; Sepsis ; Urethritis ; Urinalysis ; Urinary Tract Infections* ; Urinary Tract*

We are reporting 7 cases of ureteral polyps associated with upper urinary stones. All of the 7 patients were male, ranging from 28 to 42 years of-age and the average was 36 years. Flank pain was complained in all cases but palpable mass was not noted. Microscopic hematuria was noted in 5 cases. The duration of symptoms ranged from 6 months to 10 years. The polyps were found on the right ureter in 2 cases and on the left ureter in 6 cases. The polyps were located at upper third ureter in 5 cases, at middle third in 2 cases and at lower third in 1 case. Excretory urogram and retrograde pyelogram revealed filling defects due to polyps in 2 cases and hydronephrosis or hydroureter proximal to the stones in all cases. Chronic inflammatory ureteral polyps were diagnosed histologically in all 7 patients. This investigation suggests that polyps are likely to develop in the cases of upper urinary stones which stays in one spot for a long duration.
Flank Pain ; Hematuria ; Humans ; Hydronephrosis ; Male ; Polyps* ; Ureter* ; Urinary Calculi*

No Abstract Available.
Lower Extremity* ; Varicose Veins*

An effect of D-phenylalanine on the pain inhibitory mechanism of prolonged electrical stimulation of the peripheral nerve was studied in decerebrate cats and spinal cats. The response of spinal neurons was elicited either by electrical stimulation of the ipsilateral common peroneal nerve and tibial nerve. The single-unit activity of motor neurons which represent the flexion reflex was recorded from a filament of ventral rootlet divided from either the L7, S1 or S2 ventral root, and activity of dorsal horns cells was recorded with a microelectrode at the lumbosacral cord The conditioning stimuli which provocate the pain inhibitory mechanism of the common peroneal or tibial nerve was applied with repetitive, low frequency (2Hz), at a suprathreshold intensity for C fiber, for 30-45 minutes. The results of the experiment are summarized as follows: 1. Applying conditioning stimuli produced a powerful inhibition of the responses which was provocated by noxious stimuli in either the decerebrate or the spinal cat without any statistical difference, and this effect can be observed for 15 minutes after the cessation of the conditioning stlmuli 2. This response was reversed completely by systemic injection of a specific opiate antagonist, naloxone. It suggests that the conditioning stimulus of the peripheral nerve can produce the endogenous opiate related pain inhibitory effect as the spinal mechanism. 3. The conditioning stimuli can produce the analgesic effect by means of supression of the activity of the dorsal horn cell which was related to the pain response in the decerebrate cat. The same result could be observed in flexion reflex. 4. D-phenylalanine, a putative inhibitor of carboxypeptidase which degradates the endogenous opiate-enkephalin, was studied in this experiment under the hypothesis that D-phenylalanine will emphasize or prolongate the action of enkephalin. But, intravenously injected D-phenylalanine did not potentiate the inhibitory effect of the conditioning stimuli of the peripheral nerve. From the above result, it is speculated that the electrical stimulation of the peripheral nerve is directly mediated by an endogenous opiate related analgesia, and the site of the analgesic action resides mainly in spinal cord level. But these data could not support the gypothesis that antinociceptive effect of D-phenylalanine results frm the potentiation of endogenously released enkephalin.
Analgesia* ; Animals ; Cats* ; Electric Stimulation ; Enkephalins ; Horns ; Microelectrodes ; Motor Neurons ; Naloxone ; Nerve Fibers, Unmyelinated ; Neurons ; Peripheral Nerves* ; Peroneal Nerve ; Posterior Horn Cells ; Reflex ; Spinal Cord ; Spinal Nerve Roots ; Tibial Nerve

Hemorrhagic metastatic brain tumors of hepatocellular carcinoma (HCC) are rare and have been mostly presented as intracranial hemorrhage (ICH). A 51-year-old male patient presented with sudden altered level of consciousness. He suffered from HCC since 2010 and transarterial chemoembolization was performed three times for HCC. The brain computed tomography (CT) scans revealed subdural hematoma (SDH) in the right fronto-temporal area and 6.0x3.5 cm sized ICH in the right parieto-occipital lobe. Brain angiographic CT scans demonstrated that the hemorrhagic lesions did not include any enhancing lesions and vascular abnormalities. We undertook a decompressive craniectomy and evacuation of the acute SDH and ICH. During evacuation of ICH, the yellowish mass was observed in the cortical surface of the right occipital lobe. Pathological examination displayed the findings of metastatic brain tumor from HCC. Metastatic brain tumors should be considered in the differential diagnosis as a cause of spontaneous SDH with ICH.
Brain Neoplasms ; Brain* ; Carcinoma, Hepatocellular* ; Cerebral Hemorrhage* ; Consciousness Disorders ; Decompressive Craniectomy ; Diagnosis, Differential ; Hematoma, Subdural* ; Humans ; Intracranial Hemorrhages ; Male ; Middle Aged ; Neoplasm Metastasis* ; Occipital Lobe ; Tomography, X-Ray Computed

Meningioma is a common primary tumor of central nervous system. However, extracranial extension of the intracranial meningioma is unusual, and mostly accompanied the osteolytic change of the skull. We herein describe an atypical meningioma having extracranial extension with hyperostotic change of the skull. The patient was a 72-year-old woman who presented a large mass in the right frontal scalp and left hemiparesis. Brain magnetic resonance imaging and computed tomography scans revealed an intracranial mass, diffuse meningeal thickening, hyperostotic change of the skull with focal extension into the right frontal scalp. She underwent total removal of extracranial tumor, bifrontal craniectomy, and partial removal of intracranial tumor followed by cranioplasty. Tumor pathology was confirmed as atypical meningioma, and she received adjuvant radiotherapy. In this report, we present and discuss a meningioma en plaque of atypical histopathology having an extracranial extension with diffuse intracranial growth and hyperostotic change of the skull.
Aged ; Brain ; Central Nervous System ; Female ; Humans ; Magnetic Resonance Imaging ; Meningioma* ; Osteoblasts* ; Paresis ; Pathology ; Radiotherapy, Adjuvant ; Scalp ; Skull*

OBJECTIVE: Placement of a ventriculoperitoneal (VP) shunt is a common neurosurgical procedure for cerebrospinal fluid diversion. A rare complication is delayed intracranial hemorrhage (ICH) secondary to VP shunting, and only a few patients with this complication have been reported. We investigate the incidence and risk factors of delayed ICH development following VP shunt placement. METHODS: Over an 11-year period, 167 patients received a VP shunt for hydrocephalus, and of these, 138 patients were eligible for this study. All medical records and computed tomography scans obtained within 48 h after the operation and at postoperative day 7 were reviewed. The risk factors of developing delayed ICH (≥48 hr after VP shunt placement) were analyzed according to the demographic data, including sex and age, original intracranial lesions, co-morbid diseases, and laboratory findings. RESULTS: Delayed ICH following VP shunt placement developed in 34 (24.6%) of the 138 patients. Risk factors for developing delayed ICH were age (p=0.037) and the partial thromboplastin time (PTT) (p=0.032). Intraventricular hemorrhage after VP shunting was the most common complication, occurring in 16 cases. Hemorrhagic volume was < 1 mL in 28 cases and >1 mL in 6 cases. CONCLUSION: This study suggests that old age and delayed PTT are major risk factors for developing delayed ICH following VP shunting. Additionally, delayed ICH after VP shunting commonly occurs even when most patients are asymptomatic. Therefore, extra care should be taken to observe and follow-up with patients who have undergone VP shunt placement.
Cerebrospinal Fluid ; Follow-Up Studies ; Hemorrhage ; Humans ; Hydrocephalus ; Incidence ; Intracranial Hemorrhages* ; Medical Records ; Neurosurgical Procedures ; Partial Thromboplastin Time ; Risk Factors* ; Ventriculoperitoneal Shunt*

No abstract available.
Conus Snail* ; Hemangioblastoma*