One case of osteoid osteoma in the lamina of the fifth lumbar spine with hamstring muscle tightness was experienced and successfully treated by surgery at the department of orthopedic surgery in Seoul National University Hospital. Literature on the subject was reviewed in detail.
Muscle Tonus ; Orthopedics ; Osteoma, Osteoid ; Seoul ; Spine

Marfan Syndrome is a rare congenital disease characterized by the abnormalities of Sheletal system, eye and cardio-vascular system which was initially desiribed by Marfan in 1896. One case of marfan syndrome was treated at the department of Orthopedic Surgery, College of Medicine, Seoul National University for multiple skeletal deformities. Moderate degree of scoliosis was treated with Milwaukee brace and finger deformities with Z-plasty and full thickness skin graft.
Braces ; Congenital Abnormalities ; Fingers ; Marfan Syndrome ; Orthopedics ; Scoliosis ; Seoul ; Skin ; Transplants

Two hundreds cases of spine tuberculosis were treated surgically for the period of 7 years between 1970 and 1976 at Seoul National University Hospital and following results were obtained. 1. Many patients failed to be treated with conservative method. Spontaneous fusion was found in 10% of 200 cases with long duration of disease. Anterior fusion was performed in 166 cases and posterior fusion was carried out in 34 cases. In those 34 cases, anterior currettage was combined in 7 cases, anterior fusion combined in 19 cases in which 7 cases were performed anterior and posterior fusion at one stage. Posterior fusion alone was carried out only in 8 cases. 2. Anterior fusion is indicated for: a. decompression in cord involvement b. confirmation of diagnosis c. involvement of one joint space in children d. mild to moderate kyphosis in adult 3. Anterior and posterior fusion is indicated in: a. severe kyphosis for solid funsion b. involvement of more than two joint spaces in children to prevent increasing kyphosis c. one stage operation was technically possible and has many advantages 4. Posterior fusion is indicated in: a. poor general condition b. technically difficult cases.
Adult ; Child ; Decompression ; Diagnosis ; Humans ; Joints ; Kyphosis ; Methods ; Seoul ; Spine ; Tuberculosis

We assessed the accuracy of Goldmann or Schi-(phi)tz tonometric readings in the gas filled vitrectomized eyes. We performed pars plana vitrectomy with or without lensectomy in 8 rabbit eyes, and in 6 enucleated porcine eyes. Fluid-air exchange was done at the end of the procedure. Intraocular pressure was measured using Goldmann tonometer and Schi-(phi)tz tonometer and was compared with true pressure which was monitored by manometer with indwelling catheter in the intravitreal cavity. Goldmann and Schi-(phi)tz tonometry always showed lower presure value than manometeric one(P<0.05) and the discrepancy was greater at higher range of intraocular pressure. Between these two methods Goldmann tonometry was more accurate in the rabbit eye (P>0.05).
Catheters, Indwelling ; Intraocular Pressure* ; Manometry ; Reading ; Vitrectomy

The short time antibacterial effect of tetracaine hydrochloride was studied. S. aureus, Coagulase Negative Staphylococcus and P. aeruginosa were each incubated with tetracaine hydrochloride(preservative free) for 18 hours or for 2 minutes and then diluted and cultured on nutrient agar plate. Colony counts were done after 18 hours. In cases of 18 hours incubation, there was no growth of microbials in 0.5%, 0.1% tetracaine hydrochloride, but there was no inhibitory effect of 0.02% of tetracaine hydrochloride on growth of microbials, irrespective of inoculum amount. In cases of 2 minutes incubation with 0.5% tetracaine hydrochloride, there was no difference between the amount of microbial inoculum and colony count. Above in vitro study indicates that tetracaine hydrochloride has no inhibitory effect on bacterial growth in short time exposure less than 2 minutes.
Agar ; Coagulase ; Staphylococcus ; Tetracaine*

The short time antibacterial effect of tetracaine hydrochloride was studied. S. aureus, Coagulase Negative Staphylococcus and P. aeruginosa were each incubated with tetracaine hydrochloride(preservative free) for 18 hours or for 2 minutes and then diluted and cultured on nutrient agar plate. Colony counts were done after 18 hours. In cases of 18 hours incubation, there was no growth of microbials in 0.5%, 0.1% tetracaine hydrochloride, but there was no inhibitory effect of 0.02% of tetracaine hydrochloride on growth of microbials, irrespective of inoculum amount. In cases of 2 minutes incubation with 0.5% tetracaine hydrochloride, there was no difference between the amount of microbial inoculum and colony count. Above in vitro study indicates that tetracaine hydrochloride has no inhibitory effect on bacterial growth in short time exposure less than 2 minutes.
Agar ; Coagulase ; Staphylococcus ; Tetracaine*

Multifocal choroiditis and panuveitis(MCP) is a clinical syndrome characterized by vitritis, and punched-out fundus lesions mimicking presumed ocular histoplasmosis. We diagnosed MCP in a twenty-eight years old woman with the complaint of decreased vision and floater symptom. Retinochoroidal anastomosis via one of retinochoroidal scars was noted in this case. The patient was treated with oral and periocular steroid and ws observed for 11 months during which choroidal neovascularization and macular edema ws not developed. We present this case because, as far as our knowledge goes, There has been no reported case of MCP with retinochoroidal anastomosis.
Choroid* ; Choroidal Neovascularization ; Choroiditis* ; Cicatrix ; Female ; Histoplasmosis ; Humans ; Macular Edema ; Panuveitis*

PURPOSE: Prepapillary vascular loops are blood vessels that project from the optic disc into the vitreous cavity and then return to the disc to continue their natural cource. Ninety percent are arterial in origin and usually congenital anomaly. We report four cases of prepapillary vascular loops associated with retinal and choroidal disorders. METHODS: Prepapillary vascular channel which showed twisted or ringlike appearance without leakage on fluorescein angiogram constituted the diagnosis. However, there may be a sector delay in filling of the optic disc or retina supplied by the loop due to the increased distance that blood must travel through the loop. RESULTS: These cases are not associated with vision-threatening diseases. The associated retinal diseases are diabetic retinopathy in one case, retinitis pigmentosa in one case, contralateral posterior uveitis in two cases. They are arterial loops. In two eyes were observed multiple prepapillary vascular loops. The vessels may appear as simple hairpin loops, spiral, or corkscrew configuration. In our cases, the presence of a cilioretinal artery and retinal artery obstruction could not be determined; other complication associated with prepapillary vascular loops were not observed. CONCLUSIONS: We assume that prepapillary vascular loops may occur acquiredly associated with other ocular diseases.
Arteries ; Blood Vessels ; Choroid ; Diabetic Retinopathy ; Diagnosis ; Fluorescein ; Retina ; Retinal Artery ; Retinal Diseases* ; Retinaldehyde* ; Retinitis Pigmentosa ; Uveitis, Posterior

PURPOSE: To evaluate whether the degree of melanin pigmentation of fundus or intraocular pressure would have influence on the determination of laser power for effective transpupillary thermotherapy(TTT). METHODS: TTT was performed on 6 eyes of each of the brown, yellow and white rabbits. Immediately after diode laser irradiation to posterior pole, retinal periphery, and iris with various power(2 mm, 60 or 120 sec), macular threshold power(MTP), peripheral threshold power(PTP), and iris threshold power(ITP) were defined as a maximum power not causing any ophthalmoscopic change on the respective laser site. To assess the influence of intraocular pressure, TTT was performed with the eyeballs compressed as much as retinal arterial pulsation disppeared. Three weeks after laser irradiation, funduscopic and fluorescein angiographic appearance were correlated with histopathologic findings. RESULTS: We found no difference of MTP between brown and yellow rabbit but their MTP were smaller than that of white one(P<0.05). There was positive correlation between MTP, PTP and ITP in all experimental species. ITP/MTP and PTP/MTP were 3.45+/-0.68, 1.09+/-0.10 in brown rabbit, 3.84+/-0.79, 1.12+/-0.13 in yellow rabbit and 4.13+/-0.43, 1.16+/-0.14 in white rabbit respectively. When TTT was performed with the eyeball compressed, the laser spot looks whiter in all cases than without. Microscopic examination revealed occlusion of choriocapillaris and photoreceptor degeneration in the laser spots formed by MTP. CONCLUSION: When performing TTT, one should reduce the laser power according to the amount of melanin pigmentation of fundus and intraocular pressure. Empirical laser burn to the retinal periphery will be a helpful mean to determine optimal laser power for TTT.
Burns ; Choroidal Neovascularization ; Fluorescein ; Hyperthermia, Induced* ; Intraocular Pressure ; Iris ; Lasers, Semiconductor ; Melanins ; Pigmentation ; Rabbits ; Retinaldehyde

Massive subretinal hemorrhage may develop secondary to choroidal neovascularization. The poor visual prognosis associated with submacular hemorrhage can be explained by preexisting abnormality of photoreceptorretinal pigment epithelium-Bruch's membrane complex and fibrin-mediated injury to the outer segment of photoreceptor. An animal experiment showed that subretinal fibrin induced irreversible damage to the retina within 24 hours. We use recombinant tissue plasminogen activator(rt-PA), at doses(3 microgram substantially lower than previously reported, to aid in the surgical evacuation of massive subretinal hemorrhage within 2 days of its development. The subretinal hemorrhage in both patients developed in association with age-related macular degeneration. Postoperative corrected visual acuity improved from counting fingers to 0.3 in one patient and from hand motion to 0.04 in the other. There has been no complication except ocular hypertension which is medically controllable. Subfoveal neovascularization explains poor postoperative vision in one case. It seems that visual recovery is facilitated by early evacuation of massive subretinal hemorrhage and by using low-dose rt-PA. Low-dose rt-PA may minimize the risks of intraocular hemorrhage and retinal toxicity.
Animal Experimentation ; Choroidal Neovascularization ; Fibrin ; Fingers ; Hand ; Hemorrhage* ; Humans ; Macular Degeneration ; Membranes ; Ocular Hypertension ; Plasminogen ; Prognosis ; Retina ; Retinaldehyde ; Tissue Plasminogen Activator* ; Visual Acuity