1.Suprascapular nerve entrapment syndrome by a ganglion, treated with nonoperative method: a case report.
Sang Hoon LEE ; Jin Woo KWON ; Choong Gil LEE ; Jae Hyum PARK ; Kwi Ryun KWON ; Woo Se LEE
The Journal of the Korean Orthopaedic Association 1997;32(3):731-734
Entrapment syndrome of suprascapular nerve by a ganglion has been reported not frequently. We experienced a case of suprascapular nerve entrapment by ganglion which was treated with non-operative treatment, and report it with literature.
Ganglion Cysts*
;
Nerve Compression Syndromes*
2.The Report of the Results of HPV Oligonucleotide Microarray Tested on the First Voided Urine of Patients of CIN and Cervix Cancer.
Eun Seop SONG ; Sun Hwan KOH ; Yun Seob SONG ; Se Ryun KIM ; Sung Ook HWANG ; Jee Hyun PARK ; Seung Kwon KOH ; Moon Whan IM ; Byoung Ick LEE ; Woo Young LEE
Korean Journal of Obstetrics and Gynecology 2003;46(11):2139-2145
OBJECTIVE: To know whether HPV Oligonucleotide Microarray (HPVDNAChip) can detect the HPV DNA in the urine and, if it can, to compare the results with Pap smear, biopsy, and cervix HPVDNAChip. METHODS: The authors had done Pap smear, cervix HPVDNAChip and colposcopy-guided punch biopsy as well as detailed information to those who visited Dept. of Ob. And Gyn. during 1st of April to 31st of May in 2003 for their uterine cervical problems related to the neoplasia. When they were determined to admit for treatment, urine had been collected to be tested by HPVDNAChip. RESULTS: Among 25 patients enrolled in this study, there were 10 whose urine HPVDNAChip test turned out positive (40%). Among 10 positive results, 9 patients had HPV 16 subtypes. Among 10 urine HPVDNAChip positive patients, there were 5 HSIL, 4 squamous cell cancer (SCC), and 1 ASCUS cell types on the Pap smears. Among 15 urine HPVDNAChip negative patients, there were 7 HSIL, 5 SCC, 1 ASCUS, 1 LSIL, and 1 AGUS. Among 10 urine HPVDNAChip there are 5 CIN3, and 4 invasive SCC, and 1 adenocarcinoma at the biopsy. Among 15 urine HPVDNAChip negative patients, there are 7 CIN3, 6 invasive SCC, 1 adenocarcinoma in situ, and 1 CIN1 patient. Whenever there were a urine HPVDNAChip 16 subtype positive, there were always cervix HPVDNAChip 16 subtype positive, but among the 12 urine HPVDNAChip negative patients, 5 had HPV 16 subtype positive and 4 had another subtypes and 3 had negative on cervix HPVDNAChip tests. CONCLUSION: Using HPVDNAChip, we verified that 40% of patients had the HPV DNA in their urine who had admitted for the treatment of their cervical neoplasm. And HPV 16 subtype was the most common type in the urine. If we can extend this data more widely, we might use it as an auxiliary tool for cervical HPV infection.
Adenocarcinoma
;
Biopsy
;
Cervix Uteri*
;
DNA
;
Female
;
Human papillomavirus 16
;
Humans
;
Neoplasms, Squamous Cell
;
Oligonucleotide Array Sequence Analysis*
;
Uterine Cervical Neoplasms*
3.Clinical Significance of HPV DNA test for Management of Patients with Diagnosis of Atypical Squamous Cells of Undetermined Significance/Low-grade Squamous Intraepithelial Lesions.
Jeong Rye LEE ; Song Eun SEOP ; Heong Hun LEE ; Se Ryun KIM ; Jee Hyun PARK ; Sung Ook HWANG ; Seung Kwon KOH ; Moon Whan IM ; Byoung Ick LEE
Korean Journal of Obstetrics and Gynecology 2003;46(2):268-275
OBJECTIVE: This study was performed to evaluate the clinical efficacy of high risk HPV DNA test using PCR for the detection of high-grade CIN or invasive cancer from patients with ASCUS or LSIL on Papanicolaou smear. METHODS: Sixty one patients with a Papanicolaou smear report of atypical squamous cells of undetermined significance or a low-grade squamous intraepithelial lesion underwent Cervical colposcopy and directed cervical biopsy and human papillomavirus test by PCR. We compared the detection rate of the high grade CIN and invasive cancer by Papanicolaou smear method only with that of both Papanicolaou smear and HPV PCR method. and we decided to be significant when P value was below 0.05 by SAS (v 6.02) program. RESULTS: The detection rate of high risk HPV DNA was 50.8% (31/61). The detection rate of high risk HPV DNA in high grade CIN and invasive cancer was 84.2% (16/19). Higher the grade of biopsy, more the detection rate of high risk HPV DNA. False negative rate which appeared high grade CIN or invasive cancer by biopsy was 31.2% (19/61) in Papanicolaou smear method only and 4.9% (3/61) in both Papanicolaou smear and HPV DNA method. CONCLUSION: We thought that additional HPV DNA test was useful to dectect behind high grade CIN or invasive cancer when the Papanicolaou smear result was ASCUS or LSIL.
Biopsy
;
Colposcopy
;
Diagnosis*
;
DNA
;
Human Papillomavirus DNA Tests*
;
Humans
;
Papanicolaou Test
;
Polymerase Chain Reaction
4.First Report of Clavinema mariae (Nematoda: Philometridae) in Cultured Rockfish, Sebastes schlegeli, in Cheonsuman (Bay), the Republic of Korea.
Hyun Ja HAN ; Jung Soo SEO ; Jeong Su PARK ; Haeng Lim LEE ; Han Gill SEO ; Sung Hee JUNG ; Se Ryun KWON
The Korean Journal of Parasitology 2017;55(2):219-224
In July 2012, philometrid nematodes were discovered in cultured rockfish (Sebastes schlegeli) in Cheonsuman (Bay), the Republic of Korea. The nematodes were detected in the epithelial tissues of the rockfish and were identified as Clavinema mariae based on morphological studies using light and scanning electron microscopy. They revealed the characteristics same as previously identified C. mariae, notably having a long body with narrow posterior half, no caudal projection, a cylindrical-shaped esophagus, a well-developed anterior bulbous part of the esophagus, cephalic papillae, and a dorsal esophageal gland. This is the first confirmation of C. mariae infection in rockfish in Korea.
Esophagus
;
Korea
;
Microscopy, Electron, Scanning
;
Republic of Korea*
5.A Case of Peripartum Cardiomyopathy Associated Preeclampsia.
Jee Hyun PARK ; Eun Seop SONG ; Se Ryun KIM ; Sung Ook HWANG ; Seung Kwon KOH ; Moon Whan IM ; Byoung Ick LEE ; Woo Young LEE
Korean Journal of Obstetrics and Gynecology 2003;46(12):2560-2564
Peripartum cardiomyopathy is an uncommon form of dilated cardiomyopathy that is often fatal to young women. Estimates of the incidence vary from 1 in 1,300 to 1 in 15,000 pregnancies. The diagnostic criteria of peripartum cardiomyopathy are onset of cardiac failure in the latter part of pregnancy or in the puerperium, absence of obvious cause for cardiac failure and absence of demonstrable heart disease before the last trimester of pregnancy. The delayed diagnosis of this disease may be common due to the rarity of this condition. The early diagnosis and medical treatment for this disease is critical because it may affect the patient's long term prognosis. The mortality rate has been reported to be ranged from 25% to 50%. Persistence of disease after 6 months indicates irreversible cardiomyopathy and portends worse survival. The recurrence of peripartum cardiomyopathy in subsequent pregnancy remains high. The clinical presentation and treatment of patients with peripartum cardiomyopathy are similar to those of patients with congestive heart failure. We experienced a case of this disease in 25 year-old woman who had preeclampsia and preterm labor at 33 weeks of gestation. And report this case with a brief review of the literatures.
Adult
;
Cardiomyopathies*
;
Cardiomyopathy, Dilated
;
Delayed Diagnosis
;
Early Diagnosis
;
Female
;
Heart Diseases
;
Heart Failure
;
Humans
;
Incidence
;
Mortality
;
Obstetric Labor, Premature
;
Peripartum Period*
;
Postpartum Period
;
Pre-Eclampsia*
;
Pregnancy
;
Pregnancy Trimester, Third
;
Prognosis
;
Recurrence
6.Clinical Significance of HPV DNA Chip Test in the Management of Atypical Squamous Cells of Undetermined Significance.
Soo Bin YIM ; Eun Seop SONG ; Dong Hyun LEE ; Se Ryun KIM ; Jee Hyun PARK ; Sung Ook HWANG ; Seung Kwon KOH ; Moon Hwan LIM ; Byoung Ick LEE ; Woo Young LEE
Korean Journal of Obstetrics and Gynecology 2003;46(12):2451-2457
OBJECTIVE: Cervical intraepithelial neoplasia (CIN) and invasive cervix cancer were detected in some cases of atypical squamous cells of undetermined significance (ASCUS) PAP smear. So it is reasonable to evaluate and manage ASCUS PAP smear. In this study, we attempted to assess the clinical significance of a cytologic diagnosis of ASCUS and determine the usefulness of HPV DNA chip test (which is a new diagnostic method for HPV) in management and evaluation of ASCUS patients. METHODS: This study was performed from November 2001 to June 2002 and included 48 cases of ASCUS. They were evaluated by HPV DNA chip test and the pathology was evaluated by punch biopsy, cone biopsy or hysterectomy. The result of type 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68 and 69 in HPV DNA chip test were categorized as high risk. RESULTS: The rate of CIN II or above in ASCUS was 18.8% (9/48). The detection rate of high risk HPV DNA in ASCUS was 41.7% (20/48). The detection rate of high risk HPV DNA was 30.6% (11/36) in normal or reactive, 33.3% (1/3) in CIN I, 80% (4/5) in CIN II, 100% (2/2) in CIN III, 100% (2/2) in invasive cervix cancer. Higher the grade of pathology, more the detection rate of high risk HPV DNA chip test. The sensitivity for the prediction of CIN II or above by HPV DNA chip test was 88.9% and specificity was 69.2%, respectively. CONCLUSION: The use of HPV DNA chip test in patients with ASCUS may provide usefulness in detection of CIN II, CIN III and invasive cervix cancer.
Biopsy
;
Cervical Intraepithelial Neoplasia
;
Diagnosis
;
DNA*
;
Humans
;
Hysterectomy
;
Oligonucleotide Array Sequence Analysis*
;
Pathology
;
Sensitivity and Specificity
;
Uterine Cervical Neoplasms