1.Settling time of dental x-ray tube head after positioning.
Suk Ja YOON ; Byung Cheol KANG ; Se Myung WANG ; Chang Sung KOH
Korean Journal of Oral and Maxillofacial Radiology 2002;32(3):159-165
PURPOSE: The aim of this study was to introduce a method of obtaining the oscillation graphs of the dental x-ray tube heads relative to time using an accelerometer. MATERIALS AND METHODS: An Accelerometer, Piezotron type 8704B25 (Kistler Instrument Co., Amherst, NY, USA) was utilized to measure the horizontal oscillation of the x-ray tube head immediately after positioning the tube head for an intraoral radiograph. The signal from the sensor was transferred to a dynamic signal analyzer, which displayed the magnitude of the acceleration on the Y-axis and time lapse on the X-axis. The horizontal oscillation of the tube head was measured relative to time, and the settling time was also determined on the basis of the acceleration graphs for 6 wall type, 5 floor-fixed type, and 4 mobile type dental x-ray machines. RESULTS: The oscillation graphs showed that tube head movement decreased rapidly over time. The settling time varied with x-ray machine types. Wall-type x-ray machines had a settling time of up to 6 seconds, 5 seconds for fixed floor-types, and 11 seconds for the mobile-types. CONCLUSION: Using an accelerometer, we obtained the oscillation graphs of the dental x-ray tube head relative to time. The oscillation graph with time can guide the operator to decide upon the optimum exposure moment after xray tube head positioning for better radiographic resolution.
Acceleration
;
Head Movements
;
Head*
;
Radiography
2.Settling time of dental x-ray tube head after positioning.
Suk Ja YOON ; Byung Cheol KANG ; Se Myung WANG ; Chang Sung KOH
Korean Journal of Oral and Maxillofacial Radiology 2002;32(3):159-165
PURPOSE: The aim of this study was to introduce a method of obtaining the oscillation graphs of the dental x-ray tube heads relative to time using an accelerometer. MATERIALS AND METHODS: An Accelerometer, Piezotron type 8704B25 (Kistler Instrument Co., Amherst, NY, USA) was utilized to measure the horizontal oscillation of the x-ray tube head immediately after positioning the tube head for an intraoral radiograph. The signal from the sensor was transferred to a dynamic signal analyzer, which displayed the magnitude of the acceleration on the Y-axis and time lapse on the X-axis. The horizontal oscillation of the tube head was measured relative to time, and the settling time was also determined on the basis of the acceleration graphs for 6 wall type, 5 floor-fixed type, and 4 mobile type dental x-ray machines. RESULTS: The oscillation graphs showed that tube head movement decreased rapidly over time. The settling time varied with x-ray machine types. Wall-type x-ray machines had a settling time of up to 6 seconds, 5 seconds for fixed floor-types, and 11 seconds for the mobile-types. CONCLUSION: Using an accelerometer, we obtained the oscillation graphs of the dental x-ray tube head relative to time. The oscillation graph with time can guide the operator to decide upon the optimum exposure moment after xray tube head positioning for better radiographic resolution.
Acceleration
;
Head Movements
;
Head*
;
Radiography
3.The Korean Medication Algorithm Project for Depressive Disorder 2021: Comparisons with Other Treatment Guidelines
Young Sup WOO ; Won-Myong BAHK ; Jeong Seok SEO ; Young-Min PARK ; Won KIM ; Jong-Hyun JEONG ; Se-Hoon SHIM ; Jung Goo LEE ; Seung-Ho JANG ; Chan-Mo YANG ; Sheng-Min WANG ; Myung Hun JUNG ; Hyung Mo SUNG ; Il Han CHOO ; Bo-Hyun YOON ; Sang-Yeol LEE ; Duk-In JON ; Kyung Joon MIN
Clinical Psychopharmacology and Neuroscience 2022;20(1):37-50
The Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) first was published in 2002, and has been revised four times, in 2006, 2012, 2017, and 2021. In this review, we compared recommendations from the recently revised KMAP-DD 2021 to four global clinical practice guidelines (CPGs) for depression published after 2010. The recommendations from the KMAP-DD 2021 were similar to those from other CPGs, although there were some differences. The KMAP-DD 2021 reflected social culture and the healthcare system in Korea and recent evidence about pharmacotherapy for depression, as did other recently published evidence-based guidelines. Despite some intrinsic limitations as an expert consensus-based guideline, the KMAP-DD 2021 can be helpful for Korean psychiatrists making decisions in clinical settings by complementing previously published evidence-based guidelines, especially for some clinical situations lacking evidence from rigorously designed clinical trials.
4.Korean Medication Algorithm Project for Depressive Disorder 2021 (III): Child and Adolescent
Chan-Mo YANG ; Se-Hoon SHIM ; Won-Myong BAHK ; Young Sup WOO ; Jong-Hyun JEONG ; Sheng-Min WANG ; Won KIM ; Jeong Seok SEO ; Jung Goo LEE ; Young-Min PARK ; Seung-Ho JANG ; Myung Hun JUNG ; Hyung Mo SUNG ; IL Han CHOO ; Bo-Hyun YOON ; Sang-Yeol LEE ; Duk-In JON ; Kyung Joon MIN
Journal of Korean Neuropsychiatric Association 2021;60(3):193-203
Objectives:
The Korean Medication Algorithm Project for Depressive Disorder 2021 (KMAP-DD 2021) was a revision of previous works. The main purpose of the current study was to amend guidelines for the treatment of a major depressive disorder (MDD) for children and adolescents.
Methods:
The survey consisted of 21 questionnaires for children and adolescents. A total of 33 of the 46 experts in child and adolescent psychiatry answered the survey.
Results:
Antidepressant (AD) monotherapy was selected as the 1st line option for MDD with mild to moderate severity. As the 1st line of treatment for MDD severe without psychotic features in children and adolescents, AD monotherapy and AD augmented with atypical antipsychotics (AAP) were recommended. For MDD with psychotic features, AD augmented with AAP was preferred as the 1st line of treatment.
Conclusion
We developed an algorithm for child and adolescent populations with depressive disorders, more specifically than the KMAP-DD 2017. We expect this algorithm will provide clinicians useful information and help in the treatment of children and adolescents with depressive disorders.
5.Korean Medication Algorithm Project for Depressive Disorder 2021 (II): The Subtypes of Depression
Young-Min PARK ; Jeong Seok SEO ; Young Sup WOO ; Won-Myong BAHK ; Won KIM ; Jong-Hyun JEONG ; Se-Hoon SHIM ; Jung Goo LEE ; Seung-Ho JANG ; Sheng-Min WANG ; Myung Hun JUNG ; Hyung Mo SUNG ; L Han CHOO ; Bo-Hyun YOON ; Sang-Yeol LEE ; Duk-In JON ; Kyung Joon MIN
Journal of Korean Neuropsychiatric Association 2021;60(3):186-192
Objectives:
The Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) was developed in 2002 and revised in 2006, 2012, 2017. In 2021, the fifth edition was published.This edition reflected new findings and the latest trends in the areas of pharmacological treatment. The aim of this study is to present strategies and treatment options according to the subtype of depression using data from the KMAP-DD-2021.
Methods:
Ninety-seven psychiatrists with clinical experience in depressive disorder were selected. The questionnaires for KMAP-DD 2021 were sent to participants via mail. KMAP-DD 2021 consists of overall treatment strategies and treatment options under specific circumstances.Each treatment strategy or treatment option was evaluated with an overall score of nine and was divided into the three phases of recommendation that include primary, secondary, and tertiary.
Results:
For persisting depressive disorder, antidepressant monotherapy including selective serotonin reuptake inhibitor (SSRI) (escitalopram, fluoxetine, sertraline, paroxetine), serotoninnorepinephrine reuptake inhibitor (SNRI) (desvenlafaxine, venlafaxine, duloxetine, milnacipran), vortioxetine, and mirtazapine, was recommended as first-line medications. For melancholia of major depressive disorder, SSRI, SNRI, vortioxetine, and mirtazapine also were recommended as first-line medications. For mixed features, SSRI, bupropion, mirtazapine, SNRI, except for duloxetine, and milnacipran were recommended as first-line medications. For anxious distress, SSRI, mirtazapine, and SNRI, except milnacipran, were recommended as first-line medications.
Conclusion
The preferences of antidepressants by experts differed according to the subtype of depression. These findings suggest that experts treat patients with a major depressive disorder after considering the subtype of depression involved.
6.Korean Medication Algorithm Project for Depressive Disorder 2021 (I): Treatment Strategies for Major Depressive Episode
Young Sup WOO ; Won-Myong BAHK ; Jeong Seok SEO ; Young-Min PARK ; Won KIM ; Jong-Hyun JEONG ; Se-Hoon SHIM ; Jung Goo LEE ; Seung-Ho JANG ; Sheng-Min WANG ; Myung Hun JUNG ; Hyung Mo SUNG ; IL Han CHOO ; Bo-Hyun YOON ; Sang-Yeol LEE ; Duk-In JON ; Kyung Joon MIN
Journal of Korean Neuropsychiatric Association 2021;60(3):174-185
Objectives:
The Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) is a consensus-based medication guideline. To reflect advances in pharmacotherapy for depressive disorders, we have undertaken a fourth revision of the KMAP-DD.
Methods:
The review committee for the new version of the KMAP-DD (KMAP-DD 2021) included 143 Korean psychiatrists with clinical experience in the field of depressive disorders. Each treatment strategy or treatment option was evaluated with an overall score of nine, and the treatment option was categorized into the three levels of recommendation of primary, secondary, and tertiary.
Results:
The first-line pharmacotherapeutic strategy for mild to moderate major depressive episodes (MDE) was antidepressant (AD) monotherapy. For severe MDE without psychotic features, AD monotherapy or the combination of AD and atypical antipsychotics (AAP) was the first-line strategy. The combination of AD and AAP was recommended as the first-line for the MDE with psychotic features as well. When treatment response to initial AD monotherapy was insufficient, a combination of AAP or another AD was recommended. In the case of unsatisfactory response to initial treatment with an AD and AAP combination, switching to another AAP or adding another AD was recommended.
Conclusion
Generally, there were no significant changes in the recommendations for MDE management in the KMAP-DD 2021 compared to previous versions. However, it was notable that the preference for the use of AAP and AD with the novel mechanism of action including vortioxetine and agomelatine increased.
7.Korean Medication Algorithm Project for Depressive Disorder 2021 (III): Child and Adolescent
Chan-Mo YANG ; Se-Hoon SHIM ; Won-Myong BAHK ; Young Sup WOO ; Jong-Hyun JEONG ; Sheng-Min WANG ; Won KIM ; Jeong Seok SEO ; Jung Goo LEE ; Young-Min PARK ; Seung-Ho JANG ; Myung Hun JUNG ; Hyung Mo SUNG ; IL Han CHOO ; Bo-Hyun YOON ; Sang-Yeol LEE ; Duk-In JON ; Kyung Joon MIN
Journal of Korean Neuropsychiatric Association 2021;60(3):193-203
Objectives:
The Korean Medication Algorithm Project for Depressive Disorder 2021 (KMAP-DD 2021) was a revision of previous works. The main purpose of the current study was to amend guidelines for the treatment of a major depressive disorder (MDD) for children and adolescents.
Methods:
The survey consisted of 21 questionnaires for children and adolescents. A total of 33 of the 46 experts in child and adolescent psychiatry answered the survey.
Results:
Antidepressant (AD) monotherapy was selected as the 1st line option for MDD with mild to moderate severity. As the 1st line of treatment for MDD severe without psychotic features in children and adolescents, AD monotherapy and AD augmented with atypical antipsychotics (AAP) were recommended. For MDD with psychotic features, AD augmented with AAP was preferred as the 1st line of treatment.
Conclusion
We developed an algorithm for child and adolescent populations with depressive disorders, more specifically than the KMAP-DD 2017. We expect this algorithm will provide clinicians useful information and help in the treatment of children and adolescents with depressive disorders.
8.Korean Medication Algorithm Project for Depressive Disorder 2021 (II): The Subtypes of Depression
Young-Min PARK ; Jeong Seok SEO ; Young Sup WOO ; Won-Myong BAHK ; Won KIM ; Jong-Hyun JEONG ; Se-Hoon SHIM ; Jung Goo LEE ; Seung-Ho JANG ; Sheng-Min WANG ; Myung Hun JUNG ; Hyung Mo SUNG ; L Han CHOO ; Bo-Hyun YOON ; Sang-Yeol LEE ; Duk-In JON ; Kyung Joon MIN
Journal of Korean Neuropsychiatric Association 2021;60(3):186-192
Objectives:
The Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) was developed in 2002 and revised in 2006, 2012, 2017. In 2021, the fifth edition was published.This edition reflected new findings and the latest trends in the areas of pharmacological treatment. The aim of this study is to present strategies and treatment options according to the subtype of depression using data from the KMAP-DD-2021.
Methods:
Ninety-seven psychiatrists with clinical experience in depressive disorder were selected. The questionnaires for KMAP-DD 2021 were sent to participants via mail. KMAP-DD 2021 consists of overall treatment strategies and treatment options under specific circumstances.Each treatment strategy or treatment option was evaluated with an overall score of nine and was divided into the three phases of recommendation that include primary, secondary, and tertiary.
Results:
For persisting depressive disorder, antidepressant monotherapy including selective serotonin reuptake inhibitor (SSRI) (escitalopram, fluoxetine, sertraline, paroxetine), serotoninnorepinephrine reuptake inhibitor (SNRI) (desvenlafaxine, venlafaxine, duloxetine, milnacipran), vortioxetine, and mirtazapine, was recommended as first-line medications. For melancholia of major depressive disorder, SSRI, SNRI, vortioxetine, and mirtazapine also were recommended as first-line medications. For mixed features, SSRI, bupropion, mirtazapine, SNRI, except for duloxetine, and milnacipran were recommended as first-line medications. For anxious distress, SSRI, mirtazapine, and SNRI, except milnacipran, were recommended as first-line medications.
Conclusion
The preferences of antidepressants by experts differed according to the subtype of depression. These findings suggest that experts treat patients with a major depressive disorder after considering the subtype of depression involved.
9.Korean Medication Algorithm Project for Depressive Disorder 2021 (I): Treatment Strategies for Major Depressive Episode
Young Sup WOO ; Won-Myong BAHK ; Jeong Seok SEO ; Young-Min PARK ; Won KIM ; Jong-Hyun JEONG ; Se-Hoon SHIM ; Jung Goo LEE ; Seung-Ho JANG ; Sheng-Min WANG ; Myung Hun JUNG ; Hyung Mo SUNG ; IL Han CHOO ; Bo-Hyun YOON ; Sang-Yeol LEE ; Duk-In JON ; Kyung Joon MIN
Journal of Korean Neuropsychiatric Association 2021;60(3):174-185
Objectives:
The Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) is a consensus-based medication guideline. To reflect advances in pharmacotherapy for depressive disorders, we have undertaken a fourth revision of the KMAP-DD.
Methods:
The review committee for the new version of the KMAP-DD (KMAP-DD 2021) included 143 Korean psychiatrists with clinical experience in the field of depressive disorders. Each treatment strategy or treatment option was evaluated with an overall score of nine, and the treatment option was categorized into the three levels of recommendation of primary, secondary, and tertiary.
Results:
The first-line pharmacotherapeutic strategy for mild to moderate major depressive episodes (MDE) was antidepressant (AD) monotherapy. For severe MDE without psychotic features, AD monotherapy or the combination of AD and atypical antipsychotics (AAP) was the first-line strategy. The combination of AD and AAP was recommended as the first-line for the MDE with psychotic features as well. When treatment response to initial AD monotherapy was insufficient, a combination of AAP or another AD was recommended. In the case of unsatisfactory response to initial treatment with an AD and AAP combination, switching to another AAP or adding another AD was recommended.
Conclusion
Generally, there were no significant changes in the recommendations for MDE management in the KMAP-DD 2021 compared to previous versions. However, it was notable that the preference for the use of AAP and AD with the novel mechanism of action including vortioxetine and agomelatine increased.
10.Korean Medication Algorithm for Depressive Disorder 2021, Fourth Revision: An Executive Summary
Jeong Seok SEO ; Won-Myong BAHK ; Young Sup WOO ; Young-Min PARK ; Won KIM ; Jong-Hyun JEONG ; Se-Hoon SHIM ; Jung Goo LEE ; Seung-Ho JANG ; Chan-Mo YANG ; Sheng-Min WANG ; Myung Hun JUNG ; Hyung Mo SUNG ; IL Han CHOO ; Bo-Hyun YOON ; Sang-Yeol LEE ; Duk-In JON ; Kyung Joon MIN
Clinical Psychopharmacology and Neuroscience 2021;19(4):751-772
Objective:
In the 19 years since the Korean College of Neuropsychopharmacology and the Korean Society for Affective Disorders developed the Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) in 2002, four revisions have been conducted.
Methods:
To increase survey efficiency in this revision, to cover the general clinical practice, and to compare the results with previous KMAP-DD series, the overall structure of the questionnaire was maintained. The six sections of the questionnaire were as follows: 1) pharmacological treatment strategies for major depressive disorder (MDD) with/without psychotic features; 2) pharmacological treatment strategies for persistent depressive disorder and other depressive disorder subtypes; 3) consensus for treatment-resistant depression; 4) the choice of an antidepressant in the context of safety, adverse effects, and comorbid physical illnesses; 5) treatment strategies for special populations (children/adolescents, elderly, and women); and 6) non-pharmacological biological therapies. Recommended first-, second-, and third-line strategies were derived statistically.
Results:
There has been little change in the four years since KMAP-DD 2017 due to the lack of newly introduced drug or treatment strategies. However, shortened waiting time between the initial and subsequent treatments, increased preference for atypical antipsychotics (AAPs), especially aripiprazole, and combination strategies with AAPs yield an active and somewhat aggressive treatment trend in Korea.
Conclusion
We expect KMAP-DD to provide clinicians with useful information about the specific strategies and medications appropriate for treating patients with MDD by bridging the gap between clinical real practice and the evidence-based world.