1.Staging problems of lung cancer.
Tuberculosis and Respiratory Diseases 2000;49(4):391-411
No abstract available.
Lung Neoplasms*
;
Lung*
2.The Dosimetry of Radiosurgery using of Rando Phantom.
Sung Kyu KIM ; Sei One SHIN ; Myung Se KIM
Yeungnam University Journal of Medicine 1990;7(1):113-119
The stereotactic radiosurgery using ionizing radiation of high energy is a technique for exadicating intracranial small tumors, which are inaccessible or unsuitable for open surgical technique. For such a small field radiosurgery, TLD or film dosimetry is essential. The three dimensional dose planning of radiosurgery was performed with dose planning computer system (Therac 2300). The target dose distribution and its error according to patient position were discussed. And were measured of circular cone which specially designed in our Hospital. The position error of Rando Phantom compared with CT were 0.4 mm in the AP-LAT section and in the AP-VERT section, 1.0 mm in the AP-VERT 45°section. The ratio of accuracy of the gantry and couch rotation were 1.5 mm diameter for central axis of 18MeV linear accelerator. Our study suggested that radiosurgery of small field in out department will be appropriate for clinical application.
Computer Systems
;
Film Dosimetry
;
Humans
;
Particle Accelerators
;
Radiation, Ionizing
;
Radiosurgery*
3.Pallative effect of radiation therapy in management of symptomatic osseous metastases.
Sei One SHIN ; Sung Kyu KIM ; Myung Se KIM
Yeungnam University Journal of Medicine 1992;9(1):102-109
Bone metastases represent an important and frequent clinical problem in patients with advanced cancers. Especially, painful bone metastases are common features in these patients. Radiotherapy is an effective tool for palliative aim of painful metastatic osseous lesions. Various treatment results have been previously reported. The present retrospective study was aimed to evaluate the efficacy of palliative irradiation on pain relief, with the goal of selecting appropriate irradiation dose schedule. Radiotherapy consisted of 5 times a week with a various fractional dose between 180 and 400cGy. The response of pain relief and the survival time after completion of radiotherapy are related to total dose and most of the patients have shown a similar response by the end of radiotherapy. The higher dose and the more aggressive multimodality treatment, the better pain control and the longer survival time.
Appointments and Schedules
;
Humans
;
Neoplasm Metastasis*
;
Radiotherapy
;
Retrospective Studies
4.A Study on the dosimetry in boundary of shielding block in high energy irradiation.
Myung Se KIM ; Sung Kyu KIM ; Sei One SHIN
Yeungnam University Journal of Medicine 1990;7(2):115-120
Scatter-air ratios are used for the purpose of calculating scattered dose in the medium. The computation of the primary and the scattered dose separately is particularly useful in the dosimetry of irregular fields with shielding block in radiation field, dose distribution of scattered radiation using 18MeV Linear accelerator and Co-60 teletherapy measured. The effect of scattered radiation dose by protecting block was been ignored in radiation therapy, 2-3% of scattered radiation may be 90-200cGy which could be influence vital complication such as cataract, oligospermia or sterility. So that exact calculate scattered radiation by protecting block exactly for irregular field c small protection of vital organ is very important. The purpose of this article is to calculate scattered radiation by protecting block exactly for irregular field c Linac or Co-60 irradiation and to applicate these data in clinical radiation field. Authors could obtain following results. 1. The lesser angle between shielding block showed more scattered radiation. 2. With decreasing distance between shielding blocks, the dependent of scattered radiation were increased. 3. Output of 18 MeV Linear accelerator and Co-60 was related linear proportion on field size, but independent according to the size of shielding block in 18 MeV Linear accelerator.
Cataract
;
Infertility
;
Male
;
Oligospermia
;
Particle Accelerators
5.Radiation Therapy of Head and Neck Cancer with CO-6O HDR Transcatheteric Irradiation.
Sei One SHIN ; Sung Kyu KIM ; Myung Se KIM
Yeungnam University Journal of Medicine 1990;7(2):109-114
The basic strategy of irradiation is to deliver a dose to the cancer that is high enough to make cancer cells incapable of reproduction, while keeping the doses to the various healthy tissues below tolerable levels. In order to improve local control and survival, as a boost therapy after external radiotherapy, high dose rate transcatheteric irradiation using remote control after loading system (RALSTRON-20B) was used for twelve patients with head and neck cancers. Present results showed complete remission of cancer in 9 out of 112 patients without treatment related complications. Although this procedure is easy to operate, well trained skillful hand in essential for good results. Furthermore out experience suggested that meticulous treatment planning should be developed for better results.
Hand
;
Head and Neck Neoplasms*
;
Head*
;
Humans
;
Neck
;
Radiotherapy
;
Reproduction
6.Radition effect on colony formation of hela.S3(SC) cell line.
Sei One SHIN ; Sung Kyu KIM ; Myung Se KIM
Yeungnam University Journal of Medicine 1993;10(1):212-217
Since discovery of X-rays, radiotherapy has evolved into one of the most scientific branches of medicine and has established its role as the primary line or the secondary line of attack, after surgery,. in the treatment of malignant cancers. Nowadays its importance is illustrated by the fact that as many as 70 per cent of all pastients with cancer will receive radiation therapy at sometime during their disease process. Biologic effects-of X-rays began to be apparant soon after the discovery by Roentgen in 1895. In clinical radiotherapy, the biologic endpoint of most importance is loss of cellular reproductive ability or clonogenicity. One of the commonest ;nays to assess cell survival is to use an in vitro plating assay. We analyzed radiation effect on colony formation of HaLa. S3(SC) cell line and obtained results are as follows The plating efficiency is 0.464. The shape of cell survival curve is similar to multi-target plus single hit component model. Estimated values of Do, Dq, and extrapolation number are 150 cGy, 80 cGy and 1.7 respectively. We reported these experimental data with review of literature.
Cell Line*
;
Cell Survival
;
Radiation Effects
;
Radiotherapy
7.Therapeutic Results of Radiotherapy in Nonsmall Cell Lung Cancers.
Sei One SHIN ; Sung Kyu KIM ; Myung Se KIM
Yeungnam University Journal of Medicine 1994;11(1):72-81
Total 55 patients with nonsmall cell lung cancer treated with radiation therapy at Department of Therapeutic Radiology, Yeungnam University Hospital, between May-1 1986 and April-30 1993 were retrospectively analyzed by clinical characteristics, failure patterns follow up duration and survival ratio according to prognostic factors. Obtained results were as follows : 1. Male to female ratio was 17.3 2. Sixth and seventh decades were predominant age group. 3. The patients were 8 in stage I-II, 34 in stage IIIA, 13 in stage IIIb, respectively. 4. Forty five patients out of 55 were squamous cell carcinoma. 5. Primary tumor were originated from upper lobe bronchi predominantly. 6. The size of the primary tumor, lymph node involvement and the degree of differentiation were important in evaluation of prognosis. 7. In conclusion, for patients with poor prognostic factors systemic chemotherapy and multidisciplinary approach were recommended for better treatment outcome and improvement of survival.
Bronchi
;
Carcinoma, Non-Small-Cell Lung
;
Carcinoma, Squamous Cell
;
Drug Therapy
;
Female
;
Follow-Up Studies
;
Humans
;
Lung Neoplasms*
;
Lung*
;
Lymph Nodes
;
Male
;
Prognosis
;
Radiation Oncology
;
Radiotherapy*
;
Retrospective Studies
;
Treatment Outcome
8.A Study on ARC Therapy of 18MeV Linear Accelerator.
Seong Kyu KIM ; Sei One SHIN ; Myung Se KIM
Yeungnam University Journal of Medicine 1988;5(2):31-36
In recent years there has been a growing interest in all forms of rotational therapy, and many different types of therapy machines designed for this kind of treatment have become available. To the medical radiation physicist, the dosimetry of rotation therapy has presented a number of interesting problems, and much useful work has been published on the basic date of dose distribution and dosage calculation. The setting dose for ARC therapy were obtained by computer calculation and measurement with cylindrical phantom. Authors compared computer calculation with measured value. And in ARC therapy, the region of maximum dose in shifted from the tumor center. The extent of shift was analyzed by isodose distribution for ARC therapy techniques.
Particle Accelerators*
9.A study on dose distribution of small irradiation field in the electron therapy.
Sung Kyu KIM ; Sei One SHIN ; Myung Se KIM
Yeungnam University Journal of Medicine 1991;8(2):114-120
In electron therapy, low melting point alloy is used for shaping of the field. Electron field shaping material affect the output factor as well as the collimator system. The output factors of electron beams for shaped fields from NELAC-1018 were measured using ionization chamber of Farmer type in water phantom. The output factors of electron beams depend on the incident energy, inherent collimator system and the size of shaped field. Obtained results were followings. 1. In the smaller applicator, output varied extremely according to extent of collimator opening. 2. The higher energy, the output is less varied according to treatment field at small field.
Alloys
;
Farmers
;
Freezing
;
Water
10.A study of dose distribution in postoperative radiotherapy in uterine cervical cancer.
Sei One SHIN ; Sung Kyu KIM ; Myung Se KIM
Yeungnam University Journal of Medicine 1991;8(1):166-177
Uterine cervical cancer is the most common malignancy in Korean women. In spite of recent development of early diagnostic and therapeutic modalities, about 40% of treated patient will develop relapse. So more aggressive local treatment such as more extensive surgery and higher radiation dose and administration of systemic chemotherapy will promote the curability but treatment related complications cannot be avoidable. We used 22 cases of early cervical cancer, treated with surgery and post-operative radiotherapy, clinical data of these patients were analyzed to determine relationship between clinical parameters and final outcome. Three out of 22 cases revealed relapse and one patient showed rectovaginal fistula and another patient showed small bowel obstruction and the other patient showed rectal obstruction. Two out of three recurrence were stage IIa and the other one case was stage Ib adenocarcinoma with lymphovascular involvement. Nineteen out of 22 cases were followed without remarkable side effect or treatment related complication or sequelae. We concluded that out treatment policy was safe and effective to eradicate high risk postoperative cervical cancer with acceptable side effects or complication.
Adenocarcinoma
;
Drug Therapy
;
Female
;
Humans
;
Radiotherapy*
;
Rectovaginal Fistula
;
Recurrence
;
Uterine Cervical Neoplasms*