The object of this study was to determine the radiation effect on the urinary bladder and to establish the basic date for optimal fraction schedule on the whole abdominal irradiation of the mice. Although radiation damage of the urinary bladder is one of the dose-limiting factor for treatment of lower abdominal cancer, such as uterine cervical or rectal cancer, systematic histopathological study of total dose and recovery duration is very rare, especially in conventional fractionation regimen of clinical use. Authors used 198 mice and analyzed histopathological findings according to total dose (40&50 GY) and recovery duration (1-15 weeks after completion of irradiation) The results were summarized as follows: 1. No definite difference of radiosensitivity was noted between male and female group. 2. Most of mucosal injuries were recovered within 14 weeks in 40 GY irradiated group. 3. Vascular injury and change of connective tissue were prominent and persisted even mild degree until 15 weeks after completion of irradiation in 50 GY irradiated group. 4. Although follow up duration of this study (105 days) was not enough to compare life span of mice, this study emphasized that precious schedule for treatment planning was necessary for preventing or reducing of late complication.
Animals ; Appointments and Schedules ; Connective Tissue ; Female ; Follow-Up Studies ; Humans ; Male ; Mice* ; Radiation Effects ; Radiation Tolerance ; Rectal Neoplasms ; Urinary Bladder* ; Vascular System Injuries

Giardiasis is one of the most common causes of infectious diarrhea and it has a worldwide distribution. Although it is a relatively common disorder, histologically confirmed Giardiasis is a rare occurrence and there have been no previous reports in Korea. A 34-year-old man presented with a 2-year history of epigastric discomfort and left flank pain. On stool examination, many cystic forms of Giardia lamblia were noted. In biopsy specimens of the small intestine, there was moderate chronic inflammatory cell infiltration and several trophozoites of Giardia were observed in the intervillous space and luminal surface. The trophozoites were pear shaped symmetrical organisms with two nuclei, and measured 9~10 micrometer in length.
Male ; Humans ; Biopsy

No abstract available.
Carcinoma, Renal Cell* ; Colon* ; Colonic Neoplasms*

Sodium hypochlorite alkaline was tested against Pseudomonas tolaasii causing bacterial blotch on cultivated oyster mushroom (Pleurotus ostreatus). The minimum inhibitory concentration of sodium hypochlorite against P. tolaasii contained active chlorine (AC) at 1.4 mg/l on plate assay. The highest cultivation yield was obtained from the treatment of AC 5.7 mg/l. Treatment of sodium hypochlorite at the rate of higher than AC 11.4 mg/l resulted in reduced yields at the harvest. However, the population of total bacteria on the bed surface treated with AC 5.7 mg/l of sodium hypochlorite was maintained to some extent. Inhibitory concentration against total bacteria on the bed surface was over AC 22.8 mg/l. Mushroom mycelium was damaged and its growth strongly inhibited at the concentration of AC 200 mg/l. Mushroom caps showed yellowish symptom by chemical injury by treatments of AC 74.1 mg/l or higher. Sporocarps infected by P. tolaasii were irrevocable at any concentration of sodium hypochlorite. Routine watering with AC 5.7 mg/l from mushroom initiation to the end of picking resulted in reduced bacterial blotch incidence of 40% and 86% at two mushroom farms. The treatment resulted in higher quality mushroom production compared to that conventionally watered with tap water alone.
Agaricales ; Bacteria ; Chlorine ; Incidence ; Microbial Sensitivity Tests ; Mycelium ; Pleurotus* ; Pseudomonas ; Sodium Hypochlorite* ; Sodium* ; Water

The clinicopathologic features and the comparative analysis of diagnostic methods in 42 patients having intestinal tuberculosis were studied. In all the cases, clinical and colonoscopic diagnosis was confirmed by histological examination. Abdominal pain was the most common symptom (54%). Twenty nine patients had active pulmonary tuberculosis which was confirmed by a chest X-ray, or an AFB smear and a culture of sputum. A transverse ulcer with surrounding hypertrophic mucosa and multiple erosion was the usual colonoscopic findings. The granulomas were usually located in the just upper and lower portion of muscularis mucosa. The direct smear and culture of the fresh biopsy material showed AFB in 11 (32.4%) and 12 cases (36.4%) respectively. Ziehl-Neelsen staining in serially sectioned slides from formalin-fixed, paraffin- embedded tissue revealed AFB in 15 cases (35.7%). An immunohistochemical stain for Mycobacterium bovis was done in all cases and 13 cases were positive (31%). A polymerase chain reaction (PCR) was done and showed positivity in 4 out of 20 cases of fresh biospy material and 12 out of 40 cases in paraffin embedded tissue. For the conclusive diagnosis of intestinal tuberculosis, a Ziehl-Neelsen stain is the most sensitive, fast, and cost-effective method. The diagnostic accuracy will be increased when other diagnostic methods such as tissue culture and PCR are coupled with this simple staining method.
Abdominal Pain ; Biopsy ; Diagnosis* ; Granuloma ; Humans ; Intestines ; Mucous Membrane ; Mycobacterium bovis ; Paraffin ; Polymerase Chain Reaction ; Sputum ; Thorax ; Tuberculosis* ; Tuberculosis, Pulmonary ; Ulcer

Application of electric current in peritoneal dialysis was performed to observe the change of small intestine movement through an abdominal window, and to acceleration migration of certain ions. Prominent elevation of potassium in the dialysate was seen after applying a negative charge in the peritoneal cavity. N.P.H. was not much effected by introduction of the electric current. Acceleration of small intestinal movement was also observed after the application of electric current in peritoneal dialysis. Sow intestinal movement, when large amounts of lavage fluid are present in the peritoneal cavity, will be moderatelyaccelerated as a result of the application of electric current. Electric current can be applied both to prevent distension of the abdomen and adynamic ileus in peritoneal dialysis, and to accelerate too migration of the potassium ion and certain other ions.
Abdomen ; Acceleration ; Ileus ; Intestine, Small ; Ions ; Peritoneal Cavity ; Peritoneal Dialysis* ; Potassium ; Therapeutic Irrigation

Observation of intestinal movement in rabbits were performed through use of an abdominal window in peritoneal dialysis. The causes of an adequate drainage were also observed, through the abdominal window, and better drainage was obtained as a result of clear vision and catheter adjustment. Generally it was observed that the amount of small intestinal movement diminishes after dialysis solution was introduced into the peritoneal cavity, and the larger the amount of solution, the slower the small intestinal movement. The smaller dosage is better for effecting a diminished intestinal movement; however, the effect of the dialysis is not so great, because all the surface of the peritoneum can not be used. On the other hand, the larger dosage brings on a slowing down of the intestinal movement; yet its effect on the peritoneal dialysis is greater. Our observation lead us to conclude that 200cc of solution is more popular for rabbit experiment and that dosage above this should be avoided. Less influence to the small intestinal movement was noticed when the temperature of the solution remained a little higher than body temperature. The nephrectomized rabbits and the anuric rabbits show less intestinal movement than the normal rabbits. The possible causes of ilus and abdominal distension in peritoneal dialysis were noted and discussed. After giving prostigmin in dialysate the frequency of intestinal movement increased almost to normal. Judging from the result of this experiment, it is advisable to use small doses of prostigmin in dialysate routinely in peritoneal dialysis.
Body Temperature ; Catheters ; Dialysis ; Drainage ; Hand ; Neostigmine ; Peritoneal Cavity ; Peritoneal Dialysis* ; Peritoneum ; Rabbits

No abstract available.
Antibody Formation* ; Immunoglobulin A* ; T-Lymphocytes*

No abstract available.
Perfusion*

PURPOSE: The aim of this study was to investigate and identify work environment, job embeddedness, and burnout among general hospital nurses in Korea. METHODS: The participants were 563 clinical nurses working in 13 general hospitals across the country. Data were analyzed using SPSS and Microsoft Excel programs. RESULTS: Mean scores were 2.62 for nurses' work environment, 2.97 for job embeddedness, and 3.61 for burnout. Nurses' work environment showed a positive correlation with job embeddedness (r=.70, p<.001), but a negative correlation with burnout (r=-.49, p<.001). Subcategories of nurses' work environment that predicted job embeddedness included satisfaction and happiness, hospital support for the work environment, patient care environment, satisfaction with work schedule, manager leadership, supportive environment for nurses' work, and computer problems. Subcategories of nurses' work environment that predicted burnout included satisfaction and happiness, violence within ward, hospital support for work environment, and patient care environment. CONCLUSION: Findings from this study indicate the need to evaluate and improve the work environment for nurses to increase job embeddedness and control burnout. Future studies should explore ways in which turnover intention can be decreased by changing nurses' work environment.
Appointments and Schedules ; Happiness ; Hospitals, General* ; Intention ; Korea ; Leadership ; Patient Care ; Violence