No abstract available.
Animals ; Dogs* ; Lactic Acid*

No abstract available.
Catheterization* ; Catheters* ; Hemothorax* ; Subclavian Vein*

It is rare to meet an uncontrolled hyperthyroid patient in elective surgery. But, in emergency surgery, recognition of hyperthyroidism may be difficult, as trauma or pain may mask hyperthyroidism. The patient may be unaware of its existence or incapable of transmitting the information. During or after surgery, untreated hyperthyroidism can cause thyrotoxic crisis (thyroid storm), which may be a highly fatal complication. Thyrotoxic crisis is an extreme accentuation of signs and symptoms of throtoxicosis. Clinical manifestations are sinus tachycardia or atrial fibrillation, marked increase in systolic pressure and pulse pressure, high temperature, profuse sweating, tremor, dehydration, tachypnea, extreme restlessness and agitation, delirium, and frank psychosis. In this case, atrial fibrillation and hypertension developed after induction, and severe thyrotoxic symptoms appeared after emergence, which were caused by undetected hyperthyroidism.
Anesthesia* ; Atrial Fibrillation ; Blood Pressure ; Dehydration ; Delirium ; Dihydroergotamine ; Emergencies ; Humans ; Hypertension ; Hyperthyroidism ; Masks ; Psychomotor Agitation ; Psychotic Disorders ; Sweat ; Sweating ; Tachycardia, Sinus ; Tachypnea ; Thyroid Crisis ; Tremor

Experiences with propofol in pediatric anesthesia are limited. We undertook a study to evaluate the quantity of induction and recovery from anesthesia with propofol compared to thiopental/halothane. Fifty children received 2mg/kg of propofol as a loading dose followed by a maintenance dose of 9mg/kg/hr for first 30minutes and followed by 6mg/kg/hr there- after. Fifty children received 5mg/kg of thiopental, and maintensnce was provided with halothane (0.5%-1.5%). The interval between the end of the administration of propofol or thiopental/halothane and extubation, as well as discharge to the ward,was significantly shorter with propofol (5.43 versua 10.72 min and 10.30 versus 18.20 min, respectively). Pain on injection site were seen more frequently with propofol, whereas nausea and hiccup were only observed with thiopental. During the first 6 hour after the surgical procedure, an- algesics were needed significantly more often in the thiopental group. In conclusion, propofol used as a single anesthetic for total intravenous anesthesia is a satisfactory agent for oph- thalmic surgery of short duration in children.
Anesthesia ; Anesthesia, Intravenous ; Child* ; Halothane* ; Hiccup ; Humans ; Nausea ; Propofol* ; Thiopental*

This study was carried out to manifest risk factors related grain dust induced asthma, especially allergic and immunologic factors. Six grain workers first diagnosed as grain dust induced asthma by specific antigen bronchial asthma challenge test (cases) and 37 grain workers showed negative finding (controls) in the same firm were selected. Questionnaire survey for respiratory symptoms, interview, physical examination, PFT, methacholine bronchial hyperresponsiveness, specific challenge tests and skin prick test for four grains (grain, corn, rye and seed dust) were conducted. To evaluate the role of specific antibodies to grain dust, we detected serum specific IgE and IgG antibodies by ELISA in 43 employees. The results were summarized as follows : 1. Compared with the group having no respiratory symptoms, odds ratio of grain dust induced asthma with respiratory symptoms was 3.04 (95% CI 0.32-28.80). 2. Compared with the group having no ventilatory impairment, odds ratio of grain dust induced asthma with ventilatory impairment was 0.54 (95% CI 0.06-5.21). 3. Compared with the group showed negative skin test for general respirable antigen, odds ratio of grain dust induced asthma with atopy was 8.02 (95% CI 0.42-153.25). 4. Compared with the group showed negative finding on specific allergic skin test, odds ratio of grain dust induced asthma with positive finding was 5.88 (95% CI 0.63-55.38). 5. In immunologic test, compared with the group not increased total IgE(<160 IU/ml), odds ratio of grain dust induced asthma with increased group (> or = 160 IU/ml) was 4.78 (95% CI 0.50-44.57). 6. Compared with the group showed negative finding on specific IgE antibody, odds ratio of grain dust induced asthma with positive finding was 2.63 (95% CI 0.43-16.16). 7. Compared with the group showed normal finding on nonspecific (methacholine) bronchial hyperresponsiveness, odds ratio of grain dust induced asthma with positive finding was 76.82(95% CI 3.37 - 1566.34). Statistically significant odds ratio were fecund for specific skin test with grain, total IgE and nonspecific (methacholine) bronchial hyperreponsiveness.
Antibodies ; Asthma ; Asthma, Occupational* ; Cereals* ; Dust ; Enzyme-Linked Immunosorbent Assay ; Immunoglobulin E ; Immunoglobulin G ; Immunologic Factors ; Immunologic Tests ; Methacholine Chloride ; Odds Ratio ; Physical Examination ; Questionnaires ; Risk Factors* ; Secale cereale ; Skin ; Skin Tests ; Zea mays

This study was carried out to manifest risk factors related grain dust induced asthma, especially allergic and immunologic factors. Six grain workers first diagnosed as grain dust induced asthma by specific antigen bronchial asthma challenge test (cases) and 37 grain workers showed negative finding (controls) in the same firm were selected. Questionnaire survey for respiratory symptoms, interview, physical examination, PFT, methacholine bronchial hyperresponsiveness, specific challenge tests and skin prick test for four grains (grain, corn, rye and seed dust) were conducted. To evaluate the role of specific antibodies to grain dust, we detected serum specific IgE and IgG antibodies by ELISA in 43 employees. The results were summarized as follows : 1. Compared with the group having no respiratory symptoms, odds ratio of grain dust induced asthma with respiratory symptoms was 3.04 (95% CI 0.32-28.80). 2. Compared with the group having no ventilatory impairment, odds ratio of grain dust induced asthma with ventilatory impairment was 0.54 (95% CI 0.06-5.21). 3. Compared with the group showed negative skin test for general respirable antigen, odds ratio of grain dust induced asthma with atopy was 8.02 (95% CI 0.42-153.25). 4. Compared with the group showed negative finding on specific allergic skin test, odds ratio of grain dust induced asthma with positive finding was 5.88 (95% CI 0.63-55.38). 5. In immunologic test, compared with the group not increased total IgE(<160 IU/ml), odds ratio of grain dust induced asthma with increased group (> or = 160 IU/ml) was 4.78 (95% CI 0.50-44.57). 6. Compared with the group showed negative finding on specific IgE antibody, odds ratio of grain dust induced asthma with positive finding was 2.63 (95% CI 0.43-16.16). 7. Compared with the group showed normal finding on nonspecific (methacholine) bronchial hyperresponsiveness, odds ratio of grain dust induced asthma with positive finding was 76.82(95% CI 3.37 - 1566.34). Statistically significant odds ratio were fecund for specific skin test with grain, total IgE and nonspecific (methacholine) bronchial hyperreponsiveness.
Antibodies ; Asthma ; Asthma, Occupational* ; Cereals* ; Dust ; Enzyme-Linked Immunosorbent Assay ; Immunoglobulin E ; Immunoglobulin G ; Immunologic Factors ; Immunologic Tests ; Methacholine Chloride ; Odds Ratio ; Physical Examination ; Questionnaires ; Risk Factors* ; Secale cereale ; Skin ; Skin Tests ; Zea mays

Intrathecal injection of morphine is widely used for relief of postoperative pain and the method is generally considered to provide excellent analgesia. Howerver adverse side effects such as respiratory depression, pruritus, vomiting and urinary retention occur following intrathecal injection of morphine. Among the side effects, urinary retention is destressing and troublesome. We have studied the effects of naloxone and neostigmine on urinary retention following intrathecal injection of morphine for the management of postoperative pain in 60 cases. The results were as follows. 1) Mean duration of urinary retention following intrathecal injection of morphine was 24.1+/-7.4 hours. 2) There was no statistical effect of neostigmine 1.0 mg i.m. in treating urinary retention due to intrathecal injection of morphine. 3) Single or repeated intravenous injections of naloxone were successful in treating urinary retention following intrathecal injection of mrphine. To treat urinary retention, a single dose of 0.8mg naloxone was more effective than a single dose of 0.4mg naloxone.
Analgesia ; Injections, Intravenous ; Injections, Spinal* ; Morphine* ; Naloxone ; Neostigmine ; Pain, Postoperative ; Pruritus ; Respiratory Insufficiency ; Urinary Retention ; Vomiting

This study examined the protective effect of dexamethansone following bilateral forebrain ischemia in a rat model of two-vessel occlusion. Twenty rats were subjected to dexamethasone (1 mg/kg intravenously) before bilateral common carotid artery occlusion for 10 minutes. Carotid artery blood flow was restored and the rats were terminated by a perfusion-fixation method after 7 days. Ten minutes of two-vessel occlusion produced cellular ischemic change in the cerebral hemispheres of most rats. This region was studied mainly with light microscope, and it was noticed that the CA 1 neuron in the hippocampus is the most vulnerable to ischemia. Ischemic neuronal damage was graded in accordance with conventional neuropathological criteria. The grade had no statistical significance.
Animals ; Carotid Arteries ; Carotid Artery, Common ; Cerebrum ; Dexamethasone* ; Hippocampus ; Ischemia ; Models, Animal ; Neurons ; Prosencephalon* ; Rats

No abstract available.
Animals ; Brain* ; Ischemia* ; Prosencephalon* ; Rats*

We studied the association of nonspecific bronchial hyperresponsiveness with general characteristics, exposure concentration, respiratory symptoms, chest x-ray findings, past histories and pulmonary function. We determined bronchial hyperresponsiveness by methacholine challenge test. And we conducted a respiratory symptom questionnaire and performed spirometry on 111 workers occupationally exposed to isocyanates in various industries. About 21.6% of subjects had bronchial hyperresponsiveness. No significant differences were observed between the hyperresponsive and non-responsive group with respect to age, sex, employment period, height, and smoking histories cough and breathlessness were significantly associated with the bronchial hyperresponsiveness. The hyperresponsive group had more experience of bronchitis and asthma in the past than the non-responsive group. The lower FEV1 and FEV1 % were closely related with bronchial hyperresponsiveness. Bronchial hyperrespoosiveness seems to be associated with some of respiratory symptoms, past histories and pulmonary function parameters in workers exposed to isocyanates.
Asthma ; Bronchitis ; Cough ; Employment ; Isocyanates* ; Methacholine Chloride ; Occupations ; Surveys and Questionnaires ; Smoke ; Smoking ; Spirometry ; Thorax