OBJECTIVES: Aim of this study was to compare quality of life (QOL) in obsessive compulsive disorder (OCD), panic disorder (PD) and healthy controls. Additionally, relationship between clinical factors in patients and their QOL were explored. METHODS: 49 patients with OCD, 109 patients with PD and 54 healthy controls were recruited. Total scores and scores of each domain of WHO Quality of Life scale (WHOQOL) were compared in the three groups. Correlation analysis and regression analysis were performed to examine the relationship between QOL and the clinical characteristics in the patient group. RESULTS: Total scores and scores of all domains except environmental domain of WHOQOL in patient group were decreased compared to those in healthy control. Scores of social and psychological domains in the OCD group were lower than those in the PD group. The severity of agoraphobia and depression were factors affecting the QOL in the PD group. For the OCD group, comorbid depression was related to social and psychological domain of WHOQOL. CONCLUSION: QOL in patients with OCD and PD was poorer than that of healthy controls. Social relationships and psychological functioning may be poorer in patients with OCD than patients with PD. The severity of depression and agoraphobia predicted QOL in patients with PD. Comorbid depression in OCD might be a predictor of poor QOL.
Agoraphobia ; Depression ; Humans ; Obsessive-Compulsive Disorder* ; Panic Disorder* ; Panic* ; Quality of Life*

To delineate the coronary anatomy and left ventricular function during early myocardial infarction, coronary arteriography and left ventriculogrphy were performed, prospectively in 23(22%) of 105 patients who were admitted to the coronary care unit at Masan Koryo Hospital from June 1986 to June 1988 within 4 weeks after the onset of symptoms(medium:21 days, range:18 days to 25 days). 1) Among 23 patients, male is 20 patients and female is 3 patients. The ratio of male to female was 6.6:1. The mean age was 55.4+/-10.3 years(range:34-77 years). 2) Coronary artery narrowing state which related to myocardial infarction was as follows; 2 patients(7%) had normal, 1 patients(4%) had insignificant narrowing(below 50%) 5 patients(22%) had moderate narrowing(50-75%), 10 patients(43%) had severe narrowing(75-99%), 5 patients(22%) had complete occlusion(100%). 3) The range of coronary artery disease was as follows; 9 patients had one vessel disease, 10 patients had two vessel disease, 1 patients had three vessel disease, and ejection fraction had no significant difference among 3 groups but lowest in three vessel disease. Among 23 patients, 13 patients had anterior infarction, 10 patients had inferior infarction. 4) Left ventricular ejection fraction and multiple vessel disease had no significant difference between i) the young(under 45 years old) and the old(over 45 years old) age groups, ii) presence or non presence of previous angina, iii) Killip classification I, II and III, IV) anterior infarction and inferior infarction. 5) In left ventriculography, akinesis and dyskinesis were shown at similar ratio in anterior infarction and inferior infaraction. Dyskinesis was shown in 27% of patients who have 0-1 vessel disease, 50% of patients who have 2-3 vessel disease, 62% of patients who have collateral circulation, 26% of patients who dose not have collateral circulation. 6) Collateral circulation was found in 8 patients(35%). Age and left ventricular ejection fraction were high in patients without collateral circulation than with collateral circulation, but there is no significant difference and collateral circulation exists regardless of infarction site and range of coronary artery disease. 7) As for the complication of angiocardiography in this study, there was ventricular tachycardia in 3 patients(13%) without mortality. It is concluded that coronary arteriography can be safely performed in early stage after acute myocardial infarction. Also good prognosis is anticipated since three vessel disease and complete occlusion were low in acute myocardiaol infarction of Korean People. Since these are not much case performed study, however more study on this area is required.
Angiocardiography ; Angiography* ; Classification ; Collateral Circulation ; Coronary Angiography ; Coronary Artery Disease ; Coronary Care Units ; Coronary Vessels ; Female ; Humans ; Infarction ; Male ; Mortality ; Myocardial Infarction* ; Prognosis ; Prospective Studies ; Stroke Volume ; Tachycardia, Ventricular ; Ventricular Function, Left

No abstract available.
Osteochondroma*

McKusick-Kaufman syndrome (MKS) is an autosomal recessive multiple malformation syndrome characterized by hydrometrocolpos (HMC) and postaxial polydactyly (PAP). We report a case of a female child with MKS who was transferred to the neonatal intensive care unit of Seoul National University Children's Hospital on her 15th day of life for further evaluation and management of an abdominal cystic mass. She underwent abdominal sonography, magnetic resonance imaging, genitography and cystoscopy which confirmed HMC with a transverse vaginal septum. X-rays of the hand and foot showed bony fusion of the left third and fourth metacarpal bones, right fourth dysplastic metacarpal bone and phalanx, right PAP and hypoplastic left foot with left fourth and fifth dysplastic metatarsal bones. In addition, she had soft palate cleft, mild hydronephroses of both kidneys, hypoplastic right kidney with ectopic location and mild rotation, uterine didelphys with transverse vaginal septum and low-type imperforated anus. She was temporarily treated with ultrasound-guided transurethral aspiration of the HMC. Our patient with HMC and PAP was diagnosed with MKS because she has two typical abnormality of MKS and she has no definite complications of retinal disease, learning disability, obesity and renal failure that develop in Bardet-Biedl syndrome, but not in MKS until 33 months of age. Here, we describe a case of a Korean patient with MKS.
Abnormalities, Multiple ; Anal Canal ; Bardet-Biedl Syndrome ; Child ; Cystoscopy ; Female ; Foot ; Hand ; Heart Defects, Congenital ; Humans ; Hydrocolpos ; Hydronephrosis ; Infant, Newborn ; Intensive Care, Neonatal ; Kidney ; Learning Disorders ; Magnetic Resonance Imaging ; Metacarpal Bones ; Metatarsal Bones ; Obesity ; Palate, Soft ; Polydactyly ; Renal Insufficiency ; Retinal Diseases ; Uterine Diseases

OBJECTIVES: Asian migrant workers in Korea have various ethnicities. The purpose of this study was to evaluate the difference in spirometric interpretation made using the set of third National Health and Nutrition Examination Survey (NHANES III) reference equations and the relevant ethnicity-specific reference sets. METHODS: Spirometry was performed on 166 migrant and 498 Korean male workers between March and November 2012. We analyzed the spirometric data of healthy never-smokers. Spirometric patterns were evaluated using the NHANES III reference set and some relevant ethnicity-specific equations (Eom's equation for Koreans, Ip's equation for East Asians, Crapo's equation for Central Asians, Memon's equation for South Asians, and Gnanou's equation for Southeast Asian people). RESULTS: In all migrant groups except the Central Asian group, the forced expiratory volume in 1 second percentage (FEV1%) and forced vital capacity percentage (FVC%) calculated using each of the ethnicity-specific reference equations considered were significantly higher than those calculated using the NHANES III reference set. This study showed that in the evaluation of the spirometric result of subjects from Southeast Asia or South Asia, the percentage of cases with an abnormal FEV1 or FVC increased when the NHANES III set of equations was used as compared to when the ethnicity-specific equations were used. CONCLUSIONS: We found that the spirometric results of all ethnic groups were higher and the composition of the abnormal spirometric result was lower when the ethnicity-specific reference equations were used instead of the NHANES III reference set.
Asia ; Asia, Southeastern ; Asian Continental Ancestry Group* ; Ethnic Groups ; Forced Expiratory Volume ; Humans ; Korea* ; Male ; Nutrition Surveys ; Spirometry ; Transients and Migrants* ; Vital Capacity

OBJECTIVE: Small bowel series (SBS) may be a useful test in identifying the causes of feeding intolerance in preterm infants. Unfortunately, little is known about the safety and effectiveness of SBS in preterm infants. By scrutinizing our recent experiences in performing SBS in preterm infants, we aim to provide basic data concerning the use of SBS in preterm infants with feeding intolerance. METHODS: Between January 2005 and October 2008, SBS was done in 46 preterm infants with feeding intolerance, who were admitted to the neonatal intensive care unit (NICU) of Seoul national university children's hospital. We conducted a retrospective analysis of these preterm infants. RESULTS: The average gestational age and birth weight of the 46 infants were, 30(+1)+/-3(+5) weeks, 1,435+/-623 g, respectively. The mean postconceptional age when SBS was done, was 37(+2)+/-4(+2) weeks, 46.8+/-27.3days. SBS proved that 29 infants did not have mechanical obstructions and 22 of these infants had delayed bowel transit time. Eventually, 35 infants attained full feeding except those who underwent operation. SBS was done at their bedside in 15 out of 27 infants in the group less than 1.5 kg. History of NEC, meconium related ileus, and gastrointestinal operation were more frequent in the group less than 1.5 kg. The adverse effects of SBS in preterm infants included vomiting, delayed transit of the contrast media, all of which resolved in the end and there were no reports of aspiration or sepsis. CONCLUSION: Actively performing SBS test in preterm infants with feeding intolerance will promote feeding advancement by discovering the cause of feeding intolerance and subsequent management of the specific problem.
Birth Weight ; Contrast Media ; Gestational Age ; Humans ; Ileus ; Infant ; Infant, Newborn ; Infant, Premature ; Intensive Care, Neonatal ; Meconium ; Retrospective Studies ; Sepsis ; Vomiting

Complex regional pain syndrome (CRPS) is a painful and disabling disorder that can affect one or more extremities. Unfortunately, the knowledge concerning its natural history and mechanism is very limited and many current rationales in treatment of CRPS are mainly dependent on efficacy originated in other common conditions of neuropathic pain. Therefore, in this study, we present a case using a total spinal block (TSB) for the refractory pain management of a 16-year-old male CRPS patient, who suffered from constant stabbing and squeezing pain, with severe touch allodynia in the left upper extremity following an operation of chondroblastoma. After the TSB, the patient's continuous and spontaneous pain became mild and the allodynia disappeared and maintained decreased for 1 month.
Adolescent ; Chondroblastoma ; Extremities ; Humans ; Hyperalgesia ; Male ; Natural History ; Neuralgia ; Pain, Intractable ; Upper Extremity