No abstract available.
Colon* ; Rats, Sprague-Dawley* ; Rectum*

PURPOSE: Various methods of scleral fixation for the cases of posterior chamber intraocular lens (PCL) dislocation or subluxation into the vitreous cavity had been developed, and in the recent year a modification of internal scleral fixation using a hollow-bore needle has been introduced. The authors endeavored to evaluate clinical usefulness of the method. METHODS: The study was conducted for four cases of PCL dislocation or subluxation. A 10-0 polypropylene suture was threaded up the internal shaft of a 30 G straight needle and retrieved. The needle containing this suture was then inserted through the bed of the partial-thickness scleral flap 1.5 mm posterior to the limbus. The loop of suture was hooked with haphic of PCL. After the needle was retracted, the haptic was captured and the suture was tied to the sclera. The same maneuver was performed for the haptic in the opposite side. RESULTS: Except for pars plana vitrectomy, time taken for the above procedure was 10~15 minutes. Postoperatively induced astigmatism of all 4 cases were less than 3 diopters on the second postoperative day. No specific complication associated with this procedure was noted. IOL remained stable without tilting or rotation 18 months after procedure. CONCLUSIONS: This modified internal scleral fixation technique must be a convenient and effective procedure for repositioning posteriorly dislocated PCL.
Astigmatism ; Dislocations* ; Lenses, Intraocular* ; Needles* ; Polypropylenes ; Sclera ; Sutures ; Vitrectomy

The duplicated origin of vertebral artery (VA) is a very rare condition. It could be easily misdiagnosed as an arterial dissection on selective catheter angiography, especially in a patient with acute cerebellar infarction of unknown etiology. We report a patient with an acute cerebellar infarction and duplicated origin of the left VA, which was found during the selective catheter angiography.
Angiography ; Catheters ; Humans ; Infarction ; Vertebral Artery*

OBJECTIVE: Radiation therapy is an effective adjunctive therapy in the management of brain and spinal cord tumors. The damage to normal tissue, however, has been often the dose-limiting factor in radiation therapy. The purpose of this study is to see whether nimodipine, the one of calcium channel blockers, is effective for the prevention of irradiation-induced apoptosis in the rat spinal cord. METHODS: Sprague-Dawley rats were used: Control(n=12), Nimodipine-treated(0.5mg/kg, n=12). After nimodipine was administered intraperitoneally, the spinal cord of cervicothoracic junction was exposed to a single 10Gy dose of gamma rays using Ir-192. All spinal cords underwent histological examination at 4, 8, and 12 hours after irradiation, and apoptotic cells were detected by TUNEL assay and were determined by direct visual counting at magnification of x200. RESULTS: On the standard H-E stain, little evidence of histopathological change was noted within the 12 hours after irradiation. Both groups showed gradual increase of apoptotic cell counts with the lapse of time. But, in nimodipine-treated group, apoptotic cell counts were reduced significantly, compared to those of control group after irradiation, especially at 8 and 12 hours. CONCLUSION: The results suggest that nimodipine may have effects on the prevention of radiation-induced apoptosis in the spinal cord.
Animals ; Apoptosis* ; Brain ; Calcium Channel Blockers ; Cell Count ; Gamma Rays ; In Situ Nick-End Labeling ; Nimodipine* ; Rats* ; Rats, Sprague-Dawley ; Spinal Cord Neoplasms ; Spinal Cord*

No abstract available.
Lymphoma, Non-Hodgkin* ; Spinal Cord Compression* ; Spinal Cord*

SAPHO syndrome is an acronym for an increasingly recognized syndrome of synovitis, acne, pustulosis, hyperostosis, and osteitis. Most of the previously reported case are from Japan and Europe. The authors report a case of SAPHO syndrome in Korean female who presented with extrasternal neurologic symptoms. A 60-year-old female with thoracic and right chest wall pain presented with the sternocostoclavicular hyperostosis, and recurrent aseptic osteitis. Previously, she had hystrectomy and thyroidectomy due to uterine malignancy 25 years ago. Also, she started to take medications for palm and sole pustulosis 7 days prior to admission. Through evaluation of clinical, radiological, serological studies, studies was done along with bone needle biopsy for the biological reassessment. The hyperostosis was found in the pedicles of thoracic 8, 9, 10 vertebrae and sternoclavicular joint. Radio-isotope bone scan showed an accumulation of tracer in thoracic vertebra. The bone biopsy from these site showed increased osseous turnover, thickening of trabeculae accompanied by mild acculuation of granulation tissue and round cell infiltration, compatible with mild chronic inflammation with marrow fibrosis. The patient showed good response to conservative management. The authors report a case of SAPHO syndrome with thoracic radiculopathy. It is considered that SAPHO syndrome is related to spondyloarthropathy, and appears to have benign disease process with good prognosis.
Acne Vulgaris ; Acquired Hyperostosis Syndrome* ; Biopsy ; Biopsy, Needle ; Bone Marrow ; Europe ; Female ; Fibrosis ; Granulation Tissue ; Humans ; Hyperostosis ; Hyperostosis, Sternocostoclavicular ; Inflammation ; Japan ; Middle Aged ; Neurologic Manifestations ; Osteitis ; Prognosis ; Radiculopathy* ; Spine ; Spondylarthropathies ; Sternoclavicular Joint ; Synovitis ; Thoracic Wall ; Thyroidectomy

OBJECTIVE: Whereas fusion with pedicle screw fixation has shown satisfactory clinical results, solid fusion has been reported to accelerate degenerative changes in adjacent unfused levels. The purpose of this study was to evaluate the effect of bone/ligament/bone integrity after subtotal or total laminectomies on the development of adjacent segment instability (ASI). The hypothesis that total laminectomy would increase ASI more than would subtotal laminectomy was analyzed. Material and METHODS: This is a retrospective study of 316 patients who were treated with posterior fusion and pedicle screw fixation between 1996 and 2001. After attempts to review all 316 patients and radiologic files, 36 patients who were diagnosed with ASI were carefully reviewed, including follow-up periods of 2-8 years. The medical records were carefully reviewed for recurrence of low back pain or neurologic symptoms after a period of postoperative relief, and the radiologic files were evaluated to determine instability. All patients had undergone single-level or multilevel instrumented posterior lumbar interbody fusion for intractable pain related to degenerative conditions of the spine. RESULTS: Patients over the age of 60 were at a higher risk of developing clinical ASI however,fusion length, level and gender were not associated with ASI. The ASI was noted to occur most commonly in the cranial segment prior to fusion. CONCLUSIONS: This study revealed more frequent ASI after total laminectomy than after subtotal laminectomy, especially in elderly patients. The ideal procedure will be one combining maximal canal and foraminal decompressions with minimal resection of bony structures and supporting ligaments.
Aged ; Follow-Up Studies ; Humans ; Laminectomy ; Ligaments ; Low Back Pain ; Medical Records ; Neurologic Manifestations ; Pain, Intractable ; Recurrence ; Retrospective Studies ; Spine

BACKGROUND: Epilepsy affects an individual's ability to work as well as their daily activities. Patients with epilepsy have difficulties in finding and maintaining jobs, and they may not have opportunities to perform adequately. Therefore, evaluation of work-fitness is important for patients with epilepsy. In this report, the authors reviewed a case of epilepsy and discussed aspects of the case for evaluation of work-fitness. CASE REPORT: A 43-year-old man with epilepsy visited the hospital for evaluation of work-fitness. His job consisted of forklift driving and crane operation using a remote control. As a seizure attack could threaten worker's safety, we recommended a job change. The employer refused to approve a job change due to the company's circumstances, so we recommended several conditions, including continuous medication, use of protective equipment, restriction of night-shift work, restriction of strenuous exercise, and profound sleep. An epilepsy event occurred during the follow-up period, prompting his company to evaluate his work. There were frequent movements of forklift operations and workers in the workplace, so we recommended restriction of forklift driving and a job change if possible. As a result, the employer changed his job and we recommended "capable of performing work without any conditions". CONCLUSION: For evaluation of work-fitness in patients with epilepsy, adequate job analysis, assessment of patient's medical conditions, and interviews of coworker and employers should be conducted. It is also important to let the employer make the best decision in terms of the patient's health and coworker's safety.
Adult ; Epilepsy ; Follow-Up Studies ; Humans ; Linear Energy Transfer ; Seizures ; Work Capacity Evaluation

OBJECTIVES: To reveal the influence of job stress change on body mass index (BMI) and waist circumference in white-collar male workers. METHODS: A total of 277 male workers in a Korean R&D company were enrolled between 2008 and 2010. Baseline and follow-up data were collected with structured self-administered questionnaires and anthropometric measurements by nurses. The questionnaire survey included general and work-related characteristics and the Korean Occupational Stress Scale-Short Form (KOSS-SF). The job stress scores in each examination were dichotomized at the median values for the Korean workers and categorized into four groups as follows: Group I: Both low job stress (2008, 2010), Group II: High job stress (2008) & low job stress (2010), Group III: Low job stress (2008) & high job stress (2010), Group IV: Both high job stress (2008, 2010). Multiple logistic regression modeling was used to determine the influence of job stress change on BMI and waist circumference. RESULTS: The adjusted odds ratio for the change in waist circumference above the 75th percentile for Group IV in 'job demand' increased more than in Group I (OR = 2.54 95% CI=1.06~5.55). Also, Group IV in 'job demand' has higher odds ratio for change in BMI above the 75th percentile than Group I (OR=2.25 95% CI=1.01~5.00). Adjusted odds ratios comparing Group II to Group I for the change in waist circumference above the 75th percentile were 0.36 (95% CI=0.15~0.87) in 'inadequate social support', 0.12 (95% CI=0.02~0.98) in 'lack of reward', 0.25 (95% CI=0.08~0.80) in 'total score', respectively. CONCLUSIONS: These results suggest that sustained high job control is a risk factor for abdominal obesity and weight gain. Also, diminished job stress has a negative influence on change in abdominal obesity. Further studies are required to establish job stress intervention plans.
Body Mass Index ; Follow-Up Studies ; Humans ; Logistic Models ; Longitudinal Studies ; Male ; Obesity, Abdominal ; Odds Ratio ; Questionnaires ; Risk Factors ; Waist Circumference ; Weight Gain

Gastrointestinal (GI) fistulas are frequently very serious complications that are associated with high morbidity and mortality. GI fistulas can cause a wide array of pathophysiological effects by allowing abnormal diversion of the GI contents, including digestive fluid, water, electrolytes, and nutrients, from either one intestine to another or from the intestine to the skin. As an alternative to surgery, recent technical advances in interventional radiology and percutaneous techniques have been shown as advantageous to lower the morbidity and mortality rate, and allow for superior accessibility to the fistulous tracts via the use of fistulography. In addition, new interventional management techniques continue to emerge. We describe the clinical and imaging features of GI fistulas and outline the interventional management of GI fistulas.
Drainage ; Gastric Fistula/diagnosis/radiography/*therapy ; Humans ; Intestinal Fistula/diagnosis/radiography/*therapy ; Punctures ; *Radiography, Interventional