BACKGROUND: The growth of elderly population increased the need for oral health care. Elderly patients with poor teeth alignment needs more attention with orthodontic treatment METHODS: Elderly patients visiting department of orthodontics, Kangdong Sacred Heart Hospital between 2000-2004 were treated with fixed appliances in one or both dental arches. Treatment plans were different from than that of younger patients and included uncommon and strategic removals of teeth and prosthesis. RESULTS: There was decrease in orthodontic treatment forces with increasing age, and the observation made from this study was favorable in the patients' as well as in the orthodontist's, point of view. It was possible to move the remaining teeth considerably, and the retention was made with various fixed appliances. CONCLUSIONS: Orthodontic treatment is not limited by patient age. However, it is wise not to extend treatment goals too far beyond the patients' objective needs
Aged* ; Dental Arch ; Heart ; Humans ; Oral Health ; Orthodontics ; Prostheses and Implants ; Tooth

BACKGROUND AND OBJECTIVES: Medial orbital wall fractures are seen in association with fractures of the orbital floor or more complex bony disruptions. It is important to diagnose and manage medial orbital wall fractures as early as possible, because of the possibility of functional orbital damage later. In this study, fractures were divided into the following types based on location and severity of injury according to Nolasco and Mathog: type I (confined to the medial orbital wall), type II (medial orbital wall continuous with floor, type III (medial orbital wall with floor-malar fractures), and type IV (medial orbital wall and complex midfacial injuries). MATERIALS AND METHODS: We reviewed 22 cases of medial orbital wall fractures according to the classification of Nolasco and Mathog at Soonchunhyang University Chunan Hospital. RESULTS: 1) Types of fractures observed were type I (9 cases), type II (10 cases), type III (2 cases), and type IV (1 case). 2) The most common age groups were the thirties and the fourties. The male-to-female ratio was 3:1, and more injuries were found at the left orbit. 3) Assault was the most common cause, as observed in 10 of 22 cases (45.5%), and types III and IV injuries only occurred in falls. 4) Diplopia was the most common symptom, as in 15 of 22 cases (68.2%). Ecchymosis and periorbital swelling were more common with type I; diplopia was more common with type II. 5) Type I fractures were generally explored through intranasal approach, whereas the other types were commonly treated with subciliary or Caldwell-Luc approach. SUMMARY: Medial orbital wall fractures were more common in type I and II, the male, and the left side. Commonly, type I fractures caused ecchymosis and periorbital swelling and were treated with conservative treatment. In most cases, type II fractures caused diplopia and were treated with surgery 1 or 2 weeks after trauma.
Chungcheongnam-do ; Classification ; Diplopia ; Ecchymosis ; Humans ; Male ; Orbit* ; Orbital Fractures

Patients who have repaired cleft lip and palate generally undergo restriction of maxillary growth. Concave facial profile is often exhibited with relatively normalized mandible. Horizontal and sagittal deficiency of the maxilla could cause anterior and posterior crossbites. In growing patients, orthodontic and orthopedic treatment is acceptable with maxillary expansion and protraction. However, surgical approach has to be accompanied with orthodontic treatment in skeletally matured patients. We used SARPE and BSSRO to expand the constricted maxilla and retract the mandible in a patient who had cleft palate repaired in infancy. Through SARPE, orthodontic treatment and BSSRO, we sufficiently expanded the maxillla and improved facial profile.
Cleft Lip ; Cleft Palate ; Humans ; Malocclusion ; Mandible ; Maxilla ; Orthopedics ; Palatal Expansion Technique ; Palate

Patients who have repaired cleft lip and palate generally undergo restriction of maxillary growth. Concave facial profile is often exhibited with relatively normalized mandible. Horizontal and sagittal deficiency of the maxilla could cause anterior and posterior crossbites. In growing patients, orthodontic and orthopedic treatment is acceptable with maxillary expansion and protraction. However, surgical approach has to be accompanied with orthodontic treatment in skeletally matured patients. We used SARPE and BSSRO to expand the constricted maxilla and retract the mandible in a patient who had cleft palate repaired in infancy. Through SARPE, orthodontic treatment and BSSRO, we sufficiently expanded the maxillla and improved facial profile.
Cleft Lip ; Cleft Palate ; Humans ; Malocclusion ; Mandible ; Maxilla ; Orthopedics ; Palatal Expansion Technique ; Palate

PURPOSE: To compare the treatment results of triscaphe and scaphocapitate arthrodesis in Lichtman's stage III Kienbock's disease. MATERIALS AND METHODS: Among 25 cases of Kienbock's disease (Lichtman's stage III), who were followed up more than 1 year after surgery from 1997 March to 2005 March, 15 cases of scaphocapitate and 10 cases of triscaphe arthrodesis were reviewed. The average age was 42.6 and the mean follow-up period was 33 months. The clinical and radiology results were analyzed before surgery and at the last follow-up. RESULTS: In the clinical assessments, there was good pain relief after each procedure and there was a similar limitation of the carpal range of motion before and after surgery. The radiology assessments revealed no difference between the two arthrodeses according to the carpal height ratio and lunate index. Regarding complications, there were 4 cases with a scaphocapitate including 1 nonunion and 4 cases with triscaphe arthrodesis including 2 superficial infections. CONCLUSION: The scaphocapitate arthrodesis is a technically simple, easy reducible to the anatomical position and produces similar clinical and radiology results to triscaphe arthrodesis. Overall, scaphocapitate arthrodesis appears to be an effective method for treating Lichtman's stage III Kienbock's disease.
Arthrodesis* ; Follow-Up Studies ; Osteonecrosis* ; Range of Motion, Articular

Varicella-zoster virus (VZV) is a causative agent for chickenpox in primary infection and shingles after reactivation from latency. Both varicella and zoster can be prevented by live attenuated vaccines, but the molecular mechanism of attenuation is not clearly understood. In this study, the genome sequences of three varicella vaccine strains were analyzed for the genetic diversity including single nucleotide polymorphism (SNP) and genetic polymorphism. A total of 38 SNPs were identified including 29 substitutions and 9 insertion/deletions. The number of genetically polymorphic sites (GPS) was highest in Varivax and lowest in Varilrix. GPS in the R region including R1, R2, and R3 appeared to be responsible for the genetic polymorphisms in the open reading frame (ORF) 11, 14, and 22 in all three vaccine strains. A relatively large number of GPS were observed in ORF31, 55, and 62, which are known to be essential for virus replication, suggesting that the attenuation of the vaccine strains may be attributed by the diversity of these genes.

Lymphangioleiomyomatosis is a rare disease which afflicts young women of childbearing age. We experienced a 32-year-old female who was admitted because of worsening exertional dyspnea after hormonal therapy with Clomifen for five months and intermittent hemoptysis. Chest PA showed diffuse ground glass appearance with some reticular infiltrations. High resolution CT scan showed multiple small thin walled cysts distributed homogeneously throughout the entire lung. Pulmonary function test showed characteristic obstructive pattern despite the restrictive interstitial pattern of chest radiography. Thoracoscopic lung biopsy specimen showed abnormal proliferation of smooth muscle cells in the walls of lymphatic vessels, bronchioles, and pulmonary vessels typical of pulmonary lymphangioleiomyomatosis. Hormonal therapy with medroxyprogesterone was initiated.
Adult ; Biopsy ; Bronchioles ; Clomiphene* ; Dyspnea* ; Female ; Glass ; Hemoptysis ; Humans ; Lung ; Lymphangioleiomyomatosis ; Lymphatic Vessels ; Medroxyprogesterone ; Myocytes, Smooth Muscle ; Radiography ; Rare Diseases ; Respiratory Function Tests ; Thorax ; Tomography, X-Ray Computed

The emerging pathogen, group C rotavirus (RVC) has been reported to cause acute diarrhea. But there was the limitation on the detection and monitoring for the absence of rapid sensitive diagnosis system. For the molecular biology study and diagnostic system development, we could detect porcine RVC by reverse transcriptase PCR (RT-PCR) analyses from 60 diarrheal disease porcine stool samples. VP6 full length RT-PCR product (CA-2 RVC, 1352 bp) was cloned and compared the nucleotide and deduced amino acid sequences with those of previously reported other porcine, human, and bovine rotavirus group A, B and C strains. Analyses data showed >82% homology on the nucleotide sequences and >90% homology on the deduced amino acid sequences with other RVCs. Recombinant baculovirus was prepared with cloned PCR product corresponding to VP6 coding sequence (CDS) (position 22~1206) into BaculoDirect(TM) C-term linear DNA, and used for the transfection of insect cells. The polyclonal antibody was produced from mice with purified recombinant VP6 and confirmed with western blot. Both of VP6 antigen and antibody, are useful for the development of rapid diagnostic system against RVC.
Amino Acid Sequence ; Animals ; Antibody Formation ; Baculoviridae ; Base Sequence ; Blotting, Western ; Clinical Coding ; Clone Cells ; Diarrhea ; DNA ; Humans ; Insects ; Mice ; Molecular Biology ; Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Rotavirus ; Transfection

No abstract available.
Cerebral Infarction ; Female ; Fibromuscular Dysplasia ; Humans ; Hypertension, Renovascular

Skeletal anterior open bite is a difficult problem to correct in orthodontic treatment. To treat adult patients who have skeletal anterior open bite, we considered two methods. Combination treatment of orthodontics & surgery and camouflage orthodontic treatment. In adults, treatment of severe skeletal anterior open bite consists mainly of surgically repositioning the maxilla or the mandible. However, camouflage therapy is often the treatment of choice for skeletal open bite patients who have mild to moderate skeletal discrepancies when growth modification is no longer possible. But excellent results generally require careful coordination of the orthodontic and surgical phases of treatment. This is a case report of a skeletal anterior open bite patients who were treated with orthodontic treatment and orthognathic surgery. First case was diagnosed as skeletal class I malocclusion & bimaxillary protrusion with anterior open bite, and finally treatment ended for removal of open bite with orthodontic procedure and bimaxillary anterior segmental osteotomy surgery. Second case was diagnosed as skeletal class II malocclusion with open bite & mandibular retrusion, and was treated with only camouflage orthodontics because she feared to have a surgery. In a regular follow up visit after debonding we proposed to the patient advanced genioplasty, and in her agreement her facial esthetics was improved through the surgery.
Adult ; Esthetics ; Follow-Up Studies ; Genioplasty ; Humans ; Malocclusion ; Mandible ; Maxilla ; Open Bite ; Orthodontics ; Orthognathic Surgery ; Osteotomy ; Retrognathia