PURPOSE: This study was conducted to evaluate the efficacy of 2 percutaneous breast biopsy techniques for diagnosing microcalcification: stereotactic Vacuum-assisted biopsy (VAB) and needle localization VAB. METHODS: Between November 2002 and September 2007, 138 patients underwent percutaneous breast biopsy for microcalcification. Of these, 59 patients underwent needle localization VAB and 79 patients underwent stereotactic VAB with using a prone-table mammographic unit, respectively. Patients with focally clustered microcalcification underwent stereotactic VAB. Patients with diffuse or deep seated microcalcification and patients with small breast underwent needle localization VAB. We retrospectively reviewed the characteristics of the lesions and the percutaneous biopsy results for all the cases. RESULTS: Percutaneous biopsy was successful in 135 cases (97.8%). Of the 135 successfully performed cases, 34 cases (25.2%) were malignant and there were 4 (11.8%) underestimations. For the stereotactic VAB group, 13 of the successfully performed 76 cases (17.1%) were malignant and there were 2 (15.4%) underestimations. In needle localization VAB group, 21 (36.6%) of the 59 cases were malignant and there were 2 (9.5%) underestimations. There was no major complication in all the cases. CONCLUSION: With using stereotactic VAB and needle localization VAB, we can biopsy accurately and safely in almost all cases with leaving only minimal scar. So, percutaneous biopsy can be considered as a substitute for surgical biopsy for microcalcification of the breast.
Biopsy ; Breast ; Cicatrix ; Humans ; Needles ; Retrospective Studies

PURPOSE: This study was conducted to evaluate the efficacy of 2 percutaneous breast biopsy techniques for diagnosing microcalcification: stereotactic Vacuum-assisted biopsy (VAB) and needle localization VAB. METHODS: Between November 2002 and September 2007, 138 patients underwent percutaneous breast biopsy for microcalcification. Of these, 59 patients underwent needle localization VAB and 79 patients underwent stereotactic VAB with using a prone-table mammographic unit, respectively. Patients with focally clustered microcalcification underwent stereotactic VAB. Patients with diffuse or deep seated microcalcification and patients with small breast underwent needle localization VAB. We retrospectively reviewed the characteristics of the lesions and the percutaneous biopsy results for all the cases. RESULTS: Percutaneous biopsy was successful in 135 cases (97.8%). Of the 135 successfully performed cases, 34 cases (25.2%) were malignant and there were 4 (11.8%) underestimations. For the stereotactic VAB group, 13 of the successfully performed 76 cases (17.1%) were malignant and there were 2 (15.4%) underestimations. In needle localization VAB group, 21 (36.6%) of the 59 cases were malignant and there were 2 (9.5%) underestimations. There was no major complication in all the cases. CONCLUSION: With using stereotactic VAB and needle localization VAB, we can biopsy accurately and safely in almost all cases with leaving only minimal scar. So, percutaneous biopsy can be considered as a substitute for surgical biopsy for microcalcification of the breast.
Biopsy ; Breast ; Cicatrix ; Humans ; Needles ; Retrospective Studies

No abstract available.
Tissue Expansion*

No abstract available.

We present a patient who developed recurrent angina after coronary artery bypass grafting (CABG). Myocardial single-photon emission computed tomography (SPECT) demonstrated deterioration in the myocardial perfusion, and coronary angiography revealed an overgrown side branch of the grafted left internal thoracic artery (ITA); otherwise, there were no significant changes compared with previous imaging studies obtained after the CABG. After percutaneous embolization of the grafted left ITA side branch, the angina was resolved and myocardial SPECT showed improved perfusion.
Arteries* ; Coronary Angiography ; Coronary Artery Bypass ; Embolization, Therapeutic ; Humans ; Mammary Arteries* ; Myocardial Ischemia* ; Perfusion ; Tomography, Emission-Computed ; Tomography, Emission-Computed, Single-Photon ; Transplants*

The blink reflex is an electrically induced glabella response that has long been used in clinical neurology. The blink reflex is now known to be a polysynaptic reflex with an afferent arc through sensory fibers of the trigerminal nerve and with an c,fferent arc through the motor fibers of the facial nerve. This study was performed to determine the relationship of latency and amplitude to ethnic groups sex and age and to obtain the normal data of korean in the blink reflex(BR) and direct facial nerve stimulation test(DFNS). BR and DFNS were recorded in 103 normal korean adults that consisted of 52 men and 51 women and the age ranged 22 to 77 years. The results are as follows: (1) the Rl wave was more stable than R2 and contralateral R2 wave, (2) there seerns to be no significant difference of latency and amphtude between ethnic groups, (3) the latency of Rl wave was shorter and the amplitude of CMAP was larger m men compared with women and (4) the latency of Rl wave was increased by aging.
Adult* ; Aging ; Blinking* ; Ethnic Groups ; Facial Nerve* ; Female ; Humans ; Male ; Neurology ; Reflex

Recent studies on T cell immunology have been instrumental in developing therapies to overcome cancer immune escape, and immune checkpoint inhibitors have emerged as one of the most promising therapeutic tools in advanced cancer patients. Immune checkpoint inhibitors (ICPIs) are monoclonal antibodies that modulate the effects of immune checkpoints. These include cytotoxic T lymphocyte antigen 4 and programmed cell death protein 1, which are co-inhibitory signals responsible for immune suppression. Despite their clinical benefits, ICPIs behave as general immune activators, exerting to several toxic effects called immune-related adverse events attributed to organ-specific inflammation. Here, we review ICPI toxicities, highlighting the importance of their early identification and proper management.
Adrenal Cortex Hormones ; Allergy and Immunology ; Antibodies, Monoclonal ; Cell Death ; CTLA-4 Antigen ; Humans ; Inflammation ; United Nations

Purpose: To understand the effects of datasets with various parameters on pretrained network performance, the generalization capacity of the artificial neural network for myelin water imaging (ANN-MWI) is explored by testing datasets with various scan protocols (i.e., resolution and refocusing RF pulse shape) and types of disorders (i.e., neuromyelitis optica and edema). Materials and Methods: ANN-MWI was trained to generate a T2 distribution, from which the myelin water fraction value was measured. The training and test datasets were acquired from healthy controls and multiple sclerosis patients using a multiecho gradient and spin-echo sequence with the same scan protocols. To test the generalization capacity of ANN-MWI, datasets with different settings were utilized.The datasets were acquired or generated with different resolutions, refocusing pulse shape, and types of disorders. For all datasets, the evaluation was performed in a white matter mask by calculating the normalized root-mean-squared error (NRMSE) between the results from the conventional method and ANN-MWI. Additionally, for the patient datasets, the NRMSE was calculated in each lesion mask. Results: The results of ANN-MWI showed high reliability in generating myelin water fraction maps from the datasets with different resolutions. However, the increased errors were reported for the datasets with different refocusing pulse shapes and disorder types. Specifically, the region of lesions in edema patients reported high NRMSEs. These increased errors indicate the dependency of ANN-MWI on refocusing pulse flip angles and T 2 characteristics. Conclusion This study proposes information about the generalization accuracy of a trained network when applying deep learning to processing myelin water imaging.

A series of 61 cases of primary hemifacial spasm have been evaluated by means of blink reflex and needle electromyography and their result compared with unaffected site. The R1 and R2 response and late acti-ity. After activity in blink reflex. And electrical activity in EMG at rest were observed. The results of study were as in the followings: 1) The arnplitude of large R1 and R2 responses were increased in affected side in contrast to unaffected side. 2) late activity(72.2%) and after activity(83.6%) were observed in only affected side at rela-ti-ely Iong duration, as well as regular interval spontaneous repetivive discharges in EMG at rest. This result of large R1 and R2 responses could be compatible with ephaptic ransmission, but late activity, after activity, and spontaneous repetitive MUPs could be explained hyperexcitability of the facial motor nucleus rather than autoexcitation of peripheral facial nerve. Additionally the authors thought that the use of conventional blink reflex as well as specialized blink reflex tests could be very useful for the diagnosis of hemifacial spasm and for the evaluation of it's course.
Blinking* ; Diagnosis ; Electromyography* ; Facial Nerve ; Hemifacial Spasm* ; Needles

Pregnancy-associated breast cancer is defined as that occurring during pregnancy or within 1 year after delivery. The incidence of pregnancy-associated breast cancer is 0.2% to 3.8%. Tenderness, engorgement, increased size and increased prominence of the glandular tissue during pregnancy and lactation make mammography and clinical breast examination uncomfortable for the patient and less accurate for the detection of an abnormal breast mass. Pregnancy-associated breast cancer tends to be diagnosed at a more advanced stage, with an attendant adverse prognosis, than in women who are not pregnant or lactating. So physicians should perform a thorough breast examination at the first prenatal visit and maintain a high index of suspicion for cancer. We experienced 2 cases of pregnancy-associated breast cancer patients and reported these cases with a brief review of literature.
Breast Neoplasms* ; Breast* ; Female ; Humans ; Incidence ; Lactation ; Mammography ; Pregnancy ; Prognosis