1.The Effect of Aroma Therapy on Lower Extremity Edema of Terminal Cancer Patients: A Controlled Trial.
Sung Ah KIM ; Sung Ju KIM ; Juhye CHUNG ; Soo Young LEE ; Myung Suk HAN ; Seon Hee OH ; Se Hong KIM
Korean Journal of Hospice and Palliative Care 2009;12(3):139-146
PURPOSE: This study was designed to examine the effect of aroma massage therapy on lower extremity edema of terminal cancer patients. METHODS: A total of thirty-six terminal cancer patients with lower extremity edema were divided into two groups: the aroma massage group received massage with blending oil which was applied from toes to 10 cm above the knee of the subject for 15 to 20 minutes in each turn, while the control group received sham aroma massage (applied with carrier oil only). The circumferences of the fore-foot, ankle and calf were measured before massage and 30 minutes, 2 hours, and 12 hours after massage. The blood pressure, pulse and body temperature were also measured to find the change of subject's physiologic conditions. RESULTS: There were no significant differences in blood pressure, heart rate, body temperature and lower extremity circumferences between two groups. However, edema at each site was slightly improved in the treatment group after the aroma massage therapy, compared to baseline data (P<0.05). In addition, the reduction of lower extremity circumference was maximal at 2 hours in foot, 30 min in right ankle and 12 hours in right calf after aroma massage therapy (P<0.05). CONCLUSION: Our results suggest that aroma massage therapy is not effective on the lower extremity edema of terminal cancer patients.
Animals
;
Ankle
;
Aromatherapy
;
Blood Pressure
;
Body Temperature
;
Edema
;
Foot
;
Heart Rate
;
Hospices
;
Humans
;
Knee
;
Lower Extremity
;
Massage
;
Salicylamides
;
Toes
2.Systemic Amyloidosis after Operation of Gastric Cancer.
Seung Nam CHOI ; Hun JUNG ; Se Jung OH ; Wook KIM ; Hae Myung JEON ; Ah Won LEE
Journal of the Korean Surgical Society 2004;66(4):342-346
Systemic amyloidosis after gastric cancer surgery is a very rare phenomenon. Less than ten such cases have been reported in the international literature. Although systemic amyloidosis has been reported to be associated with lymphoma, multiple myeloma, and renal cell carcinoma, its association with gastric cancer remains unclear. We report a case of a 64-year-old male who developed systemic amyloidosis 24 months after a Billroth-I gastrectomy for gastric cancer, and provide a brief review of the literature.
Amyloidosis*
;
Carcinoma, Renal Cell
;
Gastrectomy
;
Humans
;
Lymphoma
;
Male
;
Middle Aged
;
Multiple Myeloma
;
Stomach Neoplasms*
3.The Correlation between Bispectral Index andHemodynamic Responses with Skin Incision duringSevoflurane Anesthesia in Children.
Ah Young OH ; Chong Sung KIM ; Kwang Suk SE ; Hee Soo KIM
Korean Journal of Anesthesiology 2007;53(6):S26-S30
BACKGROUND: It is well documented that BIS reflects the level of sedation but conflicting results exist about whether BIS can reflect the depth of anesthesia. We intended to identify this issue by investigating the correlation between the pre-incision bispectral index (BIS) values and the hemodynamic responses to skin incision during sevoflurane-N2O anesthesia in children. METHODS: In total, 117 ASA physical status I or II pediatric patients, aged 6 mo-12 yr, were enrolled. After induction and intubation with thiopental, rocuronium, sevoflurane and N2O, patients were randomly allocated to one of the four end-tidal sevoflurane concentrations (ETsevo); 2.0, 2.5, 3.0, and 3.5 %; with 60% N2O. The ETsevo was maintained constant for more than 15 min before and 5 min after skin incision. BIS, heart rate (HR), and systolic arterial pressure (SAP) before and after skin incision were recorded. RESULTS: Although there were no correlation between pre-incision BIS and change in BIS, SAP, and HR (Pearson's coefficient -0.120, -0.102, and -0.080, respectively), there were correlations between changes of BIS and changes in SAP and HR (Pearson's coefficient 0.318 and 0.309, respectively, P < 0.05). CONCLUSIONS: There was a correlation between the change of BIS, but not BISpre, and change in hemodynamic variables with skin incision during sevoflurane anesthesia in children.
Anesthesia*
;
Arterial Pressure
;
Child*
;
Heart Rate
;
Hemodynamics
;
Humans
;
Intubation
;
Skin*
;
Thiopental
4.Clinical Factors Associated with Severity of Post-stroke Dysphagia.
Juyong KIM ; Byung Mo OH ; Goo Joo LEE ; Seung Ah LEE ; Se Woong CHUN ; Tai Ryoon HAN
Brain & Neurorehabilitation 2011;4(2):116-120
OBJECTIVE: To describe factors associated with the severity of post-stroke dysphagia. METHODS: We reviewed retrospectively medical records of patients having dysphagia following stroke in Seoul National University hospital from April 2002 through Dec 2009. A total of 578 patients (male and female, 331 and 247) were included. The following parameters were recorded and analyzed: patient's sex, age, type of stroke, onset of dysphagia, location of lesion and the American Speech-Language-Hearing Association National Outcome Measurement System Swallowing Scale (ASHA NOMS). Using Binary logistic regression and multiple regression analysis, the relationship between dysphagia severity and other factors were analyzed. RESULTS: Their average duration between onset of stroke and the date of videofluoroscopic swallowing study (VFSS) was 32.3 +/- 18.4 days. Patients with hemorrhagic stroke (172 patients, ASHA 4.06 +/- 1.98) showed poorer swallowing function than those with ischemic stroke (406 patients, ASHA 4.49 +/- 2.02, p=0.013). Binary logistic regression analysis showed that patients who had longer duration from onset to the first study, hemorrhagic stroke, bilateral lesion and older age were at higher risk for dysphagia requiring non-oral supplements (p=0.031, 0.039, 0.042, and 0.043, respectively). Multiple regression analysis revealed that longer duration from onset to study, older age and hemorrhagic stroke were associated with the lower ASHA NOMS (p=0.006, 0.009 and 0.021, respectively). Bilateral lesion, sex, history of previous stroke and involvement of the brainstem, however, were not significant factors. CONCLUSION: Hemorrhagic stroke, longer duration from stroke onset to the initial evaluation, and older age were identified as associated factors with the poorer swallowing function after stroke. Further prospective studies will be required to evaluate the prognostic value of these characteristics.
American Speech-Language-Hearing Association
;
Brain Stem
;
Deglutition
;
Deglutition Disorders
;
Female
;
Humans
;
Logistic Models
;
Medical Records
;
Regression Analysis
;
Retrospective Studies
;
Stroke
5.Development of Food Security Measures for Korean National Health and Nutrition Examination Survey.
Kirang KIM ; Seo Ah HONG ; Sung Ok KWON ; Se Young OH
The Korean Journal of Nutrition 2011;44(6):551-561
Given that household food security issues have become the concern of the Korean society, this study aimed to develop food security measures for the Korean population. Based on the literature reviews on previously developed food security measures, the 18-item US household food security survey module (US HFSSM) was adapted. The developed food security measures was assessed by qualitative validity method. It was evaluated and modified by face validity by expert focus groups belong to university, public health center, and government agencies and by cognitive interview by 40 subjects with low household income who live in an urban community and are participants in welfare programs of local districts. Then, it was reviewed and revised by the National Institute of the Korean Language and the advisory committee for nutrition survey of Korean National Health and Nutrition Examination Survey (KNHANES). The results showed that the developed questionnaire items were well adapted by expert focus groups and general subjects, showing the feasibility of measuring food security with the developed measures although there were discrepancies in some expressions of questionnaire items between experts focus groups and general subjects. The study to assess reliability and quantitative validity of the developed food security measures should be further needed to examine its application for KNHANES.
Advisory Committees
;
Family Characteristics
;
Focus Groups
;
Food Supply
;
Government Agencies
;
Nutrition Surveys
;
Public Health
;
Surveys and Questionnaires
6.Noninvasively-determined Diastolic Stiffness is Abnormal during Exercise, but not at Rest, in Patients with Apical Hypertrophic Cardiomyopathy.
Jong Won HA ; Eui Young CHOI ; Jin Mi KIM ; Jeong Ah AHN ; Se Wha LEE ; Hye Sun SEO ; Ji Hyun LEE ; Se Joong RIM ; Jae K OH ; Namsik CHUNG
Journal of Cardiovascular Ultrasound 2007;15(3):77-81
BACKGROUDN: The ratio of mitral inflow (E) and annular velocity (E') to stroke volume (E/E'/SV) has been used as an index of diastolic elastance (Ed). However, its change during exercise has not been evaluated. We hypothesized that Ed values obtained during exercise would be abnormal in patients with apical hypertrophic cardiomyopathy (ApHCM). METHODS: Ed was measured at rest and during graded supine bicycle exercise (25 Watts, 3 minute increments) in 15 patients with ApHCM (12 male; mean age, 57 years) and in 15 age- and gender-matched control subjects. RESULTS: Ed was not significantly different at rest and during 25 W of exercise. However, Ed was significantly higher at 50 W of exercise in patients with ApHCM compared to control subjects (0.21+/-0.05 vs. 0.15+/-0.04 cm/s, p=0.0059). There was significant positive correlation between the magnitude of change in proBNP levels during exercise and the change of Ed from rest to 50 W of exercise (r2=0.69, p<0.0001). CONCLUSION: Noninvasively-determined Ed was similar at rest and during mild exercise between patients with ApHCM and control subjects. However, Ed was significantly higher during moderate exercise in ApHCM patients, suggesting a dynamic change in LV stiffness during exercise in these patients.
Cardiomyopathy, Hypertrophic*
;
Humans
;
Male
;
Stroke Volume
7.Noninvasively-determined Diastolic Stiffness is Abnormal during Exercise, but not at Rest, in Patients with Apical Hypertrophic Cardiomyopathy.
Jong Won HA ; Eui Young CHOI ; Jin Mi KIM ; Jeong Ah AHN ; Se Wha LEE ; Hye Sun SEO ; Ji Hyun LEE ; Se Joong RIM ; Jae K OH ; Namsik CHUNG
Journal of Cardiovascular Ultrasound 2007;15(3):77-81
BACKGROUDN: The ratio of mitral inflow (E) and annular velocity (E') to stroke volume (E/E'/SV) has been used as an index of diastolic elastance (Ed). However, its change during exercise has not been evaluated. We hypothesized that Ed values obtained during exercise would be abnormal in patients with apical hypertrophic cardiomyopathy (ApHCM). METHODS: Ed was measured at rest and during graded supine bicycle exercise (25 Watts, 3 minute increments) in 15 patients with ApHCM (12 male; mean age, 57 years) and in 15 age- and gender-matched control subjects. RESULTS: Ed was not significantly different at rest and during 25 W of exercise. However, Ed was significantly higher at 50 W of exercise in patients with ApHCM compared to control subjects (0.21+/-0.05 vs. 0.15+/-0.04 cm/s, p=0.0059). There was significant positive correlation between the magnitude of change in proBNP levels during exercise and the change of Ed from rest to 50 W of exercise (r2=0.69, p<0.0001). CONCLUSION: Noninvasively-determined Ed was similar at rest and during mild exercise between patients with ApHCM and control subjects. However, Ed was significantly higher during moderate exercise in ApHCM patients, suggesting a dynamic change in LV stiffness during exercise in these patients.
Cardiomyopathy, Hypertrophic*
;
Humans
;
Male
;
Stroke Volume
8.Subcutaneous sarcoidosis presenting as a suprapubic mass, acute kidney injury, and hypercalcemia.
Jeong Min KIM ; Yoon Kyeong SONG ; Seon Jin PARK ; Young Hwan HWANG ; Su Ah SUNG ; So Young LEE ; Jong Eun JOO ; Se Won OH
The Korean Journal of Internal Medicine 2014;29(4):535-538
No abstract available.
Acute Kidney Injury/diagnosis/*etiology/therapy
;
Biopsy
;
Fluid Therapy
;
Glucocorticoids
;
Humans
;
Hypercalcemia/diagnosis/*etiology/therapy
;
Male
;
Middle Aged
;
Multimodal Imaging
;
Positron-Emission Tomography
;
Renal Dialysis
;
Sarcoidosis/*complications/diagnosis/therapy
;
Subcutaneous Tissue/pathology
;
Tomography, X-Ray Computed
;
Treatment Outcome
9.Fanconi Syndrome Associated with Long-term Adefovir and Subsequent Tenofovir Therapy for Chronic Hepatitis B Infection.
Hyun Woo LEE ; June Sung LEE ; Se Won OH ; Joo Hyuk JUNG ; Min Yong PARK ; Kyung Ah KIM ; Yeon Han SONG
Korean Journal of Medicine 2016;91(2):174-178
Adefovir dipivoxil (ADV) and tenofovir disoproxil fumarate (TDF) are nucleotide analogues used to treat chronic hepatitis B (CHB) infection. Nephrotoxicity associated with the use of these medications causes Fanconi syndrome, a rare condition involving generalized dysfunction of the proximal renal tubule causing impaired reabsorption of glucose, uric acid, and phosphate. Fanconi syndrome has been previously reported in patients with human immunodeficiency virus (HIV) or HIV-CHB coinfection treated with other antiretroviral therapies. However, it is rarely reported in patients with CHB monoinfection. We observed a case of Fanconi syndrome in a 61-year-old woman with CHB monoinfection and a history of long-term ADV therapy (42 months), followed by TDF treatment for 9 months. She presented with ankle pain and a tingling sensation in both lower extremities. Laboratory tests revealed hypokalemia, hypocalcemia, hypophosphatemia, hypouricemia, proteinuria, and glycosuria. This case illustrates the importance of recognizing Fanconi syndrome associated with nucleotide analogue treatment and the need to carefully observe symptoms and monitor renal function in these patients.
Ankle
;
Coinfection
;
Fanconi Syndrome*
;
Female
;
Glucose
;
Glycosuria
;
Hepatitis B, Chronic*
;
Hepatitis, Chronic*
;
HIV
;
Humans
;
Hypocalcemia
;
Hypokalemia
;
Hypophosphatemia
;
Kidney Tubules, Proximal
;
Lower Extremity
;
Middle Aged
;
Proteinuria
;
Sensation
;
Uric Acid
10.Cardiac Magnetic Resonance Predictor of Ventricular Function after Surgical Coronary Revascularization.
Ho Young HWANG ; Sang Yoon YEOM ; Jae Woong CHOI ; Se Jin OH ; Eun Ah PARK ; Whal LEE ; Ki Bong KIM
Journal of Korean Medical Science 2017;32(12):2009-2015
We evaluated echocardiographic changes of left ventricular (LV) function in coronary artery bypass grafting (CABG) patients with LV dysfunction, and examined cardiac magnetic resonance (CMR) parameters associated with improved LV function. Seventy-seven CABG patients presenting with decreased LV ejection fraction (LVEF, ≤ 35%) and who underwent preoperative gadolinium-enhanced CMR were enrolled. A 16-segment model was used to analyze CMR imaging. A viable myocardial segment was defined as ≤ 50% transmural extent of late gadolinium enhancement. Serial echocardiographic examinations were performed preoperatively, pre-discharge (median 6 days), and during postoperative year 1 (median 11 months) in 70 patients. Predictors of absolute increase in LVEF (≥ 5%) and proportional changes in LVEF were analyzed. Serial echocardiography demonstrated that LVEF measured 28.6% ± 5.4% preoperatively, 31.5% ± 8.0% median 6 days, and 42.1% ± 10.5% median 11 months postoperatively. Absolute increase of LVEF was observed in 27 patients at pre-discharge and in 24 patients by median 11 months. Proportional changes in LVEF at postoperative median 6 days and 11 months were 14% ± 28% and 57% ± 45%, respectively. The median number of viable myocardial segments was 14 (range, 9–16) in the 16 segment CMR model. Multivariable models demonstrated that the median number of overall viable myocardial segments (≥ 14) in preoperative CMR was associated with absolute increase (P = 0.046) and proportional changes (P = 0.005) in LVEF. In conclusion, the number of viable myocardial segments (≥ 14) in preoperative CMR predicted LV function improvement after CABG in patients with LV dysfunction.
Coronary Artery Bypass
;
Echocardiography
;
Gadolinium
;
Humans
;
Ventricular Dysfunction
;
Ventricular Function*