No abstract available.
Diagnosis* ; Leptospirosis* ; Scrub Typhus*

In the Department of Communicable Diseases Hospital 108, 41 patients with srub typhus were diagnosed by Weil-Felix assay and dipsticks ELISA(+) were treated. Among them 22 by chloramphenicol 50mg/kg daily and 19 by doxycycline 200mg/daily in 7 days consecutively. Clinically, the common symptoms of the disease were prolonged fever (100%) in combining with head ache 100%, muscle pain 78.4%, erythema 34.7%. Doxycycline and chloramphenicol were the most efficient medicine.
Diagnosis ; Therapeutics ; Scrub Typhus

No abstract available.
Diagnosis* ; Exanthema* ; Lymphadenitis* ; Scrub Typhus*

Linear discriminant analysis method basing on genetic algorithms was used to find out the role of clinical symptoms for taking differential diagnosis between typhoid fever and scrub typhus. Clinical records of 526 patients suffering from one of those diseases were used as input data for algorithms. The results showed that the differential value of symptoms are as follows: roseola (4 points), infectious constitution (2 points), drum belly (2 points), ingestive disorder (1 points), decrease of white-blood cell count (1 point), congestion (-2 points), enlarge of lymph node (- 2 points), erythematous eruption (-3 points), eschar (-5 points). The diagnostic rule are a follows: total point >=3: typhoid fever, between 0 and 2 points: suggestion of typhoid fever, total point <=-3: scrub typhus, between o and -2 points: suggestion of scrub typhus. To re-test on 50 patients of those 526 patients randomly, the accuracy rate of this rule is at least 98%.
Typhoid Fever ; Scrub Typhus ; diagnosis ; Algorithms

No abstract available.
Diagnosis* ; Polymerase Chain Reaction* ; Scrub Typhus*

No abstract available.
Diagnosis* ; Polymerase Chain Reaction* ; Scrub Typhus*

In this study, we report the first clinically identified case of severe fever with thrombocytopenia syndrome (SFTS) in a 73-year old man from Jeju Island, South Korea. Although his initial manifestation suggested tsutsugamushi disease with cutaneous lesion, later the patient presented with symptoms characteristic of SFTS. Despite intensive medical therapies upon the clinical diagnosis of SFTS, patient's condition rapidly deteriorated. SFTS is a fatal disease that requires early diagnosis and appropriate supportive treatment.
Diagnosis ; Early Diagnosis ; Fever* ; Humans ; Korea ; Scrub Typhus ; Thrombocytopenia*

A case of 76-years-old male patient with nasal bleeding as the first symptom in our hospital, who was finally diagnosed as tsutsugamushi disease. This old man was bited by insect in farmland 2 days before the symptom occurred. PE: Left thigh and right buttock have eschar, with splenomegaly. Routine blood test: WBC (decrease) 3.9 x 10(9)/L, RBC (decrease) 3.86 x 10(9)/L, PLT (decrease) 41 x 10(9)/L, HGB (decrease) 117 g/L; Chest CT: lung interstitial pneumonia, a small amount of bilateral pleural effusion. Oxk-ag 1:320. The patient was discharged after treatment with chloramphenicol for 8 days.
Aged ; Epistaxis ; diagnosis ; etiology ; Humans ; Male ; Scrub Typhus ; complications ; diagnosis

Tsutsugamushi disease is an acute infectious rickettsial disease caused by the intracellular parasite Orientia tsutsugamushi. Due to its variety of clinical signs, this disease is often misdiagnosed. This article examines a total of 4 patients who visited our clinics with fever and sore throat. 3 of them had body temperature of 39.5 Celsius degrees when admitted. The characteristic black eschar occurred on 4 of them. Lymphadenopathy occurred on 2 of them. Cough occurred on 1 of them. Lab tests showed that 3 of them had Leukocytosis, 1 of them had increased bronchovascular markings, and 3 of them had Weil-Felix test positive. After admission, all patients, who were confirmed of diagnosis of tsutsugamushi disease instead of tonsillitis, received the comprehensive treatment and cured afterwards.
Diagnostic Errors ; Humans ; Orientia tsutsugamushi ; Pharyngitis ; etiology ; Scrub Typhus ; complications ; diagnosis ; Tonsillitis ; diagnosis

In this study, new real-time PCR method based on the groEL gene was developed and investigated. Four spotted fever group (SFG) strains, four typhus group (TG) strains, and four scrub typhus group (STG) strains were easily differentiated as a distinct entity. This PCR assay was applied to detect Rickettsia DNA from 100 ticks. Twelve Haemaphysalis longicornis ticks were found positive and identified as spotted fever group Rickettsia. This real-time PCR method could simultaneously perform the rapid identification of rickettsiae and the differential diagnosis of SFG, TG, and STG in a single reaction.
Diagnosis, Differential ; DNA ; Fever ; Polymerase Chain Reaction ; Real-Time Polymerase Chain Reaction ; Rickettsia ; Scrub Typhus ; Ticks ; Typhus, Epidemic Louse-Borne