1.Accuracy of the daily dengue severity score in assessing disease severity in children
Mary Ann G. Abella ; Belle M. Ranile
Pediatric Infectious Disease Society of the Philippines Journal 2024;25(2):69-79
BACKGROUND
Dengue is a global health concern, particularly in tropical regions such as the Philippines. In 2019,Cebu City reported the highest number of dengue cases in Central Visayas with 3,290 cases and 20 deaths, an 11.8% increase compared to 20181 . To help predict disease outcomes and provide timely management, a scoring system, the Daily Dengue Severity Score (DDSS)² was utilized.
OBJECTIVETo determine the clinicodemographic profile of dengue patients, determine the accuracy of the DDSS in assessing disease severity, and determine a cut off score that suggests severe dengue.
METHODSPatients 1 month to 18 years admitted for dengue at Perpetual Succour Hospital from January 2018 to December 2020 were included. Cases were classified as Dengue without Warning Signs, Dengue with Warning Signs, and Severe Dengue, and scored using the DDSS. Statistical analysis used were Geometric mean and Area Under the Receiver Operating Characteristic (AUROC) curves to analyze the discriminative performance of the DDSS among the different disease severity states.
RESULTSOut of 327 cases, 34 were classified as Dengue without Warning Signs, 271 Dengue with Warning Signs, and 22 Severe Dengue. The highest mean DDSS was 17.7 ±14.0 at Day -4 among those with Severe Dengue, and the lowest mean DDSS was 1.1 ± 2.0 at Day +3 among those with Dengue without Warning Signs. A cut off point of 10 on Day -1 predicted subsequent Severe Dengue among patients with Dengue with Warning Signs. In 91.39% of cases, there was a significant relationship between the DDSS and dengue classification, and the higher the DDSS, the more severe the disease.
CONCLUSIONMajority of dengue patients were males, aged 8.1 to 9.2 years. DDSS showed 66.67% sensitivity, 92.86% specificity, a positive likelihood ratio of 9.3, and a cutoff of 10 is predictive of severe dengue among patients with dengue with warning signs.
Human ; Dengue ; Scoring Methods ; Research Design ; Patient Monitoring ; Monitoring, Physiologic
2.The Analysis of Exercise Therapy in Nursing Research.
Journal of Korean Academy of Nursing 2000;30(2):319-330
This study is aimed at analyzing the trend of research on the use of exercise in nursing research, through suggesting directions for future research and implementation of the various exercise therapies. Research studies were taken from dissertations and theses selected from the Academic Society Journals of nursing science, Journals from universities, medical and nursing schools, research institutes in various universities, the Central Journal of Medicine, and the New Medical Journal. The research published between 1970 and 1997 in Korea were analyzed, 51 research were selected. The research are analyzed according to: published time, source of the research, research design, subjects, sample size, dependant variables, exercise therapy, and effect of exercise therapy. The results were as follows: 1. Research on exercise therapy increased rapidly in the 1990's. At this time, 88.2% of research was published. 2. Research areas included: 54.9% non- degree research, 27.5% Doctoral theses, and 17.6% Master's theses. 3. The experimental design included: 66.7% non- equivalent control group pre-test/ post-test design and 29.4% one group pre-test/post- test design. 4. Out of the Subjects: 52.9% were patients with various health problems, and 47.1% were healthy individuals. 5. Sample size included: 52.9% with above 31 subjects, 11.8% with 11~15 and 26~30. 6. Exercise therapy was analyzed by type, intensity, frequency, duration, and period. 1) The Types: Aerobic exercise at 60.8% was the most common, active exercise for muscle strengthening and building made up 21.6%. 2) Exercise with 40~65% intensity comprised 25.5%, 70~85% with 7.8%, and no description of the intensity was 66.7%. 3) Frequency of 3~5 per week was the most common at 78.4%. 4) Duration: 15~60 minutes was the most common length of time at 76.5%. 5) Periods: More than 5 weeks at 82.3% were the most common in their categories. 7. Dependant variables: Psychological response was measured as a dependant variable in 92.2%, Cardio-pulmonary function 88.2%, Body Composition was 86.3%, Physical Response was 60.8%, Lipid Metabolism was 58.8%, Physical Strength was 49.0%, Glucose Metabolism was 25.5%, Activities of Daily Living was 17.6% and others added to be 3.9%. 8. The effect of Exercise Therapy was categorized into 'positive', 'partially positive', and 'no effect' according to dependant variables: Having a positive effect - Glucose Metabolism (93.3%), Physical Response (85.0%), Activities of Daily Living (81.8%), Psychological Response (71.6%), Lipid Metabolism (67.6%), Cardio- pulmonary Function (63.6%), Physical Strength (68.1%), and Body Composition (56.4%). The following suggestions can be made on the above findings: 1. Research findings on Exercise Therapy as a Nursing Intervention need to be described by their elements of type, intensity, frequency, duration and period. 2. Toproperly study the positive effects of Exercise Therapy, there needs to be (1) appropriate research design, (2) selection criteria for the subjects (3) contents of exercise prescription to individuals or groups (4) measurement criterion for the dependent variables. 3. Meta-analysis on exercise therapy also needs to be done to analyze and integrate the various results.
Academies and Institutes
;
Activities of Daily Living
;
Body Composition
;
Exercise
;
Exercise Therapy*
;
Glucose
;
Humans
;
Korea
;
Lipid Metabolism
;
Metabolism
;
Nursing Research*
;
Nursing*
;
Patient Selection
;
Prescriptions
;
Research Design
;
Sample Size
;
Schools, Nursing
3.The Analysis of Exercise Therapy in Nursing Research.
Journal of Korean Academy of Nursing 2000;30(2):319-330
This study is aimed at analyzing the trend of research on the use of exercise in nursing research, through suggesting directions for future research and implementation of the various exercise therapies. Research studies were taken from dissertations and theses selected from the Academic Society Journals of nursing science, Journals from universities, medical and nursing schools, research institutes in various universities, the Central Journal of Medicine, and the New Medical Journal. The research published between 1970 and 1997 in Korea were analyzed, 51 research were selected. The research are analyzed according to: published time, source of the research, research design, subjects, sample size, dependant variables, exercise therapy, and effect of exercise therapy. The results were as follows: 1. Research on exercise therapy increased rapidly in the 1990's. At this time, 88.2% of research was published. 2. Research areas included: 54.9% non- degree research, 27.5% Doctoral theses, and 17.6% Master's theses. 3. The experimental design included: 66.7% non- equivalent control group pre-test/ post-test design and 29.4% one group pre-test/post- test design. 4. Out of the Subjects: 52.9% were patients with various health problems, and 47.1% were healthy individuals. 5. Sample size included: 52.9% with above 31 subjects, 11.8% with 11~15 and 26~30. 6. Exercise therapy was analyzed by type, intensity, frequency, duration, and period. 1) The Types: Aerobic exercise at 60.8% was the most common, active exercise for muscle strengthening and building made up 21.6%. 2) Exercise with 40~65% intensity comprised 25.5%, 70~85% with 7.8%, and no description of the intensity was 66.7%. 3) Frequency of 3~5 per week was the most common at 78.4%. 4) Duration: 15~60 minutes was the most common length of time at 76.5%. 5) Periods: More than 5 weeks at 82.3% were the most common in their categories. 7. Dependant variables: Psychological response was measured as a dependant variable in 92.2%, Cardio-pulmonary function 88.2%, Body Composition was 86.3%, Physical Response was 60.8%, Lipid Metabolism was 58.8%, Physical Strength was 49.0%, Glucose Metabolism was 25.5%, Activities of Daily Living was 17.6% and others added to be 3.9%. 8. The effect of Exercise Therapy was categorized into 'positive', 'partially positive', and 'no effect' according to dependant variables: Having a positive effect - Glucose Metabolism (93.3%), Physical Response (85.0%), Activities of Daily Living (81.8%), Psychological Response (71.6%), Lipid Metabolism (67.6%), Cardio- pulmonary Function (63.6%), Physical Strength (68.1%), and Body Composition (56.4%). The following suggestions can be made on the above findings: 1. Research findings on Exercise Therapy as a Nursing Intervention need to be described by their elements of type, intensity, frequency, duration and period. 2. Toproperly study the positive effects of Exercise Therapy, there needs to be (1) appropriate research design, (2) selection criteria for the subjects (3) contents of exercise prescription to individuals or groups (4) measurement criterion for the dependent variables. 3. Meta-analysis on exercise therapy also needs to be done to analyze and integrate the various results.
Academies and Institutes
;
Activities of Daily Living
;
Body Composition
;
Exercise
;
Exercise Therapy*
;
Glucose
;
Humans
;
Korea
;
Lipid Metabolism
;
Metabolism
;
Nursing Research*
;
Nursing*
;
Patient Selection
;
Prescriptions
;
Research Design
;
Sample Size
;
Schools, Nursing
4.The Quality of Reporting of Randomized Controlled Trials in Korean Medical Journals Indexed in KoreaMed: Survey of Items of the Revised CONSORT Statement.
Ye Won HWANG ; Kyung Woo LEE ; In Hong HWANG ; Soo Young KIM
Journal of the Korean Academy of Family Medicine 2008;29(4):276-282
BACKGROUND: The revised Consolidated Standards for Reporting of Trials (CONSORT) were developed to improve the reporting of Randomized Controlled Trials. We studied to survey the extent to which RCTs report items included in the revised CONSORT recommendations. METHODS: A descriptive survey of RCTs enrolled in 2005 at KoreaMed, which is a representative database in Korea was done. The main outcome measures were the proportion of RCTs that reported each of 22 checklist items of CONSORT. RESULTS: We identified 125 RCTs from 26 journals. Random sequence implementation (0%), estimated effect size and its precision (0%), sample size determination (8.9%), method of random sequence generation (7.3%), allocation concealment (3.2%), participant flow (4.8%) and any other analysis (7.3%), generalizability of the trial findings (0.8%) were pooly reported. CONCLUSION: The proportions of following the CONSORT recommendations in Korean medical journals were very low. An effort to improve the reporting of RCTs by application and recommendation of CONSORT statement is required.
Checklist
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Double-Blind Method
;
Korea
;
Outcome Assessment (Health Care)
;
Random Allocation
;
Sample Size
6.Quality evaluation on Chinese clinical research literatures about dental caries in 1950-2005.
Cai LI ; Yu-qing HAO ; Xue-dong ZHOU
West China Journal of Stomatology 2008;26(1):64-66
OBJECTIVEThe purpose of this study is to evaluate the quality level of Chinese clinical research about dental caries in 1950-2005.
METHODSThe Chinese clinical research literatures about dental caries in 1950-2005 were collected. All the literatures were evaluated by Jadad scale. The score of Jadad scale was form 0 to 5. Score 2 and below was poor quality literature, and score 3 and more was high quality literature. The full marks of Jadad scale was 5.
RESULTS3,201 clinical research papers about dental caries were collected, in which 46 articles were high quality literature. In 3,201 papers, random allocation methods were mentioned in 142 papers, double-blind measure were performed in 26 papers, the withdrawn and missing cases were described in 256 papers.
CONCLUSIONThe high quality literature of Chinese clinical research about dental caries in scientific research design is less. The scientific research design should be strength to enhance the total quality of Chinese clinical research about dental caries.
Dental Caries ; Double-Blind Method ; Humans ; Research Design
7.The Use of Exercise Therapy in Korea as an Adjunct to Nursing Practice.
Journal of Korean Academy of Adult Nursing 1999;11(2):189-204
This study aimed at analyzing the trend of research on the use of exercise therapy in Koera, suggesting directions for future research and implementation of the various exercise therapies. The target population was taken from studies on Exercise Therapy as a nursing interverntion in Domestic Nursing Science, Physiology, Rehabilitation Medicine, and Athletics. Research studies were taken from dissertations and theses selected from Academic Society Journals of nursing science, physiology, rehabilitation medicine and athletics, Journals from universities, medical and nursing schools, and research institutes in various universities, the Central Journal of Medicine, and the New Medical Journal. The studies selected were conducted between 1970 and 1997. The total sample number was 86 different research papers. These studies were analyzed according to Time of Presentation, Theses for a Degree, Experimental Design, Subject, Sample Size, Dependant Variables, Exercise Therapy, and Effect of Exercise Therapy. The results were as follows: 1. The Learning Domain included: 59.3% from Nursing Studies, 22.1% from Athletics research, and 18.6% from the Medical field. 2. Research on exercise therapy has increased rapidly in the 1990's. At the time of this presentation 80.2% of the studies were from the 1990's, and 19.8% were from the 1980's. 3. Thesis areas included : 62.8% non-degree research, 20.9% Doctoral studies, and 16.3% Master's theses. 4. Experimental design parameters includ[ed : 59.3% non-equivalent control group pre-test/post-test design, 30.3% one group pre-test/post-test design, and 10.4% one group post-test only design. 5. Of the Subjects : 54.7% were healthy individuals, and 45.3% were patients with various health problems. 6. Sample size included : 46.5% with above 31 subjects, 15.1% with 11~15 and 12.8% with 6~10. 7. Dependant variables were categorized as : Glucose Metabolism, Lipid Metabolism, Cardio-pulmonary function, Body Composition, Physical Strength, Physical Response, Psychological Response, Activities of Daily Living and the others. Cardio-pulmonary function was measured as a de pendant variable in 91.8%, Body Composition in 89.6%, Lipid Metabolism in 72.1%, Psychological Response in 55.9%, Physical Strength in 47.7%, Physical Response in 46.4%, Glucose Metabolism in 31.4%, Activities of Daily Living in 11.6% and others composed 3.5%. 8. Each Exercise Therapy was analyzed by Type, Intensity, Frequency, Duration, and Period according to each Learning Domain. 1) In the area of Nursing Science : the Type Rhythmic Exercise at 31.4% was the most common, Walking, Jogging, and Running composed 25.5%, Muscle Building Exercise made up 19.6%, and Aquatic Exercise were the least common at 11.8%. Exercise with 40~65% Intensity-comprised 25.5%, Frequency -3~5 X weekly was the most common at 78.4%, while Duration of 15~60 minutes at 76.5%, and Periods-of more than 5 weeks at 82.3% were the most common in their categories. 2) In the area of Medicine : the Type-Walking, Jogging, and Running was the most common at 81.3%, Intensity- of 50~80% was the most common at 31.3%, Frequency of 2~3 X a week was the most common at 31.3% also, while 4~5X a week at 25.0%, and 6 X weekly was the least common at 12.5%. Duration-of 15~60 minutes per session was the most common at 50.0%, while sessions of more than 2 hours were 18.8% and 5~10 minutes sessions were only 12.5%. Periods-of 5 weeks were the most common at 75.0%. 3) In the area of Athletics : the Type Walking, Jogging, and Running at 47.4% was the most common, with Rhythmic Exercise second at 31.6%, and Aquatic Exercise third at 15.8%. Intensity-of 50-80% was the most common at 73.7%. Frequency-of 3~5X a week was the most common at 84.2%. Duration-of 30-60 minutes per session being the commonest choice, while sessions of 6~12 minutes or more than 90 were 15.8%. Exercise periods of more than 8 weeks were the most common at 78.9%, while those of 6 weeks were 15.8%. The exercise methods used to attain Intensity (66.7, 26.3, 62.5%), Frequency(3.9, 15.8, 25.0 %), Duration( 15.8, 21.4, 18.8%) in Nursing Science, Athletics and Medicine were not described in detail. 9. The effect of Exercise Therapy was categorized into 'positive', 'partially positive', 'no effect'according to dependant variables : Having a positive effect Glucose Metabolism and the Others (80.0%), Physical Response (75.7%), Activities of Daily Living(75.0%), Physical Strength (70.7%), Body Composition(67.0%), Psychological Response(62.7%), Cardio pulmonary Function (61.8%). and Lipid Metabolism(55.1%). The following suggestions can be made on the above findings: 1. Research which includes patients with chronic disease needs to be studied. 2. Research findings on Exercise Therapy as a Nursing Intervention need to described by their elements of Type, Intensity, Frequency, Duration and Period. 3. To properly research the positive effects of Exercise Therapy, there needs to be (1) appropriate research design, (2) selection criteria for the subjects of the studies, (3) sample size parameters, and (4) measurement criterion for the dependant variables. 4. Meta-analysis on Exercise Therapy needs to be done to analyze and integrate the various results. 5. The patterns of Exercise Therapy need to be compared with existing international research and current trends for the most effective program design and implementation.
Academies and Institutes
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Activities of Daily Living
;
Body Composition
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Chronic Disease
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Exercise Therapy*
;
Glucose
;
Health Services Needs and Demand
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Humans
;
Jogging
;
Korea*
;
Learning
;
Lipid Metabolism
;
Metabolism
;
Nursing*
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Patient Selection
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Physiology
;
Rehabilitation
;
Research Design
;
Running
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Sample Size
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Schools, Nursing
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Sports
;
Walking
8.Random allocation and dynamic allocation randomization.
Anesthesia and Pain Medicine 2017;12(3):201-212
Random allocation is commonly used in medical researches, and has become an essential part of designing clinical trials. It produces comparable groups with regard to known or unknown prognostic factors, and prevents the selection bias which occurs due to the arbitrary assignment of subjects to groups. It also provides the background for statistical testing. Depending on the change in allocation probability, random allocation is divided into two categories: fixed allocation randomization and dynamic allocation randomization. In this paper, the author briefly introduces both the theory and practice of randomization. The definition, necessity, principal, significance, and classification of randomization are also explained. Advantages and disadvantages of each randomization technique are further discussed. Dynamic allocation randomization (Adaptive randomization), which is as yet unfamiliar with the anesthesiologist, is also introduced. Lastly, the methods and procedures for random sequence generation using Microsoft Excel is provided.
Classification
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Random Allocation*
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Research Design
;
Selection Bias
9.Random allocation and dynamic allocation randomization.
Anesthesia and Pain Medicine 2017;12(3):201-212
Random allocation is commonly used in medical researches, and has become an essential part of designing clinical trials. It produces comparable groups with regard to known or unknown prognostic factors, and prevents the selection bias which occurs due to the arbitrary assignment of subjects to groups. It also provides the background for statistical testing. Depending on the change in allocation probability, random allocation is divided into two categories: fixed allocation randomization and dynamic allocation randomization. In this paper, the author briefly introduces both the theory and practice of randomization. The definition, necessity, principal, significance, and classification of randomization are also explained. Advantages and disadvantages of each randomization technique are further discussed. Dynamic allocation randomization (Adaptive randomization), which is as yet unfamiliar with the anesthesiologist, is also introduced. Lastly, the methods and procedures for random sequence generation using Microsoft Excel is provided.
Classification
;
Random Allocation*
;
Research Design
;
Selection Bias
10.Trends of Occupational Health Nursing Research in Korea.
Korean Journal of Occupational Health Nursing 2011;20(2):195-203
PURPOSE: The purpose of this study was to identify the trends of occupational health nursing research by analyzing the Korean Journal of Occupational Health Nursing for the last 20 years. METHODS: A total of 268 published papers during the 20 year period were analyzed with structured analysis forms. RESULTS: Most of the articles were descriptive, but the number of experimental studies increased. Fifty-five percents of the subjects were healthy workers. Most common selection of subjects appeared to be based on convenience. Sixty-eight percent of research instruments were questionnaires and the reliability and the validity of instruments were described in approximately half of the studies. Parametric statistics were the main methods of data analysis, but some advanced statistics were often used rather than simple descriptive statistics. Mainly "health" has been studied (47.9%) among four meta-paradigms of nursing science. CONCLUSION: It is necessary to develop more rigorous and various research methodology such as longitudinal design, experimental study, or randomized controlled trial. Also, special attention must be paid to studying the environment of workers.
Korea
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Occupational Health
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Occupational Health Nursing
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Patient Selection
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Surveys and Questionnaires
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Research Design
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Statistics as Topic