Background: Urinary bladder sarcomas are rare in adults, accounting for 0.38-0.64% of bladder tumors. The most recognized treatment for malignant tumors is chemotherapy followed by radiotherapy, but there have been no large scale study to provide a definitive regimen for this condition. Objectives: To determine the outcome of patients with urinary bladder sarcomas. Subjects and method: Between January 2002 and December 2006, 6 patients diagnosed with urinary bladder sarcomas were examined at the Viet Duc Hospital. We retrospectively reviewed the records of these patients for information on clinical features, treatment and outcomes. Results: The mean age of patients was 39.6 years; male/female ratio was 3/1; 66% was leiomyosarcomas, 16.7% was rhabdomyosarcomas, 16.7% was myxosarcomas (n=6). Among these malignant tumors, 3/5 patients were in the advanced stage. Conclusion: Bladder sarcomas were rare in adults. Leiomyosarcomas were more common than rhabdomyosarcomas and had worst outcomes if it is in an advanced stage.
Bladder sarcoma ; Surgery

Biomarkers, Tumor ; Humans ; Sarcoma, Synovial/surgery* ; Stomach

Humans ; Sarcoma, Synovial ; Larynx ; Laryngeal Neoplasms/surgery*

Humans ; Fibrosarcoma/surgery* ; Sarcoma ; Temporal Bone ; Soft Tissue Neoplasms/surgery*

Primary cardiac sarcoma is a rare disease in adults. It is also associated with poor prognoses, due to diagnostic delay, therapeutic difficulty, and high metastatic potential. The coincidence of pregnancy and a primary cardiac intimal sarcoma is extremely rare. We report a pregnant woman at 27(+5) weeks gestation who was admitted to the hospital with acute-onset dyspnea. A mass was found on the left atrium by transthoracic echocardiography. Subsequently, the intracardiac mass was removed, and mitral valve replacement and modified DeVega tricuspid annuloplasty were performed. The patient was diagnosed with a undifferentiated sarcoma, and gave birth to a 1,230 g living baby boy by Caesarean section from preterm contraction at 29(+5) weeks gestation. The patient then received systemic chemotherapy. However, 10 months after the initial clinical onset, the patient suddenly died. Surgery is the standard treatment for cardiac tumors, and their removal should always be attempted, even in pregnant women. Although the overall survival rates of the patients are rather poor, palliative cardiac surgery allows the prolonging of pregnancy, until an acceptable fetal viability level is reached.
Sarcoma/*surgery ; Pregnancy Complications, Neoplastic/*surgery ; Pregnancy ; Humans ; Heart Neoplasms/*surgery ; Female ; Cardiopulmonary Bypass ; Adult

OBJECTIVETo investigate the clinical characteristics, diagnosis, treatment and prognosis of deep sarcoma of the penis.

METHODSThe pathological and clinical data of 2 cases of deep sarcoma of the penis were analyzed retrospectively and the literature reviewed.

RESULTSBoth of the cases were treated by total penectomy. Epithelioid angiosarcoma of the penis was confirmed by postoperative pathology in one patient, who died of pulmonary metastasis in the eighth month after the operation; and epithelioid sarcoma of the penis was confirmed in the other, who died of brain metastasis in the second month after the operation.

CONCLUSIONDeep sarcoma of the penis is rare but can be diagnosed pathologically. Total penectomy is the main option for its treatment. Node dissection, with poor prognosis, is not recommended unless adenopathy is palpable.

Fatal Outcome ; Humans ; Male ; Middle Aged ; Penile Neoplasms ; diagnosis ; surgery ; Prognosis ; Retrospective Studies ; Sarcoma ; diagnosis ; surgery

OBJECTIVETo enhance the knowledge and the effect of the diagnosis and treatment of primary epithelioid sarcoma of the penis.

METHODSOne rare case of primary epithelioid sarcoma of the penis was studied with regard to its primary clinical process and characteristics, differential diagnosis and method of treatment.

RESULTSAn operation was performed on the penis to treat the epithelioid sarcoma. The diagnosis was confirmed by immunohistological and pathological techniques. There was no evidence of relapse during the three-year follow-up after operation.

CONCLUSIONThe possibility of primary epithelioid sarcoma of the penis should be considered if a mass or induration of the proximal penis and the symptoms of urethremphraxis are found. Total phallectomy could be chosen as an appropriate method of treatment. Unless adenopathy is palpable, node dissections are not recommended.

Adult ; Diagnosis, Differential ; Humans ; Male ; Penile Neoplasms ; diagnosis ; pathology ; surgery ; Sarcoma ; diagnosis ; pathology ; surgery

BACKGROUNDPulmonary artery sarcoma originating from the pulmonary artery is a rare disease and its prognosis is extremely poor. Most patients are initially thought to have pulmonary embolism.

METHODSFive patients (3 males and 2 females, mean age was (42.0 ± 8.5) years) of primary pulmonary artery sarcomas underwent surgical procedures. Sarcoma resection and right ventricle outflow tract reconstruction were performed.

RESULTSThere was no death 30 days post-operation except one patient. The function of heart was improved to NYHA II.

CONCLUSIONSGiven the significant morbidity and mortality of pulmonary artery sarcomas, an aggressive strategy for resection is indicated. Early diagnosis and complete surgical resection is perhaps the best way to improve patients' survival with pulmonary artery sarcoma.

Adult ; Female ; Humans ; Male ; Middle Aged ; Pulmonary Artery ; pathology ; surgery ; Sarcoma ; surgery ; Treatment Outcome

OBJECTIVETo investigate the clinical characteristics of primary adult renal sarcoma.

METHODSA total of 1654 cases with adult renal tumors were treated during 1985 to 2009 in Peking Union Medical College Hospital. Of all, 17 cases were diagnosed as primary renal sarcoma and underwent radical nephrectomy. The clinical features of 17 such patients were retrospectively analyzed.

RESULTSThe first symptom of 10 (59%) cases in all renal sarcomas was abdominal mass. The pathological diagnosis was leiomyosarcoma (7 cases), rhabdomyosarcoma (2 cases), malignant fibrous histiocytoma (2 cases), low-differentiated sarcoma (2 cases), chromophobe renal cell carcinoma coexisting with liposarcoma (1 case), fibrosarcoma (1 case), embryonic sarcoma (1 case) and leiomyosarcoma (1 case). One patient died of tumor thrombus of the inferior vena cava during surgery. Finally, 15 cases were regularly followed up for 4 to 60 months. Till now, 1 had tumor-free survival for 9 months, and the other 14 cases died 2-38 months after the operation with a median survival time of 18 (range, 5-60) months. The median survival time of leiomyosarcoma group was 28 (range, 11-60) months, and 2 cases of malignant fibrous histiocytoma died 4 and 8 months after the operation respectively.

CONCLUSIONSThe primary renal sarcoma has the clinical symptom similar with advanced renal cell carcinoma and has poor prognosis. Leiomyosarcoma might have relative good prognosis.

Adult ; Aged ; Female ; Humans ; Kidney Neoplasms ; diagnosis ; surgery ; Male ; Middle Aged ; Sarcoma ; diagnosis ; surgery

Child, Preschool ; Female ; Humans ; Sarcoma ; diagnosis ; surgery ; Stomach Neoplasms ; diagnosis ; surgery ; Stromal Cells ; pathology