Background: Sarcoidosis is a rare systemic granulomatous disorder with unknown cause. It is rare in the world and Vietnam. Objective: To study clinical, subclinical manifestations and therapy of sarcoidosis in Department of Respiratory of Bach Mai Hospital. Subjects and method: A study included 14 patients in Department of Respiratory of Bach Mai hospital, from 1989 to August 2006. This was a retrospective, descriptive study. Results and conclusions: In 14 patients, 14 patients (78.6%) was females, 3 (21.4%) was males. The disease occurred common in the ages of 20-49 years (85.7%). The clinical symptoms were very multiform but pulmonary symptoms were the most manifestations (78.6%). Abnormalities on chest radiographs were 92.8%, with stage 0 (7.1%), stage 1 (57.2%), stage 2 (28.6%), stage 3 (7.1%). Histopathologically, injuries of the sarcoidosis were typical in 9 patients (64.3%). The corticoid therapy satisfied the most success in 92.8% of patients. The side effects of the treatment occurred in 4 of 12 patients.
Sarcoidosis/ diagnosis ; therapy

Although acquired ichthyosis has been associated with a number of systemic illnesses, an association with sarcoidosis has rarely been reported. We report a patient with aquired ichthyosis of the lower and upper extrimities whose diagnosis of cutaneous sarcoidosis was confirmed by histologic examination. Systemic involvement in the patient revealed occular, pulmonary and nerve disease. A diagnosis of sarcoidosis must be considered when a patient presents with acquired ichthyosis.
Diagnosis ; Humans ; Ichthyosis ; Sarcoidosis*

Adult ; Humans ; Male ; Pneumothorax ; pathology ; Sarcoidosis ; diagnosis

Diagnosis ; Humans ; Malaysia ; Neoplasms ; epidemiology ; Pathology ; Sarcoidosis

We report a case of sarcoidosis in a 4-year-old girl. She showed the involvements of the skin and eye, which are the characteristics of sarcoidosis in very young patients, and also showed an unusual finding of hepatosplenomegaly. Because the diagnosis of childhood sarcoidosis is difficult and serious sequelae can develop from sarcoidal uveitis, an early skin biopsy and regular ophthalmologic assessment are essential.
Biopsy ; Child, Preschool ; Diagnosis ; Female* ; Humans ; Sarcoidosis* ; Skin ; Uveitis

Scar sarcoidosis is a cutaneous manifestation of sarcoidosis arising on old cutaneous scars. We report four cases of scar sarcoidosis after blepharoplasty. Lesions were seen to manifest as erythematous, firm, and non-tender nodules diffusely palpable along an upper eyelid scar. Histologically, numerous non-caseating granulomas with multinucleated giant cells were seen. No other evidence of systemic sarcoidosis was observed in any patient. Although rare, sarcoidosis may occur in an eyelid scar after a blepharoplasty. Therefore, scar sarcoidosis should be considered in the differential diagnosis in patients presenting with unusual nodules in blepharoplasty scars.
Blepharoplasty* ; Cicatrix* ; Diagnosis, Differential ; Eyelids ; Giant Cells ; Granuloma ; Humans ; Sarcoidosis*

We present herein a 36-year-old female patient with cutaneous sarcoidosis resulting from scars produced by blepharoplasty and trauma in the past. The patient showed multiple nodules in the scar areas simultaneously and there was no evidence of systemic involvement. Diagnosis of sarcoidosis was confirmed by histological findings of biopsy and Kveim test.
Adult ; Biopsy ; Blepharoplasty ; Cicatrix* ; Diagnosis ; Female ; Humans ; Kveim Test ; Sarcoidosis

Pseudotumor is a term used to describe a space occupying inflammatory lesion which mimics a true neoplastic process in its clinical presentation and radiologic findings. Its occurrence in the maxillary sinus is rare. The etiology and pathophysiology of the maxillary pseudotumor is unknown. A large and longstanding pseudotumor may induce the erosion or destruction of the maxillary bone wall. Therefore it may be difficult to distinguish such a lesion from a malignant tumor, specific granulomatous disease (e.g. tuberculosis, sarcoidosis, Wegener's granulomatosis) and fungal sinusitis preoperatively. A diagnosis of maxillary pseudotumor must be based on histological evidence to exclude other disease. We report a case of a 49-year-old patient with left maxillary pseudotumor that simulated an aggressive neoplasm in its clinical presentation and radiologic findings.
Diagnosis ; Humans ; Maxilla ; Maxillary Sinus* ; Middle Aged ; Sarcoidosis ; Sinusitis ; Tuberculosis

Sarcoidosis is a multisystem granulomatous disorder of unknown etiology presenting with bilateral hilar lymphadenopathy, pulmonary, skin, and eye lesion. Sarcoidosis involving skeletal muscle is rare and occurs in two forms, nodular and myopathic. In the nodular variety, patients have single or multiple nodules in the skeletal muscles. Patients with the myopathic type have myalgia, muscle weakness, and atrophy. To our knowledge, this is the first case of sarcoidosis involving skeletal muscle in Korea. In this report, we describe a 40-year-old man presenting with nodular type of muscular sarcoidosis and stage II pulmonary sarcoidosis. By this case, we emphasize the usefulness of magnetic resonance imaging in the diagnosis of nodular type of muscular sarcoidosis.
Adult ; Atrophy ; Diagnosis ; Humans ; Korea ; Lymphatic Diseases ; Magnetic Resonance Imaging ; Muscle Weakness ; Muscle, Skeletal* ; Myalgia ; Sarcoidosis* ; Sarcoidosis, Pulmonary ; Skin

Gastric sarcoidosis is a rare disease accounting for 0.1~0.9% of all sarcoidosis cases. It presents either as a systemic disease or as an isolated finding. Diagnosis is established with biopsy of a lesion. It is important to distinguish between sarcoidosis and a sarcoid-like reaction, which can be caused by Crohn's disease, foreign body reaction, fungal infection, tuberculosis, or malignancy. We report a 60-year-old woman with both gastric and pulmonary sarcoidosis.
Biopsy ; Crohn Disease ; Diagnosis ; Female ; Foreign-Body Reaction ; Humans ; Middle Aged ; Rare Diseases ; Sarcoidosis ; Sarcoidosis, Pulmonary* ; Stomach ; Tuberculosis