1.Clinical evaluation of efficiency and complications in ESWL therapy of urolithiasis
Chongbiao DING ; Baikang CHEN ; Hongyuan YU ; Tianji WANG ; Sanhua CHEN ; Feiping LI ; Songjiang WU ; Ziwen LU ; Mang KE
Journal of Clinical Urology 2001;16(4):150-152
Purpose:To further improve the therapeutic results of ESWL and to reduce the complications of ESWL. Methods: Clinical materials of 5 140 cases of patients with urinary calculi underwent ESWL from 1989 to 1999 were analyzed retrospectively. Results: Ignorance of the routine examination in urine, blood, hepatic func tion and specialization etc, the serious complications may be produced by ESWL. Low energy and emergency ESWL have obtained satisfactory results. Conclusions:Every routine examination is essential to secure the patient to get satisfactory therapeutic result from ESWL and prevent the complication from occurring. Complete dis charge rate of stones was affected by the tissue structure and type of the renal pelvis and calyces, beside the site of stones.
2.Clinical significance of detection of mtMSI and Hp in the diagnosis of esophageal squamous cell carcinoma
Qianqian PENG ; Sanhua DENG ; Peisheng CHEN ; Fengjian HE ; Shenghao XU
Journal of International Oncology 2017;44(10):727-730
Objective To detect the mitochondrial microsatellite instability (mtMSI) and Helicobacter pylori (Hp) infection status in esophageal squamous cell carcinoma (ESCC),and to analyze their clinical significance in the diagnosis of ESCC.Methods The mtMSI and Hp infection status were examined by immunohistochemical SP method in 93 cases of ESCC and their normal control tissues.The relationship between Hp and mtMSI and their correlations with the clinicopathological features of ESCC were analyzed.Results The Hp positive rates of ESCC group and control group were 61.3% (57/93) and 20.4% (19/93) respectively,and there was statistically significant difference between the two groups (x2 =32.127,P <0.001).The mtMSI positive rates of ESCC group and control group were 34.4% (32/93) and 0 (0/93) respectively,and there was statistically significant difference between the two groups (x2 =38.649,P <0.001).The Hp infection was correlated with tumor infiltrating degree (x2 =22.213,P < 0.001) and lymph node metastasis (x2 =8.318,P =0.004),but was not correlated with gender (x2 =0.330,P =0.565),major axis of tumor (x2 =0.692,P =0.406),gross type (x2 =1.006,P =0.316),differentiated degree (x2 =0.665,P =0.415).The mtMSI was not correlated with gender (x2 =0.163,P =0.686),major axis of tumor (x2 =0.384,P =0.530),gross type (x2 =0.422,P =0.516),differentiated degree (x2 =0.213,P =0.645),infiltrating degree (x2 =0.001,P =0.979) or lymph node metastasis (x2 =0.039,P =0.843).The Hp infection was positively associated with mtMSI in ESCC (r =0.864,P =0.006).Conclusion The positive rates of Hp and mtMSI in ESCC are higher than those in normal tissues,and there is a close relationship between Hp and mtMSI.Hp is also associated with the progression of ESCC.