1.Cross-Sectional and Skeletal Anatomy of Long-tailed Gorals (Naemorhedus caudatus) Using Imaging Evaluations
Sangjin AHN ; Woojin SHIN ; Yujin HAN ; Sohwon BAE ; Cheaun CHO ; Sooyoung CHOI ; Jong-Taek KIM
Journal of Veterinary Science 2023;24(4):e60-
Background:
Accurate diagnosis of diseases in animals is crucial for their treatment, and imaging evaluations such as radiographs, computed tomography (CT), and magnetic resonance imaging (MRI) are important tools for this purpose. However, a cross-sectional anatomical atlas of normal skeletal and internal organs of long-tailed gorals (Naemorhedus caudatus) has not yet been prepared for diagnosing their diseases.
Objectives:
The objective of this study was to create an anatomical atlas of gorals using CT and MRI, which are imaging techniques that have not been extensively studied in this type of wild animal in Korea.
Methods:
The researchers used CT and MRI to create an anatomical atlas of gorals, and selected 37 cross-sections from the head, thoracic, lumbar, and sacrum parts of gorals to produce an average cross-sectional anatomy atlas.
Results:
This study successfully created an anatomical atlas of gorals using CT and MRI.
Conclusions
The atlas provides valuable information for the diagnosis of diseases in gorals, which can improve their treatment and welfare. The study highlights the importance of developing cross-sectional anatomical atlases of gorals to diagnose and treat their diseases effectively.
2.How Many SNPs Should Be Used for the Human Phylogeny of Highly Related Ethnicities? A Case of Pan Asian 63 Ethnicities.
Hoyoung GHANG ; Youngjoo HAN ; Sangjin JEONG ; Jong BHAK ; Sunghoon LEE ; Tae Hyung KIM ; Chulhong KIM ; Sangsoo KIM ; Fahd AL-MULLA ; Chan Hyun YOUN ; Hyang Sook YOO
Genomics & Informatics 2011;9(4):181-188
In planning a model-based phylogenic study for highly related ethnic data, the SNP marker number is an important factor to determine for relationship inferences. Genotype frequency data, utilizing a sub sampling method, from 63 Pan Asian ethnic groups was used for determining the minimum SNP number required to establish such relationships. Bootstrap random sub-samplings were done from 5.6K PASNPi SNP data. DA distance was calculated and neighbour-joining trees were drawn with every re-sampling data set. Consensus trees were made with the same 100 sub-samples and bootstrap proportions were calculated. The tree consistency to the one obtained from the whole marker set, improved with increasing marker numbers. The bootstrap proportions became reliable when more than 7,000 SNPs were used at a time. Within highly related ethnic groups, the minimum SNPs number for a robust neighbor-joining tree inference was about 7,000 for a 95% bootstrap support.
Asian Continental Ancestry Group
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Consensus
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Ethnic Groups
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Genotype
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Humans
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Phylogeny
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Polymorphism, Single Nucleotide
3.A Case of Splenic Botryomycosis Caused by Streptococcus mitis in a Patient with a Previous Distal Gastrectomy.
Yang Hee HAN ; Sang Jin LEE ; Jun Sung KWON ; Kyoo Ho CHOI ; Moon Ho KIM ; Eun Hee SONG ; Gil Hyun KANG
Korean Journal of Medicine 2015;88(5):608-611
Botryomycosis is an uncommon chronic suppurative bacterial infection of the skin and visceral organs seen primarily in immunocompromised patients. Here, we report a case of splenic botryomycosis caused by Streptococcus mitis in a 53-year-old immunocompetent woman with a history of distal gastrectomy for advanced gastric cancer.
Bacterial Infections
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Female
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Gastrectomy*
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Humans
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Immunocompromised Host
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Middle Aged
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Skin
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Spleen
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Stomach Neoplasms
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Streptococcus mitis*
4.A 4-Week, Two-Center, Open-Label, Single-Arm Study to Evaluate the Safety and Efficacy of EOPatch in Well-Controlled Type 1 Diabetes Mellitus
Jiyun PARK ; Nammi PARK ; Sangjin HAN ; You-Bin LEE ; Gyuri KIM ; Sang-Man JIN ; Woo Je LEE ; Jae Hyeon KIM
Diabetes & Metabolism Journal 2022;46(6):941-947
This study evaluated the safety and efficacy of tubeless patch pump called EOPatch in patients with well-controlled type 1 diabetes mellitus (T1DM). This 4-week, two-center, open-label, single-arm study enrolled 10 adult patients diagnosed with T1DM with glycosylated hemoglobin less than 7.5%. The co-primary end points were patch pump usage time for one attachment and number of serious adverse events related to the patch pump. The secondary end points were total amount of insulin injected per patch and changes in glycemic parameters including continuous glucose monitoring data compared to those at study entry. The median usage time per patch was 84.00 hours (interquartile range, 64.50 to 92.50). Serious adverse events did not occur during the trial. Four weeks later, time in range 70 to 180 mg/dL was significantly improved (70.71%±17.14 % vs. 82.96%±9.14%, P=0.01). The times spent below range (<54 mg/dL) and above range (>180 mg/dL) also improved (All P<0.05). Four-week treatment with a tubeless patch pump was safe and led to clinical improvement in glycemic control.
5.Mucosal Incision and Forceps Biopsy for Reliable Tissue Sampling of Gastric Subepithelial Tumors.
Sa Young SHIN ; Sang Jin LEE ; Jae Hyuck JUN ; Jong Kyu PARK ; Hyun Il SEO ; Koon Hee HAN ; Young Don KIM ; Woo Jin JEONG ; Gab Jin CHEON
Clinical Endoscopy 2017;50(1):64-68
BACKGROUND/AIMS: The diagnostic efficacy of current tissue sampling techniques for gastric subepithelial tumors (SETs) is limited. Better tissue sampling techniques are needed to improve pathological diagnosis. The aim of this study was to evaluate the safety and efficacy of a new technique, mucosal incision and forceps biopsy, for reliable tissue sampling of gastric SETs. METHODS: This study enrolled 12 consecutive patients who underwent mucosal incision and forceps biopsy of gastric SETs between November 2011 and September 2014 at Gangneung Asan Hospital. The medical records of patients were reviewed retrospectively. The safety and diagnostic yield of this method were evaluated. RESULTS: By performing mucosal incision and forceps biopsy, we were able to provide a definitive histological diagnosis for 11 out of 12 cases. The pathological diagnoses were leiomyoma (3/11), gastrointestinal stromal tumor (GIST; 2/11), lipoma (2/11), schwannoma (1/11), and ectopic pancreas (3/11). In cases of leiomyoma (n=3) and GIST (n=2), tissue samples were of sufficient size to allow immunohistochemical staining. In addition, the mitotic index was evaluated in two cases of GIST. There were no procedure-related complications. CONCLUSIONS: Mucosal incision and forceps biopsy can be used as one of several methods to obtain adequate tissue samples from gastric SETs.
Biopsy*
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Chungcheongnam-do
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Diagnosis
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Gangwon-do
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Gastrointestinal Stromal Tumors
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Gastroscopy
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Humans
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Leiomyoma
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Lipoma
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Medical Records
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Methods
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Mitotic Index
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Neurilemmoma
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Pancreas
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Retrospective Studies
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Stomach
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Surgical Instruments*