1.First Nationwide Mpox Vaccination Program in the Republic of Korea:Implications for an Enhanced Public Health Response
Seunghyun Lewis KWON ; Minju SONG ; Wonkyung LEE ; Jeeyeon SHIN ; Su-Yeon LEE ; Sang-Gu YEO ; Minjeong KIM ; Sanggyun JEONG ; Joonku PARK ; Dongwoo LEE ; Sookyoung LIM
Journal of Korean Medical Science 2024;39(32):e235-
On May 1, 2024, the Republic of Korea lifted the infectious disease crisis alert for mpox, almost two years after the first case was reported. The Korea Disease Control and Prevention Agency (KDCA) has led the response, which included diagnosis, epidemiological investigations, treatment, and vaccination. This article particularly reviews the vaccination strategy implemented and proposes suggestions for enhancing future response efforts. Initially, the KDCA recommended pre-exposure prophylaxis for high-risk groups, later expanding to include broader demographics as domestic cases rose. By April 2024, a total of 6,863 individuals had received their first vaccine dose, with 3,875 completing the second dose of third-generation vaccines. Strategies to improve future responses include addressing stigma, securing nationally representative safety data, and conducting vaccine cost-benefit analyses.These measures will help ensure a robust and effective response to future outbreaks.
2.First Nationwide Mpox Vaccination Program in the Republic of Korea:Implications for an Enhanced Public Health Response
Seunghyun Lewis KWON ; Minju SONG ; Wonkyung LEE ; Jeeyeon SHIN ; Su-Yeon LEE ; Sang-Gu YEO ; Minjeong KIM ; Sanggyun JEONG ; Joonku PARK ; Dongwoo LEE ; Sookyoung LIM
Journal of Korean Medical Science 2024;39(32):e235-
On May 1, 2024, the Republic of Korea lifted the infectious disease crisis alert for mpox, almost two years after the first case was reported. The Korea Disease Control and Prevention Agency (KDCA) has led the response, which included diagnosis, epidemiological investigations, treatment, and vaccination. This article particularly reviews the vaccination strategy implemented and proposes suggestions for enhancing future response efforts. Initially, the KDCA recommended pre-exposure prophylaxis for high-risk groups, later expanding to include broader demographics as domestic cases rose. By April 2024, a total of 6,863 individuals had received their first vaccine dose, with 3,875 completing the second dose of third-generation vaccines. Strategies to improve future responses include addressing stigma, securing nationally representative safety data, and conducting vaccine cost-benefit analyses.These measures will help ensure a robust and effective response to future outbreaks.
3.First Nationwide Mpox Vaccination Program in the Republic of Korea:Implications for an Enhanced Public Health Response
Seunghyun Lewis KWON ; Minju SONG ; Wonkyung LEE ; Jeeyeon SHIN ; Su-Yeon LEE ; Sang-Gu YEO ; Minjeong KIM ; Sanggyun JEONG ; Joonku PARK ; Dongwoo LEE ; Sookyoung LIM
Journal of Korean Medical Science 2024;39(32):e235-
On May 1, 2024, the Republic of Korea lifted the infectious disease crisis alert for mpox, almost two years after the first case was reported. The Korea Disease Control and Prevention Agency (KDCA) has led the response, which included diagnosis, epidemiological investigations, treatment, and vaccination. This article particularly reviews the vaccination strategy implemented and proposes suggestions for enhancing future response efforts. Initially, the KDCA recommended pre-exposure prophylaxis for high-risk groups, later expanding to include broader demographics as domestic cases rose. By April 2024, a total of 6,863 individuals had received their first vaccine dose, with 3,875 completing the second dose of third-generation vaccines. Strategies to improve future responses include addressing stigma, securing nationally representative safety data, and conducting vaccine cost-benefit analyses.These measures will help ensure a robust and effective response to future outbreaks.
4.First Nationwide Mpox Vaccination Program in the Republic of Korea:Implications for an Enhanced Public Health Response
Seunghyun Lewis KWON ; Minju SONG ; Wonkyung LEE ; Jeeyeon SHIN ; Su-Yeon LEE ; Sang-Gu YEO ; Minjeong KIM ; Sanggyun JEONG ; Joonku PARK ; Dongwoo LEE ; Sookyoung LIM
Journal of Korean Medical Science 2024;39(32):e235-
On May 1, 2024, the Republic of Korea lifted the infectious disease crisis alert for mpox, almost two years after the first case was reported. The Korea Disease Control and Prevention Agency (KDCA) has led the response, which included diagnosis, epidemiological investigations, treatment, and vaccination. This article particularly reviews the vaccination strategy implemented and proposes suggestions for enhancing future response efforts. Initially, the KDCA recommended pre-exposure prophylaxis for high-risk groups, later expanding to include broader demographics as domestic cases rose. By April 2024, a total of 6,863 individuals had received their first vaccine dose, with 3,875 completing the second dose of third-generation vaccines. Strategies to improve future responses include addressing stigma, securing nationally representative safety data, and conducting vaccine cost-benefit analyses.These measures will help ensure a robust and effective response to future outbreaks.
5.Modified Charlson comorbidity index as a survival prediction tool for older patients after liver transplantation
Jiho CHOI ; Eun-Woo CHOI ; YoungRok CHOI ; Su young HONG ; Sanggyun SUH ; Kwangpyo HONG ; Eui Soo HAN ; Jeong-moo LEE ; Suk Kyun HONG ; Nam-Joon YI ; Kwang-Woong LEE ; Kyung-Suk SUH
Annals of Surgical Treatment and Research 2023;104(6):358-363
Purpose:
An increasing number of older patients now undergo liver transplantation (LT). Although the overall outcomes in older patients are not different from those of younger patients, there is no tool to predict LT prognosis in older patients.We hypothesized that a modified Charlson comorbidity index (mCCI) and 5-factor modified frailty index (mFI-5) can predict outcomes in older patients after LT.
Methods:
This retrospective study included 155 patients (aged >65 years) who underwent LT at Seoul National University Hospital. The recipients were subcategorized into 2 groups based on the mCCI score and mFI-5: the low (0–1) and high (2–5) mCCI groups, and low (≤0.4) and high (>0.4) mFI-5 groups. The independent effect of each variable on post-LT survival was determined using the mCCI subgroup, age at transplantation, sex, Child-Turcotte-Pugh score, model for end-stage liver disease (MELD) score, and mFI-5 subgroup.
Results:
The high-mCCI group (41 patients) showed significantly lower 1- and 3-month and 1-, 3-, and 5-year survival than the low-mCCI group. Using the Cox regression model, the mCCI, sex, and MELD score remained significant. The mFI-5 was not a significant factor to predict patients’ survival.
Conclusion
The mCCI and MELD scores could be used to predict post-LT survival in older patients.