No abstract available.
DNA*

Acute hematogenous osteomyelitis adjacent to hip, though uncommon, should be included in the differential diagnosis of the patients presenting symptoms suggestive of septic arthritis of hip. When it occurs in children, it is particularly serious, because the diagnosis at first may be very difficult to be made. Our observations on seven cases reported here suggest the following findings to be helpful for early differential diagnosis of osteomyelitis of innominate bones from septic hip. 1. Among 7 cases, 4 had lesions in ischium, and 3 in os ilii. 2. The initial diagnosis on admission in 3 cases out of 7 was wrongly made to be septic arthritis of hip. 3. Early accurate diagnosis is essential to initiate early treatment, and there by shortens the convalescent time and minimize sequelae. 4. The diagnosis could be made in the cases by clinical and roentgenographic findings, such as fever, pain nature, antalgic posture of hip together with range of hip motion, tender point around hip and positive soft tissue and bony X-ray findings, but K-ray taken on early stage of infection could not provide any clue until bone lesion appears. 5. Gentle passive motion of hip is more easily permitted without eliciting severe pain and restriction of motion in the infection of innominate bone than in the septic hip. This also can be another clue to differentiate the acute osteomyelitis of innominate bone from septic arthritis of the hip.
Arthritis, Infectious ; Child ; Diagnosis ; Diagnosis, Differential ; Fever ; Hip ; Humans ; Ischium ; Osteomyelitis ; Pelvic Bones ; Posture

An immunohistochemical study on the tissue localization of human chorionic gonadotropin (HCG), human placental lactogen (HPL), and human pregnancy specific bata-1 glycoprotein (SP-1) in the non-neoplastic (5 incomplete abortion, 5 ectopic pregnancy) and neoplastic (hydatidiform mole 3 cases, 5 ectopic pregnancy) and neoplastic (hydatidiform mole 3 cases, choriocarcinoma 2 cases) gestational status, and germ cell tumors of the ovary (dysgerminoma 2 cases, immature teratoma 1 case) and the testis (seminoma 2 cases, endodermal sinus tumor 1 case) by means of sensitive peroxidase-antiperoxidase method. The results were as follows. 1) Cytoplasmic HCG, HPL, and SP-1 were readily identified in syncytiotrophoblasts of chorionic villi of the incomplete abortion and ectopic pregnancy, as moderate to strong positive reactions. In the cytoplasm of the neoplastic syncytiotrophblasts of hydatidiform mole and choriocarcinoma, positive reactions were stronger than in non-neoplastic syncytiotrophblasts. but the cytotrophoblasts and villous stromal cells showed negative reactions to these hormones. 2) All of the tumor cells of dysgerminoma and immature teratoma of the ovary, and seminoma and endodermal sinus tumor of the testis showed negative reactions to HCG, HPL, and SP-1. According to these results, HCG, HPL, and SP-1 are specifically synthesized and secreted by normal or neoplastic syncytiotrophoblasts Malignant tumors originated from other cells or tissues than trophoblastic cells show elevated serum concentration of these hormones are only evident in the presence of syncytiotrophoblastic giant cells among the tumor cells.
Pregnancy ; Female ; Humans

No abstract available.
Knee Joint* ; Knee*

No abstract available.

BACKGROUND: Platelet activation has been implicated in the pathogenesis of a number of diseases, which include atherosclerosis, coronary vascular disease, and cerebrovascular disease. There have been controversies with the influence of hormone therapy on platelet activation. The purpose of this study was to define the effect of long-term hormone therapy on platelet activation. METHODS: We recruited a total of 162 postmenopausal women aged 55 and above among wihch eighty healthy postmenopausal women had received hormone therapy for more than 5 years and the remaining eighty- two healthy postmenopausal women with no hormone therapyapy. Baseline characteristics as well as the parameters related to platelet activation were compared between the two groups using T-test. After platelet activation was defined by the reference range, multivariated logistic regression analysis was performed determining the odds ratio of hormone therapy on platelet activation. RESULTS: The MPC and PCDW were significantly lower in the HT group than the Non-HT group (P<0.001), which suggests that platelets were more activated in the HT group more than in the non-HT group. Multiple logistic regression analysis showed that the odds ratio of the possibility of platelet activation in HT group was 19 times (P<0.001). CONCLUSION: Long term hormone therapy increased platelet activation significantly, which may be a contributing factor of thromboembolism.
Coronary Artery Disease ; Estrogens ; Female ; Humans ; Logistic Models ; Menopause ; Odds Ratio ; Platelet Activation* ; Reference Values ; Thromboembolism ; Vascular Diseases

For the morphological analysis of DMBA (9,10-diemethyl-1,2-benzanthracene) induced tumor, thirty Sprague-Dawley rats were received 0.1 ml of a 2% paraffin solution of DMBA into the knee joint cavity, which was repeated three times at an interval of 4 weeks. The induced tumor masses were removed at the 12th week after the first injection. Histological and histochemical examinations (H & E, PAS, alcian blue, Van Gieson, prussian blue, reticulin, PTAH stain) and enzyme histochemical examinations (acid phosphatase, alkaline phosphatase, alpha-naphthyl acetate esterase) were performed. The results were as follows: 1) By the 12th week after the first injection of DMBA, the tumor incidence rate was 20 percent. 2) On histological and histochemical examination, most of the induced tumor disclosed the features of the fibrous histiocytoma originating from mesenchymal cells, and the remains sweat gland adenoma and adenocarcinoma originating from epithelial cells. 3) On enzyme histochemical examination, most of the mesenchymal cell-derived tumor cells showed positive reactions for acid phosphatase and alpha-naphthyl acetate esterase, which were similar characteristic features of enzyme stains as shown in the component cells of fibrous histiocytoma.
Rats ; Animals ; Incidence ; Adenocarcinoma ; Adenoma

No abstract available.
Nephrotic Syndrome*

No abstract available.
Hepatitis*

BACKGROUND: Social support is defined as interpersonal transaction ; the giving of symbolic or material aid to another. It has been shown to have both buffering effects and direct beneficial effects on diverse health related outcomes. But there has been the dearth of well-validated measurement instruments. This article describes the development of Korean version of the Duke-UNC functional social support questionnaire(DUFSS), focusing on the aspect of social support. METHODS: The 13-item, self-administered questionnaire was translated to Korean language. It was evaluated on 177 patients attending the family medicine clinic of Seoul National University Hospital during one month(November, 1996.) Comparisons to the family APGAR, COOP/ WONCA functional status chart are made to assess validity. Factor analyses are performed. Correlation of the questionnire score with the sum of family APGAR and each items of COOP/ WONCA functional chart are measured Internal consistency are evaluated. RESULTS: The questionnaire score are correlated with significantly correlated with social activity item. The total Cronbachs alpha is calculated as 0.89. The four content areas developed by factor analyses are donfidant support(items 8, 9, 10), af fective support(items 4, 5, 6, 7), instrumental support(items 3, 12) and quantity of support(item 1). These shows similarity to American study results. CONCLUSIONS: The Korean version of the Duke-UNC functional social support questionnaire has been documented as having high reliability and moderate validity. It covers two dimensions well(confidant support, affective support) with a small enough number of questions. Instrumental support may need further study.
Humans ; Seoul ; Surveys and Questionnaires