2.Laserthermia Induced Histological Changes in Different Thermal Condition.
Sang Woo KIM ; Kyung Yup LEE ; Seong Ho KIM ; Jang Ho BAE ; Oh Lyong KIM ; Byung Yearn CHOI ; Soo Ho CHO
Yeungnam University Journal of Medicine 1995;12(2):331-338
Laserthermia is a new method of local hyperthermia using fiber optic guided probe with computer controlled Nd-YAG laser system. We used a synthetic sapphire probe and allowed irradiation with contolled low power laser energy (less than 5W), in different thermal condition (temprature:38.5-50 degrees C) for 10 minutes, in the normal brain tissue of 18 rabbits. In results, the histological changes of brain tissue was variable (myelin condensation, chromatin condensation, nuclear waving and palisading, RBC discoloration, cell necrosis) in microscopic findings after laser irradiation, but changing area was not occured proportionally in thermal condition level. Cell necrosis appears to over 44.5 degrees C and the distance was about 1.25 mm. This study, using computer controlled laserthermia system for interstitial local hyperthermia, may offer many advantages in the experimental treatment and clinical management of tumor. Minimizing normal tissue damage is now being developed.
Aluminum Oxide
;
Brain
;
Chromatin
;
Hyperthermia, Induced
;
Lasers, Solid-State
;
Necrosis
;
Rabbits
3.A Case of Congenital Omental Cyst.
Sung Uk CHOI ; Sang Yup OH ; Joon Cheol PARK ; Jeong Ho RHEE ; Jong In KIM
Korean Journal of Perinatology 2002;13(3):284-288
Omental cyst is a rare disease and its accurate time and cause of outbreak has not been reported. This disease is known as can be afflicted with postnatally and in case of being afflicted with pre-natally the abdominal cavity and thoracic organ of fetus are oppressed due to fetal abdominal distention leading to fetal death caused by organ dysgenesis. No medical report has yet been published on congenital omental cyst of fetus. This study was conducted on a case of congenital omental cyst of fetus we have experienced in a mother with 16weeks of gestational period and the result is hereby reported along with literally documents.
Abdominal Cavity
;
Fetal Death
;
Fetus
;
Humans
;
Mothers
;
Rare Diseases
4.The reliability of health risk appraisals questionnaire: in SNUH lifetime health-monitoring program.
Seong Ho HA ; Jae Hyun PARK ; Hyun Joo OH ; Cheol Hwan KIM ; Sang Im JEON ; Lack Jin SEONG ; Taiwoo YOO ; Chang Yup KIM
Journal of the Korean Academy of Family Medicine 1992;13(4):354-363
No abstract available.
Health Status Indicators*
;
Surveys and Questionnaires
5.Evaluation of HBs Ag, HCV and HIV Ag-Ab Assays using Bio-Rad Elite Microplate Analyzer.
Sang Hyun HWANG ; Heung Bum OH ; Hyon Suk KIM ; Eun Yup LEE
The Korean Journal of Laboratory Medicine 2006;26(6):436-441
BACKGROUND: In this study, we evaluated the performance of Elite microplate analyzer (Bio-Rad Laboratories, France) and the related assays (ULTRA line) for the detection of hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV). METHODS: Seroconversion panels, HBsAg positive/HBsAg negative (n=99/n=1,422), anti-HCV positive/negative (n=97/n=1,670), and anti-HIV positive/negative (n=112/n=1,704) samples were used to evaluate the performance of Monolisa HBsAg ULTRA, Monolisa HCV Ag-Ab ULTRA, and Genscreen ULTRA HIV Ag-Ab, respectively. The agreement of Elite microplate analyzer with CODA analyzer (Bio-Rad Laboratories, CA, USA) was also evaluated. RESULTS: The detection limit of Monolisa HBsAg ULTRA was 0.034 IU/mL. For Monolisa HBsAg ULTRA, Monolisa HCV Ag-Ab ULTRA, and Genscreen ULTRA HIV Ag-Ab, diagnostic sensitivities were all 100%, diagnostic specificities were 100%, 99.8% and 99.9%, and total CVs (coefficients of variation) were 13.8-17.5%, 3.4-5.2%, and 7.5-9.5%, respectively. The agreement of Elite microplate analyzer with CODA analyzer was 99.5%. CONCLUSIONS: The performance of Elite microplate analyzer and the related assays on analytical sensitivity, precision, early detection, diagnostic sensitivity and specificity was all adequate for a mass screening. However, further large multi-center studies should be performed to validate our results.
Hepacivirus
;
Hepatitis B Surface Antigens
;
Hepatitis B virus
;
HIV*
;
Limit of Detection
;
Mass Screening
;
Sensitivity and Specificity
6.Analysis of Indication and Rate of Cesarean Deliveries at Dongsan Medical Center for Ten Years.
Joon Cheol PARK ; Sang Yup OH ; Dong Ho LEE ; Jeong Ho RHEE ; Jong In KIM
Korean Journal of Perinatology 2003;14(2):183-189
OBJECTIVE: The aim of this study was to evaluate the rate and indications of cesarean delivery. METHODS: All live birth >27weeks at the Dongsan Medical Center, Keimyung University from 1993 to 2002(n=35,891) were retrospectively analyzed of delivery route, indication of cesarean birth, gestational age, and maternal age. RESULTS: Total cesarean rate was 29.0%(10,411/35,891) and primary rate was 16.8%(6,041/35,891). The annual primary cesarean birth rate number was increased gradually. The most common maternal age of cesarean section patients was between 26-30 years(43.7%). The most common gestational age of cesarean section patients was over 36 weeks(87.4%). Abnormal presentation and CPD were the most common indication(19.17%, 1,158/6,041) at primary cesarean deliveries. The third common indication was fetal distress(16.44%, 993/6,041). CONCLUSIONS: Total cesarean rate was increased gradually by increasing the previous section rate as well as the primary section rate. Further evaluation will be needed about the relationship between cesarean deliveries and long term fetal outcome, and the effort for VBAC will be needed.
Birth Rate
;
Cesarean Section
;
Female
;
Gestational Age
;
Humans
;
Live Birth
;
Maternal Age
;
Parturition
;
Pregnancy
;
Retrospective Studies
7.Three Cases of Transient Symptomatic Zinc Deficiency.
Mi Ock KIM ; Sun Young PARK ; Oh Soo KWON ; Kyung Lim LEE ; Own Yup KIM ; Own Jo JUNG ; Sang Hyuk MA
Korean Journal of Pediatric Gastroenterology and Nutrition 1999;2(1):123-129
Transient symptomatic zinc deficiency (TSZD) is clinically similar to acrodermatitis enteropathica. The patients are experienced dermatitis on periorifice and extremities, alopecia, diarrhea, growth retardation, anemia, delayed wound healing and infection. They showed a characteristically rapid response to zinc supplement without recurrence. We report 3 cases of TSZD infants, 2 premature infants with inadequate zinc supply and 1 mature infant with chronic diarrhea.
Acrodermatitis
;
Alopecia
;
Anemia
;
Dermatitis
;
Diarrhea
;
Extremities
;
Humans
;
Infant
;
Infant, Newborn
;
Infant, Premature
;
Recurrence
;
Wound Healing
;
Zinc*
8.Anthropometric Analysis on Facial Profile Alterations Following Augmentation Rhinoplasty with Nasal Tip Plasty.
Hyun Soo OH ; Sang Yoon KANG ; Ki Yup KIM ; Won Yong YANG
Journal of the Korean Society of Aesthetic Plastic Surgery 2010;16(3):144-150
There are various nasal measurement parameters for rhinoplasty, so it is difficult for surgeons to decide which measurements to place more emphasis on. Among many, we searched for measurements that are significantly altered after the augmentation rhinoplasty with nasal tip plasty to figure out which measurements are most required in preoperative preparation. From January, 2006 to July, 2008, a total of 85 patients underwent augmentation rhinoplasty with nasal tip plasty and 40 were selected for comparative analysis of preoperative and postoperative photographs. Among many measurement factors reflecting changes of a face and a nose, we measured and compared following parameters, 1) nasofrontal angle, 2) nasofacial angle, 3) nasolabial angle, 4) nasal tip angle, 5) columella-lobular angle, 6) nasal length to tip projection, 7) alar slope angle, 8) nostril axis angle, 9) lobule-to-nostril ratio before and after operations. The result was analyzed using paired t-test. The measurement parameters most significantly altered after augmentation rhinoplasty with nasal tip plasty were the increase in nasolabial angle, the decrease in nasofacial angle, and the decrease in nostril axis angle. Therefore, surgeons should place more emphasis on these parameters in preoperative planning and postoperative evaluation.
Anthropometry
;
Axis, Cervical Vertebra
;
Humans
;
Hypogonadism
;
Mitochondrial Diseases
;
Nose
;
Ophthalmoplegia
;
Rhinoplasty
;
Succinates
10.Infectious Complications in Renal Transplant Recipients: Changing Epidemiology under Modern Immunosuppression.
Sang Il MIN ; Yang Jin PARK ; Whando RA ; Seong Yup KIM ; Seung Kee MIN ; Myoung Don OH ; Yon Su KIM ; Curie AHN ; Sang Joon KIM ; Jongwon HA
The Journal of the Korean Society for Transplantation 2010;24(3):187-195
BACKGROUND: Immunosuppressive agents with higher potencies, such as tacrolimus and mycophenolate mofetil (MMF), have been introduced and widely accepted in clinical practice. This study evaluated the impact of these newer immunosuppressive drugs on the pattern and timing of post-kidney transplantation infections. METHODS: Data of kidney transplant recipients at the Seoul National University Hospital between January 1990 and November 2005 were analyzed. Recipients were divided into double immunosuppression (double group, n=198), triple immunosuppression including MMF (MMF group, n=253), and azathioprine (AZA, n=184) groups. RESULTS: The MMF group demonstrated higher graft survival and reduced rates of acute rejection within the fifth post-transplant year than both the AZA (P<0.001) and the double (P<0.001) groups. The overall incidence of infection in the first month was significantly higher in the MMF group (2.17/1,000 transplant-days) than in the AZA (0.73/1,000 transplant-days) and double (0.84/1,000 transplant-days) groups (P=0.01, ANOVA), and this was caused by viral infections that were significantly higher in the MMF (1.57/1,000 transplant-days) group than in the AZA (0.54/1,000 transplant-days) and double (0.67/1,000 transplant-days) groups. MMF was identified as a significant risk factor for viral infection (P=0.013; OR, 2.04; 95% CI, 1.16-3.60) in a multivariate logistic regression analysis. CONCLUSIONS: The results suggest that viral infection rates were higher in the MMF group and should be considered the primary source of perioperative infectious complications in MMF-receiving recipients.
Azathioprine
;
Graft Rejection
;
Graft Survival
;
Immunosuppression
;
Immunosuppressive Agents
;
Incidence
;
Kidney
;
Logistic Models
;
Mycophenolic Acid
;
Rejection (Psychology)
;
Risk Factors
;
Tacrolimus
;
Transplants
;
Viruses