Primary hyperparathyroidism is a rare endocrine disease in children. It involves bone and joint, urinary tract, gastrointestinal tract and cardiovascular system. The main cause of these involvement is high level of PTH in serum, resulting in hypercalcemia.An 11 years old male patient who had complained of limping gait since last 18 months, showed typical laboratory and radiological findings of primary hyperparathyroidism. At the ultrasonography, computed tomography and radionuclide scanning, a well defined mass(10 X 15mm) was found on the posterior aspect of the right thyroid lobe. The mass was confirmed histologically as adenoma of parathyroid gland. The patient was successfully treated with subtotal parathyroidectomy and temporal administration of calcium and vitamin D.We report this case of primary hyperparathyroidism with brief review of the literatures.
Adenoma ; Calcium ; Cardiovascular System ; Child ; Endocrine System Diseases ; Gait ; Gastrointestinal Tract ; Humans ; Hyperparathyroidism, Primary ; Joints ; Male ; Parathyroid Glands ; Parathyroidectomy ; Thyroid Gland ; Ultrasonography ; Urinary Tract ; Vitamins

No abstract available.
Adrenal Cortex Hormones* ; Glaucoma*

The fracture of acrylic resin dentures remains an unsolved problem. Therefore, many investigations have been performed and various approaches to strengthening acrylic resin, for example, the reinforcement of heat-cured PMMA resin using glass fibers, have been suggested over the years. The aim of the present study was to investigate the effect of short glass fibers treated with silane coupling agent on the transverse strength of heat-polymerized PMMA denture base resin. To avoid fiber bunching and achieve even fiber distribution, glass fiber bundles were mixed with PMMA powder in conventional mixer whose blade was modified to be blunt. Composite of glass fiber (11micrometer diameter, 3mm & 6mm length, silane treated) and PMMA resin was made. Transverse strength and Young's modulus were estimated. Glass fibers were incorporated with 1%, 3%, 6% and 9% by weight. Plasticity and workability of dough was evaluated. Fracture surface of specimens was investigated by SEM. The results of this study were as follows 1. 6% and 9% incorporation of 3mm glass fibers in the PMMA resin enhanced the transverse strength of the test specimens (p<0.05). 2. 6% incorporation of 6mm glass fibers in the PMMA resin increased transverse strength, but 9% incorporation of it decreased transverse strength (p<0.05). 3. When more than 3% of 3mm glass fibers and more than 6% of 6mm glass fibers were incorporated. Young's modulus increased significantly (p<0.05). 4. Workability decreased gradually as the percentage of the fibers increased. 5. Workability decreased gradually as the length of the fibers increased. 6. In SEM and LM, there was no bunching of fibers and no shortening of fibers.
Denture Bases ; Dentures ; Elastic Modulus ; Glass* ; Plastics ; Polymethyl Methacrylate*

No abstract available.

No abstract available.
Humans ; Students, Medical*

No abstract available.
Abdomen* ; Humans

We experienced a case of primary aldosteronism due to adrenal adenoma. The patient was 45-year old female, whose main complaints were weakness, headache, and fatigue. By use of abdominal CT scan, ultrasonogram, adrenal angiogram and by result of clinical laboratory findings, we conculuded the diagnosis of adrenal adenoma, and confirmed it by surgical and pathologucal findigs. The clinical sympyoms disappeared after left adrenalectomy, and laboratory findings of renin, aldosterone, electrolutes were normalized but hypertension persisted, so she has been managed by antihypertensives.
Adenoma ; Adrenalectomy* ; Aldosterone ; Antihypertensive Agents ; Diagnosis ; Fatigue ; Female ; Headache ; Humans ; Hyperaldosteronism* ; Hypertension* ; Middle Aged ; Renin ; Tomography, X-Ray Computed ; Ultrasonography

No abstract available.
Cryptococcosis* ; Tuberculosis, Pulmonary*

No abstract available.
Adult* ; Cyclosporine* ; Humans ; Nephrosis, Lipoid*

BACKGROUND: Substrates play an important role in the effectiveness of the indirect immunofluro-rescence test. The monkey eaophagus has been known to be a more reliable and reproducible substrate than any other animal substrates for detecting pemphigus vulgaris autoantibodies, but it is quite difficult to get the monkey esophagus in Korea, therefore, we tried to find other substrates which could be substituted for it. OBJECTIVE: We studied to select the substrate which can be the most sensitive, to compare the immunofluorescent sensitivity of various animal substrates and fores,cins for detection of pemphigus autoantibodies, and finally to evaluate the effectiveness of cultured hunan keratinocytes as a substrate for indirect immunofluorescerice. METHOD: With foreskin, guinea pigs, cats, rats, dogs, rabbits and cultured human keratinocytes as substrates, an indirect imrnunofluorescence test was performed to detect pemphigus vulgaris autoantibodies in seven sera from the active patients before treatment and diluted serially from 1:10 to 1:1280 RESULT: We could detect pernphigus autoantibodies in all animal subtrates used in this study except rats and obtain good immunofluorescent results with foreskin, guinea pigs, and cultured human keratinocytes. The results were moderate with dogs, cats, rabbits, and poor with rats. CONCLUSION: We confirm thut cultured human keratinocytes can be a good effective substrate. According to effectiveness, subtrates can be divided into three groups. Foreskin, guinea pigs, and cultured human keratinocytes are included in the good effective substrate group, dogs, cats, and rabbits in the modeate group and rats in the poor substrate group, but we can not find any superiority of substrates within each groups.
Animals ; Autoantibodies* ; Cats ; Dogs ; Esophagus ; Fluorescent Antibody Technique, Indirect* ; Foreskin ; Guinea Pigs ; Haplorhini ; Humans ; Keratinocytes ; Korea ; Pemphigus* ; Rabbits ; Rats