No abstract available.
Antibodies* ; Humans ; Leprosy*

No abstract available.
Heart* ; Thoracic Surgery*

No abstract available.
Penicillins* ; Pneumonia* ; Sepsis* ; Streptococcus pneumoniae* ; Streptococcus*

No abstract available.
Penicillins* ; Pneumonia* ; Sepsis* ; Streptococcus pneumoniae* ; Streptococcus*

Clinical trials were done to obtain ifnormation on the clinical efficacy, tolerance and side effects of a new antihistarnine, Mecloprodine(Tavegyl), in various skin disordetrs. A total of 48 patients suffered from various skin disorders as urticaria, eczema etc. v ere treated with 2mg. daily for 3 days to 15 days according to state of disorders. The results are as follows. 1. Improvement was noticed in 79.2% of total patients(38/48). 2. Tavegyl was efiective in all 8 cases of acute urticaria and most cases(7/8) of urticaria factitia. 3. Among 19 cases of chronic urticaria, improvement was noticed in 13 cases(68. 49). Improvement was alsa noticed in all 6 cases of eczema. 5. Drowsiness and weakness cccurred in 6.2% of cases(3/48).
Clemastine* ; Eczema ; Humans ; Skin ; Sleep Stages ; Urticaria

Kikuchi-Fujimoto's disease (KFD), or histiocytic necrotizing lymphadenitis, is a rare benign and self-limiting disease. KFD are confused with systemic autoimmune disease as they present with localized lymphadenopathy, fever, fatigue, arthritis, leukopenia. Furthermore as KFD can occur associated with other autoimmune disease, we need to diagnose carefully. Here, we describe a case of 27-year-old female patient, diagnosed as KFD, who subsequently developed adult onset Still's disesase (AOSD). As far as we know, this is the first case of KFD with AOSD in Korea.
Adult ; Male ; Female ; Humans

A high incidence of a T cell phenotype of sinonasal lymphomas in other Asian countries has been associated with a high incidence of Epstein Barr virus (EBV) infection. We analyzed 13 sinonasal and 18 Waldeyer's ring lymphomas for the prevalence of EBV encoded RNA (EBER) using a sensitive and specific in situ hybridization. In addition, we examined the relationship of histologic findings and immunophenotype as well as the location of the lymphomas to the presence of EBV. The EBER was detected in each of 12 sinonasal lymphomas with a T cell immunophenotype. One B cell sinonasal lymphoma was EBER negative. Four of 18 Waldeyer's ring lymphomas were positive for EBER, including two T cell lymphomas. Two of 16 B cell Waldeyer's ring lymphomas were EBER positive. Morphologically, 11 of 20 diffuse large cell lymphomas, 2 diffuse mixed small and large cell lymphomas, 2 of 4 immunoblastic lymphomas and 1 lymphoplasmacytic lymphoma were EBER positive. Four follicular large cell lymphomas were EBER negative. A characteristic angiocentric or angiodestructive pattern was found in most T cell lymphomas and EBER positive cases. These findings indicate that EBV infection is more strongly associated with the T cell immunophenotype, angiocentric pattern and sinonasal location of the lymphoma.
Adult ; Aged ; B-Lymphocytes/immunology ; Female ; Herpesviridae Infections/*virology ; Herpesvirus 4, Human/genetics/*isolation & purification ; Human ; Immunophenotyping ; In Situ Hybridization ; Incidence ; Lymphoid Tissue/virology ; Lymphoma, Non-Hodgkin/epidemiology/immunology/mortality/*virology ; Male ; Maxillary Neoplasms/epidemiology/immunology/mortality/*virology ; Middle Age ; Nasopharyngeal Neoplasms/epidemiology/immunology/mortality/*virology ; Nose Neoplasms/epidemiology/immunology/mortality/*virology ; Prevalence ; RNA, Viral/*analysis ; Support, Non-U.S. Gov't ; Survival Rate ; T-Lymphocytes/immunology ; Tonsillar Neoplasms/epidemiology/immunology/mortality/*virology ; Tumor Virus Infections/*virology

Acroosteolysis (AOL) refers to a destructive process involving distal phalangeal shaft while the tuft and base are preserved. It can be a manifestation of various diseases, such as scleroderma, Raynaud's disease, rheumatoid vasculitis, psoriasis, renal osteodystrophy and leprosy. Occupational exposure to polyvinyl chloride polymers, thermal injury, and repetitive mechanical injury can also cause this problem. Although the exact pathogenesis of AOL is uncertain, a unifying theme of vascular and mechanical injury is presented. Recently, we experienced a 32-year-old woman complained of xerophthalmia, zerostomia and polyarthralgia which was diagnosed as Sj6gren syndrome associated with acroosteolysis. After administration of prednisolone, cyclophosphamide and oral bromhexine, subsidence of her symptoms was observed. We report this case with a review of relevant literature.
Acro-Osteolysis* ; Adult ; Arthralgia ; Bromhexine ; Cyclophosphamide ; Female ; Humans ; Leprosy ; Occupational Exposure ; Polymers ; Polyvinyl Chloride ; Prednisolone ; Psoriasis ; Raynaud Disease ; Renal Osteodystrophy ; Rheumatoid Vasculitis ; Sjogren's Syndrome* ; Xerophthalmia

No abstract available.
Female ; Ovary* ; Teratoma*

Purpose: The aim of this study was to investigate the effects of long-term immobilization stress on spermatogenesis and testosterone production in a rat model. Materials and Methods: Thirty randomly selected adult male rats were divided into 6 groups: immobilization stress groups (I, III, V) and control groups (II, IV, VI). In the immobilization stress groups, 15 rats were immobilized in a steel cage for 6 hours per day for 14 days. Groups I and II were sacrificed just after finishing the immobilization session. Groups III and IV were sacrificed after a 1 week resting period. Groups V and VI were sacrificed after a 2 week resting period. The serum concentrations of corticosterone, luteinising hormone (LH), follicle stimulating hormone (FSH) and testosterone were measured. Specimens of the testis were stained with hematoxylin-eosin and Masson's trichrome. Results: Following 2 weeks of immobilization, the serum concentration of corticosterone was significantly increased; whereas, the serum concentrations of LH and testosterone were decreased. However, the serum FSH concentration remained unchanged. After the 1 week resting period, there were significant recoveries in the serum concentrations of corticosterone, LH and testosterone. From the histology of the immobilization group, the mean testicular biopsy score (Johnsen score) was significantly decreased, but the mean value of the seminiferous tubule luminal diameter was significantly increased; whereas, that of the seminiferous tubule diameter remained unchanged. These changes slowly recovered after the resting period. Conclusions: These results suggest that the exposure to long-term immobilization impairs spermatogenesis and androgenic testicular functions in rats.
Adult ; Animals ; Biopsy ; Corticosterone ; Follicle Stimulating Hormone ; Humans ; Immobilization* ; Male ; Models, Animal ; Phenobarbital ; Rats ; Seminiferous Tubules ; Spermatogenesis* ; Steel ; Testis ; Testosterone*