1.Experience of therapeutic plasma exchanges in Seoul National University Hospital.
Tae Hyun UM ; Nam Yong LEE ; Hyo Soon PARK ; Kyou Sup HAN ; Sang In KIM
Korean Journal of Blood Transfusion 1993;4(2):199-205
No abstract available.
Plasma Exchange*
;
Plasma*
;
Seoul*
2.Experience of therapeutic plasma exchanges in Seoul National University Hospital.
Tae Hyun UM ; Nam Yong LEE ; Hyo Soon PARK ; Kyou Sup HAN ; Sang In KIM
Korean Journal of Blood Transfusion 1993;4(2):199-205
No abstract available.
Plasma Exchange*
;
Plasma*
;
Seoul*
3.Modified reduction genitoplasty
Chang Soo KIM ; In Woong UM ; Heuy Yong ANN ; Sang Chul CHUNG ; Hong Sik CHOI
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons 1991;13(2):199-202
No abstract available.
4.Buccal fat pad transfer as a pedicled flap for facial augmentation
Sang Chul CHUNG ; Heui Yong ANN ; Hong Sik CHOI ; In Woong UM ; Chang Soo KIM
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons 1991;13(2):153-159
No abstract available.
Adipose Tissue
;
Surgical Flaps
5.A Case of Neonatal Altoimmune Thrombocytopenia due to Anti-HLA-B7 +1=160 +B61.
Kyou Sup HAN ; Tae Hyun UM ; Myoung Hee PARK ; Yong Won PARK ; Bo Moon SHIN ; Sang Woo KIM
Korean Journal of Blood Transfusion 1994;5(1):45-51
We encountered a case of neonatal altoimmune thrombocytopenia(NAIT) due to anti-HLA-B7+B60+B61. Bilateral cephal hematoma and umbilical hematoma were noted at the time of birth. Purpura developed at the third day. Platelet count was 110,000 at birth and decreased to 66,000/micro liter at the day 4. Prothrombin time and partial prothrombin time were within normal limit. The mother's platelet count was 220,000/micro liter and she had no history of abnormal bleeding. Platelet antibody tests empolying mixed passive hemagglutination and immunofluorescence revealed that the mother's serum was reactive against the platelets from the father and the neonate, but was not reactive with her own platelets. Platelets from eight volunteer group 0 donors were tested with the mother's serum; seven were reactive and one was negative. The positive reactions were lost after chloroquine treatment of platelets. Antigen capture ELISA(ACE) and modified antigen capture ELISA employing monoclonal antibodies against platelet glycoproteins In, IIa, IIb, and IIIa were negative. Mother's serum was tested for lymphocytotoxicity against 49 donor ]ymphocytes and the specificity was found to be anti-HLA-B7+B60+B61. At the 9th day, one unit of platelet concentrate from the mother was transfused and the platelet count of the neonate rose up to 340,000/micro liter. The neonate was discharged at the day of sixteenth and the platelet count remained high thereafter.
Antibodies, Monoclonal
;
Blood Platelets
;
Chloroquine
;
Enzyme-Linked Immunosorbent Assay
;
Fathers
;
Fluorescent Antibody Technique
;
Hemagglutination
;
Hematoma
;
Hemorrhage
;
Humans
;
Infant, Newborn
;
Mothers
;
Parturition
;
Platelet Count
;
Platelet Membrane Glycoproteins
;
Prothrombin Time
;
Purpura
;
Sensitivity and Specificity
;
Thrombocytopenia*
;
Tissue Donors
;
Volunteers
6.Diffuse Pulmonary Meningotheliomatosis: A Case Report.
Jungsuk AN ; Heejung PARK ; Joungho HAN ; Tae Sung KIM ; Yong Soo CHOI ; Moon Seok CHOI ; Sang Won UM
Korean Journal of Pathology 2011;45(Suppl 1):S32-S35
Diffuse pulmonary meningotheliomatosis (DPM) is an extremely rare condition. We herein report a unique case of DPM in a 54-year-old woman with a previous history of hepatocellular carcinoma. A chest computed tomography showed diffuse bilateral nodular infiltration, suggesting miliary spread of metastatic hepatocellular carcinoma. The patient underwent a video-assisted thoracoscopic surgery for diagnostic purposes. The cut surface of the lung specimen showed multiple dispersed small nodules, consisting of variably sized nests or whorls of bland epithelioid cells often along the walls of alveolar septa or in a perivascular network within the alveolar interstitium. The tumor cells showed immunoreactivity for epithelial membrane antigen, vimentin, and progesterone receptor. DPM should be included in the differential diagnosis of diffuse multiple small nodules or a reticular pattern in the radiologic studies.
Carcinoma, Hepatocellular
;
Diagnosis, Differential
;
Epithelioid Cells
;
Female
;
Humans
;
Lung
;
Lung Neoplasms
;
Meningioma
;
Middle Aged
;
Mucin-1
;
Receptors, Progesterone
;
Thoracic Surgery, Video-Assisted
;
Thorax
;
Vimentin
7.Comparison of Enflurane Consumptions and Costs in Low Flow and High Flow Anesthesia.
Jong Kook LEE ; Sang Yong UM ; Chan Jong CHUNG ; Young Jhoon CHIN
Korean Journal of Anesthesiology 1999;37(4):574-579
BACKGROUND: The amount and composition of fresh gas flow affect the consumption of inhalational anesthetics. The purpose of this study was to compare the enflurane consumption and economic aspects of low flow and high flow anesthesia. METHODS: Thirty patients, ASA physical status I or II, aged 20 65 yr., scheduled for gastrectomy under inhalational anesthesia, were studied. The patients were randomly assigned to one of three groups according to the fresh gas flow: O2 500 ml/min (group I); N2O 2 L/min - O2 1 L/min (group II); O2 3 L/min (group III). Anesthesia was maintained in group I by a continuous infusion of liquid enflurane into the inspiratory limb of the breathing circuit, using a syringe pump. In groups II and III, enflurane was administered by a conventional vaporizer. The cumulative dose of liquid enflurane was measured every 10 min during anesthesia. Hemodynamic parameters, inspired and expired enflurane concentrations, and enflurane consumptions were measured. RESULTS: There were no significant differences among the three groups in hemodynamic changes. The enflurane consumption was significantly less in group I than in groups II and III over time (P < 0.05). CONCLUSIONS: Low flow anesthesia offers economic advantages over high flow anesthesia.
Anesthesia*
;
Anesthetics
;
Enflurane*
;
Extremities
;
Gastrectomy
;
Hemodynamics
;
Humans
;
Nebulizers and Vaporizers
;
Respiration
;
Syringes
8.Comparison of Enflurane Consumptions and Costs in Low Flow and High Flow Anesthesia.
Jong Kook LEE ; Sang Yong UM ; Chan Jong CHUNG ; Young Jhoon CHIN
Korean Journal of Anesthesiology 1999;37(4):574-579
BACKGROUND: The amount and composition of fresh gas flow affect the consumption of inhalational anesthetics. The purpose of this study was to compare the enflurane consumption and economic aspects of low flow and high flow anesthesia. METHODS: Thirty patients, ASA physical status I or II, aged 20 65 yr., scheduled for gastrectomy under inhalational anesthesia, were studied. The patients were randomly assigned to one of three groups according to the fresh gas flow: O2 500 ml/min (group I); N2O 2 L/min - O2 1 L/min (group II); O2 3 L/min (group III). Anesthesia was maintained in group I by a continuous infusion of liquid enflurane into the inspiratory limb of the breathing circuit, using a syringe pump. In groups II and III, enflurane was administered by a conventional vaporizer. The cumulative dose of liquid enflurane was measured every 10 min during anesthesia. Hemodynamic parameters, inspired and expired enflurane concentrations, and enflurane consumptions were measured. RESULTS: There were no significant differences among the three groups in hemodynamic changes. The enflurane consumption was significantly less in group I than in groups II and III over time (P < 0.05). CONCLUSIONS: Low flow anesthesia offers economic advantages over high flow anesthesia.
Anesthesia*
;
Anesthetics
;
Enflurane*
;
Extremities
;
Gastrectomy
;
Hemodynamics
;
Humans
;
Nebulizers and Vaporizers
;
Respiration
;
Syringes
9.Effects of Amrinone on Systemic and Pulmonary Arterial Pressure in Infants with Intracardiac Left to Right Shunt.
Sang Yong UM ; Chan Jong CHUNG ; Young Jun CHIN
Korean Journal of Anesthesiology 2000;38(6):1017-1023
BACKGROUND: Amrinone is a nonglycosidic noncatecholamine with both vasodilator and positive inotropic effects that has not been evaluated widely in pediatric patients with intracardiac left to right shunts. The present study was performed to evaluate the hemodynamic effects of amrinone in infants and children with intracardiac left to right shunts. METHODS: Twenty patients (aged 2 months to 24 months) who underwent open heart surgery to correct one or more intracardiac left to right shunts were evaluated. Before cardiopulmonary bypass, a 22 gauge angiocatheter was placed at the main pulmonary artery by surgeons to measure pulmonary arterial pressure. Patients with a mean pulmonary arterial pressure < 25 mmHg were assigned to Group A (n = 10) and > or = 25 mmHg were assigned to Group B (n = 10). Mean systemic arterial pressure (MAP), mean pulmonary arterial pressure (MPAP), central venous pressure (CVP) and heart rate (HR) were measured before loading of amrinone (3 mg/kg), 5 minutes, and 15 minutes after continuous infusion of amrinone (10 microgram/kg). The mean pulmonary arterial pressure to mean systemic arterial pressure ratio (MPAP/MAP) and rates of changes of mean arterial pressure (delta MAP) and mean pulmonary arterial pressure (delta MPAP) were calculated. RESULTS: Amrinone reduced MAP, MPAP, CVP and increased HR. MPAP/MAP increased in Group A but decreased in Group B (P < 0.05). In Group A, delta MAP was significantly greater than that of Group B (P < 0.005). In Group B, delta MPAP was significantly greater than that of Group A (P < 0.005). CONCLUSION: In infants with intracardiac left to right shunts, amrinone reduces MAP, MPAP, CVP and increases HR. Amrinone appears to have a potent vasodilating effect on the pulmonary artery in infants with pulmonary hypertension. However, more hemodynamic measurements such as cardiac output, vascular resistance and doppler echocardiographic study are necessary to evaluate the hemodynamic effects of amrinone precisely.
Amrinone*
;
Arterial Pressure*
;
Cardiac Output
;
Cardiopulmonary Bypass
;
Central Venous Pressure
;
Child
;
Echocardiography
;
Heart Rate
;
Hemodynamics
;
Humans
;
Hypertension, Pulmonary
;
Infant*
;
Pulmonary Artery
;
Thoracic Surgery
;
Vascular Resistance
10.Relationship of TGF-beta1 mRNA Expression and Captopril after PTFE Graft in Rabbit Carotid Artery.
Jun Won UM ; Young Sik KIM ; Suk In JUNG ; Sang Yong CHOI ; Cheung Wung WHANG
Journal of the Korean Society for Vascular Surgery 1999;15(2):195-204
PURPOSE: Intimal hyperplasia (IH) due to vascular smooth muscle cell proliferation is a leading cause of late vascular graft failure. Transforming growth factor-beta1 (TGF-beta1), known to influence smooth muscle cell growth in vascular wall has been subjected for experimental research as a cause of IH. It has been also showed that IH can be mediated by local renin-angiotensin system in vascular intimal injury. Under the assumption that TGF-beta1 and local angiotensin II (ANG II) have a major role as a cause of IH, we carried out this study to see if there are any relationship between intimal hyperplasia and TGF-beta1 mRNA expression, and effect of angiotensin-converting enzyme inhibitor (ACEI) on IH. METHODS: 14 New Zealand White rabbits were subjected for this experiment. The right carotid arteries of 14 rabbits had been bypass grafting with polytetrafluoroethylene. 14 rabbits were allocated into two groups: 7 rabbits had bypass grafting only (graft only) and the other 7 rabbits had bypass grafting with ACEI (graft with ACEI). The rabbits, graft with ACEI were on Captopril (10 mg/kg/day PO) from day of operation to 8 weeks when to harvest. There were patent 9 carotid bypass grafts at harvest, and the studies were performed in patent grafts. Intimal hyperplasia was defined by the intima to media height ratio (IMHR). The mRNA expression of TGF-beta1 was determined by semiquantitative RT-PCR. RESULTS: IMHR of graft with ACEI was lower than that of graft (p<0.05). The mRNA expression of TGF-beta1 in graft with ACEI was lower than that in graft only (p<0.05). In summary, there was evidence that TGF-beta1 is closely related with intimal hyperplasia and there is also relationship between ANG II and TGF-beta1. CONCLUSION: ANG II and TGF-beta1 may mediate intimal hyperplasia of vascular graft, and ACE inhibitor may be a armamentarium for inhibition of intimal hyperplasia in vascular graft procedures.
Angiotensin II
;
Captopril*
;
Carotid Arteries*
;
Cell Proliferation
;
Hyperplasia
;
Muscle, Smooth, Vascular
;
Myocytes, Smooth Muscle
;
Polytetrafluoroethylene*
;
Rabbits
;
Renin-Angiotensin System
;
RNA, Messenger*
;
Transforming Growth Factor beta1*
;
Transplants*