Dermatomyositis is a systemic connective tissue disease affecting the skeletal muscles and skin. Necrotizing cutaneous vasculitis and subsequent diffuse subcutaneous and muscular calcification in patients with dermatomyositis is uncommon and has not been reported. A 23-year-old female with dermatomyositis developed necrotizing cutaneous vasculitis in the knee, elbow, buttock, toe and fingers associated with large ulcer formation. Her left 5th finger was amputated due to massive soft tissue destruction, and her right 5th finger later auto-amputated. Thereafter, she developed small subcutaneous nodules on both wrists, elbows, upper arms, neck, buttocks and thighs. X-ray, computerized tomography and gracilis muscle biopsy confirmed diffuse subcutaneous, fascia and muscular calcifications.
Arm ; Biopsy ; Buttocks ; Connective Tissue Diseases ; Dermatomyositis ; Elbow ; Fascia ; Female ; Fingers ; Humans ; Knee ; Muscle, Skeletal ; Muscles ; Neck ; Skin ; Thigh ; Toes ; Ulcer ; Vasculitis ; Wrist ; Young Adult

No abstract available.
Aortic Valve ; Aortic Valve Insufficiency