1.Clinical Characteristics and Use of Psychotropic Agents among HIV-Infected/AIDS Patients Referred for Psychiatric Consultation.
Sang Ho SHIN ; Hyun Chung KIM ; So Young YOO ; Hyoung Shik SHIN ; Sung Doo WON ; So Hee LEE
Korean Journal of Psychosomatic Medicine 2014;22(1):31-39
OBJECTIVES: This study aimed to investigate the psychiatric status of HIV-infected/AIDS inpatients in a general hospital over the past 2.5 years. METHODS: A retrospective chart review was conducted of psychiatric consultations performed between January 1, 2011, and July 30, 2013. The records of 97 HIV-infected/AIDS patients were analyzed. These included a total of 282 psychiatric consultations. RESULTS: Of the 97 patients, 91(93.8%) were male, the mean age was 48 years, and mean number of consultations was 2.8. Depressed mood was reported in 102 consultations(23.8%), insomnia in 60(14.0%), and anxiety in 31(7.2%). Psychiatric disorders diagnosed on initial consultation included depressive disorder(37 patients ; 37.0%), cognitive disorder(11 ; 11.0%), and delirium(9 ; 9.0%). Recommended psychotropic medication included Lorazepam(99 ; 17.2%), Escitalopram(90 ; 15.7%), and Quetiapine(84 ; 14.6%). CONCLUSIONS: The main complaints of HIV-infected/AIDS patients were depressed mood, insomnia, and suicidal ideation(including suicide attempts). In total, 85(93.3%) patients of those consulted were diagnosed as meeting the criteria for a psychiatric condition. However, considering that only 16.9% of patients consulted received follow-up treatment, longitudinal research is needed to examine the influence of psychiatric disorders on the transmission of HIV-infection/AIDS, as well as on prognosis and treatment adherence.
Anxiety
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Follow-Up Studies
;
HIV
;
Hospitals, General
;
Humans
;
Inpatients
;
Male
;
Prognosis
;
Referral and Consultation
;
Retrospective Studies
;
Sleep Initiation and Maintenance Disorders
;
Suicide
2.A study on the T lymphocyte subsets, plasma neopterin and serum lgE in patients with atopic dermatitis.
Seon Kyo SUH ; Moon kyu KIM ; So Won KIM ; Jae Bok JUN ; Sang Lip CHUNG
Korean Journal of Dermatology 1993;31(6):877-883
BACKGROUND: Many physiologic, pharmacologic and immunologic abnormalities were reported in atopic dermatitis but the cause and pathogenesis of the disease remain obscure. OBJECTIVE: This study was done to investigate the systemic immunologic abnormalities in atopic dermatitis. METHOD: To evaluate the cell mediated immunity, me quantified pei ipheral blood T lymphocytes and their subsets, using flow cytometery, and assessed plasma neopteiin levels by means of radioimmunoassay. To evaluate the abnormal humoral immunity, we assessed the serum IgE levels by means of enzyme-immunoassay. RESULTS: Mean proportions of peripheral blood T lymphocytes and, heir subsets in atopic Dermatitis patients were within normal limits. Hut the suppvessor/cytotoxic T lyrphocytes(T8) were significantly decreased in the group of se"ere atopic dermatitis compared with the group of mild atopic dermatitis(P<0.05). Plasma neopterin lervels in the group of atopic dermatitis were found to be significantly elevated as compared vith the control group(P<0.01), but no significant cifference was found between the mild and severe group of atcpic dermatitis(P>0.05). Mean serum IgE levels in the patients with atopic dermatitis were higher than reference value. But there was no significant difference between the mild and severe atopic dermatitis group. Serum IgE levels ivere negatiiely correlated with T8(r=-0.3774, P<0.05) and positively with T4/T8 ratio(r =0.5007, P<0.05). Conclusions : These data;uggest that the atopic der matitis has abr ormalities in cell mediated immunity as well as elevated IgE level.
Dermatitis, Atopic*
;
Humans
;
Immunity, Cellular
;
Immunity, Humoral
;
Immunoglobulin E
;
Neopterin*
;
Plasma*
;
Radioimmunoassay
;
Reference Values
;
T-Lymphocyte Subsets*
;
T-Lymphocytes
3.Histologic evaluation and removal torque analysis of nano- and microtreated titanium implants in the dogs.
Seok AHN ; Mong Sook VANG ; Hong So YANG ; Sang Won PARK ; Hyun Pil LIM
The Journal of Advanced Prosthodontics 2009;1(2):75-84
STATEMENT OF PROBLEM: A number of studies about the nano-treated surfaces of implants have been conducting along with micro-treated surfaces of implants. PURPOSE: The purpose of this study was to get information for the clinical use of nano-treated surfaces compared with micro-treated surfaces by measuring removal torque and analyzing histological characteristics after the placement of various surface-treated implants on femurs of dogs. MATERIAL AND METHODS: Machined surface implants were used as a control group. 4 nano-treated surface implants and 3 micro-treated surface implants [resorbable blast media surface (RBM), sandblast and acid-etched surface (SAE), anodized RBM surface] were used as experimental groups. Removal torque values of implants were measured respectively and the histological analyses were conducted on both 4weeks and 8weeks after implant surgery. The surfaces of removed implants after measuring removal torque values were observed by scanning electron microscopy (SEM) at 8 weeks. RESULTS: 1. Removal torque values of the nano-treated groups were lower than those of micro-treated groups. 2. Removal torque values were similar in the anodized RBM surface groups. 3. On the histological views, there was much of bone formation at 8 weeks, but there was no difference between 4 and 8 weeks, and between the types of implant surfaces as well. CONCLUSION: It is suggested that implant topography is more effective in removal torque test than surface chemistry. To get better clinical result, further studies should be fulfilled on the combined effect of surface topography and chemistry for the implant surface treatments.
Animals
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Dogs
;
Femur
;
Microscopy, Electron, Scanning
;
Osteogenesis
;
Titanium
;
Torque
4.Effect of Splenectomy in Adult Patients with Idiopathic Thrombocytopenic Purpura (ITP).
Chul Won CHOI ; So Young YOON ; Chang Won PAEK ; In Keun CHOI ; Jae Hong SEO ; Byung Soo KIM ; Sang Won SHIN ; Yeul Hong KIM ; Jun Suk KIM
Korean Journal of Hematology 1999;34(4):513-520
No abstract available.
Adult*
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Humans
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Purpura, Thrombocytopenic, Idiopathic*
;
Splenectomy*
5.The Effect Of Temporary Cement And Desensitizer On The Bond Strength Of Luting Cements.
Se Na SUN ; Hong So YANG ; Sang Won PARK
The Journal of Korean Academy of Prosthodontics 2002;40(4):335-343
This study investigated the effect of temporary cement and desensitizer on the bond strength of luting cements. Total 96 dentin specimens were divided into two groups with and without temporary cementation. For temporary cement-treated group, specimens were cemented with Temp-bond(R) and all specimens were stored in distilled water at 37 celsius degrees for 7 days. Each group was further divided into 3 subgroups with Gluma(R), One-step(R) application and without desensitizer. After desensitizer application, Ni-Cr specimens were luted to dentin surface with Panavia-F(R) and Vitremer(R). Specimens were placed in distilled water at 37 celsius degrees for 24 hours and shear bond strength between metal and dentin was measured by a universal testing machine. The results were as follows: 1. In Panavia-F(R) cemented groups, the combination of One-step(R) without temporary cement showed the greatest strength. Among the desensitizer types, One-step(R) showed the highest bond strength, followed by No-desensitizer, Gluma(R). 2. In Vitremer(R) cemented groups, the combination of no temporary cement and without desensitizer showed the greatest bond strength. Among the desensitizer types, No-desensitizer group showed the highest bond strength. 3. The use of Gluma(R) significantly reduced the shear bond strength in Panavia-F(R) and Vitremer(R) groups. 4. All temporary cement-treated groups showed a significant lower shear bond strength than without temporary cement groups. 5. Desensitizer application significantly influenced the bond strength of the resin cement and resin modified glass ionomer cement.
Cementation
;
Dentin
;
Glass Ionomer Cements
;
Resin Cements
;
Water
6.Shear bond strength of composite resin to titanium according to various surface treatments.
Seung Yun LEE ; Mong Sook VANG ; Hong So YANG ; Sang Won PARK ; Ha Ok PARK ; Hyun Pil LIM
The Journal of Advanced Prosthodontics 2009;1(2):68-74
STATEMENT OF PROBLEM: When veneering composite resin-metal restoration is prepared, the fact that bond strength between Ti and composite resin is relatively weak should be considered. PURPOSE: The purpose of this study is to evaluate the shear bond strength between the veneering composite resin and commercial pure (CP) Ti / Ti-6Al-4V alloy according to the method of surface treatment. MATERIAL AND METHODS: The disks were cast by two types of metal. Their surfaces were treated by sandblasting, metal conditioner, TiN coating and silicoating respectively. After surface treatment, the disks were veneered by composite resin (Tescera(TM), Bisco, USA) which is 5 mm in diameter and 3 mm in thickness. The specimens were stored in water at 25degrees C for 24 hours, and then evaluated for their shear bond strength by universal testing machine (STM-5(R), United Calibration, USA). These values were statistically analyzed. RESULTS: 1. All methods of surface treatment were used in this study satisfied the requirements of ISO 10477 which is the standard of polymer-based crown and bridge materials. 2. The metal conditioner treated group showed the highest value in shear bond strength of CP Ti, silicoated group, TiN coated group, sandblasted group, in following order. 3. The silicoated group showed the highest value in shear bond strength of Ti-6Al-4V alloy, metal conditioner treated group, sandblasted group, TiN coated group, in following order. CONCLUSION: Within the limitations of this study, all methods of surface treatment used in this study are clinically available.
Alloys
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Calibration
;
Collodion
;
Crowns
;
Tin
;
Titanium
;
Water
7.Primary Intraosseous Meningioma.
Won Sang CHO ; So Hyang IM ; Chang Wan OH
Journal of Korean Neurosurgical Society 2005;37(3):238-240
Meningioma is usually known to occur stuck to the dura mater, but extradural meningioma occurs rarely. Most of the extradural meningiomas are located in the head and neck and we report a case of the primary intraosseous meningioma in the orbit. A 50-year old woman presented with the left eye hyperemia and exophthalmos. Neuroimaging modalities showed hyperostosis at the left sphenoid and orbital wall. On microscopic view, spindle cells and psammoma bodies between the woven bones were observed. The origin of the intraosseous meningioma is explained with various potent possibilities and differential diagnosis thoroughly explored.
Diagnosis, Differential
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Dura Mater
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Exophthalmos
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Female
;
Head
;
Humans
;
Hyperemia
;
Hyperostosis
;
Meningioma*
;
Middle Aged
;
Neck
;
Neuroimaging
;
Orbit
8.A Case of Parinaud Syndrome After Intracranial Hemorrhage.
So Yeon LEE ; Sang Won YOON ; Sung Mo KANG
Journal of the Korean Ophthalmological Society 2009;50(1):172-175
PURPOSE: To report one case of Parinaud syndrome after intracranial hemorrhage. CASE SUMMARY: A 45-year-old man visited our emergency department complaining of right-sided weakness and right-sided hypoesthesia. Intracranial hemorrhage in the left thalamus and intraventricular hemorrhage were noted upon brain computed tomography, and the patient was admitted to the department of neurosurgery. He complained of diplopia and upgaze palsy, and he was referred to the department of ophthalmology. The patient exhibited convergence-retraction nystagmus, light-near dissociation and vertical gaze limitation within 15 degrees. The best-corrected visual acuity of both eyes was 20/20, but convergence-retraction nystagmus and light-near dissociation still remained. Upgaze palsy was also not improved. CONCLUSIONS: Once symptoms manifest, Parinaud syndrome does not resolve except in patients with hydrocephalus. If the findings persist for more than 6 months, the likelihood of complete resolution is very small. We reported a case of typical Parinaud syndrome with upgaze palsy, convergence-retraction nystagmus and light-near dissociation after thalamic and intraventricular hemorrhage.
Brain
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Diplopia
;
Dissociative Disorders
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Emergencies
;
Eye
;
Hemorrhage
;
Humans
;
Hydrocephalus
;
Hypesthesia
;
Intracranial Hemorrhages
;
Middle Aged
;
Neurosurgery
;
Ocular Motility Disorders
;
Ophthalmology
;
Paralysis
;
Thalamus
;
Visual Acuity
9.Immunohistochemical Study of p53 and E-cadherin Proteins in Prostate Carcinoma.
Lee So MAENG ; Won Il KIM ; Kyo Young LEE ; Young Shin KIM ; Chang Suk KANG ; Sang In SHIM
Korean Journal of Pathology 1998;32(3):215-221
Considerable controversy exists concerning the value of histomorphological data in the assessment of the malignant potential of prostate carcinomas. Mutations in the p53 gene resulting in the accumulation of altered p53 proteins with prolonged half-life have been found in a large variety of human malignancies. E-Cadherin is a specific epithelial cell-to- cell adhesion molecule which has previously been found to be expressed in well-differentiated non-invasive carcinoma cell lines, but it is lost in many poorly differentiated invasive cell lines. We performed immunohistochemical staining of p53 and E-cadherin in formalin fixed paraffin embedded tissues of 58 primary prostatic carcinomas. The expression rates of p53 and E-cadherin proteins in prostate carcinoma were positive in 15.5% and 44.8% of the cases, respectively. Histologically high-grade prostate carcinoma shows an increased expression of the p53 protein and a decreased one of the E-cadherin protein (P<0.05). The expression rates of the E-cadherin protein in prostate carcinoma decreased significantly according to the higher clinical stages and PSA levels (P<0.05). There was no accordance between the expression rate of p53 and E-cadherin. There were no significant correlation between each of the clinical stages and the expression rate of p53 protein or the PSA levels and the expression rates of p53 protein (P<0.05). Based on the present study, the expression of p53 and down regulation of E-cadherin are correlated with tumor progression and metastasis, and may be a useful prognostic factor in prostate carcinoma.
Cadherins*
;
Cell Adhesion
;
Cell Line
;
Down-Regulation
;
Formaldehyde
;
Genes, p53
;
Half-Life
;
Humans
;
Neoplasm Metastasis
;
Paraffin
;
Prostate*
10.The effect of gender on EC50 of remifentanil to prevent pain during injection of microemulsion propofol.
Bo Won LEE ; Sang Hun KIM ; Keum Young SO
Korean Journal of Anesthesiology 2012;63(6):504-509
BACKGROUND: Propofol injection pain is an unpleasant experience to patients and its prevalence can be influenced by age and gender. We determined the half maximal effective concentration (EC50) of remifentanil for preventing the microemulsion propofol injection pain in the male and female adult groups. METHODS: After institutional review board approval, a total of 60 patients were assigned into 2 groups depending on their gender: group M (male, 20-65 yr) and group F (female, 20-65 yr). Anesthesia was induced with propofol and remifentanil, by a target-controlled infusion. Target effect-site concentration (Ce) of propofol and remifentanil for the first patient started at 4.0 ug/ml and 4.0 ng/ml. Ce of remifentanil for each subsequent patient was determined by the response of the previous patient by the Dixon's up-and-down method (DUDM) with an interval of 0.2 ng/ml. After equilibration of plasma and effect site remifentanil concentration, propofol was administered, and the pain responses were observed. RESULTS: The remifentanil EC50 was 3.8 +/- 0.2 and 2.7 +/- 0.2 ng/ml in groups M and F, respectively, by DUDM. From Probit regression model, the remifentanil EC50 was 3.7 (3.0-4.3) and 2.7 (1.8-2.9) ng/ml in groups M and F, respectively. CONCLUSIONS: The remifentanil EC50 for preventing the moderate to severe injection pain of propofol was higher in males than in females.
Adult
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Anesthesia
;
Ethics Committees, Research
;
Female
;
Gender Identity
;
Humans
;
Male
;
Piperidines
;
Plasma
;
Prevalence
;
Propofol