1.Specific Antibody Response in House Dust Mite Asthmatics on Immunotherapy.
Won Sup SHIN ; Bub Sung KIM ; Sang Il LEE
Journal of the Korean Pediatric Society 1989;32(9):1282-1287
No abstract available.
Antibody Formation*
;
Dust*
;
Immunotherapy*
;
Pyroglyphidae*
3.A Case of Lichen Nitidus Coexisted with Molluscum Contagiosum.
Deok Yong SHIN ; Sang Dong KIM ; Dae Won KOO
Korean Journal of Dermatology 1999;37(1):125-127
Lichen nitidus is an uncommon chronic dermatosis characterized by its typical clinical and histopathologic findings and has rarely been described in association with other diseases. We observed a patient with an association of lichen nitidus and molluscum contagiosum, which to the best of our knowledge has not been previously reported in the literature. It remains to be further studied about a possible pathogenesis of lichen nitidus secondary to some viral infections such as molluscum contagiosum, etc.
Humans
;
Lichen Nitidus*
;
Lichens*
;
Molluscum Contagiosum*
;
Skin Diseases
4.The Study of Sweat and Serum Carcinoembryonic Antigen Values in Healthy Subjects.
Ho Cheol SHIN ; Sang Won KIM ; Dong Seok KIM
Korean Journal of Dermatology 1994;32(6):1005-1010
BACKGROUND: The positive reactions of carcinoembryonic antigen(CEA) show varying degrees in the tissue of all sweat gland neoplasms by immunohistochemistry. The CEA secreted from sweat glands presents a high value, compared with that of serum. OBJECTIVE: The study was to evaluate the sweat CEA value in relation to serum CEA value by sex, smoking status and blood type in healthy subjects. METHOD: Fifty-two healthy subjects(M : 43, F :9) aged 21-30, participated in the study. 2ml sweat was collected from the face and chest after intense exercises and 3ml blood was collected from their antecubital veins. Roche Core CEA enzyme immunoassay was used for the measurement of sweat and serum CEA. RESULTS: Sweat CEA values were 102.0+4100.5ng/ml in males and 70.6+458.5ng/ml in females, with their mean valueof 96.6+/-94.9ng/ml. Sweat CEA values were 108.3+/-103.5ng/ml in 27 smokers and 83.9+/-84.8ng/ml in 25 nonsmokers(p>0.05, t-test). Sweat CEA values were higher among the males and the smokers. Serum CEA values were 2.5+/-1.7ng/ml in males and 1.6+/-0.8ng/ml in females, with its mean value of 2.4+/-1.6ng/ml. There was no difference between serum values of smokers and nonsmokers. Sweat CEA values were about 40 times higher than those of serum, with no correlation of sweat and serum CEA(correlation coefficient=-0.16, P>0.05). In the blood type study, sweat CEA values were 123.1+/-131.8ng/ml in A type and 66.1+/-55.0ng/ml in B type(P>0.05), whereas serum CEA values were higher in AB type and lower in O type(P<0.05, ANOVA). CONCLUSION: Sweat CEA values are extraordinarily high in contradistinction to serum. Sweat CEA values are not affected by sex, smoking status and blood type. There seems to be no association between CEA values of sweat and serum.
Carcinoembryonic Antigen*
;
Exercise
;
Female
;
Humans
;
Immunoenzyme Techniques
;
Immunohistochemistry
;
Male
;
Smoke
;
Smoking
;
Sweat Gland Neoplasms
;
Sweat Glands
;
Sweat*
;
Thorax
;
Veins
5.A case of Kostmann syndrome.
Won Sup SHIN ; Sang Woo KIM ; In Kee PAIK
Journal of the Korean Pediatric Society 1989;32(11):1568-1573
No abstract available.
6.Endoscopic Foreign Body Extraction of Upper Gastrointestinal Tract.
Won Chang SHIN ; Sang Min SHIN ; Young Ho KIM ; Kwan Yop KIM
Korean Journal of Gastrointestinal Endoscopy 1994;14(2):171-174
This is a retrospective review of our experience with endoscopic extraction of 20 cases of foreign body on the upper gastrointestinal tract at sanggye paik hospital from Oct. 1989 to Nov. 1993. Among 20 cases, 3 cases were under 5years of age and 17 cases were over 27years of age. 9 cases (45%) were located in the esophagus, 8 cases (40%) were in the stomach and 3 cases (15%) were in the duodenum. All children (100%) have true foreign body, almost of all adults (82%) have food-related foreign body. Dysphagia with chest pain or vomiting was the most common symptom in the esophageal foreign body. Epigastric pain and vomiting or hematemesis were common symptoms in the stomach or duodenal foreign body, All of the esophageal foreign body (100%) were extracted within 72 hours, most of all (91%) stomach and duodenal foreign body were extracted after 72 hours.
Adult
;
Chest Pain
;
Child
;
Deglutition Disorders
;
Duodenum
;
Esophagus
;
Foreign Bodies*
;
Hematemesis
;
Humans
;
Retrospective Studies
;
Stomach
;
Upper Gastrointestinal Tract*
;
Vomiting
7.Ictal Hyperperfusion of Cerebellum and Basal Ganglia in Temporal Lobe Epilepsy: SPECT Subtraction.
Won Chul SHIN ; Seung Bong HONG ; Woo Suk TAE ; Dae Won SEO ; Sang Eun KIM
Korean Journal of Nuclear Medicine 2001;35(1):12-22
PURPOSE: The ictal perfusion patterns of cerebellum and basal ganglia have not been systematically investigated in patients with temporal lobe epilepsy (TLE). Their ictal perfusion patterns were analyzed in relation with temporal lobe and frontal lobe hyperperfusion during TLE seizures using SPECT subtraction. MATERIALS AND METHODS: Thirty-three TLE patients had interictal and ictal SPECT, video-EEG monitoring, SPGR MRI, and SPECT subtraction with MRI co-registration. RESULTS: The vermian cerebellar hyperperfusion (CH) was observed in 26 patients (78.8%) and hemispheric CH in 25 (75.8%). Compared to the side of epileptogenic temporal lobe, there were seven ipsilateral hemispheric CH (28.0%), fifteen contralateral hemispheric CH (60.0%) and three bilateral hemispheric CH (12.0%). CH was more frequently observed in patients with additional frontal hyperperfusion (14/15, 93.3%) than in patients without frontal hyperperfusion (11/18, 61.1%). The basal ganglia hyperperfusion (BGH) was seen in 11 of the 15 patients with frontotemporal hyperperfusion (73.3%) and 11 of the 18 with temporal hyperperfusion only (61.1%). In 17 patients with unilateral BGH, contralateral CH to the BGH was observed in 14 (82.5%) and ipsilateral CH to BGH in 2 (11.8%) and bilateral CH in 1 (5.9%). CONCLUSION: The cerebellar hyperperfusion and basal ganglia hyperperfusion during seizures of TLE can be contralateral, ipsilateral or bilateral to the seizure focus. The presence of additional frontal or basal ganglia hyperperfusion was more frequently associated with contralateral hemispheric CH to their sides. However, temporal lobe hyperperfusion appears to be related with both ipsilateral and contralateral hemispheric CH.
Basal Ganglia*
;
Cerebellum*
;
Epilepsy, Temporal Lobe*
;
Frontal Lobe
;
Humans
;
Magnetic Resonance Imaging
;
Perfusion
;
Seizures
;
Temporal Lobe*
;
Tomography, Emission-Computed, Single-Photon
8.Antihypertensive Effect of Captopril on Essential Hypertension.
Won Chang SHIN ; Ki Hwan KIM ; Suck Koo CHOI ; Won Sang YOO
Korean Circulation Journal 1988;18(1):145-151
The antihypertensive effect of captopril was evaluated in 15 patients with mild to moderate essestial hypertension(Mean age : 55, Mean blood pressure : 171/102mmHg). Captopril was administered 25 to 50mg twice daily with or without hydrochlorothiazide by mouth according to our protocol which was presented in the text. All the patients were followed up to 12 weeks. Captopril with or without hydrochlorothiazide significantly lowered the systolic and diastolic pressure in almost all patients. The mean systolic and diastolic pressure were reduced to 134/86mmHg(-37/-16mmHg ; -22/-16%)(p<0.001). Heart rate did not change significantly. No unwanted effects were observed. We conclude captopril has exellent antihypertensive effect in most patients with mild to moderate essential hypertension.
Blood Pressure
;
Captopril*
;
Heart Rate
;
Humans
;
Hydrochlorothiazide
;
Hypertension*
;
Mouth
9.An Experience of High Dose Intravenous Immunoglobulin Therapy in Refractory Evans Syndrome.
Hee Sup KIM ; Won Sup SHIN ; Sang Il LEE ; Sang Woo KIM
Journal of the Korean Pediatric Society 1990;33(5):701-707
No abstract available.
Immunization, Passive*
;
Immunoglobulins*
10.A clinical study of histiocytosis syndrome.
Hye Yong LEE ; Chul Hee CHUNG ; Won Suk SUH ; Sang Mann SHIN ; Sang Jhoo LEE
Journal of the Korean Pediatric Society 1993;36(10):1417-1425
We made a clinical study on 10 cases of histiocytosis syndrome who had been admitted to the pediatric department of Soon Chun Hyang University Hospital from Jan. 1982 to Dec. 1991. The results were obtained as follows 1) The sex incidence revealed male predominance with the ratio 4:1. 2) Among 10 cases, 4 cases were classified as eosinophilic granuloma, 1 case as Letterer-Siwe disease, 1 case as linfection associated hemophagocytic syndrome and 4 cases as malignant histiocytosis. 3) The mean age of symptom onset was 4 and 7/12 years in all disease group. 4) The common clinical symptoms and signs at dignosis were dyspnea, mass, pain on lower extremities and fever. 5) The most common organ involved among 9 organ systems was liver-spleen and the number of organ systems involved were 1 in 3 2 ases(30%), 3 in 2 cases(20%), 8 in 2 cases (20%) and 6, 7 and 10 organs in each 1 case. 6) The abnormal hematologic findings (Hb; 10g/dl and/or WBC; 4,000/mm3 and/or PLT; 100,000/mm3) were found in 6 cases. 7) Low serum albumin was found in 2 cases. Results of blood culture were Pseudomonas aeruginosae and Salmonella typhi in each 1 case. 8) The common findings on tissue biopsy were histiocytic proliferation and infiltration. 9) 4 patients of MH who recieved chemotherapy, a combination of adriamycin, vincristine, cyclophosphamide and prednisone were given in a total of four courses every 2 weeks ad induction therapy. When complete response was attained, a combination of adriamycin, vincristine, prednisone (AOP) and cyclophosphamide, vincristine, prednisone(COP) was administered alternately every 4 weeks as maintenance therapy for 6-64 months. 10) Among 4 patiens of MH who recieved chemotherapy, 1 patient was lost during induction chemotherapy, for 1 day.2 patients expired during induction chemotherapy, for 1 month, 1 patient expired during maintenance chemotherapty, for 8months, Eosinophilic granuloma cases (3) were recieved currettage and no recurrence. IAHS case due to typhoid fever was improved spontaneously.
Biopsy
;
Cyclophosphamide
;
Doxorubicin
;
Drug Therapy
;
Dyspnea
;
Eosinophilic Granuloma
;
Fever
;
Histiocytic Sarcoma
;
Histiocytosis*
;
Histiocytosis, Langerhans-Cell
;
Humans
;
Incidence
;
Induction Chemotherapy
;
Lower Extremity
;
Lymphohistiocytosis, Hemophagocytic
;
Male
;
Prednisone
;
Pseudomonas aeruginosa
;
Recurrence
;
Salmonella typhi
;
Serum Albumin
;
Typhoid Fever
;
Vincristine