No abstract available.
Anencephaly* ; Autopsy*

We developed an animal model to recreate the condition of an open fracture in communication with the maxillary sinus. We then studied wound healing of the sinus wall structures following fracture in the presence of autogenous bone and alloplastic implant. This model is designed to simulate the repair of an orbital floor fracture in humans. The New Zealand White rabbit was used as the animal model. Standardized 8mm defects were made bilaterally in the maxillary sinuses to include bone and mucosa in 36 rabbits. Two different implants and autogenous calvarial bone graft were placed in the soft-tissue pockets to obturate the defects, exposing one surface of the implant to the open sinus. Medpor porous polyethylene, silicone and calvarial bone implant were compared. Animals were killed at 1, 2 and 8 weeks after implantation. Gross examination of the specimens for the amount of mucosal closure and implant tissue fixation was performed. Histological sections were evaluated for bone and soft-tissue morphology juxtaposed to the implant. Complete closure of the mucosal defect was demonstrated with each type of implant. Medpor implants showed both vascular and soft-tissue ingrowth into pores by week 1. Bone ingrowth was seen by week 2. Closure of the Medpor obturated defects occurred more rapidly than in the silicone group. The Medpor implants and calvarial bone demonstrated bone and soft-tissue fixation, callus formation and maturation, while mature overlying mucosa was reconstituted over the defects. Silicone implants demonstrated a fibrous tissue reaction within 1 week of implantation and they never became fixed to bone or soft tissue. Maxillary sinus wall regeneration occurred in all defects. This study supports clinical observations of maxillary sinus wall regeneration in humans.
Animals ; Bony Callus ; Fractures, Open ; Humans ; Maxillary Sinus ; Models, Animal ; Mucous Membrane ; New Zealand ; Orbit ; Polyethylene ; Rabbits ; Regeneration ; Silicones ; Tissue Fixation ; Transplants ; Wound Healing

No abstract available.
Leukemia* ; Skin*

No abstract available.
Epidermolysis Bullosa* ; Epidermolysis Bullosa, Junctional*

Menetrier's disease is a rare disease characterized by the presence of large rugal folds involving part or all of the stomach. Patients with hypertrophic gastropathy often have distressing abdominal symptoms, weight loss and edema due to gastric protein loss. The 48-year-old male patient was admitted to the Hangang Sacred Heart Hospital with cheif complaints of indigestion and epigastric pain. The diagnosis of Menetriers disease is established by radiologic, endoscopic, and pathologic examination. He was treated with soft diet, antacid, H2- receptor antagonist, and IV albumin. We report a case of Menetriers disease with brief review of literatures.
Diagnosis ; Diet ; Dyspepsia ; Edema ; Gastritis, Hypertrophic* ; Heart ; Humans ; Male ; Middle Aged ; Rare Diseases ; Stomach ; Weight Loss

PURPOSE: Erectile dysfunction (ED) is associated and might be one of the first signs of cardiovascular disease (CVD). We aimed to assess whether men with vasculogenic ED have an increased risk of CVD by evaluating the relationship between erectile function and the intima-media thickness (IMT) of the common carotid arteries. MATERIALS AND METHODS: A total of 40 men were divided into 4 groups according to their erectile function as evaluated by the International Index of Erectile Function (IIEF)-15 and the presence of vascular risk factors (VRF). The risk free (RF) group (n=10) included men with ED and no evidence of VRF, the low-risk (LR) group (n=10) included the vasculogenic ED subjects who were overweight or dyslipidemic, and high-risk (HR) group (n=10) consisted of ED subjects with hypertension or diabetes. An age-matched healthy group without ED served as the control (n=10). Blood pressure, height, weight, the lipid profile and the IMT of the carotid arteries were evaluated. RESULTS: The control group and the vasculogenic ED groups showed significant differences in the IIEF scores and IMT (p<0.05). Spearman's test of the entire subjects revealed a significant correlation between the severity of ED and IMT (p<0.01), which was not present in the control group (p=0.523). However, a significant correlation of the severity of ED and IMT was found in the groups with ED (p<0.05). In addition, the evaluated parameters of the control group and the RF group revealed no significant difference except for the IIEF scores. CONCLUSIONS: Our results suggest that ED might be a prodrome of cardiovascular diseases. Thus, screening on cardiovascular risk factors and taking preventive measures are considered in ED patients, especially if the ED is severe.
Blood Pressure ; Cardiovascular Diseases* ; Carotid Arteries ; Carotid Artery, Common ; Erectile Dysfunction* ; Humans ; Hypertension ; Male ; Mass Screening ; Overweight ; Risk Factors

PURPOSE: To evaluate the clinical correlation between penile size and prostatic volume. MATERIALS AND METHODS: A total of 196 men were included in this study, 96 patients diagnosed as benign prostataic hyperpalsia(BPH, mean age: 67.2+/-18.8) by transurethral ultrasonography(TRUS), and 100 healthy volunteers(mean age: 48+/-16.2). The stretched penile length and penile circumference were measured by one examiner. We compared penile size with prostatic volume. BPH patients were classified as group I(30~39 ml), group II(40~49 ml) and group III(above 50 ml) by prostatic volume. RESULTS: For penile length and penile circumference, the mean values were 12.3+/-2.0 cm and 9.1+/-1.1 cm in group I, 12.6+/-2.2 cm and 9.2+/-1.0 cm in group II, 13.9+/-2.7 cm and 9.8+/-1.2 cm in group III, and 12.3+/-1.3 cm and 9.0+/-1.2 cm in control group, respectively. Compared to the control group, penile size was significantly higher in group III(p <0.05). CONCLUSIONS: Larger prostatic volume, especially above 50 ml, is associated with a significant increase in penile size.
Humans ; Male

The purpose this study was to investigate the variations of the soft tissue profile contour in relation to the skeletal patterns and to confirm the correlation of soft tissue angles to the sagittal or vertical skeletal elements. Lateral cephalograms of 79 cases which were older than 17 years in age, were traced and statistically analyzed. The obtained results were as follows : 1. Nasolabial angle, interlabial angle, lower lip angle, mentolabial angle, symphyseal angle showed the significant differences between skeletal Class II and skeletal. Class III group, but nasofrontal, upper lip, mentolavbial, and symphyseal angles showed the significant differences between high angle low angle group. 2. ANB value showed the dignificant positive correlation to nasolabial, symphuseal, and interlabial angles and the significant negative felation to lower lip angle. 3. SN-GoMe vlue showed the significant positive correlation to mentolabial, symphyseal, nasofrontal, and upper lip angles. 4. Soft tissue profile contour in SK. Class II group showed greater accofdance to SN-GoMe value than those in SK. Class III group.
Lip

Over the past few decades, interest in minimally invasive spine surgery (MISS) has increased tremendously due to its core principle of minimizing approach-related injury while providing outcomes similar to traditional open spine procedures. With technical and technological advancements, MISS has expanded its utility not only to simple spinal stenosis, but also to complex spinal pathologies such as metastasis, trauma, or adult spinal deformity. In this article, we review the techniques and technology in MISS and discuss the indications, benefits, and limitations of MISS.

STUDY DESIGN: Thirty-seven patients with spinal tuberculosis were evaluated according to surgical method. OBJECTIVES: To evaluate the effectiveness of posterior spinal instrumentation in the surgical treatment of patient with tuberculous spondylitis. SUMMARY OF LITERATURE REVIEWS: There are many debates about the effectiveness of posterior spinal instrumentation combined with anterior interbody fusion in tuberculous spondylitis. MATERIALS AND METHODS: From January 1995 to June 2000, 37 patients were divided into two groups depending on their use of posterior spinal instrumentation. Group I consist of thirteen patients who were treated with conventional anterior corpectomy and anterior interbody fusion using autogenous strut bone graft. Group II was composed of twenty-four patients who were treated with conventional anterior corpectomy and anterior interbody fusion combined with posterior spinal instrumentation. Changes of corrected kyphotic angle and complication were measured using pre-, post-operative and follow-up radiographs and chart review. RESULTS: In group I, six cases (46.2%) showed loss of corrected kyphotic angle. Of these six cases, five cases had initial kyphotic angle of more than 20 dgree and three cases had involvement of two or more vertebrae. All six cases had thoracic or thoracolumbar involvement. Comparing two groups, maintaining corrected kyphotic angle and low complication rates were obtained in group II during follow-up period. The change of deformity as followed. In thoracic area, the mean kyphotic angle of 26.5 dgree was reduced to 18 dgree postoperatively, At the most recent follow-up, the mean kyphotic angle was 31.5 dgree in group I, a loss of correction of 13.5 dgree . In group II, the mean kyphotic angle was corrected from 27 dgrees to 13.5 dgree after surgery. At the most recent follow-up, the mean kyphotic angle was 17.5 dgrees, a loss of correction of 4 dgree . CONCLUSION: Posterior spinal instrumentation combined with conventional anterior corpectomy and anterior interbody fusion were found to be effective for preventing loss of kyphotic angle and for maintaining stable bone fusion in patients with mean
Congenital Abnormalities ; Follow-Up Studies ; Humans ; Spine ; Spondylitis* ; Transplants ; Tuberculosis, Spinal