1.CEA, CA19-9 and CA125 in patients with gastrointestinal carcinoma.
Hyung Tae KIM ; Soo Sang SOHN ; Jung Shin KANG
Journal of the Korean Cancer Association 1992;24(5):647-655
No abstract available.
Humans
2.Three Cases of Insulin Dependent Diabetes Mellitus in Children.
Tae Hoon LEE ; Sang Chul PARK ; Chang Hwi KIM ; Sang Man SHIN ; Sang Jhoo LEE
Journal of the Korean Pediatric Society 1983;26(3):285-289
No abstract available.
Child*
;
Diabetes Mellitus*
;
Humans
;
Insulin*
3.Treatment of intertrochanteric fracture with captured hip screw.
Sang Wook BAE ; Woo Ku JUNG ; Tae Hong KO ; Young Shin SHIN
The Journal of the Korean Orthopaedic Association 1993;28(6):2074-2082
No abstract available.
Hip*
4.In vitro 31P NMR spectroscopic assessment of the endurance and recovery capacity of skeletal muscle: comparison between the sedentaries and canoe athletes.
Tae Hawn LIM ; Tae Keun LEE ; Ki Hong SEONG ; Chi Woong MUN ; Sang Tae KIM ; Myung Jin SHIN
Journal of the Korean Radiological Society 1992;28(5):776-782
In vivo 31P NMR spectroscopic study of forearm wrist flexor muscles was performed in two groups of volunteers composed respectively of 6 sedentaries and 6 canoe athletes. A continuous isometric contraction of endurance exercises was adopted in oder to assess the endurance capacity and recovery potential of skeletal muscles. Differences in high energy phosphorus metabolism between the sedentaries and athletes were evaluated with and emphasis on the intracellular pH and Pi/PCr ratio as indicators of high energy phosphorus metabolism. There were no differences of baseline pH and Pi/PCr ratio between the two groups. The athletes sustained the exercise at more acidic intracellular pH and at a higher Pi/PCr ratio of intracellular conditions for an all-out than did the sedentaries. The recovery rate of pH showed no difference between the two groups. There was a tendency of faster recovery of Pi/PCr in athletes showing half recovery time(T1/2) of 39.0±3.0 seconds as compared to that of sedentaries (55.7±7.5 seconds). The recovery rate of Pi/PCr as a function of Pi/PCr ratio at a given period of time was significantly faster in athletes than in sedentaries (P<0.001). The correlation coefficient of the recovery rate of Pi/PCr against the Pi/PCr ratio was 0.985 and 0.914 respectively for the athletes and sedentaries. The pH and the Pi/PCR ratio at an all-out state can be used as indicators of endurance capacity and the recovery rate of Pi/PCr, as a reovery potential of skeletal muscles.
Athletes*
;
Exercise
;
Forearm
;
Humans
;
Hydrogen-Ion Concentration
;
In Vitro Techniques*
;
Isometric Contraction
;
Metabolism
;
Muscle, Skeletal*
;
Muscles
;
Phosphorus
;
Volunteers
;
Wrist
5.The Clinical Study on 28 Patients with the Pericardiac Effusion.
Tae Sung KIM ; Sang Kee LEE ; Kee Young SHIN ; Woo Kun CHOI ; Jong Seong KIM
Korean Circulation Journal 1981;11(2):11-22
The clinical study was performed to 28 patients with the pericardiac effusion who were admitted in Busan university Hospital and Paik Hospital, In-Je Medical College, Busan, korea during March 1976 and July 1981. The results were as following; 1) 12 cases(42.9%) of total 28 pericardiac effusion occured in 3rd decade, 8(28.5%) in 2nd decade and 5 cases(17.9%) in 4th decade. Sex distribution showed male to female 2.5:1. 2) With etiological distribution there were 15 cases(53.6%) tuberculous, 5(17.9%) nonspecific, 3(10.7%) malignant, 2(7.1%) pyogenic, 2 traumatic and 1(3.6%) rheumatic. 3) On admission 28 cases(100%) complained of dyspnea, 24(85.7%) distant heart sound, 20(71.4%) each engorged jugular vein and edema, 18(64.3%) each cough and abdominal fullness, 17(60.7%) each sputum and chest discomfort and pain, 12(42.9%) fever, 11(39.1%) orthopnea, 10(35.7%) chilling, 7(25%) oliguria, 4(14.6%) palpitation and 3(17.2%) headache. Increased cardiac dullness was observed in 26 cases(71.4%), hepatomegaly 18(64.3%), pulmonary rales 17(60.7%), ascites 13(46.1%), fever 12(42.9%), pericardiac friction rub 10(35.7%), splenomegaly 7(25%), paradoxical pulse 6(21.4%) and jaundice 2(7.1%). 4) On amission SGOT and SGPT level was increased each in 15(53.6%) and 13(46.7%), TTT and CCF abnormal in 10(35.7%), and 8(28.5%), serum NPN, BUN, creatinine increased in each 10(35.7%), 11(39.1%), 8(28.5%), WBC increased in 6(21.4%), RBC decreased in 8(28.5%) and ESR increased in 16(57.1%). 5) Characteristics of pericardiac effusion showed hemorrhagic 17(60.7%), serosangeous 6(21.4%), sangeous 3(17.2%) and pyogenic 2 cases(7.1%). 6) The ECG on admission revealed low voltage in 25(89.1%), depressed ST segment in 13(46.1%) and inverted T wave in 12(42.9%). 7) Chest X-ray showing cardiomegaly 28(100%), pleural effusion in 20(71.4%), and pulmonary congestion in 16(57.1%). 8) The m mode and 2-D Echocardiogram showed echo free space in 28 cases and after pericardiocentesis the space was reduced or disappeared. 9) 19 cases of 28(67.5%) were improved clinically, while 5 cases(17.9%) were not improved and 4 cases(14.6%) died.
Alanine Transaminase
;
Ascites
;
Aspartate Aminotransferases
;
Busan
;
Cardiomegaly
;
Cough
;
Creatinine
;
Dyspnea
;
Edema
;
Electrocardiography
;
Estrogens, Conjugated (USP)
;
Female
;
Fever
;
Friction
;
Headache
;
Heart Sounds
;
Hepatomegaly
;
Humans
;
Jaundice
;
Jugular Veins
;
Korea
;
Male
;
Oliguria
;
Pericardiocentesis
;
Pleural Effusion
;
Respiratory Sounds
;
Sex Distribution
;
Splenomegaly
;
Sputum
;
Thorax
6.A Case of Metastatic Tuberculous Abscess of Skin Following Intestinal Tuberculosis.
Tae Hyung KIM ; Jang Oh KIM ; Ho Cheol SHIN ; Sang Won KIM
Korean Journal of Dermatology 1995;33(3):510-515
We reported herein a rare case of a 65-year-old female who lead intestinal tuberculosis of about 2 months duration, with little late development of metastatit berculosis abscess of the skin. The lesions were egg tow wolnut-sized abscesses or nodules occu in, on the back, right flank and lower abdomen with no pain or mild tenderness. Physical exami saion was unremarkable on dissemination of other sites. The tuberculin test was negative. The skin esions were diagnosed by clinical, histopathologic features, and positive results for Mycobactc iuntuberculosis in smear.; and cultures in the pus discharge: as well as polymerase chain reaction nethod on the nodular lesion. A barium enema showed the findings of intestinal tuberculosis, with positive culture in the stool. A combined treatment was intituted. During the initial 4 month, utaneous lesions did not respond and in some cases worsened with the multidrug of isoniazicr fampin, pyrazinamide and streptomycin, all of which were surgically excised. Thereafter, the drugs of isoniazid and rifampin were further administered for ahout 14 months, with the complete resecution of both lesions and the systemic symptomatolo. There was no relapse at follow-up after 6 months.
Abdomen
;
Abscess*
;
Aged
;
Barium
;
Enema
;
Female
;
Follow-Up Studies
;
Humans
;
Isoniazid
;
Ovum
;
Polymerase Chain Reaction
;
Pyrazinamide
;
Recurrence
;
Rifampin
;
Skin*
;
Streptomycin
;
Suppuration
;
Tuberculin Test
;
Tuberculosis*
7.Phospholipase A2 Contributes to Hemorrhage-induced Acute Lung Injury Through Neutrophilic Respiratory Burst.
Yoo Suck JANG ; Seong Eun KIM ; Sang Hoon JHEON ; Tae Rim SHIN ; Young Man LEE
Tuberculosis and Respiratory Diseases 2001;51(6):503-516
BACKGROUND: The present study was carried out in association with neutrophilic respiratory burst in the lung in order to clarify the pathogenesis of acute respiratory distress syndrome(ARDS) following acute severe hemorrhage. Because oxidative stress has been suggested as one of the principal factors causing tissue injury, the role of free radicals from neutrophils was assessed in acute hemorrhage-induced lung injury. METHOD: In Sprague-Dawley rats, hemorrhagic shock was induced by withdrawing blood(20 ml/kg of B.W) for 5 min and the hypotensive state was sustained for 60 min. To determine the mechanism and role of oxidative stress associated with phospholipase A2(PLA2) by neutrophils, the level of lung leakage, pulmonary myeloperoxidase(MPO), and the pulmonary PLA2 were measured. In addition, the production of free radicals was assessed in isolated neutrophils by cytochemical electron microscopy in the lung. RESULTS: In hypotensive shock-induced acute lung injury, the pulmonary MPO, the level of lung leakage and the production of free radicals were higher. The inhibition of PLA2 with mepacrine decreased the pulmonary MPO, level of lung leakage and the production of free radicals from neutrophils. CONCLUSION: A. neutrophilic respiratory burst is responsible for the oxidative stress causing acute lung injury followed by acute, severe hemorrhage. PLA2 activation is the principal cause of this oxidative stress.
Acute Lung Injury*
;
Free Radicals
;
Hemorrhage
;
Lung
;
Lung Injury
;
Microscopy, Electron
;
Neutrophils*
;
Oxidative Stress
;
Phospholipases A2*
;
Phospholipases*
;
Quinacrine
;
Rats, Sprague-Dawley
;
Respiratory Burst*
;
Shock, Hemorrhagic
8.A case of Lipoleiomyoma of the Uterus.
Hea Su SHIN ; Sung Min SON ; Young Min YANG ; Tae Sang KIM ; Ik Su KIM
Korean Journal of Obstetrics and Gynecology 2000;43(10):1853-1856
No abstract available.
Uterus*
9.DNA ploidy and Cellular Proliferation Activity in Experimentally Induced Malignant Fibrous Histiocytoma.
Ji Shin LEE ; Jong Tae PARK ; Sang Woo JUHNG ; Hong Ran CHOI ; Kyu Hyuk CHO
Korean Journal of Pathology 1993;27(3):205-216
To fine out the changes of DNA ploidy and cellular proliferation activity during carcinogenesis and evaluate correlation between flow cytometrically determined S-phase fraction and proportion of proliferation cell nuclear antigen(PCNA, PC10) immunoreactive cells, the authors studied on malignant fibrous histocytoma induced by intra-articular injection of 9, 10-dimethy1-1, 2-benzanthracene(DMBA) in the rats. Forty Wistar rats were used. The results obtained were as follows. 1) Firstly, tumors were palpated 5 weeks after the last injection of DMBA and formed in 27 rats at sacrificed. Histologically, these lesions showed storiform, indicative of malignant fibrous histiocytoma. 2) Three cases of DNA aneuploidy were observed at 4 and 5 months after the last injection of DBMA and one of them, which was DNA diploidy at main mass, was found at daughter mass. 3) Flow cytometrically determined S-phase fraction and proportion of PCNA(PC10) immunoreactive cells in malignant fibrous histiocytoma induced by DMBA were much higher than in control groups and slightly increased according to sequential changes after formation of mass. The comparison of flow cytometrically determined S-phase fraction and proportion of PCNA(PC10) immunoreactive cells showed significant correlation(r=0.6092, p<0.001). Above results strongly suggest that ploidy pattern may evolve into aneuploid type during the development of tumor and proliferation activity increases during the carcinogenesis.
Rats
;
Animals
10.A clinical study with pirarubicin in the advanced breast cancer.
Seung Taek OH ; Sang Sul JUNG ; Jong Tae SHIN ; In Chul KIM ; Eui Dong KIM
Journal of the Korean Cancer Association 1993;25(6):935-940
No abstract available.
Breast Neoplasms*
;
Breast*