Lymphomatoid papulosis is an enigmatic disease entity which is clinically benign and histologically malignant. Although sporadic cases have been reported, we could not find any comprehensive report on the combined clinical and histologic features of lymphomatoid papulosis in the literature. Perhaps the most controversial aspect of lymphomatoid papulosis is its pathogenesis and categorization as a benign versus a malignant entity. To date, there are no reports on p53 and bcl-2 protein expression in lymphomatoid papulosis. We analysed the clinico-pathological findings of 18 cases with lymphomatoid papulosis during the 10 year period from 1984 to 1995 and examined the prevalence of immunoreactivity for CD30(DAKO, Ber-H2), p53(DAKO, DO-7), and bcl-2(DAKO, 124) using an immunohistochemical(ABC) method. The results obtained are summarized as follows. 1) Age distribution ranged from 20 to 65, with a mean age of 45 years and a sex distribution which showed a male predominence(8:1). The lesions were located on the trunk and extremities(8cases), extremities (7cases), and trunk(3 cases). The morphology of the lesions were papules or plaques(12 cases), and nodules(6 cases). 2) Histopathologic types were classified into 3 types: type A(4 cases), type B(8 cases) and mixed type (6 cases). 3) Positive immunoreactivity for CD30 was seen in 17%(3 of 18cases): type A(2 of 3) and mixed type(1 of 3). 4) The positive immunoreactivity for p53 and bcl-2 was observed in 29%(5 of 18) and 11%(2 of 18), respectively. 5) Cases showing positive immunoreactivity for P53 were type A(1 of 5), type B(1 of 5), and mixed type(3 of 5). 6) Cases showing positive immunoreactivity for bcl-2 were mixed type(2 of 2). One case developed into Ki-1 lymphoma. These results support the idea that lymphomatoid papulosis and Ki-1 lymphoma represent a continuum. The role of p53 gene mutation and bcl-2 activation in the development of lymphomatoid papulosis is currently unknown. But, our results suggest that p53 gene mutation and bcl-2 activation are not a critical step in the development of lymphomatoid papulosis. Further studies are needed to elucidate the role of p53 gene mutation and bcl-2 activation in the development and progression of lymphomatoid papulosis.
Male ; Humans ; Genes, p53

Differential diagnosis between tuberculous epididymitis and nonspecific chronic epididymitis is one of the most difficult problem in the field of urology. The definitive diagnosis of tuberculous epididymitis is often made by pathological examination of the epididymectomy or orchiectomy specimen. However, the preferred approach to treatment of tuberculous epididymitis is primarily antituberculous chemotherapy and we believe that as a primary measure, surgical procedure is avoidable with careful clinical work-up. A clinical comparative investigation was undertaken on 20 cases of tuberculous epididymitis and 13 cases of nonspecific chronic epididymitis, diagnosed by histopathologic examination during recent 6 year period. Tuberculous epididymitis occurred most frequently in men aged 21-30 years (80%), whereas nonspecific chronic epididymitis occurred frequently in men aged above 31 years (69.2%). Tuberculous epididymitis and nonspecific chronic epididymitis Were present clinically as painless scrotal mass in 70%, 53.8%, painful scrotal mass in 30%, 46.2%, and voiding symptoms in 15%, 7.7% respectively. Scrotal swelling were present in 30% of tuberculous epididymitis, but only in 7.7% of nonspecific epididymitis. Irregularity of mass were noted in 65% of tuberculous epididymitis, and in 23.1% of nonspecific epididymitis. Scrotal fistula were present only in 5% of tuberculous epididymitis. Of the patients with tuberculous epididymitis, 20% had a history of tuberculosis, and 46.1% of the patients with nonspecific chronic epididymitis had a history of acute epididymitis. In tuberculous epididymitis, clinical findings of concurrent infection with tuberculosis were found in kidney, prostate, vas, lung, and testis in order of frequency. Past history of tuberculosis or acute epididymitis and clinical findings of concurrent tuberculous lesions were helpful for clinical diagnosis, in 70% of the patients with tuberculous epididymitis and 46.2 % of the patients with nonspecific chronic epididymitis.
Diagnosis ; Diagnosis, Differential ; Drug Therapy ; Epididymitis* ; Fistula ; Humans ; Kidney ; Lung ; Male ; Orchiectomy ; Prostate ; Testis ; Tuberculosis ; Urology

We report a case of Becker's nevus associated with ipsilateral breast hypoplasia in a 13-year-old female. Three years esrlier, she noticed a palrn-size hyperpigmented area on her left chest. The lesion showed a well defined geographic border. No hypertrichosis was seen. Hypoplasia was apparent on the left breast. A histopathologic finding showed a slightly hyperpigmented epidermis and some rectangular rete ridges with flat bases.
Adolescent ; Breast* ; Epidermis ; Female ; Humans ; Hypertrichosis ; Nevus* ; Thorax

No abstract available.
Anterior Temporal Lobectomy* ; Seizures*

Pneumomediastinum is a relatively uncommon, infrequently reported entity, In the evaluation of these entity, it is important to exclude pathological causes, including Boerhaave's syndrome which carries a high mortality. Spontaneous pneumomediastinum is related to excessive intraalveolar pressure leading to rupture of perivascular alveoli in the setting of a Valsalva maneuver without communication to gut material. So, it has a benign self-limited course and rarely requires medical intervention. On the contrary, secondary pneumomediastinum caused by instrumental, traumatic, and spontaneous perforation of esophagus. Although the prognosis have been improved since the advent of broad-spectrum antibiotics and nutritional support, pneumomediastinum due to esophageal perforation still has a high morbidity and mortality. The most important prognostic factor is the time interval between perforation and initiation of therapy, and an awareness and a high clinical suspicion is critical in the early diagnosis and treatment. Recently, we have experienced 2 cases of pneumomediastinum, one case was spontaneous pneumomediastinum and the other may be caused by instrumental esophageal perforation. We report the clinical course of the patients with a current literature review.
Anti-Bacterial Agents ; Early Diagnosis ; Esophageal Perforation ; Esophagus ; Fibrinogen ; Humans ; Mediastinal Emphysema* ; Mortality ; Nutritional Support ; Prognosis ; Rupture ; Valsalva Maneuver

No abstract available.
Hip*

No abstract available.
Action Potentials* ; Adult* ; Humans ; Median Nerve* ; Ulnar Nerve*

Dislocation involving talus is a rare injury comprising less than 1% of all dislocations of the joint. One case of lateral subtalar di location of the talus treated at the Department of Orthopedic Surgery, Kang Nam General Hospital in Decernber 1985. The patient was followed for 6 months and satisfactory healing was obtained.
Dislocations ; Hospitals, General ; Humans ; Joints ; Orthopedics ; Talus

In Korea, slipped capital femoral epiphysis is a rare disease. In which the capital femoral epiphysis migrate posteriorly and inferiorly against the neck portion. Sometimes it should be differentiated from other conditions that separate the femoral capital epiphysis. We have experienced a rare case of separation of capital femoral epiphysis due to an osteosarcoma in the proximal femoral metaphysis in the 15 years of old girl.
Epiphyses ; Female ; Humans ; Korea ; Neck ; Osteosarcoma ; Rare Diseases ; Slipped Capital Femoral Epiphyses

Hypochondroplasia is a form of short
Achondroplasia ; Christianity ; Dwarfism ; Extremities ; Hand