2.Direct Immunofluorescent Studies in the Scabies.
Korean Journal of Dermatology 1984;22(4):381-386
There are many reports about the deposition of immunoglobulins and complement by direct immunofluorescence(DIF) in the lesion of scabies. The authors investigated the immunoglobulins and C, for the purpose of studying the immunologic reactivity of the host to scabies mites by DIF. The results are summerized as follows: Total number of the cases investigated were 20 (18 males, 2 females), of whom 11 were in their third decade of age. The clinical forms of the tested lesions were papular type (7 cases), nodular type (12 cases), and Norwegian type (1 case). The durations of the patients were mostly within 2 months, but was 9 months in 1 case of nodular type, Deposition of immunoglobulin and C, was demonstrated by DIF in 10 of 12 cases (83. 3%) of nodular type, and 1 of 7 cases (14. 3%) of papular type. The Norwegian type showed negative results. There seemed to be no relation between the duration of scabies and positive rates. Of 20 cases tested, immunoglobulin and C, were deposited in the vascular wall in 11 lesions (55%), and at the dermoepidermal junction in 3 lesions (15%). While in 1 of 7 cases of papular type both IgM and C, were observed, IgM and C, were noted in 7 and 9, respectively, in 12 cases of nodular type.
Complement System Proteins
;
Humans
;
Immunoglobulin M
;
Immunoglobulins
;
Male
;
Mites
;
Scabies*
3.A Case of Kaposi's Varicelliform Eruption Occuring in Pemphigus Foliaceus.
Su Hee OH ; Jong Seok HWANG ; Sang Lip CHUNG
Korean Journal of Dermatology 1984;22(6):635-638
This report presents a case of a 17-year-old-girl who developed a, Kaposis varicelliforrn eruption(eczema herpeticum) during oral prednisolone therapy in order to control pemphigus foliaceus. Diagnosis was made by the history, clinical feature and histologic examination. Within 24 hours after the initiation of therapy with ribavirin(Viramid), new lesions had ceased to develop.
Diagnosis
;
Kaposi Varicelliform Eruption*
;
Pemphigus*
;
Prednisolone
4.Distribution of Causative Fungi in Home Environment of Parients with Tinea Capitis Caused bu Microsporum Canis.
Su Hee OH ; Soon Bong SUH ; Sang Lip CHUNG
Korean Journal of Dermatology 1990;28(2):165-173
Isolation of Microsporum canis from home environment was carried out for 30 tinea capitis patients infected by M, canis. M. canis was isolated in 84.2-100% of patients caps, mattresses, clothes and pillows and families' clothes. The greatest mean number of M. canis colonies per petri dish was found in the patients pillows and followed by caps, mattresses, outerwear, and underwear. Mean number of M. canis colonies in the clothes of mothers, grandmothers, brothers, sisters and roommates of patients was smaller than that of the M. canis colonies in the clothes of patients but greater than that isolated from the clothes of other family members. Frequency of isolation and mean number of colonies decreased drarnatically after 2 weeks therapy and rarely isolated after 6 weeks therapy. M. canis was isolated in 100% of the house dust of patients. Isolation index was greater in the house dust of patients with concomittant infection of other family members and with lesions of scaly and inflammatory type. M. canis was isolated from cats and goat of patients by the hair brush technique.
Animals
;
Beds
;
Cats
;
Dust
;
Fungi*
;
Goats
;
Hair
;
Humans
;
Microsporum*
;
Mothers
;
Siblings
;
Tinea Capitis*
;
Tinea*
5.A Case of Sea Urchin Granuloma.
Do Won KIM ; Su Hee OH ; Sang Lip CHUNG
Korean Journal of Dermatology 1983;21(4):445-449
Sea urchin granuloma is a rare skin disorder, considered to be allergic or foreign body reaction caused by stick of spines of sea urchin. However, detection of the spine in the granuloma is quite difficult. A 27 year-old marine was seen with several asymptomatic hard nodules on the dorsum of hands, fingers, forearrns and knees at the injured site of the spines after a latent period of 6 rnonths. Histolagical examination revealed dermal granulomatous inflamation with hyperkeratotic and acanthotic epidermis. On examination with polarized microscopy, sea urchin spines in the granuloma were seen as bright white fragments in the dark field. Those nodules were regressed with intralesional injection of triamcinoIone.
Adult
;
Epidermis
;
Fingers
;
Foreign-Body Reaction
;
Granuloma*
;
Hand
;
Humans
;
Injections, Intralesional
;
Knee
;
Microscopy
;
Sea Urchins*
;
Skin
;
Spine
6.Expression of bcl-2 and p53 Protein, and Apoptosis in Transitional Cell Carcinoma of the Bladder.
Myoung Ja CHUNG ; Sang Su KIM ; Ho Yeul CHOI
Korean Journal of Pathology 2000;34(8):567-573
This study examined the expression of the bcl-2 protein in 59 cases of transitional cell carcinomas (TCCs) of the bladder and evaluated the relationship of bcl-2 and p53 with apoptosis. The cases were divided into 41 low-grade TCCs, 18 high-grade TCCs, 32 superficial TCCs, and 27 invasive TCCs. p53 and bcl-2 protein were detected by the immunohistochemical method and apoptosis was analysed by using hematoxylin-eosin stained slide. The results were as follows: bcl-2 protein was detected in 8 (14%) TCCs and all of these cases were low grade TCCs. Expression of bcl-2 protein was not correlated with clinical stage. There was no correlation between bcl-2 and p53 protein. According to the immunohistochemical results of bcl-2 and p53 protein, the cases were divided 4 groups. Apoptotic index (AI) was higher in p53 positive/ bcl-2 negative group than other groups but the significance was recognized only between p53 positive/bcl-2 negative group and p53 negative/bcl-2 negative group (p<0.05). p53 protein was detected in 20 (36%) TCCs and its expression was correlated positively with histologic grade and clinical stage (p<0.05). AI correlated positively with histologic grade and clinical stage (p<0.01). These data indicate that overexpression of bcl-2 protein is rare in TCC of the bladder and associated with low grade TCCs. Overexpression of p53 is associated with the tumor progression in the TCCs. AI correlates with p53 positivity but does not correlate with bcl-2 positivity.
Apoptosis*
;
Carcinoma, Transitional Cell*
;
Urinary Bladder*
7.A case of miller fisher syndrome.
Sang Deug CHUNG ; Kyung Ok KO ; Keon Su RHEE ; Yong Hun CHUNG
Journal of the Korean Child Neurology Society 1993;1(1):158-164
No abstract available.
Miller Fisher Syndrome*
8.Effect of Intrathecal Neostigmine on Post-Cesarean Section Analgesia.
Sang Seon CHO ; Ji Su KIM ; Chan Jong CHUNG ; In Suk HAN ; Sa Chung JANG
Korean Journal of Anesthesiology 1998;35(3):545-552
BACKGROUND: Intrathecal (IT) neostigmine produces analgesia in animal and human. This study was designed to evaluate the efficacy and safety of IT neostigmine for post-cesarean section analgesia. METHODS: Forty-five women undergoing cesarean section under spinal anesthesia were randomly assigned into 3 groups to receive; normal saline 0.2 ml, or neostigmine 12.5 microgram, or neostigmine 25 microgram intrathecally with 0.5% hyperbaric bupivacaine 12 mg. Degrees of sensory and motor blocks, maternal hemodynamic changes, and side effects were recorded. Apgar scores and umbilical vein blood gas analysis (UVBGA) were checked for evaluation of fetal status. Postoperative analgesia was provided by intravenous patient-controlled analgesia (PCA) using fentanyl 500 microgram and ketorolac 150 mg in 100 ml. Pain scores with 10-cm visual analogue scale (VAS), time to first PCA use, cumulative PCA consumptions, and side effects were assessed at 1, 2, 4, 8, 12, 24, and 48 hr after IT injection. RESULTS: There were no significant differences among the three groups in characteristics of spinal anesthesia, maternal blood pressure and heart rate, Apgar scores, and UVBGA data. Compared to saline group, IT neostigmine significantly prolonged time to first PCA use and decreased 24 hr- and 48 hr-PCA consumptions (P<0.05). Pain scores in neostigmine groups were significantly lower than those in saline group for first 4 hr after which there were no differences among the three groups. There were significantly higher incidences of nausea and vomiting in neostigmine groups than in saline group. CONCLUSIONS: These data indicate that IT neostigmine can be an alternative postoperative analgesic without adverse fetal effects for cesarean section. However, high incidence of nausea and vomiting seem to limit its clinical usefulness. Further studies are necessary to enhance its analgesic effects and to decrease its adverse effects.
Analgesia*
;
Analgesia, Patient-Controlled
;
Anesthesia, Spinal
;
Animals
;
Blood Gas Analysis
;
Blood Pressure
;
Bupivacaine
;
Cesarean Section
;
Female
;
Fentanyl
;
Heart Rate
;
Hemodynamics
;
Humans
;
Incidence
;
Ketorolac
;
Nausea
;
Neostigmine*
;
Passive Cutaneous Anaphylaxis
;
Pregnancy
;
Umbilical Veins
;
Vomiting
9.The Effect and Retention of CPR Training in Nursing Students.
Su Hong KIM ; Sang Hee KIM ; Chung Sin SHIM
Journal of the Korean Society of Emergency Medicine 2007;18(6):496-502
PURPOSE: This study was done to evaluate the effect and retention of CPR training in nursing students. METHODS: The participants were 64 nursing students enrolled in K University in Busan. Data were collected from April 3 to October 20, 2006 using a structured questionnaire. Data were analyzed using the SPSS/PC 12.0 statistical program. RESULTS: The first hypothesis, that knowledge (t=-17.865, p=0.000) and skill (t=-11.216, p= 0.000) scored directly following the teaching program would be higher than before the program, was supported. The second hypothesis, that knowledge (t=-8.325, p=0.171) and skill (t=-9.812, p=0.062) scored directly after the teaching program would be higher than two months later, was rejected. The third hypothesis, that knowledge (t=-9.162, p=0.010) and skill (t=-6.019, p=0.023) scored two months after the program would be higher than four months after the program, was supported. The last hypothesis, that knowledge (t=9.169, p=0.210) and skill (t=-5.012, p=0.319) scored four months after the program would be higher than six months after the program, was rejected. CONCLUSION: Overall retention of CPR training among nursing students, without reinforcement, decreases most significantly between two and four months following initial training. Accordingly CPR training should be repeated with the same clients every four months.
Busan
;
Cardiopulmonary Resuscitation*
;
Education
;
Humans
;
Nursing*
;
Surveys and Questionnaires
;
Students, Nursing*
10.A Case of Pulmonary Carcinosarcoma which Metastasize to Pelvic Cavity After Left Pneumonectomy.
In Su JUNG ; Young Jee KIM ; Chung Hyeon KIM ; Si Min KIM ; Sang Moo LEE ; Youngsoo AHN
Tuberculosis and Respiratory Diseases 2001;51(5):453-461
Pulmonary carcinosarcoma(Sarcomatoid carcinoma of the lung) is a rare pulmonary malignancy, which is defined as having an admixtture of both carcinomatous and sarcomatous components. Pulmonary carcinosarcoma occurs most frequentlly in males between 50 and 80 years of age. It predominantly affects the upper lobe and/or the principal bronchi, and is associated with a history of smoking. Here, we report a case of pulmonary carcinosarcoma with a left lobe atelectasis due to an endobronchial mass in a 56-year-old male. After a left pneumonectomy, the pathologic stage was IIb (T3N0M0). Four months later, an abdominal mass was observed and exploratory laparotomy revealed metastases of the pulmonary carcinosarcoma to the pelvic cavity.
Bronchi
;
Carcinosarcoma*
;
Humans
;
Laparotomy
;
Male
;
Middle Aged
;
Neoplasm Metastasis
;
Pneumonectomy*
;
Pulmonary Atelectasis
;
Smoke
;
Smoking