1.The Effect of Electrical Stimulation on Bone: An Experimental Study on Rabbits
In Suk OH ; Duk Yong LEE ; Moon Sang CHUNG ; Soo Yong LEE ; Sang Bin OH
The Journal of the Korean Orthopaedic Association 1982;17(5):1047-1054
Experiences of 26 cases of electrical bone stimulation on normal adult rabbits was documented in this paper. The cathodic electrode was introduced longitudinally into the medullary cavity of the proximal tibia and the anodic electrode was introduced transversely in the distal femur of the same side. The contralateral tibia was used as the control, of which the Teflon coated Kirschner wire was introduced longitudinally into the medullary cavity. 10uA of direct current was passed continuously through the fixed wires between the proximal tibia and distal femur. At the second, fourth and sixth week, random bone scan with 99m-Tc was performed and the animals were sacrificed. The specimen X-rays of the tibia and femur were taken and the specimens were prepared for the microscopic study. The followings are obtained from this experimental study. 1. The rate of new bone formation is 69.2% in the stimulated group and 7.7% in the control group. There were also fibrosis and cartilage formation as well as the new bone formation. The fibrosis and cartrilage formation are observed only in the electrically stimulated side and their occurances are 69.2% and 11.1% respectively. So The new bone formation and fibrosis are definitely increased in the bones of the cathodic electrical stimulation than those of the control side. 2. The intramembraneous ossification is the predominent feature of this electrically stimulated new bone formation. 3. Bone and soft tissue necrosis was the main microscopic feature in the anode side. 4. Since new bone, fibrous tissue and sometimes new cartilage were observed in this study, it seems that the cathodic electrical stimulation is not specific for the new bone formation, but induce crude tissues such as bone, cartilage, fibrous tissue or vessels. Furthermore, it can be postulated that the 10uA electrical stimulation is only one of the best electrical environment for the formation of the crude tissues, especially for bone and fibrous tissue.
Adult
;
Animals
;
Cartilage
;
Electric Stimulation
;
Electrodes
;
Femur
;
Fibrosis
;
Humans
;
Necrosis
;
Osteogenesis
;
Polytetrafluoroethylene
;
Rabbits
;
Tibia
2.Epidemiological studies on familial aggregation of selected cancers.
Jhin Oh LEE ; Soo Yong CHOI ; Yun Sang SHIM
Journal of the Korean Cancer Association 1991;23(3):658-666
No abstract available.
Epidemiologic Studies*
3.A study of serologically confirmed measles.
Sang Mook CHOI ; Chang Soo OH ; Sang Chul PARK ; Chang Hwi KIM ; Sang Jhoo LEE
Journal of the Korean Pediatric Society 1992;35(4):508-514
No abstract available.
Measles*
4.A case of Prune Belly syndrome associated with Turner syndrome.
Chang Soo OH ; Sang Muk CHOI ; Jae Ock PARK ; Chang Hwi KIM ; Sang Jhoo LEE
Journal of the Korean Pediatric Society 1992;35(7):978-983
No abstract available.
Prune Belly Syndrome*
;
Turner Syndrome*
5.Objective measurenment with stabilometry of dizzy symptoms(1): Based on stabilometry.
Sang Cheol LEE ; Bong Whan OH ; Seong Soo KIM ; Sang Mok LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(4):612-623
No abstract available.
6.Results of Limb Salvage Surgery in Primary Malignant Bone Tumors
Han Koo LEE ; Sang Hoon LEE ; Han Soo KIM ; Sang Min LEE ; Joo Han OH
The Journal of the Korean Orthopaedic Association 1996;31(3):569-580
Limb salvage operation in primary malignant bone tumors is increasing recently, according to the improvement of diagnostic methods, surgical technique and adjuvant chemotherapy. The purpose of this study is to obtain the interim results of survival rate and the functional grade of the limb in primary malignant bone tumors treated by limb salvage operation. Between 1985 to 1993, 63 primary malignant bone tumors treated by limb salvage operations. Tumor prosthesis arthroplasty was performed in 49 patients, resection arthrodesis in 9 patients, and IM nailing with cement molding in 5 patients. Autoclave autograft was combined in 2 patients. Adjuvant chemotherapy and postoperative radiotherapy were performed in selected patients. The average follow-up period was 50 months(ranged 12 months to 116 months). In the cases of osteosarcoma, estimated survival rate was 61.9% based on Kaplan-Meier survival plot. In the parosteal sarcoma, the survival rate was 87.5% and 80% in chondrosarcoma patients. According to functional grading by Enneking, 66% was excellent, 20% was good, 11% was fair and one patients was poor. Complications occurred in 16 patients:wound infection was developed in 6 patients, local recurrence in 4, peroneal nerve palsy in 2 patients and femoral stem loosening in 2 patients. Fracture in resection arthrodesis and pulmonary metastasis were also occurred. Reoperation was performed in 10 patients at average 31 months after initial operation. Revision tumor persthesis arthroplasty was performed in one patient due to local recurrence and in 2 patients due to femoral stem loosening. Three amputations were done due to recurrence of tumor. IM nailing with cement molding was performed in one patient due to deep infection and repeated arthrodesis was done in a fracture patients. Scheduled custom-made tumor prosthesis arthroplasty was performed within a year in 2 patients treated with IM nailing with cement molding. In conclusion, with the careful preoperative assessment, adjuvant chemotherapy and skillful surgical technique, limb salvage operation would provide the primary malignant bone tumor patients for longer survival and better quality of life.
Amputation
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Arthrodesis
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Arthroplasty
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Autografts
;
Chemotherapy, Adjuvant
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Chondrosarcoma
;
Extremities
;
Follow-Up Studies
;
Fungi
;
Humans
;
Limb Salvage
;
Neoplasm Metastasis
;
Osteosarcoma
;
Paralysis
;
Peroneal Nerve
;
Prostheses and Implants
;
Quality of Life
;
Radiotherapy
;
Recurrence
;
Reoperation
;
Sarcoma
;
Survival Rate
7.A case of neonatal hydrometrocolpos causing urinary obstruction.
Chang Soo OH ; Myung Lye KIM ; Byung Tae KIM ; Sang Jhoo LEE ; Soo Hyoung SEO
Journal of the Korean Pediatric Society 1992;35(11):1597-1601
No abstract available.
8.A Study on Plasma Levels of Testosterone and Dehydroepiandrosterone - sulfate ( DHEA - S ) in the Patients with Acne Vulgaris.
Nack In KIM ; Hee Soo OH ; Sang Soo LEE ; Moo Hyung LEE ; Choong Rim HAW
Korean Journal of Dermatology 1989;27(1):29-33
This study was performed to detect the hormonal abnormalities and to investigate the relationship between the levels of plasma testosterone and DHEA-S in 21 female patients with acne vulgaris using radioimmunoassay. The results were as follows : 1. The levels of plasma testosterone in patients group and control group(n=9) were 352+/-11.8 ng/dl, 223+/-9.7 ng/dl, respectively, and significantly elevated in patient group(p < 0.01), 2. The levels of plasma DHEA-S in patient group and control group were 286.6+/-126.8 pg/dl, 238.6+/-60.0 pg/dl, respectively, and did not show statistical significance. 3. The levels of plasma testosterones in patient subgroups classified by modified Pillsbury method were as follows minor group 32.6+5.3 ng/dl, mild group 33.4+/-15,5 ng/dl, moderate group 39.6+/-12.6 ng/dl. The testosterone levels in all the subgroups increased significantly than those in control group(352-t11.8 ng/dl) (p<0.05, p<0.05 p < 0.01) 4. The levels of plasrna DHEA-S in patient subgroups were follows minor group 242.5+/-412 pg/dl, mild group 263.9+/-166.1 pg/dl, moderate group 353.4+/-1273 pg/dl. The DE3EA-S levels in moderate group increased significantly than those in cotrol (238,6+/-60,0 pg/dl) and minor group(p<0.05). 5. There was no correlation between the plasma testosterone levels and the plasma DHEA-S levels in the acne patients.
Acne Vulgaris*
;
Dehydroepiandrosterone*
;
Female
;
Humans
;
Plasma*
;
Radioimmunoassay
;
Testosterone*
9.A Case of Cutaneous Sinus Tract of Dental Origin.
Soo Hong KIM ; Sang Jin PARK ; Jeong Joon OH ; Eil Soo LEE
Annals of Dermatology 2002;14(4):235-238
The most common cause of chronic draining sinus tract on the face and neck is the extension of chronic dental infection. The presence of an intermittently draining granulomatous lesion on the face or neck should alert clinicians to the necessity of routine dental examination including radiographic studies. Early correct diagnosis and appropriate dental treatment can pre-vent unnecessary and ineffective antibiotic therapy or surgical treatment. We report a case of a 22-year-old woman with a cutaneous sinus tract on submental region, associated with a periapical abscess of the left mandibular lateral incisor.
Cutaneous Fistula
;
Diagnosis
;
Female
;
Humans
;
Incisor
;
Neck
;
Periapical Abscess
;
Young Adult
10.A Clinical Review of the HELLP Syndrome.
Sang Tae AHN ; Haeng Soo KIM ; Jeong In YANG ; Joon Hwan OH ; Ki Su HAN ; Seong Cheon YANG ; Kie Suk OH
Korean Journal of Perinatology 2001;12(2):122-130
No abstract available.
Female
;
HELLP Syndrome*
;
Pregnancy