Sixty-six cases of erythena nodosum(EN) and erythema induraturn(EI) were examined pathologically and clinically. Pathologically 23 cases were erythema nodosum, 43 cases were erytherna induratum. Pathological diagnosis made without any prior knowledge of the clinical and laboratory data. Clinical manifestations were reviewed on basis of pathological diagnosis. The results are as follows; l. EN and EI mainly occurred in female, age of twenties and during spring season. There was no difference in sex, age and seasonal incidence between EN and EI. 2. Both EN and EI affected chiefly the shins. EI was more common than EN in cases of calf involvement. 3. Tenderness and systemic symptoms developed more often in EN, while ulcers occurred only in EI. 4 EI had relatively long duration. There was no difference in the recurrence rate between EN and EI. 5. Pulmonary tuberculosis was found only in El on chest X-rays. 6. Clinical and pathological diagnosis was identical in almost cases of EN but those were variable in case of EI.
Diagnosis ; Erythema Induratum* ; Erythema Nodosum* ; Erythema* ; Female ; Humans ; Incidence ; Recurrence ; Seasons ; Thorax ; Tuberculosis, Pulmonary ; Ulcer

No abstract available.
Chungcheongnam-do* ; Humans ; Infant* ; Sex Ratio*

Immunohistochemical study for c-erbB-2 oncoprotein was performed on paraffin sections of 76 primary breast carcinomas to determine the relationship between expression of c-erbB-2 and various clinicopathological prognostic indicators, including the expression of epidermal growth factor receptor (EGFR). Positive reaction for c-erbB-2 oncoprotein revealed an intense red granular staining predominantly located at the tumor cell membrane, with some cells exhibiting a weak cytoplasmic staining as well. The epithelial cells of the normal lobule and duct showed a negative reaction. Positive reaction for EGFR revealed a granular staining in the cytoplasm and the cell membrane of the tumor cells. Some tumors showed a positive EGFR staining in the epithelial cells of normal duct and lobule. Twenty six of 76 cases (34.2%) of primary breast carcinomas revealed a positive reaction for c-erbB-2 oncoprotein, and 28 cases (36.8%) were positive for EGFR. Expression of c-erbB-2 oncoprotein and EGFR was evident in 37.7% and 40.6% of 69 classic invasive ductal carcinomas, respectively. None of the other histological types showed a positive reaction. Expression of c-erbB-2 oncoprotein was strongly associated with tumor size(p=0.0015), histologic grade(.p=0.0175), vascular invasion(p=0.0043), and lymph node metastasis(p=0.0024), but not with age at diagnosis(p=0.1836). No significant association was found between expression of c-erbB-2 oncoprotein and EGFR. Co-expression of c-erbB-2 oncoprotein and EGFR was also strongly associated with tumor size (p=0.0029). These results suggest that c-erbB-2 oncoprotein is biologically distinct from EGFR, and may be used as a prognostic indicator of breast carcinoma due to its strong association with various clinicopathological prognostic factors.

In the present study, we have tried to isolate and identify herpes simplex virus type 2(HSV 2) from clinical specirnens, which were inoculated into Vero cell line and grown. Eight strains of viruses were isolated from 20 suspected cases diagnosed from the pr ivate clinics in Seoul. Viruses isolated from 4 rnale and 1 female cases with active lesion were identified to the HSV 2 by indirect immunofluorescence using monoclonal antibody to HSV-2. In addition, morphology of the isolated viruses were observed under electron microscope.
Female ; Fluorescent Antibody Technique, Indirect ; Herpes Simplex* ; Herpesvirus 2, Human* ; Humans ; Seoul ; Simplexvirus* ; Vero Cells

OBJECT: In order to compare several Obstetric characteristics and outmmes of teenage pregnancy. METHODS: The 10 year clinical records of 11,583 women undergoing Cesarean section and delivery were reviewed in the department of Obstetrics and Gynecology, Incheon Christian Hospital from July 1, 1989 to June 30, 1999. There were seventy-eight pregnancies under age 20 and we compared them with two hundred pregnancies aged 20-29 who were randomly chosen during the same periods as the control group. RESULT: The following results were obtained. The proportion of birth by teenagers increased from 0.5% of all birth in 1989 to 2.61% in 1999. The most of cases were in high teen group, age 14- 19.The majority(50.5%) were in the age of 19. Seventy two cases(92.3%) had no previous pregnant history. Six cases had one previous pregnant history. The frequencies of prenatal care were significantly lower than that of the control group(p<0.05). The mean gestational period was 36+4weeks, and showed significant difference between the study group and the control group(39+3 weeks). The incidence of preterm labor was significantly different between the two proups(p<0.05). But the incidence of postterm delivery were not significantly different between the two groups. The mean weight gain of pregnant teenagers revealed 10.64kg, significantly less profound than the control group. The matemal weight gain of control group revealed 12.95kg, respectively. The mean birth weight(2.54kg) of infant was significantly less profound than the control group. The incidence of birth of small for gestational age(birth weight 1,500-2,499gm ; 14.5%) was significantly increased among study group than the control group(1%). The rate of abdominal delivery(21.8%) were not significantly decreased than the control group(47%). The incidence of cephalopelvic disproportion and malpresentation for cesarean section were somewhat higher than the control group, and were statistically significant(p<0.05). During the antepartun period, anemia, pyelonephritis, and preterm labor occurred more frequently in the teenage pregnancy than the control group, but not statistically significant. Among postpartum complications, incidence of anemia(51.3%) increased significantly. The perinatal mortality, intrauterine growth retardation, congenital anomaly occurred more frequently than the control group. CONCLUSION: These results show that pregnancy of teenage will be comeout high risk and complications. And then we will be more concern and study about teenage pregnancy.
Adolescent ; Anemia ; Cephalopelvic Disproportion ; Cesarean Section ; Female ; Fetal Growth Retardation ; Gynecology ; Humans ; Incheon ; Incidence ; Infant ; Obstetric Labor, Premature ; Obstetrics ; Parturition ; Perinatal Mortality ; Postpartum Period ; Pregnancy ; Pregnancy in Adolescence* ; Prenatal Care ; Pyelonephritis ; Weight Gain

Primary ovarian transitional cell carcinoma is extremely rare tumor. The histologic subtype was divided from malignant Brenner tumor due to it's own histologic characteristics and chemosensitive nature. Most of recent studies revealed that transitional cell carcinoma has a good response to chemotherapy and long-term survival. Recent histopathologic reports show that transitional cell carcinoma of the bladder and of the ovary are immunophenotypically different. We experienced a case of primary ovarian transitional cell carcinoma, and report this case with a brief review of the concerned literatures.
Brenner Tumor ; Carcinoma, Transitional Cell* ; Drug Therapy ; Female ; Ovary ; Urinary Bladder

Cosmetic dermatitis of the eyelids may be caused not only by eye make-up but also by cosmetics used elsewhere and conveyed by the fingers to the eyelids. The thin skin of the eyelid is highly susceptible to contact dermatitis, particularly from cosrnetics. A 28 year old female was reported to have contact dermatitis caused by stearic acid in eye cosmetics. The skin lesiens of this patient showed erythematous, edematous, vesicular ruptions on both the upper and lower eyelids. The patch test results were positive for both cornmercial eyeliner and fluid mascara on the second and fourth day. Many of all the ingredients in the eyeliner and fluid mascara, only stearic acid gave positive result on patch tests.
Adult ; Dermatitis ; Dermatitis, Contact* ; Eyelids ; Female ; Fingers ; Humans ; Patch Tests ; Skin

No abstract available.
Biliary Tract*

Clear cell sarcoma of tendon and aponeuroses is slow growing and painless. It occur chiefIy in young adults, predominates in women and is most common in the region of the foot and knee. It is intimately bound to tendons or aponeuroses and is composed of srnall nest or aggregates of round or fusiform, pale staining cells showing prominent nucleoli. And it is tend to recur and to resuIt in eventual development of metastatic growth after a protracted clinical ccurs. Herein, we report a case of clear cell sarcorna of tendon anu aponeuross of metatarsophalangeal joint area between 2nd and 3rd light of left foot. The patient, 50-year-old female had a slow groving, asymptomatic, slightly eevated, emooth surfaced and normal skin colored mass for 2 years. Histopatholcigic tindings in dermis revealed nests of atypical polygonal or monotonous cells. Each cell had vesicular or hyperchrornatic nucleus with prominent nucleoli, occcasionally mitotic figure and abundant eosinophilic cytoplasm. For. treatment, transmetatarsal amputation was done.
Amputation ; Cytoplasm ; Dermis ; Eosinophils ; Female ; Foot* ; Humans ; Knee ; Metatarsophalangeal Joint ; Middle Aged ; Sarcoma, Clear Cell* ; Skin ; Tendons ; Young Adult

To investigate the factors affecting the visual outcome after otherwise successful retinal reattachment surgery in rhegmatogenous retinal detachment involving macula, we performed a retrospective surgvey on 170 eyes encountered properly for this study. Preoperative variables used in this series included age of patients, duration of macular detachment, preoperative visual acuity, extent of detached retina, distance between breaks, and number, shape and location of breaks. We achieved visual acuities of 20/50 or better in 49% (83 of 170 eyes) after retinal reattachment surgery. Factors related to the favorable visual outcome (20/50 or better) were macular detachment lasting less than one month, preoperative visual acuities of 20/200 or better, extent of retinal detachment of 3Q or less, and detachment with tears located at or anterior to the equator. There was no relationship between the visual outcome and the type and the number of the breaks. Of all these variables, preoperative visual acuity has the closest correlation with the final visual results after anatomically successful reattachment surgery.
Humans ; Retina ; Retinal Detachment* ; Retinaldehyde* ; Retrospective Studies ; Visual Acuity