Sixty-six cases of erythena nodosum(EN) and erythema induraturn(EI) were examined pathologically and clinically. Pathologically 23 cases were erythema nodosum, 43 cases were erytherna induratum. Pathological diagnosis made without any prior knowledge of the clinical and laboratory data. Clinical manifestations were reviewed on basis of pathological diagnosis. The results are as follows; l. EN and EI mainly occurred in female, age of twenties and during spring season. There was no difference in sex, age and seasonal incidence between EN and EI. 2. Both EN and EI affected chiefly the shins. EI was more common than EN in cases of calf involvement. 3. Tenderness and systemic symptoms developed more often in EN, while ulcers occurred only in EI. 4 EI had relatively long duration. There was no difference in the recurrence rate between EN and EI. 5. Pulmonary tuberculosis was found only in El on chest X-rays. 6. Clinical and pathological diagnosis was identical in almost cases of EN but those were variable in case of EI.
Diagnosis ; Erythema Induratum* ; Erythema Nodosum* ; Erythema* ; Female ; Humans ; Incidence ; Recurrence ; Seasons ; Thorax ; Tuberculosis, Pulmonary ; Ulcer

No abstract available.
Chungcheongnam-do* ; Humans ; Infant* ; Sex Ratio*

Immunohistochemical study for c-erbB-2 oncoprotein was performed on paraffin sections of 76 primary breast carcinomas to determine the relationship between expression of c-erbB-2 and various clinicopathological prognostic indicators, including the expression of epidermal growth factor receptor (EGFR). Positive reaction for c-erbB-2 oncoprotein revealed an intense red granular staining predominantly located at the tumor cell membrane, with some cells exhibiting a weak cytoplasmic staining as well. The epithelial cells of the normal lobule and duct showed a negative reaction. Positive reaction for EGFR revealed a granular staining in the cytoplasm and the cell membrane of the tumor cells. Some tumors showed a positive EGFR staining in the epithelial cells of normal duct and lobule. Twenty six of 76 cases (34.2%) of primary breast carcinomas revealed a positive reaction for c-erbB-2 oncoprotein, and 28 cases (36.8%) were positive for EGFR. Expression of c-erbB-2 oncoprotein and EGFR was evident in 37.7% and 40.6% of 69 classic invasive ductal carcinomas, respectively. None of the other histological types showed a positive reaction. Expression of c-erbB-2 oncoprotein was strongly associated with tumor size(p=0.0015), histologic grade(.p=0.0175), vascular invasion(p=0.0043), and lymph node metastasis(p=0.0024), but not with age at diagnosis(p=0.1836). No significant association was found between expression of c-erbB-2 oncoprotein and EGFR. Co-expression of c-erbB-2 oncoprotein and EGFR was also strongly associated with tumor size (p=0.0029). These results suggest that c-erbB-2 oncoprotein is biologically distinct from EGFR, and may be used as a prognostic indicator of breast carcinoma due to its strong association with various clinicopathological prognostic factors.

In the present study, we have tried to isolate and identify herpes simplex virus type 2(HSV 2) from clinical specirnens, which were inoculated into Vero cell line and grown. Eight strains of viruses were isolated from 20 suspected cases diagnosed from the pr ivate clinics in Seoul. Viruses isolated from 4 rnale and 1 female cases with active lesion were identified to the HSV 2 by indirect immunofluorescence using monoclonal antibody to HSV-2. In addition, morphology of the isolated viruses were observed under electron microscope.
Female ; Fluorescent Antibody Technique, Indirect ; Herpes Simplex* ; Herpesvirus 2, Human* ; Humans ; Seoul ; Simplexvirus* ; Vero Cells

To evaluate characteristic CT findings of orbital pseudotumor and to define differentialpoints from other pathology, the authors retrospectively reviewed CT of 19 patients who were prooen to have orbital pseudotumor by clinical course and, in some cases, biopsy. A variety of CT findings including extraocular muscle thickening(11 cases), streaky infiltration of retroorbital fat(11 cases), mass formation(10 cases), optic nerve thickening (6 cases), conjunctival thickening (5 cases), scleral thickening(4cases), enlarged lacrimal gland(4 cases) and destruction of orbital bone (2 cases) were observed. Thickening of the anterior portion and irregular margin were characteristic findings of extraocular muscle and optic nerve lesions. Mass formation predominantly occurs in the anterior portion of the orbit. In most cases more than two orbital structures are involved by lesion.
Biopsy ; Humans ; Optic Nerve ; Orbit* ; Orbital Pseudotumor* ; Pathology ; Retrospective Studies

PURPOSE: To report a case of Pott's puffy tumor from a recurrent upper eyelid abscess. CASE SUMMARY: A 73-year-old male visited our clinic with recurrent upper eyelid abscess over the previous 3 months. The patient did not have any evidence of external injuries, systemic inflammations, or any other specific findings. The best corrected visual acuity was 0.9 in the right and 0.5 in the left eye with normal IOP. Enhanced CT revealed a focal low density mass (11.3 x 12.6 x 10 mm) with peripheral enhancement. An excisional biopsy was performed. Histopathologic examination revealed chronic inflammation and granulation tissue formation and the patient was diagnosed with Pott's puffy tumor. The patient experienced no discomfort after the excision biopsy. At the 14-month follow-up, there were no signs of recurrence. CONCLUSIONS: Although rare, Pott' puffy tumor should be considered in the differential diagnosis of upper eyelid mass.
Abscess ; Biopsy ; Diagnosis, Differential ; Eye ; Eyelids ; Follow-Up Studies ; Granulation Tissue ; Humans ; Inflammation ; Male ; Pott Puffy Tumor ; Visual Acuity

Clear cell sarcoma of tendon and aponeuroses is slow growing and painless. It occur chiefIy in young adults, predominates in women and is most common in the region of the foot and knee. It is intimately bound to tendons or aponeuroses and is composed of srnall nest or aggregates of round or fusiform, pale staining cells showing prominent nucleoli. And it is tend to recur and to resuIt in eventual development of metastatic growth after a protracted clinical ccurs. Herein, we report a case of clear cell sarcorna of tendon anu aponeuross of metatarsophalangeal joint area between 2nd and 3rd light of left foot. The patient, 50-year-old female had a slow groving, asymptomatic, slightly eevated, emooth surfaced and normal skin colored mass for 2 years. Histopatholcigic tindings in dermis revealed nests of atypical polygonal or monotonous cells. Each cell had vesicular or hyperchrornatic nucleus with prominent nucleoli, occcasionally mitotic figure and abundant eosinophilic cytoplasm. For. treatment, transmetatarsal amputation was done.
Amputation ; Cytoplasm ; Dermis ; Eosinophils ; Female ; Foot* ; Humans ; Knee ; Metatarsophalangeal Joint ; Middle Aged ; Sarcoma, Clear Cell* ; Skin ; Tendons ; Young Adult

To investigate the factors affecting the visual outcome after otherwise successful retinal reattachment surgery in rhegmatogenous retinal detachment involving macula, we performed a retrospective surgvey on 170 eyes encountered properly for this study. Preoperative variables used in this series included age of patients, duration of macular detachment, preoperative visual acuity, extent of detached retina, distance between breaks, and number, shape and location of breaks. We achieved visual acuities of 20/50 or better in 49% (83 of 170 eyes) after retinal reattachment surgery. Factors related to the favorable visual outcome (20/50 or better) were macular detachment lasting less than one month, preoperative visual acuities of 20/200 or better, extent of retinal detachment of 3Q or less, and detachment with tears located at or anterior to the equator. There was no relationship between the visual outcome and the type and the number of the breaks. Of all these variables, preoperative visual acuity has the closest correlation with the final visual results after anatomically successful reattachment surgery.
Humans ; Retina ; Retinal Detachment* ; Retinaldehyde* ; Retrospective Studies ; Visual Acuity

BACKGROUND: The end-tidal carbon dioxide (ETCO2) is defined as a partial pressure of carbon dioxide at the end of an exhaled breath. And it has been found to correlate with cardiac output during cardiopulmonary resuscitation (CPR) in animal model. The purpose of this study is to determine that the assessment of ETCO2 could provide a highly sensitive predictor of return of spontaneous circulation (ROSC) during CPR. METHODS: Prospective, observational study was performed from Oct 1996 to Mar 1997 at the Severance hospital. All patients were endotracheally intubated and connected immediately to mainstream capnography sensor. We measured ETCO2 with Escort II model 20100 monitor(Medical Data Electronics, Inc, USA). It works on the principle of nondispersed infrared absorption with radiometric single beam optics. RESULTS: This study included 70 patients (52 were men) with a mean age of 54+/-15 years. ROSC was obtained in 43 patients. The initial ETCO2 averaged 15.5 +/-8.2 mmHg in survivors and 6.5+/-5.3 mmHg in nonsurvivors (p<0.01), and during the first 20 minutes of CPR, the maximal ETCO2 averaged 29.7+/-10.3 mmHg in survivors and 10.2+/-8.9 mmHg in nonsurvivors (p<0.01). ETCO2 was not significantly different in relation to initial rhythm, survival time after ROSC and possible cause of arrest. There is no cutoff value of ETCO2 satisfying greater than 90% of both sensitivity and specificity in predict ROSC. When maximal ETCO2 was less than 12 mmHg, we observed sensivity of 100% in predicting ROSC. CONCLUSION: Our results demonstrate that ETCO2 measurement represents a valuable, noninvasive, and clinical tool for monitoring patients during CPR.
Absorption ; Capnography ; Carbon Dioxide* ; Carbon* ; Cardiac Output ; Cardiopulmonary Resuscitation* ; Humans ; Models, Animal ; Observational Study ; Partial Pressure ; Prospective Studies ; Sensitivity and Specificity ; Survivors

The study presents the application of STR polymorphisms to male identification in the cases of a serial rapist in Korea. Since October 2000 a rapist from Cheongju city (a town located in central district) committed at least 36 rapes. DNA profiles obtained from semen stains, buccal cells and tongue tissue left at the scenes of crime and vaginal swabs of victims gave information that one and the same man had committed all the rapes. The Y-chromosome haplotype (12 loci) obtained was used for the identification process of rapist in mixed genotypes including victim's alleles. The crime scene data were referred from investigating police authorities described the relationship of victim to the offender, victim's age, time and place of sexual assault and rape locations. The behavioural analysis of crime scenes showed more similarities than differences for related crimes. These components were usually assessed in terms of proximity in time and space. Certain crime scene aspects of a serial rapist help identify components of offender spatial behaviour. As a result of this work, future research on the geography of rape and behavioural aspects of rapist will be directed towards those aspects of offences, which have been identified as relevant to the distance between an offender's base, and the site where he approached his victim.
Alleles ; Chungcheongbuk-do ; Coloring Agents ; Crime* ; Criminals ; DNA ; Genotype ; Geography ; Haplotypes ; Humans ; Korea ; Male* ; Police ; Rape ; Semen ; Tongue