PURPOSE: The aim of this study is to investigate the biomechanical and histological changes in the muscles after tendon injury that have been little studied previously. MATERIALS AND METHODS: Triceps insertion was tenotomized on the left hidlimbs of 60 rabbits. Mechanical extension testing with Instron (rate: 10 mm/min) was performed 1, 2, 4, 8, 12 and 16 weeks after tenotomy in vivo. A load deformation curve was obtained, and this was analyzed in terms of strength and deformation at the elastic limit and at the point of maximal load. Histologic changes were observed after H < E staining and Matson s trichrome staining to measure the percentage area of collagen fibers. RESULTS: Between weeks 1 and 4, the excursion range fell gradually, and after that period, this value showed little changes. After its initial period of disequilibrium, the muscle regained its elastic nature within its newly formed excursion range. The average amount of collagen fibers increased gradually after tenotomy until 8th week. CONCLUSIONS: unless tendon ruptures are repaired early, the accompanying muscle would be irreversibly damaged, both bimechanically and histologically.
Collagen ; Muscles ; Rabbits ; Rupture ; Tendon Injuries ; Tendons ; Tenotomy*

Rheumatoid arthritis is a chronic inflammatory systemic disease of young or middle aged adults, characterized by destructive and proliferative changes in synovial membrane, periarticular structure, skeletal muscle and perineural sheaths. Eventually, joints are destroied, ankylosed and deformed. Moderate anemia is occured frequently in rheumatoid arthritis patients, and these patients show abnormalities of iron metabolism such as lower serum iron concentration and occurance and distribution of iron in the synovial membrane. It has been suggested that the mechanism of iron deposits in rheumatoid arthritis is continuous oozing of blood from vascular granulation tissue into the synovial cavity and this lead the patient to anemia. We collected samples from serum and knee joint fluid in 21 cases of rheumatoid arthritis for chemical estimation of the ferritin concentration by radioimmunoassay, and compared with that of osteoarthritis. The following results were obtained: 1. The mean hemoglobin concentration(11.4gm %) in rheumatoid arthritis was lower than osteoarthritis(13.4gm %). 2. The mean serum ferritin concentration(118. 4ng/ml) in rheumatoid arthritis was lower than osteoarthritis(135. 6ng/ml), on the contrary in synovial fluid rheumatoid arthritis(279.8ng/ml) showed higher than osteoarthritis(190. 4ng/ml). 3. The mean ratio of synovial fluid ferritin on serum ferritin was 2. 36 in rheumatoid arthritis, in contrast with l. 4 in osteoarthritis. There was significant correlation between the ferritin concentration in synovial fluid and serum. 4. Serial check of ferritin concentration in synovial fluid during treatment would be thought meaningful criteria for determination of progress.and effectiveness of treatment.
Adult ; Anemia ; Arthritis, Rheumatoid ; Ferritins ; Granulation Tissue ; Humans ; Iron ; Joints ; Knee Joint ; Metabolism ; Middle Aged ; Muscle, Skeletal ; Osteoarthritis ; Radioimmunoassay ; Synovial Fluid ; Synovial Membrane

No abstract available.
Snake Bites* ; Snakes*

No abstract available.
Chungcheongnam-do* ; Humans ; Infant* ; Sex Ratio*

No abstract available.

A clinical review was made on 2,191 cases of general pediatric surgery under the age of 15 years which were operated upon at the Divisionof Pediatric Surgery, Department of Surgery, Chonnam University Hospital from January 1988 to December 1997. The number of operations in pediatric age were 13,144 (13.2%) out of total 99,555 operations at Chonnam University Hospital and the most prevalent age group was under 1 year of age (14.3%). The number of operations in Divisionof General Pediatric Surgery were 2,191 (16.7%) out of total 13,144 operations in pediatric age and the incidence of patients under 1 year of age in general pediatric surgery was 42.9% (941/2,191). The prevalent diseases under 1 month of age were anorectal malformations (20.6%) and hypertrophic pyloric stenosis (20.3%) and between 1 month to 1 year of age were inguinal hernia (32.4%) and intussusception (19.6%). The total motality rate in neonatal intensive care unit was 31.3%. Gastroschisis presented highest mortality.
Gastroschisis ; Hernia, Inguinal ; Humans ; Incidence ; Infant, Newborn ; Intensive Care, Neonatal ; Intussusception ; Jeollanam-do ; Mortality ; Pyloric Stenosis, Hypertrophic

No abstract available.
Aluminum Oxide* ; Dental Porcelain*

No abstract available.
Arthroplasty* ; Knee*

No abstract available.
Patellar Dislocation*