1.Study on the treatment of childhood acute lymphoblastic leukemia.
Sang Oh NA ; Hee Young SHIN ; Hyo Seop AHN ; Sang Kyu PARK
Journal of the Korean Cancer Association 1992;24(3):390-400
No abstract available.
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
2.A case of pancytopenia associated with mycoplasmal pneumonia.
Young Mee YOO ; Beom Soo PARK ; In Sang JEON ; Hee Young SHIN ; Hyo Seop AHN
Journal of the Korean Pediatric Society 1991;34(6):826-831
No abstract available.
Pancytopenia*
;
Pneumonia*
3.A nonfamilial case of multiple juvenile polyposis.
Jin Seop SHIM ; Sang Mook CHOI ; Eun Mi KIM ; Jae Ock PARK ; Sang Jhoo LEE ; Chan Sup SHIM ; Chul MOON
Journal of the Korean Pediatric Society 1992;35(6):851-861
No abstract available.
4.Acute megakaryoblastic leukemia in children.
Hong Hoe KOO ; Eun Sil DONG ; Hye Jung PARK ; Hee Young SHIN ; Hyo Seop AHN ; Sang Kyu PARK
Journal of the Korean Pediatric Society 1993;36(1):9-16
We analyzed the clinical and laboratory features of ten children with acute megakaryoblastic lukemia (M7)and compared the findings with those reported in the literature. The diagnosis was supprted by ultrastructural examination of platelet peroxidase or immunophenotyping for glycoprotein IIb/IIIa. Of the ten children, five were girls and five were boys. The median age at diagnosis was 13 months. Two patients had prominent myelofibrosis and one patient had Down syndrome. Nine patients were treatd with low-dose cytosine arabinoside (10mg/m2)administered intravenously, or subcutaneously, or intramuscularly, twice daily in 21 day courses. Seven patients achieved hematologic response and three patients are alive without evidence of disease. The 4 year event free survival rate was30.0%. It is our impression that the prevalence of acute megakaryoblastic leukemia has been under-estimated, and low-dose cytosine arabinoside treatment may be of value in its management. This approach may be particularily useful in hospitals with scarce well-equipped facilities, since this protocol does not induce profound marrow hypoplasia and intensive supportive measures are not required as they would be with the use of more aggressive drug combination.
Blood Platelets
;
Bone Marrow
;
Child*
;
Cytarabine
;
Diagnosis
;
Disease-Free Survival
;
Down Syndrome
;
Female
;
Glycoproteins
;
Humans
;
Immunophenotyping
;
Leukemia, Megakaryoblastic, Acute*
;
Megakaryocyte Progenitor Cells
;
Peroxidase
;
Prevalence
;
Primary Myelofibrosis
5.Carcinomas in childhood.
Hong Hoe KOO ; Kyung Duk PARK ; Hee Young SHIN ; Hyo Seop AHN ; Sang Kyu PARK ; Hye Lim JUNG
Journal of the Korean Pediatric Society 1992;35(10):1369-1376
No abstract available.
6.Scrotal Blunt Trauma: 3 Cases.
Dong Soo PARK ; Jae Seop SHIN ; Sang Yol MAH
Korean Journal of Urology 1988;29(5):889-892
Because of its motility and position, the scrotum is infrequently injured after blunt trauma. We have recently experienced traumatic testicular torsion, testicular rupture, and epididymal rupture with abscess formation after blunt scrotal trauma. We have explored early and treated properly.
Abscess
;
Rupture
;
Scrotum
;
Spermatic Cord Torsion
7.A Case of Mucinous Cystadenocarcinoma in a Premenarchal Girl.
Hong Hoe KOO ; Sang Oh NA ; In Sang JEON ; Hyo Seop AHN ; Wan Suk PARK ; Suk Koo LEE ; Kwi Won PARK ; Chong Jai KIM ; Je Geun CHI
Journal of the Korean Pediatric Society 1990;33(1):124-128
No abstract available.
Cystadenocarcinoma, Mucinous*
;
Female*
;
Humans
;
Mucins*
8.Changes in Heart Rate during and after Exercise Treadmill Test as Prognostic Factor in Cardiovascular Disease.
Hyung Seop KIM ; Ju Hwan LEE ; Yong Seop KWON ; Hyun Sang LEE ; Dong Hun YANG ; Hun Sik PARK ; Yong Keun JO ; Shung Chull CHAE ; Jae Eun JUN ; Wee Hyun PARK
Korean Circulation Journal 2004;34(2):170-177
BACKGROUND AND OBJECTIVES: Many studies have established risk factors for cardiovascular diseases. The Duke treadmill score has gained widespread acceptance for prognosis and diagnosis in cardiac diseases. Recently, changes in heart rate during and after exercise have also been studied to predict the prognosis of cardiac diseases. We examined the relationship between the incidence of cardiovascular events and exercise capacity, achievement of 85% maximal predicted heart rate (MPHR) or heart rate recovery (HRR) after a routine exercise treadmill test. SUBJECTS AND METHODS: We studied 88 patients with chest pain who were over the age of 30. They were referred for exercise treadmill test for assessment of chest pain and underwent symptom-limited, exercise test with a cool down period of 30 seconds. HRR was defined as the difference in heart rate between peak exercise and 1 minute after exercise. Delta heart rate (DHR) was defined as the difference in heart rate between resting and peak exercise. Other parameters in the exercise test were also measured. RESULTS: Cardiovascular events were found in 13 of the 88 patients. In the events group, age, peak heart rate in exercise, ST depression, maximal exercise capacity, HRR, DHR and achievement of 85% MPHR were all significant variables. There was a favorable prognosis in the patients with a value of HRR >22 beats/minute and a value of DHR >83 beats/minute. Even after adjusting for age, sex, ST depression and left ventricular hypertrophy, the parameters of maximal exercise capacity, HRR, DHR, and achievement of 85% MPHR remained predictive prognostic factors in cardiovascular events. CONCLUSION: Parameters in exercise treadmill test, such as maximal exercise capacity, HRR, DHR and achievement of 85% MPHR, appear to provide additional information and are important variables associated with the prediction of risk in cardiac events.
Cardiovascular Diseases*
;
Chest Pain
;
Depression
;
Diagnosis
;
Exercise Test*
;
Heart Diseases
;
Heart Rate*
;
Heart*
;
Humans
;
Hypertrophy, Left Ventricular
;
Incidence
;
Prognosis
;
Risk Factors
9.The Clinical Characteristics of Mycoplasmal Pneumonia in Adults.
Jin Ho KIM ; Doo Seop MOON ; Dong Suck LEE ; Ik Soo PARK ; Kyeung Sang LEE ; Ho Joo YOON ; Dong Ho SHIN ; Sung Soo PARK ; Jung Hee LEE
Tuberculosis and Respiratory Diseases 1995;42(2):175-183
BACKGROUND: The incidence of mycoplasmal pneumonia is predominantly at childhood and early adulthood, but in adults, its incidence is low and its symptoms and physical findings are nonspecific. The definite diagnosis of M. pneumoniae pneumonia can be made by sputum culture, but requires several weeks for positive results, and the early diagnosis must initially be based on the serologic tests and appropriate clinical findings. Thus, we evaluated the clinical aspects of M. pneumoniae pneumonia in the adults patients. METHOD: Among the admitted patients due to pneumonia, the definite diagnosis is anti-M. pneumoniae antibody titer of > 1:40 and a single cold agglutinin titer of > 1:64. The presumptive diagnosis is anti-M. pneumoniae antibody titer of > 1:40 or a single cold agglutinin titer of > 1:64 and the clinical characteristics or chest X-ray findings are compatible with M. pneumoniae pneumonia. We studied the age and sex distribution, seasonal distribution, clinical symptoms, physical findings, serologic test, chest X-ray findings, treatment and its progression. RESULTS: 1) The age distribution was even and the ratio of male to female was 1:1. 2) The monthly distribution was most common in January(16.7%) and the seasonal distribution in autumn and winter(autumn: 30%, winter: 33.3%). 3) The cold agglutinin titers were higher than 1:64 in 12 cases(40%), and reached the peak level around 2 weeks from onset and antimycoplasma antibody titers were higher than 1:160 in 5 cases(16.7%). 4) On the chest X-ray, pulmonary infiltration was noted in 28 cases(93.3%) among 30 cases and right lower lobe involvement was the most common(33.3%) and both lower lobe involvement was noted in 7 cases(23.3%). 5) The mean treatment duration was most common(33.3%) in 1 week to 2 weeks after admission and 26 cases(86.7%) were improved within 4 weeks. 6) On admission, there was fever(> or =38.9degreesC) in 17 cases(56.7%), and the fever subsided in 12 cases(70%) within 3 days after treatment using erythromycin. CONCLUSION: The mycoplasmal pneumonia in adults shows milder clinical patterns than that in childhood and can be completely recovered without complication by early diagnosis and treatment.
Adult*
;
Age Distribution
;
Diagnosis
;
Early Diagnosis
;
Erythromycin
;
Female
;
Fever
;
Hospital Distribution Systems
;
Humans
;
Incidence
;
Male
;
Pneumonia*
;
Seasons
;
Serologic Tests
;
Sex Distribution
;
Sputum
;
Thorax
10.Immunologic marker analysis in acute myeloid leukemia.
Myoung Hee PARK ; Won Il OH ; Hee Jung KANG ; Han Ik CHO ; Sang In KIM ; Byoung Kook KIM ; Seonyang PARK ; Hyo Seop AHN ; Hee Young SHIN
Korean Journal of Hematology 1991;26(2):253-261
No abstract available.
Biomarkers*
;
Leukemia, Myeloid, Acute*