1.Surgical Treatment of Parkinson's Disease.
Journal of the Korean Neurological Association 1986;4(1):38-42
No abstract available.
Parkinson Disease*
2.Observation about Dapsone-Resistant Cases of Leprosy Partients by Clinical and Bacteriological Aspects.
Korean Journal of Dermatology 1981;19(1):39-46
Fifteen hundred seventy-one leprosy patients registered in the leprosy Mission Hospital from Mar. 1957 to Sep. 1980 were investigated for dapsone resistance by clinical and bacteriological aspects. The results are as follows: There were 29 suspected dapsone-resistant cases out of a total 1571 registered leprosy patients (1. 85%), 26 of 650 of lepromatous type(4. 00%), and 3 of 164 of borderline type (l. 83%). In 1969, we observed the first case if suspected dapsone-resistant leprosy. Since then, suspected dapsone-resistant cases increased and we observed as many as 8 cases in 1977. But frequency of cases has decreased since 1978. (countinued..)
Dapsone
;
Humans
;
Leprosy*
;
Missions and Missionaries
3.Tuberous Sclerosis Occuring through 3 Generations.
Jong Seop HA ; Byung Jin LEE ; Sang Lip CHUNG
Korean Journal of Dermatology 1980;18(6):605-611
Tuberous sclerosis is a complex neurocutaneous disease inherited as an autosomal dominant pattern, which is characterized by facial angio-fibroma, mental retardation and seizures. Many cases have been reported in the literatures, but familial cases are relatively rare. We present 9 cases of tuberous sclerois occuring througb 3 generations, which are 3 cases of angiofibroma, mental retardation and seizures, 2 cases of facial angiofibroma and seizures, 1 case of mental retardation and seizures and 3 cases who showed facial angiofibroma only. Two brothers in this family reveald icthyosis vulgaris without tuberous sclerosis.
Angiofibroma
;
Family Characteristics*
;
Humans
;
Intellectual Disability
;
Seizures
;
Siblings
;
Tuberous Sclerosis*
4.Two Cases of Bullous Dermatitis Herpetiformis.
Do Young CHOI ; Jong Seop HA ; Sang Lip CHUNG
Korean Journal of Dermatology 1980;18(4):299-305
Dermatitis herpetiformis occurs rarely in childhood and certain features of the disease in children differ from its manifestation in adults. The eruptions are commonly bullous, show little predilection for the typical regional pattern of the adults, may be nonpruritic, have a shorter course, and often are resistant to the usual therapy. A review of literature shows that in patients over 50 years of age or older the tendency is to manifecst predominantly, although not as strikingly for children, a vesicobullous type of dermatitis herpetiformis with large bullae, varying 1 to 5cm or more in diameter. The authors present two cases of bullous dermatitis herpetiformis confirmed by histology; the first case is a 5 year-old boy who has tense bullae, pustules, and pigmentations on the inguinal region, lower abdomen, buttocks, face, and extensor surfaces of the extremities of 1 yars duration; the second case is a 44 year old housewife who has eruptions of vesicles, bullae, and erosion on the buttccks, back, abdomen, ext;remities, oral cavity, and vulva of 15 days' duration. The authors reviewed the relevant literature and discussed the clinicaI feat ures of both cases thoroughly.
Abdomen
;
Adult
;
Buttocks
;
Child
;
Child, Preschool
;
Dermatitis Herpetiformis*
;
Dermatitis*
;
Extremities
;
Humans
;
Male
;
Mouth
;
Pigmentation
;
Transcutaneous Electric Nerve Stimulation
;
Vulva
5.Osteosarcoma-Thirteen-Year Experience
Han Koo LEE ; Sang Hoon LEE ; Chang Seop LEE ; Chung Hoon LEE
The Journal of the Korean Orthopaedic Association 1995;30(2):230-236
Osteosarcoma is the most common primary malignant tumor in the orthopaedic field. Recently, the management of osteosarcoma was evolved in many aspects and the improved results were reported in many articles. The purpose of this study is to evaluate the changes of clinical findings and management modalities in osteosarcoma since 1980. We reviewed 127 osteosarcomas managed from 1980 to 1992. The Enneking surgical stage was as follows; stage I 12 cases, stage II 98 cases and stage III 17 cases. They were subclassified into classic(97 cases), parosteal(12 cases), telangiectatic(5 cases), secondary(4 cases), periosteal(2 cases), gnathic(2 cases), high grade surface(1 cases) and undetermined(4 cases). The disease-free survival rate was evaluated for the patients of stage II classic osteosarcomas treated with amputation(27 cases) or limb-salvage operation(23 cases), and average follow up period of them was 49 months. In 27 cases of amputation adjuvant chemotherapy was administered in 23 cases. And in 23 patients treated with limb-salvage operation, neoadjuvant and adjuvant chemotherapy were done in 19 cases and only adjuvant chemotherapy in 2 cases. The clinical changes since 1980 were as follows: (1) The mean duration from symptom onset to diagnosis was decreased gradually from 6.5 months(1980) to 3.1 months(1992). (2) The proportion of curative surgery was increased from 40%(1980) to 87%(1992) in stage I and II. (3) The proportion of limb-salvage operation was rapidly increased upto 88% since 1985. The 5 year disease-free survival rate of stage II classic osteosarcoma was 36% with amputation and 67% with limb-salvage operation.
Amputation
;
Chemotherapy, Adjuvant
;
Diagnosis
;
Disease-Free Survival
;
Follow-Up Studies
;
Humans
;
Osteosarcoma
6.Treatment of Fixed Lumbosacral Kyphosis by Posterior Vertebral Column Resection: A preliminary report.
Se Il SUK ; Jin Hyok KIM ; Won Joong KIM ; Sang Min LEE ; Yi LIU ; Ewy Ryong CHUNG ; Chang Seop LEE
Journal of Korean Society of Spine Surgery 1998;5(2):307-313
STUDY DESIGN: This is a retrospective study evaluating the efficacy of new surgical technique for treatment of fixed lumbosacral kyphosis. OBJECTIVES: To report a new method of vertebral column resection and to determine its efficacy in the treatment of fixed lumbosacral kyphosis. SUMMARY OF BACKGROUND DATA: The treatment of fixed severe spinal deformity is very difficult and only a few surgical methods are reported. The vertebral column resection from anterior and posterior is a radical method to treat the severe deformity but it has many problems with anterior and posterior approachs. MATERIALS AND METHODS: A new surgical method of vertebral column resection from posterior approach only(PVCR) was carried out in 5 patients of fixed lumbosacral Tb kyphosis from October 1997 to March 1998. The mean age was 43.4 years(range 35-61 years), and four were female and one male. The average postoperative follow-up period was 5.5 months(ranged from 2 months to 12 months). An average of 2.6 vertebrae was resected. The degree of sagittal curves was measured using the Cobb technique preoperatively and postoperatively. the rejional lumbosacral kyphotic angle and compensatory thoracic curvature from 74 to 712. The sagittal imbalance was measured by distance from C7 plumb line to postero-superior corner of 51 using 14 x 36 inch standing lateral radiograph. RESULTS: The sagittal deformities were corrected from an average of kyphosis 37.4 to lodosis 8.4 at lumbosacral level and from an average of lodosis 31.6 to lodosis 8.2 at thoracic level. The sagittal imbalance was improved from an average of +11.7cm to +2.2cm, for a posterior immigration of 9.5cm. The mean operating time was 334 minutes and with an average blood loss of 4338m1. Complication comprised of motor weakness with deep wound infection in one case and superficial wound infection in another case. The transient hip flexor weakness was seen in all the patients. The hip flexor power recovered in 3-4 weeks. The patient of motor weakness and deep infection showed partial motor improvement and complete wound healing at last 2 month follow-up. CONCLUSION: one-stage posterior vertebral column resection is a promising technique for treatment of the severe fixed lumbosacral kyphosis.
Congenital Abnormalities
;
Emigration and Immigration
;
Female
;
Follow-Up Studies
;
Hip
;
Humans
;
Kyphosis*
;
Male
;
Retrospective Studies
;
Spine*
;
Wound Healing
;
Wound Infection
7.Surgical Treatment of Intracranial Artery Giant Aneurysm Using Cardiopulmonary Bypass and Deep Hypothermic Circulatory Arrest: Case Report.
You Nam CHUNG ; Kyung Soo MIN ; Mou Seop LEE ; Dong Ho KIM ; Jong Myeon HONG ; Sang Tai KIM
Journal of Korean Neurosurgical Society 2000;29(12):1657-1663
No abstract available.
Aneurysm*
;
Arteries*
;
Cardiopulmonary Bypass*
;
Circulatory Arrest, Deep Hypothermia Induced*
8.Two Cases of Acute Encephalopathy with Thalamotegmental Involvement and Remained Motor Dysfunction in Infants.
Hyun Hoe KOO ; Won Seop KIM ; Sang Hun CHA
Journal of the Korean Child Neurology Society 2001;9(2):407-410
Acute encephalopathy with thalamotegmental involvement occurs in infants and young children and is thought to be a postviral or postinfectious brain disease. This disease is preceded for several days by fever and symptoms of upper respiratory infection. The symptoms are followed by the rapid evolution of stupor and coma, associated with generalized seizures and decerebrate rigidity. In this disease, the computed tomography (CT) or brain magnetic resonance imaging demonstrate symmetrical focal lesions in the thalami and brainstem tegmentum. We report two cases of acute encephalopathy with thalamotegmental involvement and remaining motor dysfunction in infants.
Brain
;
Brain Diseases
;
Brain Stem
;
Child
;
Coma
;
Decerebrate State
;
Fever
;
Humans
;
Infant*
;
Magnetic Resonance Imaging
;
Seizures
;
Stupor
9.Influence of the Posterior Slope of the Tibial Component on the Maximal Flexion after Total Knee Arthroplasty.
Kyung Chul KIM ; Jae Yeul CHOI ; Joon Sik KIM ; Hwa Jae CHUNG ; Bon Seop KOO ; Sang Yeon WON
Journal of the Korean Knee Society 1998;10(1):13-17
To evaluate the effect of tibial cut with posterior slope in total knee arthroplasty(TKA) surgery on the flexion of the knee, 41 knees(32 patients) with varying degree of the posterior slope were retrospectively reviewed at more than 1 year after operation. Does sloping the tibial cut iurface rnore posteriorly promote increasing of maximal flexion of the knee by elimination of excessive tenaion of the posterior cruciate liga ment The degree of the posterior slope was radiographically measured, awi the change of the degree of the maximal flexion between preoperative and postoperative period was clinimlly measured with a goniometer at the latest follow up more than 1 year after operation. Comparison of the results demonstrated significantly larger degree of rqaximal flexion for the knees that had tibial cut with the degree of the posterior slope, 5 degrees or rnore (p<0.05). We concluded that 5 degrees or more posterior slope in proxirnal tibial cut is one of the important fact()r which could achieve increased flexion of the knee after TKA operation.
Arthroplasty*
;
Follow-Up Studies
;
Knee Joint
;
Knee*
;
Postoperative Period
;
Retrospective Studies
10.Histiocytic necrotizing lymphadenitis in children : association of human herpes virus 8 and Epstein Barr virus.
Hyun A KIM ; Ju Young CHUNG ; Sang Woo KIM ; Sung Jig LIM ; Haeng Seop SHIN
Korean Journal of Pediatrics 2006;49(8):875-881
PURPOSE: The aims of this study were to analyze the clinical characteristics of children with Kikuchi's disease(KD) at a medical center and to investigate the etiologic role of human herpesvirus 8(HHV 8) or Epstein-Barr virus(EBV) in children with KD. METHODS: Twenty six children who were diagnosed as KD between Jan. 1998 and Dec. 2005 were included. Medical records were reviewed on the clinical characteristics of children with KD. Follow up data were collected by chart review and telephone contact. Polymerase chain reaction(PCR) was performed in order to detect HHV 8 DNA, and in situ hybridization(ISH) was perfomed in order to detect EBV RNA from 20 lymph node tissues. RESULTS: There were 15 girls and 11 boys with a mean age of 13 years. Posterior cervical lymph nodes were involved in 72 percent(18/25) of the patients. Extracervical lymphadenopathy was associated in one patient. Fever was an associated symptom in 31 percent(8/26) of the patients. Leukopenia was observed in six (46 percent) patients. The cervical lymphadenopathy usually resolved spontaneously within 6 months. Only one patient had a recurrence of lymphadenopathy with fever during follow-up. No children with KD in our series developed systemic lupus erythematosus. HHV 8 DNA was not amplified by nested PCR in any of the cases, and all cases were negative for EBV RNA by ISH. CONCLUSION: KD should be differentiated as a cause of cervical lymphadenopathy in children. HHV 8 and EBV may not play major causative roles in KD in children.
Child*
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DNA
;
Female
;
Fever
;
Follow-Up Studies
;
Herpesvirus 4, Human*
;
Histiocytic Necrotizing Lymphadenitis*
;
Humans
;
Humans*
;
Leukopenia
;
Lupus Erythematosus, Systemic
;
Lymph Nodes
;
Lymphatic Diseases
;
Medical Records
;
Polymerase Chain Reaction
;
Recurrence
;
RNA
;
Telephone