1.Cultured Chondrocyte Transplantation in the Damaged Growth Plate
The Journal of the Korean Orthopaedic Association 1989;24(6):1529-1534
The growth plate is responsible for longitudinal bone growth and is involved in 6–15% of children's fracture. Of these injuries, 25–35% have been reported to result in some shortening or deformity, but in only 10% are the deformities sufficiently severe to lead to functional problems. The problem of repair of a demaged growth plate in children has never been adequately solved. The purpose of this study is to clarify that allograft of cultured chondrocytes can survive in the growth plate defect and can prevent the angular deformity by avoiding the formation of bone bridge. The chondrocytes were obtained from the rib cartilage of rabbit weighing 500g. The chondrocytes were cultured by socalled micromass culture method. The rabbits were divided two groups; the group I in which medial proximal tibial growth plate was destroyed, and the group II in which the cultured chondrocytes were transplanted into the right medial proximal tibial physeal defect. Each group has 10 rabbits. The tibial growth was observed grossly, radiologically and histologically until 16 weeks after graft. The angular deformity was observed from 3 weeks after operation and histologically the fusion of growth plate was observed in all of group I. In group II, there were no angular deformity and no fusion of growth plate in 7 out of 10 rabbits. Allografted cultured chondrocytes survived and produced matrix in the physeal defects. Through this study it was inferred that allograft transplantation of cultued chondrocytes in the iatrogenical physeal defect is a useful method to keep the physeal growth without cessation. However, further studies will be necessary to prove that the longitudinal growth potential resides in the transplanted chondrocytes as growth plate cartilage.
Allografts
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Bone Development
;
Cartilage
;
Child
;
Chondrocytes
;
Congenital Abnormalities
;
Growth Plate
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Humans
;
Methods
;
Rabbits
;
Ribs
;
Transplants
3.Anterior Interbody Fusion in Unstable Fracture and Fracture
Myung Sang MOON ; In KIM ; Ok Bae KIM
The Journal of the Korean Orthopaedic Association 1981;16(2):265-276
Authors had reviewed the results of 20 anterior cervical fusions performed between 1975 and 1980 to determine which factors were important to a successful result. There had been 18 single level fusions and 2 fusions at two levels, the majority at C and C. The indications for fusion operation were: firstly in acutely traumatized patient was the spine representing radiologically the signs of segmental instability, secondly was the chronic segmental instability in old traumatized spine representing the nuchal rigidity and severe cervicobrachial pain which. was not ceased by conservative treatments. The index of successful fusion was complete relief of pain, loss of cervical rigidity and radiologlcal stability of fused segment indicated by no-movement in flexion-extension lateral radiograms, and the bony bridges between the fused segments. The postoperative stability of spine was assessed by measuring the changes of disc space and kyphotic angle. The result obtained were as follows: 1. Pre-and post-operative immobilization with cervical traction played an immportant role for successful results after fusion: 4–6 weeks of pre-operative traction in acutely injured spine provided the torn soft tissue structures with sufficient time needed for its healing, and 6 weeks of postoperative traction also provided the bone graft with sufficient time needed for its cooperation with graft bed. 2. ln all cases succeasful fusion was obtained. In a case a adjacent level was incorrectly fused, but it was fused soundly in time, while the unstable unfused segment was not fused spontaneously. 3. The fused segment or segments of spine stabilized clinically in 6-8 weeks after fusion operation which was proven by serial radiograms, and solid bony fusion was obtained radiologically averaging in 12 weeks after fusion operation. 4. The average increase of kyphosis after interbody fusion till solid fusion was negligible, averaging 3.0 degrees. 5. The solid fusion occurred in one to 2 weeks earlier in the spines with wedge and axial conpression fractures than the spines with flexion-rotation and shear types of fractures. 6. No further neurogical damage developed after successful fusion.
Dislocations
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Humans
;
Immobilization
;
Kyphosis
;
Muscle Rigidity
;
Spine
;
Traction
;
Transplants
4.Treatment of Femoral Neck Fractures in the Elderly Patients: Comparision of the End Results Between the Groups of Internal Fixation and Endoprosthesis
Myung Sang MOON ; In KIM ; Ok Bae KIM
The Journal of the Korean Orthopaedic Association 1982;17(3):474-484
Authors clinically analysed the end results of the 56 elderly patients having fresh femoral neck fracture who were treated with osteosynthesis procedures and 23 endoprosthesis replacement surgery. All these 79 patients were treated between 1970 and 1979 at the St. Marys Hospital, Seoul. The indications of primary endoprosthesis replacement surgery in femoral neck fractured patients were in elderly patients over 65 years, displaced, comminuted sub capital or transcervical fractures, irreducible fractures, pathological fractures and patients having generalized diseases or senile psychosis. The results for the operated hip joints were assessed by duration of hospitalization, early and late post-operative complication. and the Jessels hip grading method at least post-operative one and half year later. The results obtained were as follows: 1. The average age of the patients were 65 years in 56 cases with initial osteosynthetic group, and 73 years in 23 cases of initial endoprosthesis group. 2. The slip down was the most common cause of injuries. The transcervical type of fracture was 54% of all cases. 3. The eligibility of ambulation was average 34 days after surgery in cases having initial osteosynthesis and 18 days in cases having endoprosthesis. 4. Early post-operative complications such as pneumonia and urethritis etc. were more common in cases of endoprosthesis than in osteosynthesis. But we think these complications were not related with surgery itself and transient. 5. Late post-operative complications in cases of osteosynthesis were avascular necrosis of head (16%), nonunion (9%), osteoarthritis (4%), and deep wound infection (2%), but in cases with endoprosthesis, leg length discrepancy (12%), acetabular erosion (4%) and loosening (4%) in order. 6. We performed the second operation in 12 cases among the 56 patients of osteosynthesis because of post-operative complications. 7. Good end results were obtained 90% in 56 osteosynthesis and 91% in 23 endoprosthesis. Conclusively, author's observation time was relatively short (11/2–3 years) and it is impressed that long term study for the prosthetic group is necessary for the more accurate evaluation of their hip function.
Acetabulum
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Aged
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Femoral Neck Fractures
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Femur Neck
;
Fractures, Spontaneous
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Head
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Hip
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Hip Joint
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Hospitalization
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Humans
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Leg
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Methods
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Necrosis
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Osteoarthritis
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Pneumonia
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Psychotic Disorders
;
Seoul
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Urethritis
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Walking
;
Wound Infection
5.The Boston Brace in Adolescent Idiopathic Scoliosis
Myung Sang MOON ; In Young OK ; Soon Young MOON
The Journal of the Korean Orthopaedic Association 1989;24(6):1605-1611
The results in thrity-six adolescent idiopathic scoliosis patients(thirty-nine curves) who have been treated with the Boston brace are reported. The average follow-up was two years and three months(range, one year to four years ten months). Before treatment, all the patients had a curve that measured 20 to 35 degrees; 26 patients were in Risser sign of zero or 1, 10 patients in Risser sign 2 to 4. Although the magnitude of the curve was generally reduced about 40 percent by the initial application of the brace, a gradual loss of this initial correction was observed both during active treatment and after the wearing of the brace. Although eleven(28.2 percent) of the curves had progressed more than 5 degrees at follow up. Sixty-seven percent of the thoracic curve, 33.3 percent of the thoracolumbar, 27.8 percent of the lumbar curve had progression of more than 5 degrees. Twelve patients wore the brace for sixteen hours a day, 19 patients wore for 16 to 20 hours a day and 5 patients wore more than 20 hours a day. 41.7 percent of sixteen hours bracing, 15,8 percent of 16 to 20 hours bracing and 60 percent of 20 hours bracing had progression of more than 5 degrees. Our finding indicates that the Boston brace prevents deterioration in certain cases but does not convert major deformity into minor ones, and part time bracing can prevent progression of the curve and can even afford some correction.
Adolescent
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Braces
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Congenital Abnormalities
;
Follow-Up Studies
;
Humans
;
Scoliosis
6.Significance of Diagnosis of Soft Tissue and Bone Tumor Utilizing the Fine Needle Aspiration, Cell Blocks, and Franklin-Silverman Biopsy Needle: A Comparative Study of Three Different Methods
Kee Yong HA ; In Young OK ; Myung Sang MOON ; Sang In SHIM
The Journal of the Korean Orthopaedic Association 1982;17(1):29-35
In general, soft tissue and bone tumors are diagnosed clinically by physical findings, laboratory data, and X-ray findings with only limited reliability, and a definite diagnosis must be supported by histopathological evidence. For this purpose, open biopsy routinely has been carried out, but there have been many disadvantages and sometimes followed by surgical complications. The present study was undertaken to compare the cytologic findings of soft tissue and bone lesions with the histological findings. The specimen were obtained by fine needle aspiration and Franklin-Silverman needle. For cytodiagnosis Stormby's cell block of aspirates were utilized. For histological diagnosis small tissue fragments obtained by the Franklin-Silvermans cutting needle were used. Then, the diagnostic accuracy of 3 different methods were compared, and the clinical applicability of those methods as adjunctive diagnostic procedures in the diagnosis of the soft tissue and bone tumors were assessed. The results obtained were as follows: l. In 15 out of the 20 cases (75%) in which clinically and roentgenologically the soft tissue and bone tumors were suspected, sufficient material was aspirated to enable detailed cytological diagnosis possible by fine needle aspiration. ln 13 out of the 15 cases, diagnosis could be made by cytologic findings, which was similar to histologic findings of tissue obtained by Franklin-Silverman needle. 2. In 6 out of the 20 cases, sufficient tissue fluid for cell block preparation were obtained from the tumor tissues. In 5 cases, cytologic findings of cell blocks were consistent with that ot the tissue obtained by Silverman needle. But in one case malignancy was susupected by cytodiagnostic method, and definite diagnosis could not be made. Finally the lesion was found to be malignant schwannoma through the histological study of tissue specimen obtained by Franklin-Silverman needle biopsy. 3. In 19 out of the 20 cases, diagnosis could be made by Franklin-Silverman needle biopsy. 4. Diagnostic accuracy of the lesions by clinical and roentgenological method was 75%, which overall diagnostic accuracy of 3 methods were 86.7% in aspiration cytology, 83.3% in cytodiagosis of cell block and 95% of histodiagnosis of tissue specimen obtained by Franklin-Silverman needle. Through this study it is found that cytodiagnostic method of aspirates and histodiagnosis of the small tissue specimen by Franklin-Silverman needle are very useful adjunctive methods in enhancing the diagnostic accuracy of the soft tissue and bone lesion prior to open biopsy trial.
Biopsy
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Biopsy, Fine-Needle
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Biopsy, Needle
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Cytodiagnosis
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Diagnosis
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Methods
;
Needles
;
Neurilemmoma
7.Comparative Study on the Results of Femoral Osteotomy and Innominate Osteotomy in LCPD
Myung Sang MOON ; In Young OK ; Young Ho SOHN
The Journal of the Korean Orthopaedic Association 1989;24(1):185-192
Methods of treatment of Legg-Calve-Perthes' disease, (L.C.P.D.) are at present generally defined, and the individual approach is now more precise than before. But it is still controversial, particularly in older age groups. We analized the result of intertrochanteric varus osteotomy in 44 hips and innominate osteotomy in 23 hips of L.C.P.D., and compared the former with the later. To find out the influence of the both osteotomies on the femoral head (coxa magna), the relations between the stage and degree of involvement at operation and reult, and the postoperative progression of disease, the cases were analyzed and classified by Elizabethtown's stage and Catterall group. And also the duration of fragmentation stage after osteotomy was observed. Results were as follows: l. At the time of operation 45 hips were in avascular stage, 18 hips in fragmentation stage, and 4 hips in healing stage. 20 hips(29.8%) were classified as group II, 29(43. 3%) group III, and 18(23.1%) group IV. 2. After the osteotmy in case of avasculsr necrosis stage, average duration of fragmentation stage was 6.3 months after femoral osteotomy and 1 year 6 months after innominate osteotomy. 12 among 20 hips were skipped the fragmentation stage, and got into healing stage in case of femoral osteotomy. 3. After the osteotomy at the fragmentation stage, average duration of the fragmentation stage was 9.8 months after femoral osteotomy and 1 year 3 months in case of innominate osteotomy. 4. Regardless of the type of osteotomy, coxa magna was observed more frequently in the case who had surgery at the late stage and severely involoved head at the time of osteotomy. 5. In the case of femoral osteotomy, average preoperative neck shaft angle was 138.5°, and postoperative one was 113.5°. During the follow-up study, 12.0° of revalgarisation took place. 6. The result obtained by femoral osteotomy gave better results than those by innominate osteotomy. Regardless of the type of osteotomy, good results were obtained in case who had surgery at the early stage such as avascular stage, and had mild involvement as such group II.
Follow-Up Studies
;
Head
;
Hip
;
Humans
;
Neck
;
Necrosis
;
Osteotomy
8.Overgrowth after Open Reduction of Femoral Fracture in Children
Myung Sang MOON ; In Young OK ; Tae Hee KIM
The Journal of the Korean Orthopaedic Association 1990;25(5):1391-1396
Femoral fractures are difficult to treat in the child with head or multiple injuries. Traction may fail due to spasticity and restlessness. Poor results after closed reduction have led some authors to advocate open reduction and internal fixation which facilitates overall care. Anatomical reduction with internal fixation leads to limb overgrowth. We report our experience in anatomical open reduction of femoral fracture which had head or multiple injuries or difficult to maintain traction in children at the Kang-Nam St. Mary's Hospital. The results are as follows : 1. Among the 28 cases, there were 20 cases in male and 8 cases in female. Average age was 9.4 years. 2. Plate fixation was used in 27 cases and Kuntscher Kuentscher nail was used in one case. 3. Average union period was 11.5 weeks. There was one delayed union which was completely united in 20 weeks. 4. Average overgrowth of femur was 5.2mm. The overgrowth was related with age and handedness but it was not related with fracture site. For children who have head or multiple injuries or difficult to maintain the skin traction, open reduction with plate fixation appears the most satisfactory treatment. The overgrowth of the femur after open reduction was not significant problems clinically.
Child
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Extremities
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Female
;
Femoral Fractures
;
Femur
;
Functional Laterality
;
Head
;
Humans
;
Male
;
Multiple Trauma
;
Muscle Spasticity
;
Psychomotor Agitation
;
Skin
;
Traction
9.Surgical Management of Untreated Developmental Dislocation of the Hip in Elderly Children
Myung Sang MOON ; In Young OK ; Seon Youl PAEK
The Journal of the Korean Orthopaedic Association 1995;30(5):1147-1153
There are many unanswered questions concerning the natural history of developmental dislocation of the hip. The assessment of impaired function in complete hip dislocation is very subjective. According to Wedge, however, 60 percent of hips seems to present significant problems. The remaining 40 percent gives no pain, but produces an abnormal gait with decreased agility, and important consideration in mordern society. Therefore pediatric orthopaedic surgeon should consider to improve the gait and hip function in the neglected D.D.H in elderly children. The following problem have been debated, for instance: 1) traction prior to open reduction 2) how much shorten the femur 3) what type of pelvic osteotomy should be performed? 4) importance of derotation and varus osteotomy of femur 5) to provide immediate stability of the hip, 6) postsurgery joint stiffness, and 7) avascular necrosis of the femoral head. Above problems are discussed through 38 cases which were above the age of 5 years. The results were as follow: 1) A femoral varus osteotomy provided the hip stability by containing the head in socket and femoral shortening effect. 2) The Preop traction provided the soft tissue release at surgery and decreased the incidence of AVN. 3) The acetabular remodelling was observed until the age of 13 years when concentric relocation of the head was achieved even after the age 8 years. 4) The pelvic osteotomy was not always required in those case of complete dislocation in which the femoral head could be deeply relocated in the acetabulum after femoral osteotomy.
Acetabulum
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Aged
;
Child
;
Dislocations
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Femur
;
Gait
;
Head
;
Hip Dislocation
;
Hip
;
Humans
;
Incidence
;
Joints
;
Natural History
;
Necrosis
;
Osteotomy
;
Traction
10.Skin Graft and Chronic Osteomyelitis
Myung Sang MOON ; Seung Hoon LEE ; In Hyung HAN ; In Young OK
The Journal of the Korean Orthopaedic Association 1973;8(2):175-178
Authors presented the gratifying result of treatment of chronic osteomyelitis with overlying skin defect and/or poor skin condition, which developed the wide skin necrosis after saucerization and resulted the second skin graft necessary. Five cases were treated by primary extensive saucerization of tibia which left a cavity with bleeding walls. The exposed bony surface with bleeding walls was covered by delayed free skin graft when the good granulation covered the bony surface. Through this experience, delayed free skin graft is justified the best procedure in these cases to cover the post-surgical raw bone surface and to have primary healing of the bone infection. A method of hemicylindrical pedunculated skin graft to obliterate the deeply excavated surgical bony defect is introduced.
Hemorrhage
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Methods
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Necrosis
;
Osteomyelitis
;
Skin
;
Tibia
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Transplants