1.A Case of Mucopolysaccharidosis Type I with Spinal Cord Compression.
Sang Myung CHEON ; Min Jeong PARK ; Jae Kwan CHA
Journal of the Korean Neurological Association 2002;20(2):199-201
A 21-year-old woman with gargoyloid face and short trunkal stature showed progressive quadriparesis. Cervical spine MRI showed circumferential compression of cervical spinal cord by thickened dura mater. Elevated urinary dermatan sulfate and decreased enzyme activity of -iduronidase revealed that she has mild form of mucopolysaccharidosis type I. Her weakness was improved with cervical laminectomy and duraplasty. In this case, progressing quadriparesis resulted from cervical spinal cord compression by thickened dura mater. Earlier surgical decompression could have been better for the patient.
Decompression, Surgical
;
Dermatan Sulfate
;
Dura Mater
;
Female
;
Humans
;
Laminectomy
;
Magnetic Resonance Imaging
;
Mucopolysaccharidoses*
;
Mucopolysaccharidosis I*
;
Quadriplegia
;
Spinal Cord Compression*
;
Spinal Cord*
;
Spine
;
Young Adult
2.Cryptogenic Gelastic Epilepsy of Fronto-Temporal Lobe Origin: A Case of Young Adulthood Onset.
Wook Joo KIM ; Sang Myung CHEON ; Sang Ho KIM
Journal of Korean Epilepsy Society 2002;6(2):154-157
Gelastic epilepsy characterized by paroxysmal involuntary laughing episodes is a relatively rare type of seizure which may occur singly or, more frequently, with other types of convulsions. Gelastic seizures have been observed in many different conditions, mainly hypothalamic hamartomas. We report a 21-year-old woman whose uncontrollable laughter was the only neurologic disturbance since 20 years of age. Physical and neurological examination did not reveal any abnormality. Neuropsychologic test was also normal. Brain magnetic resonance imaging was normal. During video-EEG monitoring, the clinical events usually consisted of aura of undescriable sensation lasting 1-2seconds followed by ictal laughter, without loss of consciousness and postictal manifestation. Ictal EEG showed bilateral interruption of background activity lasting 2-3seconds, followed by semirhythmic theta frequency activities over right frontotemporal region. Interictal EEG showed intermittent sharp waves or spike activities at right anterior temporal area. After Oxcarbamazepine treatment, she has never experienced the laughing seizures.
Brain
;
Electroencephalography
;
Epilepsies, Partial*
;
Epilepsy
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Female
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Hamartoma
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Humans
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Laughter
;
Magnetic Resonance Imaging
;
Neurologic Examination
;
Neuropsychological Tests
;
Seizures
;
Sensation
;
Unconsciousness
;
Young Adult
3.Postoperative Pain Evaluation after Evisceration with Continuous Intravenous Infusion of Butorphanol Using Silicone Balloon Infuser.
Journal of the Korean Ophthalmological Society 2003;44(7):1483-1488
PURPOSE: The analgesic efficacy and side-effects of continuous intravenous infusion of Butorphanol for postoperative pain relief after evisceration were evaluated. METHODS: We evaluated the postoperative pain using Numerical Rating Scale in 19patients undergoing evisceration under general anesthesia. One group (group2, 9patients) received continuous intravenous injection of Butorphanol 14 mg mixed with 5% D/W 100ml using silicone balloon infuser for 2days. The other group (group1, 10patients) was not received it. RESULTS: The second group patients reported less pain compared to the first group patients in the first and second post operative day. The total NRS value of pain was 28.1+/-4.73 (group1) vs 11.22+/-0.99 (group2). CONCLUSIONS: For 48hr post operative pain relief in patients undergoing evisceration, the analgesic efficacy of the continuous intravenous injection of Butorphanol is useful.
Anesthesia, General
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Butorphanol*
;
Humans
;
Infusions, Intravenous*
;
Injections, Intravenous
;
Pain, Postoperative*
;
Silicones*
4.Sleep Disturbances in Patients with Parkinson's Disease according to Disease Severity.
Su Yun LEE ; Sang Myung CHEON ; Jae Woo KIM
Korean Journal of Clinical Neurophysiology 2015;17(1):17-23
BACKGROUND: Sleep-related disturbances and sleep disorders are common in Parkinson's disease (PD) and have a great impact on daily life of PD patients. This study was done to find the sleep characteristics and sleep disturbing factors in PD patients according to disease severity through clinical interview and polysomnographic (PSG) study. METHODS: Fifty patients with PD (22 males, age 60.6 +/- 6.4, Hoehn and Yahr (HY) stage 2.7 +/- 1.0) were recruited and thoroughly interviewed about their sleep. PSG was performed on the patients taking routine antiparkinsonian medications. Patients were grouped into mild and moderate/severe group according to HY stage, and the results were compared between each group. RESULTS: Ninety-four percent of total patients had one or more sleep-related disturbances based on the interview or PSG. On interview, the moderate/severe group complained more insomnia and REM sleep behavior disorder (RBD) than mild group. In PSG findings, the moderate/severe group showed lower sleep efficiency, longer sleep latency, REM sleep latency, waking time after sleep onset, and higher prevalence of RBD. CONCLUSIONS: In this study, most patients with PD had sleep disturbances. Clinical interview and PSG findings revealed deterioration of sleep quality along the disease severity. Our results suggest that sleep disturbances in PD patients are prevalent and warrant clinical attention, especially to the patients with advanced disease.
Humans
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Male
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Parkinson Disease*
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Polysomnography
;
Prevalence
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REM Sleep Behavior Disorder
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Sleep Wake Disorders
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Sleep Initiation and Maintenance Disorders
;
Sleep, REM
5.Spontaneous Cerebral Air Embolism.
Rae Young KIM ; Sang Myung CHEON ; Hyun Wook NAH
Journal of the Korean Neurological Association 2017;35(4):268-269
No abstract available.
Embolism, Air*
6.Abdominal Trauma with Rib Fractures; What is the level of rib fractures we must evaluate intra-abdominal injuries?.
Joon Seok PARK ; Sang Moon PARK ; Seok Cheon HYUN ; Myung Hee KANG ; Kab Deuk KIM ; Wha Shik SONG
Journal of the Korean Society of Emergency Medicine 1997;8(2):228-233
Many authors have been reported that the abdominal trauma, especially injury of the liver and spleen, is frequently found with lower rib fractures, below the ninth rib fractures and the incidence was about 20 to 30%. In cases of rib fractures, Intra- abdominal organs may be injured in the higher rib fractures than the ninth because the diaphragm is elevated at the level of filth intercostal space in expiration period and the intra-abdominal lesions are often delayed evaluated due to the pain of the fractures and masked by the other injuries of the head and the extremities. So above reasons, we were often questioned what the level of rib fracture we must evaluate the intra-abdominal injury was? So we investigated 452 patients with rib fractures who visited our emergency medical center from 1995, January to 1996, December and divided into two groups according to the prescience of intra-abdominal organ injuries by each the level of rib fractures. The number of patients with intra-abdominal organ injuries were 75(16.6%) and the most frequently damaged organ was the liver(25 cases, 33.3%). We calculated the statistical values of each level of rib fractures by the Chi-Square method and got a result that the level of rib fracture we must evaluate the intra-abdominal injuries was the sixth rib fracture. Therefore, if we will meet the patients with rib fracture below the sixth, we must have attentions to the intra-abdominal injuries and evaluate the abdomen closely with various diagnostic methods.
Abdomen
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Attention
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Diaphragm
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Emergencies
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Extremities
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Head
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Humans
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Incidence
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Liver
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Masks
;
Rib Fractures*
;
Ribs*
;
Spleen
7.Three Cases of Hemiparkinsonism-hemiatrophy Syndrome.
Min Jeong PARK ; Sang Myung CHEON ; Jae Woo KIM
Journal of the Korean Neurological Association 2005;23(6):823-826
Hemiparkinsonism with hemiatrophy (HP-HA) syndrome is characterized by a predominant unilateral parkisonism associated with ipsilateral body and/or contralateral brain abnormality. We report three cases of Hemiparkinsonism- hemiatrophy, which is a rare form of secondary parkinsonism. One patient revealed motor complication in the involved limb suggesting that the degeneration of nigrostriatal pathway as the underlying mechanism in this disorder. The functional neuro-imaging can play an important role to verify the cortical abnormalities when structural changes are not evident in brain MRI.
Brain
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Extremities
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Humans
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Magnetic Resonance Imaging
;
Neuroimaging
;
Parkinson Disease, Secondary
;
Parkinsonian Disorders
8.Magnetic Resonance Image Findings of Cerebral Amyloid Angiopathy Related Inflammation
Byeol A YOON ; Kyung Won PARK ; Sang Myung CHEON
Journal of the Korean Neurological Association 2019;37(4):438-439
No abstract available.
Cerebral Amyloid Angiopathy
;
Inflammation
9.Trends in Physiotherapy Interventions and Medical Costs for Parkinson’s Disease in South Korea, 2011–2020
Dong-Woo RYU ; Jinse PARK ; Myung Jun LEE ; Dallah YOO ; Sang-Myung CHEON
Journal of Movement Disorders 2024;17(3):270-281
Objective:
Physiotherapy (PT), which is an effective strategy for managing Parkinson’s disease (PD), can influence health care utilization. We analyzed trends in health care utilization, PT interventions, and medical costs among patients with PD.
Methods:
Using data from the Korean National Health Insurance Service from 2011 to 2020, we analyzed the number of patients with PD and their health care utilization and assessed the odds ratio (OR) for receiving regular PTs.
Results:
Over 10 years, 169,613 patients with PD were included in the analysis. The number of patients with PD increased annually from 49,417 in 2011 to 91,841 in 2020. The number of patients with PD receiving PT increased from 4,847 (9.81%) in 2011 to 13,163 (14.33%) in 2020, and the number of PT prescriptions increased from 81,220 in 2011 to 377,651 in 2019. Medical costs per patient with PD increased from 1,686 United States dollars (USD) in 2011 to 3,202 USD in 2020. The medical expenses for each patient with PD receiving PT increased from 6,582 USD in 2011 to 13,475 USD in 2020. Moreover, regular PTs were administered to 31,782 patients (18.74%) and were administered only through hospitalization. Those patients in their 50s with disabilities demonstrated a high OR for regular PTs, whereas those aged 80 years or older and residing outside of Seoul had a low OR.
Conclusion
The PD burden increased in South Korea between 2011 and 2020, as did health care utilization and medical costs. A significant increase in medical expenses can be associated with increased PD incidence and PT interventions. Regular PT applications remain restricted and have barriers to access.
10.Dementia with Lewy Bodies versus Alzheimer's Disease and Parkinson's Disease Dementia: A Comparison of Cognitive Profiles.
Kyung Won PARK ; Hyun Sook KIM ; Sang Myung CHEON ; Jae Kwan CHA ; Sang Ho KIM ; Jae Woo KIM
Journal of Clinical Neurology 2011;7(1):19-24
BACKGROUND AND PURPOSE: It is particularly difficult to differentiate dementia with Lewy bodies (DLB) from the related dementias of Alzheimer's disease (AD) and Parkinson's disease dementia (PDD). Few studies have been designed to comparatively analyze detailed neuropsychological assessments of DLB patients and patients with AD and PDD. METHODS: Three groups of patients participated in this study: 10 with DLB, 76 with AD, and 17 with PDD, who had been diagnosed as probable DLB, AD, and PDD, respectively, according to the clinical criteria of the consortium on DLB, National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer's Disease and Related Disorder Association, and the clinical diagnostic criteria for PDD. All patients were evaluated by careful neurological examination with detailed neuropsychological testing. RESULTS: Significant differences among the three groups were found for attention, memory, and executive function, which included tasks of backward digit span, three-word recall, verbal delayed recall, and the Stroop test. Post hoc analysis revealed that the deficiencies of attention on the digit span task were greater in the DLB group than in the AD and PDD groups. The scores for episodic verbal memory tasks were significantly lower in the DLB and AD groups than in the PDD group. The performance in frontal executive function, as indicated by the Stroop test, was significantly worse in the DLB and PDD groups than in the AD group. CONCLUSIONS: The results of the present study show that the pattern of cognitive dysfunction, in terms of attention, episodic memory, and executive functions, differ between patients with DLB and patients with AD and PDD.
Alzheimer Disease
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Cognition
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Dementia
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Executive Function
;
Humans
;
Lewy Bodies
;
Memory
;
Memory, Episodic
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Neurologic Examination
;
Neuropsychology
;
Parkinson Disease
;
Stroop Test