No abstract available.

Clear cell sarcoma of tendon and aponeurosis is a rare malignant tumor. It occurs chiefly in young adults, predominates in women and is most common in the regions of the foot and ankle. We report a case of clear cell sarcoma of tendon and aponeurosis in s 22-year-old man. he pstient had had a asymptomatic, normal skin colored, relativerly hard, dome shsped nodule on the anterior chest for 6 months. Histopsthologic findings revealed uniform pattern composed of compact nests of round or fusiform cells which had clear cytoplasm and were surrounded by delicate framework of fibrocollagenous tissue, and the individual tumor cell had a fairly regular appearance of possessing round to avoid vesicular nucleus with prominent basophilic nucleolus. One year after surgical excision and post operative radiotherapy, there was no recurrence.
Ankle ; Basophils ; Cytoplasm ; Female ; Foot ; Humans ; Radiotherapy ; Recurrence ; Sarcoma, Clear Cell* ; Skin ; Tendons ; Thorax* ; Young Adult

In vivo 31P NMR spectroscopic study of forearm wrist flexor muscles was performed in two groups of volunteers composed respectively of 6 sedentaries and 6 canoe athletes. A continuous isometric contraction of endurance exercises was adopted in oder to assess the endurance capacity and recovery potential of skeletal muscles. Differences in high energy phosphorus metabolism between the sedentaries and athletes were evaluated with and emphasis on the intracellular pH and Pi/PCr ratio as indicators of high energy phosphorus metabolism. There were no differences of baseline pH and Pi/PCr ratio between the two groups. The athletes sustained the exercise at more acidic intracellular pH and at a higher Pi/PCr ratio of intracellular conditions for an all-out than did the sedentaries. The recovery rate of pH showed no difference between the two groups. There was a tendency of faster recovery of Pi/PCr in athletes showing half recovery time(T1/2) of 39.0±3.0 seconds as compared to that of sedentaries (55.7±7.5 seconds). The recovery rate of Pi/PCr as a function of Pi/PCr ratio at a given period of time was significantly faster in athletes than in sedentaries (P<0.001). The correlation coefficient of the recovery rate of Pi/PCr against the Pi/PCr ratio was 0.985 and 0.914 respectively for the athletes and sedentaries. The pH and the Pi/PCR ratio at an all-out state can be used as indicators of endurance capacity and the recovery rate of Pi/PCr, as a reovery potential of skeletal muscles.
Athletes* ; Exercise ; Forearm ; Humans ; Hydrogen-Ion Concentration ; In Vitro Techniques* ; Isometric Contraction ; Metabolism ; Muscle, Skeletal* ; Muscles ; Phosphorus ; Volunteers ; Wrist

PURPOSE: To describe long-term clinical results and serial changes in the postoperative range of motion (ROM) after arthroscopic treatment for a limitation of motion (LOM) of the elbow. MATERIALS AND METHODS: Sixty-three patients with LOM of the elbow were treated with arthroscopic procedures. The follow-up period averaged 42.5 months. RESULTS: The total ROM was 79.3degrees C preoperatively. From the first and second week after the operation, the ROM showed a progressive increase up to six months postoperatively (mean 109.2degrees C at 3 months and mean 118.4degrees C at 6 months follow-up). Then the ROM continued to increase slowly for a total of 1 year after the operation (mean 121.5degrees C). However, after one year postoperative, the ROM showed little further increase. The ROM acquired during surgery (mean 121.9degrees C) was usually the same range achieved by patients during the rehabilitation period (mean 122.8degrees C at an average of 42.5 months follow-up). Patients with post-traumatic stiffness had more severe flexion contracture and decreased total ROM (73.1degrees C) than those with degenerative stiffness (85.7degrees C) preoperatively. But no significant difference existed in the postoperative total ROM (post-traumatic stiffness, 122.8degrees C and degenerative stiffness, 120.5degrees C). CONCLUSION: Based on our experience, 94% of the patients obtained functional ROM after arthroscopic procedures. The minimally invasive nature of elbow arthroscopy is a safe, reproducible and effective procedure for LOM of the elbow with minimal morbidity.
Arthroscopy ; Contracture ; Elbow Joint* ; Elbow* ; Follow-Up Studies ; Humans ; Range of Motion, Articular ; Rehabilitation

OBJECT: The Composite Scale by Smith et al. has been proposed as an improved measure of momingness-eveningness. This study attempted to endorse that a Korean translation of Composite Scale(KtCS) can be useful to differentiate people according to circadianrhythm types. METHOD: KtCS and Life Habit Questionnaire(LHQ) were administered to 561 university students. LHQ consisted of items questioning sleep habits on weekdays(bedtime, rising time and sleep length), the time of perceived peak alertness(mental and physical), time of perceived peak performance(mental, physical and academic), and quality of academic performance during the morning, afternoon and evening. Subjects were categorized on the basis of their KtCS scores into evening(I) types, intermediate(I) types, and morning(M) types. The cut-off points for these categories were set at the 10th and 90th percentiles. In addition 7 I-type and 7 M-type subjects were selected from the student population who had participated in the previous survey and then, oral temperature of each subject was taken every hour torn 08 : 00 to 22 : 00. To assess both the internal and the external measurement properties of KtCS, descriptive statistics, reliability and validity were examined. RESULTS: The distribution of KtCS scores was significantly, negatively skewed. The KtCS scores closest to the 10th and 90th percentiles were 26 and 41 respectively. The split-half reliability(. 85), test-retest reliability( .91), and internal consistency(Cronbach alpha, .82) were obtained above the expected. Inter-item correlations were all positive and ranged from .10-.59 with a mean of .25. Item-total correlations varied from .33 to .63 with a mean of .45. Common factor analyses confirmed three factors: preferred times of performance and going to bed, arising time, and morning alertness. The validity of KtCS was further demonstrated through strong relationships between the scale and external criteria.4 discernable difference in oral temperature between the M-type and the type across morning to evening provided additional evidence for validity of the scale. CONCLUSIONS: The results would suggest the possibility that KtCS can be employed as a tool for selection of I-type people or M-type people. It is as yet, however, uncertain that KtCS might be suitable to select people for night shiftwork because the subjects of this study are limited to university students. Therefore, future research among varying types of people are required to endorse this study.
Humans ; Reproducibility of Results

BACKGROUND: Cisplatin (CP), an antitumor agent widely used in the treatment of cancers, has nephrotoxicity. This side effect is closely related to oxidative stress. In the present study, we attempted to reduce CP-induced nephrotoxicity in rats by administering melatonin, an antioxidant. METHODS: Male Sprague-Dawley rats were divided into different groups and were treated as follows: (1) saline control; (2) CP (16 mg/kg, i.p.); (3) CP plus melatonin (10 mg/kg, i.p.). The rats were sacrificed at the 6th day after CP treatment. To evaluate renal damage, BUN, serum creatinine, creatinine clearance and microscopic examination were done. Hydrogen peroxide which is one of the oxygen free radicals, and malondialdehyde which is known as a marker of the oxygen free radical mediated injury, and the activities of the antioxidant enzymes such as superoxied dismutase, catalase, and glutathione peroxidase were also measured. RESULTS: CP-treated rats showed the increase of BUN, serum creatinine, malondialdehyde, hydrogen peroxide and superoxide dismutase (SOD) in kidney. And CP-treated rats also showed the decrease of creatinine clearance and catalase levels. CP-treated rats showed severe tubular necrosis in proximal convoluted tubules under the light microscopic examination. The light microscopic finding and all of the parameters except SOD were restored in the rats injected with CP plus melatonin than those with CP alone. SOD level was higher in the rats injected with CP plus melatonin than that with CP alone. CONCIUSION: These results suggest that melatonin suppresses CP-induced nephrotoxicity by suppressing the production of reactive oxygen species via the activation of SOD and catalase.
Animals ; Catalase ; Cisplatin* ; Creatinine ; Free Radicals ; Glutathione Peroxidase ; Humans ; Hydrogen Peroxide ; Kidney ; Male ; Malondialdehyde ; Melatonin* ; Necrosis ; Oxidative Stress ; Oxygen ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species ; Superoxide Dismutase

Miliary tuberculosis is a severe form of tuberculosis resulting from dissemination of Mycobacterium tuberculosis bacilli. Since symptoms appearing in patients due to miliary TB are diverse and atypical, depending on the site of invasion, early diagnosis and treatment are important. A paradoxical response of tuberculosis is a rare phenomenon and it can be a clinical difficulty to treatment especially when involving the central nervous system. We present a case report with a review of related literature about the patient who developed sudden hearing loss due to tuberculosis infection in vestibulocochlear area.
Central Nervous System ; Early Diagnosis ; Hearing Loss, Sensorineural ; Hearing Loss, Sudden ; Humans ; Mycobacterium tuberculosis ; Tuberculosis ; Tuberculosis, Miliary

OBJECTIVE: This study aimed to comprehensively evaluate psychosocial risk factors associated with suicidality in patients with schizophrenia in Korea. METHODS: The study sample consisted of 84 hospitalized patients with schizophrenia. Suicidal thoughts and a clear desire to be dead within 2 weeks were defined as a current suicidal ideation. Socio-demographic and clinical variables, including family history of completed suicides and psychiatric illnesses, were collected, and the Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schizophrenia (CDSS), Beck Depression Inventory (BDI), Simpson-Angus Scale (SAS), Scale to assess Unawareness of Mental Disorder (SUMD), and Alcohol Use Disorders Identification Test (AUDIT) were administered to identify factors associated with a current suicidal ideation. RESULTS: Forty-three subjects (51.2%) reported clear suicidal ideation. Multivariate analysis revealed that later age of illness onset, previous suicide attempt, family history of completed suicide, depression, or substance abuse, fewer than one family visitation to the hospital per month, and score on the CDSS were independently related to current suicidal ideation in these subjects. Age, education level, and scores on the SUMD were not significantly associated with current suicidal ideation in the multivariate analysis, but were associated with suicidal ideation in a univariate analysis on the level of p<0.1. CONCLUSION: The above clinical factors should be evaluated to predict and prevent suicidal risk in patients with schizophrenia. In particular, modifiable factors such as depression should be managed to reduce suicidality of hospitalized patients with schizophrenia.
Depression ; Humans ; Korea ; Mental Disorders ; Multivariate Analysis ; Risk Factors ; Schizophrenia ; Substance-Related Disorders ; Suicidal Ideation ; Suicide

PURPOSE: Use of a home mechanical ventilator can shorten the hospitalization duration of children with chronic respiratory failure requiring long-term use of a mechanical ventilator. In this study, the researchers analyzed patients who had used a home mechanical ventilator. METHODS: From January 2009 to July 2014, we retrospectively investigated 15 patients under 18 years of age, from 2 hospitals, and their use of home mechanical ventilators. RESULTS: The median age of the patients was 55 months. Ten children were male, and 5 were female. As for the type of mechanical ventilators, 10 used a pressure type, 3 used a volume type, and 2 used a volume-mask type. Analysis of underlying diseases revealed that 10 children had neuromuscular disease, 3 had pulmonary disease, and 2 suffered from hypoxic ischemic encephalopathy. The number of patients who were discharged from the hospital with a home mechanical ventilator was 13. One child died of sepsis irrespective of the mechanical ventilator. Six patients had health insurance. But 9 did not. The group with insurance had the possibility of being discharged earlier than the group without. On readmission, the length of hospitalization was also reduced in patients who had used a home mechanical ventilator. CONCLUSION: Use of a mechanical ventilator at home is helpful in patients who need long-term use of a mechanical ventilator due to neuromuscular disease, chronic pulmonary diseases, and accidents because complications are rare and insurance coverage is feasible.
Child ; Female ; Hospitalization ; Humans ; Hypoxia-Ischemia, Brain ; Insurance Coverage ; Insurance* ; Insurance, Health ; Lung Diseases ; Male ; Neuromuscular Diseases ; Respiratory Insufficiency ; Retrospective Studies ; Sepsis ; Ventilators, Mechanical*

Tubo-ovarian abscess is an end-stage disease of acute pelvic inflammatory disease (PID). Since most cases of PID are caused by sexually transmitted microorganisms, this is very rare in children. Here, we report an 1 1/2-year-old girl with bilateral tubo-ovarian abscesses. She was admitted to our Department with chief complaints of fever, vomiting and diarrhea. Abdominal ultrasonography and CT scanning of the patient showed solid and cystic masses in pelvic cavity. It was very difficult to differentiate the lesions from abscess and tumor. In addition, intravenous pyelography (IVP) and abdominal CT scanning of the patient showed both hydronephrosis and ureteral dilatation. Because of severe visceral adhesions, we could not perform laparoscopic examination of the pelvic masses. By exploratory operation and frozen biopsy, the masses were confirmed as tubo-ovarian abscesses and they were drained. In the bacterial culture, K. pneumoniae and E. coli were grown. The patient was treated with sensitive antibiotics and recovered from her disease. After 4 weeks of operation, IVP showed no abnormal findings and voiding cystourethrography (VCUG) showed grade I vesicoureteral reflux of the left side. It was suggested the hydronephroses were developed by the ureteral obstruction of tubo-ovarian abscesses.
Abscess* ; Anti-Bacterial Agents ; Biopsy ; Child ; Diarrhea ; Dilatation ; Female* ; Fever ; Glycogen Storage Disease Type VI ; Humans ; Hydronephrosis ; Pelvic Inflammatory Disease ; Pneumonia ; Tomography, X-Ray Computed ; Ultrasonography ; Ureter ; Ureteral Obstruction ; Urography ; Vesico-Ureteral Reflux ; Vomiting