No abstract available.
Temporomandibular Joint*

In the following report, we describe the case of a rapidly skeletonized corpse discovered in late summer. On the first day of September, a 57-year-old man was found almost completely skeletonized on a hill behind his house. His body lay prone, accompanied by a brush cutter at the entrance to the graveyard where his friend's parents were buried. His cap, clothes, and rubber boots were all intact and undamaged. Upon autopsy, no definite abnormalities were identified except for an old linear fracture on the frontoparietal bone. According to his friends and neighbors, he had likely died 8 or 9 days prior to the discovery of his body.
Autopsy ; Cadaver ; Friends ; Humans ; Middle Aged ; Parents ; Postmortem Changes ; Rubber ; Skeleton*

No abstract available.
Giant Cells ; Gingiva ; Granuloma, Giant Cell ; Osteomalacia

To establish predictors of prognosis and recurrence of hepatocellular carcinoma (HCC) after curative resection, retrospective analyses of clinical and pathologic factors were done in 85 hepatectomized patients of HCC. The median follow-up duration was 30.5(range: 3-134) months. Two postoperative mortalities and five palliative resections were excluded from analysis of recurrence. The overall 1, 3, 5 year survival rates in 85 patients were 78.6%, 63.6%, 45.6%. The 1, 3, 5 year survival rates in 78 curative resections were 81.8%, 70.2%, 50.3%. The 1, 2, 3 year survival rates of the palliative resections(5 cases) were 60%, 20%, 0%. The 1, 3, 5 year recurrence-free survival rates in the curative resections were 64.4%, 43.2%, 27.5%. Included prognostic variables were age, gender, viral hepatitis, cirrhosis, serum alpha-FP level, ICG-R15, diabetes, preoperativeTACE, tumor size, tumor capsulation, number of tumors, vascular invasion, tumor histologic grading, stage of the chronic hepatitis, and anatomic resection. The significant factors affecting recurrence were number of tumors and vascular invasion.
Carcinoma, Hepatocellular* ; Fibrosis ; Follow-Up Studies ; Hepatectomy ; Hepatitis ; Hepatitis, Chronic ; Humans ; Mortality ; Prognosis ; Recurrence* ; Retrospective Studies ; Survival Rate

No abstract available.

No abstract available.
Graves Disease* ; Insulin*

We report a case of spinal subdural abscess spreading from a epidural abscess. A 70-year-old man was hospitalized for a mild fever, chill and severe back pain. Neurological examination on admission revealed back pain with numbness, sensory deficiency on left lower extremity and without bowel or bladder dysfunction. Lumbar magnetic resonance imaging(MRI) showed pyogenic spondylitis on L1, 2, 3 with epidural abscess. A patient was treated by empiric antibiotic therapy for 6 weeks. Six weeks later, follow-up MRI showed that the pyogenic spondylitis with epidural abscess had decreased, but a cylinder like subdural abscess after arachnoiditis. After surgery, the majority of the initial symptoms were relieved except a mild both lower extremities numbness.
Abscess* ; Aged ; Arachnoid ; Arachnoiditis ; Back Pain ; Epidural Abscess* ; Fever ; Follow-Up Studies ; Humans ; Hypesthesia ; Lower Extremity ; Magnetic Resonance Imaging ; Neurologic Examination ; Spondylitis ; Urinary Bladder

The role of the periosteum on osteointegration of Bio-Oss(R)(Geistlich, Wolhusen/Switzerland) was studied in rabbit calvarial defect. 12 New Zealand white male rabbits between 2.8 and 4 kg were included in this randomized, blinded, prospective study. Each rabbit was anesthetized with Ketamine HCl(5 mg/kg) and Xylazine HCl(1.5 ml/kg). An incision was made to the bony cranium and the periosteum was reflected. Using a 6-mm trephine bur(3i. USA), four 8-mm defects were created with copious irrigation. The defects were classified into barrier membrane(Tefgen(R), Lifecore Biomedical, Inc, U.S.A.) only group as a control, Bio-Oss(R) with barrier membrane group, Bio-Oss(R) with periosteum covering group, and Bio-Oss(R) without periosteum covering group. There were 2 rabbits in each group. The wound was closed with resorbable suture materials. Rabbits were sacrificed using phentobarbital(100 mg/kg) intravenously at 1, 2, and 4 weeks after surgery. The samples were fixed in 4% paraformaldehyde, and decalcified in hydrochloric acid decalcifying solution(Fisher Scientific, Tustin, CA) at 4degrees C for 2-4 weeks. It was embedded in paraffin and cut into 6 micrometer thickness. The sections were stained with H & E and observed by optical microscope. The results were as follows; 1. The periosteum played an important role in osteointegration of Bio-Oss(R) in bone defects. 2. When the periosteum remained intact and Bio-Oss(R) was placed on the defect, Bio-Oss(R) with periosteum covering has been incorporated into the newly formed bone from 2-week postoperatively. 3. When the periosteum was removed at the surgical procedure, invasion of connective tissue took place among the granules, and new bone formation was delayed compared to periosteum covering group. Therefore, when the bone grafting was performed with periosteal incision procedure to achieve tension-free suture, the integrity of the overlying periosteum should be maintained to avoid fibrous tissue ingrowth.
Bone Regeneration* ; Bone Transplantation ; Connective Tissue ; Humans ; Hydrochloric Acid ; Ketamine ; Male ; Membranes ; New Zealand ; Osteogenesis ; Paraffin ; Periosteum* ; Prospective Studies ; Rabbits ; Skull ; Sutures ; Wounds and Injuries ; Xylazine

No abstract available.
Adenoma, Pleomorphic ; Mouth Mucosa

"It was reported that polymorphism of TNF alpha gene was present in promoter region and involves the substitution of guanine by adenosine in the uncommon (TNFA 2) allele. In this study, we investigated the significance of TNFA gene polymorphism in relation to various clinical characteristics and autoantibody profiles in SLE as well as comparing it with that of other countries, and also studied its association with peripheral TNF-a production in vitro. TNFA genotyping was performed in 126 SLE patients and 300 controls using DNA extracted from peripheral leucocytes. The biallelic polymorphism at position -308 of the TNFA promotor was determined by Ncol- RFLP. Peripheral mononuclear cell production of TNF-a was investigated by bioassay using L-929 cell cytotoxicity. The TNFA ""1 homozygote was a predominant allele (77.0%) in SLE, which was not different from the controls. TNFA ""2 homozygate was extremely rare in both patients and controls (0.8%, 1.3% respectively). The clinical manifestations between TNFA '1 and TNFA""2 did not differ. The production of autoantibodies including dsDNA, anti-La, anti-nRNP and anti-Sm was not different between two alleles, whereas anti- Ro antibody was more frequent in TNFA""1/TNFA '1 than in TNFA'1/TNFA'2 (62.1% vs 38.4%, P=0.022). The polymorphism of TNFA gene did not influence the lipopolysaccharide stimulated peripheral mononuclear cell production of TNF-a (1356+/-293 vs 1119+/-385 pg/ml; TNFA'1/TNFA'1, TNFA'1/TNFA'2 respectively). These results suggested that promoter polymorphism of TNFA was not directly involved in the susceptibility of SLE and was not responsible for differential peripheral TNF-a production, but TNFA ' may be associated with anti-Ro antibody production."
Adenosine ; Alleles ; Autoantibodies ; Biological Assay ; DNA ; Guanine ; Homozygote ; Humans ; Lupus Erythematosus, Systemic* ; Polymorphism, Restriction Fragment Length ; Promoter Regions, Genetic ; Tumor Necrosis Factor-alpha*