1.Comparison of Diagnostic and Post-therapy Radioiodine Scan in Well-Differentiated Thyroid Cancer and the Clinical Outcome.
Seok Mo LEE ; Sang Kyun BAE ; Ha Yong YUM
Korean Journal of Nuclear Medicine 2000;34(1):22-29
PURPOSE: We compared the first postoperative diagnostic and post-therapy scans of patients who received therapeutic doses of I-131, to investigate the difference in clinical outcomes between patients with concordant findings of diagnostic and post-therapy scans and patients with discrepant (more lesions in post-therapy scan) findings. MATERIALS AND METHODS: The first postoperative diagnostic and post-therapy radioiodine scans of one hundred forty three patients with well differentiated thyroid carcinoma were reviewed. Diagnostic scans were obtained following ingestion of 185 MBq of I-131 and post-therapy scans were obtained after therapeutic dose of 3.7~9.3 GBq of I-131. Successful ablation was defined as no radioiodine uptake on diagnostic radioiodine scan and normal range of serum thyroglobulin level (<10 ng/ml) during serum TSH elevation. RESULTS: Discrepant scan findings were noted in 25 (17.5%) patients. Twenty-two patients (15.4%) showed more lesions in post-therapy scan and 3 patients (2.1%) showed stunning effect. Nine (64.3%) of 14 patients with distant metastasis revealed metastatic lesion(s) only on post-therapy scan. Stunning effect was considered as sublethal damage in 1 patient and treatment by a diagnostic dose in 2 patients. Ablation was achieved in 52.4% (75/143) of all patients. Ablation rate and mean cumulative radioiodine dose were not different statistically between concordant and discrepant groups. CONCLUSION: There were 17.5% difference between diagnostic and post-therapy scan findings when using 185 MBq of I-131 as a diagnostic dose. However, 64.3% of distant metastases were revealed only on post-therapy scan. Ablation rate and mean cumulative radioiodine dose were not different statistically between concordant and discrepant groups. The stunning effect was considered as not only sublethal damage but also treatment by a small diagnostic dose of radioiodine.
Eating
;
Humans
;
Neoplasm Metastasis
;
Reference Values
;
Thyroglobulin
;
Thyroid Gland*
;
Thyroid Neoplasms*
2.Acute Osteomyelitis Shown as a Cold Lesion on Bone Scan.
Suk Mo LEE ; Sang Gyun BAE ; Myung Rae JO
Korean Journal of Nuclear Medicine 2000;34(6):516-520
Acute osteomyelitis is usually shown as a localized area of increased activity (hot uptake) in the infectious focus on bone scintigraphy. In our patient, absence of radioactivity (cold lesion) was noted in the distal metaphyseal and diaphyseal regions of his right femur. Initial x-ray was interpreted as normal except for mild soft tissue swelling in the right thigh. The lesion was confirmed as an acute osteomyelitis with subperiosteal abscess on surgery. Staphylococcus aureus was the etiologic organism. We describe a case of acute osteomyelitis in a one-year-old boy shown as a cold lesion on bone scan.
Abscess
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Femur
;
Humans
;
Male
;
Osteomyelitis*
;
Radioactivity
;
Radionuclide Imaging
;
Staphylococcus aureus
;
Technetium Tc 99m Medronate
;
Thigh
3.Anteroposterior Diameters of Lower Lumbar Discs in the Koreans.
Hwan Mo LEE ; Nam Hyun KIM ; Sang Jin SHIN
Journal of Korean Society of Spine Surgery 1997;4(1):11-17
No abstract available.
4.Cysticercosis of the Spine
Kyu Sung LEE ; Myung Sang MOON ; Hyoun Mo YOON
The Journal of the Korean Orthopaedic Association 1984;19(5):990-992
Cysticercosis which very rarly involves spinal canal, may show symptoms similar to herniated nucleus pulposus and cord tumor, and even myelogram may not be helpful for the accurate diagnosis. In this paper, a case in which free floating larvae of taenia solium mimicking intradural tumor by myelogram and clinical symptoms were presented. The present authors feel that cysitcercosis has to be considered as a cause when there is central filling defect of contrast media in myelogram.
Contrast Media
;
Cysticercosis
;
Diagnosis
;
Larva
;
Spinal Canal
;
Spine
;
Taenia solium
5.An analysis of contents of inpatient in department of family medicine.
Hyun Ja KIM ; Young Ran LEE ; Go Bong LEE ; Bung Chul LEE ; Sang Mo CHOI
Journal of the Korean Academy of Family Medicine 1991;12(9):18-23
No abstract available.
Humans
;
Inpatients*
6.A study on the relationship between family APGAR and cigarette smoking.
Young Ran LEE ; Hyun Ja KIM ; Go Bong LEE ; Byung Chul LEE ; Sang Mo CHOI
Journal of the Korean Academy of Family Medicine 1991;12(5):38-45
No abstract available.
Humans
;
Smoking*
;
Tobacco Products*
7.The influence of family factors on drinking behavior of university students.
Byung Chul LEE ; Hyun Ja KIM ; Ko bong LEE ; Young Ran LEE ; Sang Mo CHOI
Journal of the Korean Academy of Family Medicine 1991;12(10):51-60
No abstract available.
Drinking Behavior*
;
Drinking*
;
Humans
8.MR Imaging of the Pigmented Villonodular Synovitis of the Knee.
Sang Hoon LEE ; Joong Mo AHN ; Heung Sik KANG ; Chu Wan KIM ; Han Koo LEE
Journal of the Korean Radiological Society 1994;31(1):165-170
PURPOSE: To describe the magnetic resonance (MR) findings of pigmented villonodular synovitis(PVNS) of the knee, and to evaluate the clinical value of MR in the diagnosis of PVNS. MATERIALS AND METHODS:MR imagings of seven patients with PVNS were studied. The type of lesion, presence of bony erosion, the signal intensity, and the relationship between contrast enhancement and signal intensity on T2-weighted images were analyzed, retrospectively. RESULTS: The lesion was mainly villous in three patients and nodular in four, and bony erosion was seen in one patient. On T2-weighted image, the signal intensity of the villous form was mixed iso- and hypointense in two, hypointense in one, and that of the nodular form was heterogeneous with hypo-, iso-, and hyperintensities. The hypointense portion on T2-weighted image showed poor contrast enhancement, which may suggest hemosiderin deposition or advanced fibrosis. The iso- or hyperintense portion on T2-weighted image showed strong enhancement, which suggest active cellular proliferation. CONCLUSION:MR imaging could be a very useful modality in the diagnosis as well as prediction of histological findings of the PVNS.
Cell Proliferation
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Diagnosis
;
Fibrosis
;
Hemosiderin
;
Humans
;
Knee*
;
Magnetic Resonance Imaging*
;
Retrospective Studies
;
Synovitis, Pigmented Villonodular*
9.A study of perception for family medicine & health promotion.
Go Bong LEE ; Young Ran LEE ; Hyun Ja KIM ; Sang Mo CHOI
Journal of the Korean Academy of Family Medicine 1991;12(8):38-49
No abstract available.
Health Promotion*
;
Humans
10.A Case of Inherited Thymic Dysplasia Associated with Disseminated Cytomegalovirus Infection.
Seung Yeon NAM ; Mee Ae KANG ; Kang Mo AHN ; Young Jae KOH ; Sang Il LEE
Pediatric Allergy and Respiratory Disease 2000;10(2):171-176
No abstract available.
Cytomegalovirus Infections*
;
Cytomegalovirus*