1.KCNJ11 gene mutation in 3 cases with neonatal diabetes mellitus
Yanmei SANG ; Guichen NI ; Yi GU ; Min LIU
Chinese Journal of Endocrinology and Metabolism 2010;26(8):682-683
KCNJ11 gene mutation was searched in 3 families with neonatal diabetes. A KCNJ11 175 G>A (V59M) mutation was found in one child, while no KCNJ11 gene mutation was found in his parents. No mutation was found in the other two families. The result indicated that KCNJ11 gene mutation might lead to the onset of neonatal diabetes mellitus in Chinese.
2.Treatment of Bone and Tendon-Exposed wounds using-Terudermis.
Min Ho CHOI ; Sang Bok YI ; Jung Wook HWANG ; Wan Suk YANG ; Kang Kill LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(3):491-497
Deep skin and soft tissue defects with exposed bone and tendon is difficult to treat, because skin graft rarely survives and flap surgery is sacrifice of donor site. Since "Stage I" membrane was developed by Yannas and Bruke in 1980, numerous kinds of artificial skin have been developed. The adaptability of "Terudermis", developed by the Terumo Co., as an artificial skin composed of sponge made of a fibrillar atelocollagen and a heat-denatured atelocollagen, was clinically evaluated on application to 13 cases presenting deep skin and soft tissue defect with exposed bones and tendons from October 1997 to march 1998. Terudermis has the advantage of allowing early incorporation of fibroblasts and capillaries into its collagen sponge due to very weak dehydrothermal cross-linking. Before Terudermis graft, several days of wet dressing and debridement were required to prepare healthy well-vascularized bed because Terudermis was weak on unsanitary wounds. After bed preparation, Terudermis was grafted like usual skin graft. Tie-over bolster dressing or compressive dressing was used case by case. The dressing was opened 2~3 days after Terudermis grafting. Wet dressing was done daily until the skin graft was done. Autologous skin graft was done 2-3 weeks after Terudermis graft. Our clinical results indicated that Terudermis was beneficial in treating 77% of our patients. Through the use of this new method, treatment of severe skin and soft tissue defects that are usually treated by musculocutaneous or other conventional skin flaps can be replaced by Terudermis as an new artificial dermis.
Bandages
;
Capillaries
;
Collagen
;
Debridement
;
Dermis
;
Fibroblasts
;
Humans
;
Membranes
;
Porifera
;
Skin
;
Skin, Artificial
;
Tendons
;
Tissue Donors
;
Transplants
;
Wounds and Injuries*
3.The Concepts Change of Exercise Intensity for Obesity.
Journal of Metabolic and Bariatric Surgery 2016;5(1):11-17
As being obesity is associated with numerous health problems, effective fat loss strategies are required. Although dieting has been the major fat loss method, aerobic exercise programs have been shown to increase cardiorespiratory fitness and preserve fat-free mass. Most aerobic exercise interventions have consisted of moderate-intensity steady-state exercise. Disappointingly, these kinds of exercise programs have resulted in minimal fat loss. In contrast, high-intensity intermittent exercise (HIIE) has been shown to result in greater fat loss. Accumulating evidence suggests that high intensity intermittent exercise (HIIE) has the potential to be an economical and effective exercise protocol for reducing fat of overweight individuals, especially Tabata workout and Crossfit.
Diet
;
Exercise
;
Methods
;
Obesity*
;
Overweight
4.The Effectiveness of Lowdose Gonadotropin-Releasing Hormone Agonist and high dose hMG after Estrogen-Progesterone therapy in poor responder group to ovarian hyperstimulation.
Sang Hoon YI ; Min HUR ; Yeon hee KIM ; Dong ho KIM ; Do hwan BAE
Korean Journal of Obstetrics and Gynecology 2000;43(1):76-81
OBJECTIVE: To evaluate the efficacy of low dose gonadotropin releasing hormone agonist(GnRH-a) therapy combined with high dose human menopausal gonadotrpin(hMG) following estrogen & progesteron therapy for poor responders. METHODS: From May 1997 to Feb 1999, 36 patients who were defined as poor responders on previous consecutive two and more superovulation cycles were randomly allocated to lowdose GnRH-a short protocol with high dose hMG protocol pretreated with estrogen & progesterone(E/P therapy)(n=16)(study group) and the clomiphene citrate with hMG(n=20)(control group). All patients were planned to undergone in-vitro- fertilization(IVF) and embryo transfer(ET) after controlled ovarian hyperstimulation(COH). RESULTS: Two groups were similar with respect to clinical features and basal FSH and E2 levels. The mean level of E2 on day 5, 304.3+/-148.ng/ml in study group was significantly higher than that in control group, 182+/-34.9ng/ml. The mean levels of E2 on hCG day was also significantly higher in study group than control group(1324+/-320ng/ml, vs 414+/-168ng/ml). The mean day of hCG day in study group, 12.3+/-0.3 was shorter than that in control group, 13.8+/-0.4. The concellation rates of cycles were significantly lower in study group than control group(13.2% vs 84.2%). But clinical pregnancy rates did not showed the significant difference between two groups. CONCLUSION: The study suggested that a lowdose GnRH-a short protocol with high dose hMG pretreated with estrogen & progesterone can improve the ovarian response in poor responder group.
Clomiphene
;
Embryonic Structures
;
Estrogens
;
Gonadotropin-Releasing Hormone*
;
Humans
;
Pregnancy Rate
;
Progesterone
;
Superovulation
5.Studies on the Inulinase Protective Agent of the Aspergillus niger U?-2
Yan-Zhong ZHU ; Ying-Min JIA ; Hong-Wei YU ; Ya-Xin SANG ; Yi-Ling TIAN ;
Microbiology 1992;0(05):-
The thermostability of the inulinase was studied in this resea rc h. Some alcoholic materials and thickening agent could enhance the thermostabli lity of the inulinase. Using glycerol、xanthic pastern and though orthogonal ex periments of three elements and three levels, a satisfying protective agent, whi ch included glycerin(6%), xanthan gum(0.6%) and CaCl_2 (100mmol/mL) and ha d a significant effect on the enhancement of the inulinase thermostability, was acquired.
6.Ameloblastic fibro-odontoma(AFO) in the maxilla: a case report.
Hyen Min KIM ; Jun Kyu YI ; Cheol Hyun MOON ; Sang Min YI
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2006;32(6):594-597
Ameloblastic fibro-odontoma(AFO) is a rare mixed odontogenic tumor. It is composed of connective tissue characteristic of an ameloblastic fibroma and calcified tissue as a complex or compound odontoma. AFO usually presents itself as an asymptomatic swelling of jaw or failure of tooth eruption. The lesion usually occurs in individual less than 30 years old. The differential diagnosis of this tumor includes odontoma, ameloblastoma, and ameloblastic fibroma. This report describes an ameloblastic fibro-odontoma occurring in maxilla of sixteen-year-old female. The lesion was treated by surgical enucleation and curettage without extraction of the involved canine(#23). This patient has shown no sign of recurrence during postoperative 34 months. So we report our case with review of literatures.
Adult
;
Ameloblastoma
;
Ameloblasts*
;
Connective Tissue
;
Curettage
;
Diagnosis, Differential
;
Female
;
Fibroma
;
Humans
;
Jaw
;
Maxilla*
;
Odontogenic Tumors
;
Odontoma
;
Recurrence
;
Tooth Eruption
7.Symptomatic Growth of a Thrombosed Persistent Sciatic Artery Aneurysm after Bypass and Distal Exclusion.
Song Yi KIM ; Sungsin CHO ; Min Ji CHO ; Sang il MIN ; Sanghyun AHN ; Jongwon HA ; Seung Kee MIN
Vascular Specialist International 2017;33(1):33-36
A 71-year-old woman presented with an enlarging mass in the right buttock, with pain and tingling sensation in sitting position. Five years ago, she was diagnosed with acute limb ischemia due to acute thrombosis of right persistent sciatic artery (PSA), and she underwent successful thromboembolectomy and femoro-tibioperoneal trunk bypass. Computed tomography angiography revealed a huge PSA aneurysm (PSAA). During the previous bypass, the distal popliteal artery was ligated just above the distal anastomosis to exclude the PSAA, whose proximal end was already thrombosed. However, PSAA has grown to cause compression symptoms, and the mechanism of aneurysm growth can be ascribed to type 1a or type 2 endoleak. In order to relieve the compression symptoms, aneurysm excision was performed without any injury to the sciatic nerve. A postoperative tingling sensation due to sciatic-nerve stimulation in the supine position resolved spontaneously one month after surgery.
Aged
;
Aneurysm*
;
Angiography
;
Arteries*
;
Buttocks
;
Congenital Abnormalities
;
Endoleak
;
Extremities
;
Female
;
Humans
;
Ischemia
;
Popliteal Artery
;
Sciatic Nerve
;
Sciatica
;
Sensation
;
Supine Position
;
Thrombosis
8.A case of Nontraumatic Cerebrospinal Fluid Fistula.
Dong Kuck LEE ; Gun Min SHIN ; Sang Do YI ; Young Choon PARK
Journal of the Korean Neurological Association 1987;5(1):70-74
We reported a case of nontraumatic cerebrospinal fluid fistula who had concomittantly CSF rhinorrhea, pneumocephalus and bacterial meningitis. By metrizamide CT cisternography, we found her CSF fistula was likely to be on the right lateral wall of sphenoidal sinus. She was recovered from her symptoms by medical treatment and has been free of CSF rhinorrhea or meningitis without surgical repair of CSF fistula during recent 1 year follow up.
Cerebrospinal Fluid*
;
Fistula*
;
Follow-Up Studies
;
Meningitis
;
Meningitis, Bacterial
;
Metrizamide
;
Pneumocephalus
9.Two Cases of Holmes-Adie Syndrome.
Sang Won YI ; Sung Min YOON ; Kwang Soo KIM ; Kyung Mu YOO
Journal of the Korean Neurological Association 1998;16(4):582-584
BACKGROUND: Adie's tonic pupil consists of mydriasis, accommodation defect, decreased light reflex, and tonic near reflex. When tonic pupil is combined with hypo- or areflexia, it is called Holmes-Adie syndrome. CASE: Fifty-two-year-old and 37-year-old female patients showed unilateral dilated irregular pupil, decreased light reflex, and decreased or absent DTR. When 0.125% pilocarpine was dropped on the dilated pupil, the pupil was constricted after pilocarpine application. Somatosensory evoked potentials were within normal ranges, and H-reflex responses were absent or delayed.
Adie Syndrome*
;
Adult
;
Evoked Potentials, Somatosensory
;
Female
;
H-Reflex
;
Humans
;
Mydriasis
;
Pilocarpine
;
Pupil
;
Reference Values
;
Reflex
;
Tonic Pupil
10.A case of wilson's disease showing palialia as an initial symptom.
Sung Min YOON ; Sang Won YI ; Kwang Soo KIM ; Kyung Mu YOO
Journal of the Korean Neurological Association 1997;15(2):413-416
Wilson's disease is an autosomal recessive disorder resulting from an excessive accumulation of copper in the liver, cornea, kidneys, and in the basal ganglia of the brain. The prominent speech disturbances of Wilson's disease include monopitch, monoloudness, slow rate, low pitch, delayed in initiating speech and rarely palilalia. A19-year-old woman developed palilalia which was characterized by compulsive repetition of a phrase with increasing rapidity and with a decrescendo of voice volume. Although she had been suffering from liver cirrhosis for the past 8 months, the palilalia was the only neurological sign at initial examination. She showed a low serum ceruloplasmin, low serum copper, increased urinary copper excretion, and Kayser-Fleischer rings. Brain magnetic resonance images showed high signals in the bilateral basal ganglia in T2-weighted images, and slight cortical atrophy.
Atrophy
;
Basal Ganglia
;
Brain
;
Ceruloplasmin
;
Copper
;
Cornea
;
Female
;
Hepatolenticular Degeneration*
;
Humans
;
Kidney
;
Liver
;
Liver Cirrhosis
;
Voice