No abstract available.
Blood Platelets* ; Humans ; Infant, Newborn*

In order to evaluate the effect on nimodipine on the cerebral vasospasm, twelve adult mongrel dogs were studied in this experiment. This animals were divided into 2 groups ; Intracisternal injection of autogenous blood(Group I : no treatment group) and intravenous nimodipine administration after intracisternal injection of autogenous blood(Group II : treatment group). Nimodipine was administered 12 hours after intracisternal injection of autogenous blood for 7 days. Dogs were sacrificed at 8th day after intracisternal injection of autogenous blood and the unltrastructual changes were studied. The results were as follows : In Group I basilar artery showed endothelial cell swelling with distruption of intercellular junction, subendothelial edema and thickening of the internal elastic lamina with marked edematous change. The pathologic changes of arteries in Group II were considered more favorable than that of Group I. These results suggest that early intravenous treatment with nimodipine is beneficial in the treatment of vasospasm of this models.
Adult ; Animals ; Arteries ; Basilar Artery ; Dogs ; Edema ; Endothelial Cells ; Humans ; Intercellular Junctions ; Nimodipine* ; Vasospasm, Intracranial*

No abstract available.
Child* ; Diabetes Mellitus* ; Humans ; Insulin*

No abstract available.

TO determine the normal neonatal adrenal gland size, ultrasonographic examinations were performed in 145 newborn infants. They were divided into 3 groups according to the days of age. The group I is 1~3 days, group II is 6~9 days and group III is 21~50 days of age. 1) The adrenal gland size was as follows. In group I, the length was 29.05mm and the width was 4.02mm. In group II, the length was 24.04mm and the width was 2.79mm. In group III, the length was 19.54mm and the width was 2.21mm. 2) With increasing age, the size of adrenal gland became smaller. 3) The size of adrenal gland correlated well with the birth weight and height. We conclude that the ultrasonographic examination is useful in infant adrenal gland disease.
Adrenal Gland Diseases ; Adrenal Glands* ; Birth Weight ; Humans ; Infant ; Infant, Newborn

No abstract available.
Hemorrhage*

No abstract available.

Sjogren-Larsson Syndrome is a rare disorder chracterized by congenital icthyosis, spastic diplegia or tetraplegia and mental retardation. The inheritance is autosomal recessive, due to deficiency of alcohol dehydrogenase activity of fatty acid matabolism. We have experienced a case of Sjogren-Larsson Syndrome in a 16 month-old male children who have dried thick skin, developmental delay, and spastic diplegia. He also has glistening spot on macula area with irregular high voltage slow wave (2-3Hz) on electroencephalography. From Biopsy finding, Lamella ictyosis with acanthosis and hyperkeratosis in epithelium is shown. He was much improved clinically for skin lesion and developmental status with etretinate supplement. We report the case with brief review of related literatures.
Acitretin ; Alcohol Dehydrogenase ; Biopsy ; Cerebral Palsy ; Child ; Electroencephalography ; Epithelium ; Etretinate ; Humans ; Infant ; Intellectual Disability ; Male ; Quadriplegia ; Sjogren-Larsson Syndrome* ; Skin ; Wills

Iron deficiency remains the most common cause of anemia in infants and chidren despite increasing availability of iron-fortified foods. We screened out anemia in 9-month old infants in well baby clinic to know the prevalence of anemia and the weaning status. The results were as follows: 1) Among 345 infants screened, 24 infants (7%) were found to have anemia. 2) The kind of anemia was microcytosis and 7 infants (2.2%) revealed hypochromia. 3) Among the remaining 311 non-anemic infants, 6 infants (1.9%) revealed microcytosis and 7 infants (2.2%) revealed hypochromia. 4) In anemic group the mean hemoglobin concentration was 8.75+/-1.03gm/dl, hematocrit was 27. 73+/-3.11%, MCV was 65.84+/-8.21 fL, MCHwas 20.95+/-2.93 pg and MCHC was 31.34+/-1.89 gm/dl. 5) In 9 anemic infants, weaning was delayed until 9 months of age.
Anemia* ; Hematocrit ; Humans ; Infant* ; Iron ; Mass Screening* ; Prevalence ; Weaning

No abstract available.
Crohn Disease*